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The map label for this gene is dppE [H]

Identifier: 30263535

GI number: 30263535

Start: 3352245

End: 3353933

Strand: Reverse

Name: dppE [H]

Synonym: BA_3645

Alternate gene names: 30263535

Gene position: 3353933-3352245 (Counterclockwise)

Preceding gene: 30263536

Following gene: 30263534

Centisome position: 64.16

GC content: 34.64

Gene sequence:

>1689_bases
ATGAAAAAACTAACAGCAGTTGTAGCACCAGTTTTAGCAATGAGTATGGCATTAACAGCATGTTCTACATCAGGTGGAGA
TAAGAAGACAAGCACAAATTCTAGCTCTGGCGGAGATAGCAAATCAGAAGAAAAATTAGCAGCGAAACAAGTGTTCAATA
AAACAGAAAATCAGGAAATTCCAACAATGGATACGTCGAAGAGTACAGATACTTTGGGCTCTCAAATTTTAGGGAACACA
ATGGAAGGCTTATACCGTTTAGATAAAGAGAATAAACCAATCCCAGCTGCