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The map label for this gene is yidC [H]

Identifier: 21672310

GI number: 21672310

Start: 14917

End: 16530

Strand: Direct

Name: yidC [H]

Synonym: BUsg016

Alternate gene names: 21672310

Gene position: 14917-16530 (Clockwise)

Preceding gene: 21672309

Following gene: 21672311

Centisome position: 2.33

GC content: 26.21

Gene sequence:

>1614_bases
ATGATGGAATTACAGCGTAATTTTTTTATTTTTGCTTTTTTGTTTGTTTCTTTTTTATTATGGCAAGCATGGCAGAGTCA
ATCTTTAAAAAAAAATAAAAAAAATGAAGAAACTAATTCGTTTTTTCATTTGAATCATAAAAAAGAAGATAAAAATCAAA
TAATTATTAAAAATGACGTACTTCGTTTAGTGATAAATATGTATGGAGGTGATATAGAAGAAGCAAGTTTACTTGATTAT
AAAACTCAATTAAATTCTCCTGAGAATTTGAAATTATTAGAAACAAAATCTGATTTTGTTTATCAGGCTCAAAGTGGATT
GATTGGAAAAGATGGTTTAGATAATTCAATTAATAAAATTAGACCATTGTATTCTGCAAAAAAAAATTTTTTTGAATTAG
GTCATAATGAAAAAGAATTACGTGTTCCAATAACTTTTATTGCCAAAAATGGGATAACGTATATAAAAAATTTTATCCTT
AAACCTGGTAAATATAATGTAGAAGTAGAATATGATATTAATAATTTGAGTAATAAAAAATTAGAACTAAATATTTTTGG
ACAACTAAAACAAACTGTTAAACTGCCTAAAAATCGTGATATTTATAGTGGTAATTTTGCCCTTCAGACTTTTCGTGGTG
CTGCTTATTCAAGTTCAGATGCGAAATATGAAAAATATAAATTTGATAATATCGCTAATCATGAACATCTTCATATCATT
ACTCATCATGGTTGGATCGCCATGCTGCAACAGTATTTTGTAGTTGCTTGGGTACCTGATACTAACATCAGCAGTTCTAA
TATAATTTATACATCTTATCTAGATAATGATGGTATTGCTATAATTGGATATAAGTCTTCTTTAATTAACATTCCATCTA
ATTCTAGATACATTATAAAATCTAAATTATGGATAGGACCTGAAAAACAGCAAGAGATGGCGCTAGTAGCACCAAATTTA
GATTTAACAGTAGATTATGGTTTCCTTTGGTTTTTATCTCAACCTTTATTTAAATTATTAAGTACTATACATAATTTTAT
AGGAAATTGGGGTTTTTCTATTATTTTAATTACTTTTATGATGAAAGCAATTACTTATCCGTTGACTAAAGCGCAATATA
CTTCTATGTCAAAAATGCGTGAATTACAACCGAAAATTAATGAGTTAAAGAAAAATTTCGGACATGATAAGCAACGGATG
AGCAAAGAAATAATGGCTTTATATAAGAAAGAAAAAATAAATCCATTAGGCGGTTGTTTGCCAGTTTTTATTCAAATGCC
TATTTTTTTATCTCTTTACTATATGTTAATTGGTTCTGTGGAACTACGTCATGCACCCTTTTTGTTTTGGATAAAAGATT
TATCTGATCAGGATCCATATTATGTTTTACCGATATTTATGGGTTTAACTATGTTTTTTATCCAAAGAACATCGTCTAAT
AATATTTCAGATCCTTTTCAACAAAAAATAATGCATTTTATGCCTTTTATTTTTACAGTGTTTTTTTTGTGGTTTCCATC
AGGATTAGTTTTATACTATATTGTTAGTAATTTAGTTACTATTATACAACAAAAATATATTTTATCTAATTTTAAAAAAA
ATCAAAAAAGATAA

Upstream 100 bases:

>100_bases
GTATAATTTTAACAATTTTACGTTTATTTAAATGTCATCCATTGCATCAAGGTGGAGAAGATTTAGTGCCTTTAAAAATT
AAAGATAAAAGTGAATATTA

Downstream 100 bases:

>100_bases
AAATTATTTATTCTTTTTATTTAAAAATTAAGAAAATATTTTATGATTCGAAATGATACTATTATTGCTCAAGTTACCTG
TCCTGGAAAAAGTGCTGTTG

Product: inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MMELQRNFFIFAFLFVSFLLWQAWQSQSLKKNKKNEETNSFFHLNHKKEDKNQIIIKNDVLRLVINMYGGDIEEASLLDY
KTQLNSPENLKLLETKSDFVYQAQSGLIGKDGLDNSINKIRPLYSAKKNFFELGHNEKELRVPITFIAKNGITYIKNFIL
KPGKYNVEVEYDINNLSNKKLELNIFGQLKQTVKLPKNRDIYSGNFALQTFRGAAYSSSDAKYEKYKFDNIANHEHLHII
THHGWIAMLQQYFVVAWVPDTNISSSNIIYTSYLDNDGIAIIGYKSSLINIPSNSRYIIKSKLWIGPEKQQEMALVAPNL
DLTVDYGFLWFLSQPLFKLLSTIHNFIGNWGFSIILITFMMKAITYPLTKAQYTSMSKMRELQPKINELKKNFGHDKQRM
SKEIMALYKKEKINPLGGCLPVFIQMPIFLSLYYMLIGSVELRHAPFLFWIKDLSDQDPYYVLPIFMGLTMFFIQRTSSN
NISDPFQQKIMHFMPFIFTVFFLWFPSGLVLYYIVSNLVTIIQQKYILSNFKKNQKR

Sequences:

>Translated_537_residues
MMELQRNFFIFAFLFVSFLLWQAWQSQSLKKNKKNEETNSFFHLNHKKEDKNQIIIKNDVLRLVINMYGGDIEEASLLDY
KTQLNSPENLKLLETKSDFVYQAQSGLIGKDGLDNSINKIRPLYSAKKNFFELGHNEKELRVPITFIAKNGITYIKNFIL
KPGKYNVEVEYDINNLSNKKLELNIFGQLKQTVKLPKNRDIYSGNFALQTFRGAAYSSSDAKYEKYKFDNIANHEHLHII
THHGWIAMLQQYFVVAWVPDTNISSSNIIYTSYLDNDGIAIIGYKSSLINIPSNSRYIIKSKLWIGPEKQQEMALVAPNL
DLTVDYGFLWFLSQPLFKLLSTIHNFIGNWGFSIILITFMMKAITYPLTKAQYTSMSKMRELQPKINELKKNFGHDKQRM
SKEIMALYKKEKINPLGGCLPVFIQMPIFLSLYYMLIGSVELRHAPFLFWIKDLSDQDPYYVLPIFMGLTMFFIQRTSSN
NISDPFQQKIMHFMPFIFTVFFLWFPSGLVLYYIVSNLVTIIQQKYILSNFKKNQKR
>Mature_537_residues
MMELQRNFFIFAFLFVSFLLWQAWQSQSLKKNKKNEETNSFFHLNHKKEDKNQIIIKNDVLRLVINMYGGDIEEASLLDY
KTQLNSPENLKLLETKSDFVYQAQSGLIGKDGLDNSINKIRPLYSAKKNFFELGHNEKELRVPITFIAKNGITYIKNFIL
KPGKYNVEVEYDINNLSNKKLELNIFGQLKQTVKLPKNRDIYSGNFALQTFRGAAYSSSDAKYEKYKFDNIANHEHLHII
THHGWIAMLQQYFVVAWVPDTNISSSNIIYTSYLDNDGIAIIGYKSSLINIPSNSRYIIKSKLWIGPEKQQEMALVAPNL
DLTVDYGFLWFLSQPLFKLLSTIHNFIGNWGFSIILITFMMKAITYPLTKAQYTSMSKMRELQPKINELKKNFGHDKQRM
SKEIMALYKKEKINPLGGCLPVFIQMPIFLSLYYMLIGSVELRHAPFLFWIKDLSDQDPYYVLPIFMGLTMFFIQRTSSN
NISDPFQQKIMHFMPFIFTVFFLWFPSGLVLYYIVSNLVTIIQQKYILSNFKKNQKR

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=540, Percent_Identity=57.037037037037, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI24662345, Length=196, Percent_Identity=26.0204081632653, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356443, Length=196, Percent_Identity=26.0204081632653, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 62792; Mature: 62792

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMELQRNFFIFAFLFVSFLLWQAWQSQSLKKNKKNEETNSFFHLNHKKEDKNQIIIKNDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEHHH
LRLVINMYGGDIEEASLLDYKTQLNSPENLKLLETKSDFVYQAQSGLIGKDGLDNSINKI
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHEECCCCCCCCCCCCCHHHHH
RPLYSAKKNFFELGHNEKELRVPITFIAKNGITYIKNFILKPGKYNVEVEYDINNLSNKK
HHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCEEEEEEEECCCCCCCE
LELNIFGQLKQTVKLPKNRDIYSGNFALQTFRGAAYSSSDAKYEKYKFDNIANHEHLHII
EEEEEHHHHHHHHCCCCCCCEECCCEEEEECCCCCCCCCCCCHHHEECCCCCCCCEEEEE
THHGWIAMLQQYFVVAWVPDTNISSSNIIYTSYLDNDGIAIIGYKSSLINIPSNSRYIIK
EECCHHHHHHHHEEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCEEECCCCCEEEEE
SKLWIGPEKQQEMALVAPNLDLTVDYGFLWFLSQPLFKLLSTIHNFIGNWGFSIILITFM
EEEECCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MKAITYPLTKAQYTSMSKMRELQPKINELKKNFGHDKQRMSKEIMALYKKEKINPLGGCL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHH
PVFIQMPIFLSLYYMLIGSVELRHAPFLFWIKDLSDQDPYYVLPIFMGLTMFFIQRTSSN
HHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCC
NISDPFQQKIMHFMPFIFTVFFLWFPSGLVLYYIVSNLVTIIQQKYILSNFKKNQKR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMELQRNFFIFAFLFVSFLLWQAWQSQSLKKNKKNEETNSFFHLNHKKEDKNQIIIKNDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEHHH
LRLVINMYGGDIEEASLLDYKTQLNSPENLKLLETKSDFVYQAQSGLIGKDGLDNSINKI
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHEECCCCCCCCCCCCCHHHHH
RPLYSAKKNFFELGHNEKELRVPITFIAKNGITYIKNFILKPGKYNVEVEYDINNLSNKK
HHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCEEEEEEEECCCCCCCE
LELNIFGQLKQTVKLPKNRDIYSGNFALQTFRGAAYSSSDAKYEKYKFDNIANHEHLHII
EEEEEHHHHHHHHCCCCCCCEECCCEEEEECCCCCCCCCCCCHHHEECCCCCCCCEEEEE
THHGWIAMLQQYFVVAWVPDTNISSSNIIYTSYLDNDGIAIIGYKSSLINIPSNSRYIIK
EECCHHHHHHHHEEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCEEECCCCCEEEEE
SKLWIGPEKQQEMALVAPNLDLTVDYGFLWFLSQPLFKLLSTIHNFIGNWGFSIILITFM
EEEECCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MKAITYPLTKAQYTSMSKMRELQPKINELKKNFGHDKQRMSKEIMALYKKEKINPLGGCL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHH
PVFIQMPIFLSLYYMLIGSVELRHAPFLFWIKDLSDQDPYYVLPIFMGLTMFFIQRTSSN
HHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCC
NISDPFQQKIMHFMPFIFTVFFLWFPSGLVLYYIVSNLVTIIQQKYILSNFKKNQKR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9516544; 12089438; 1572539 [H]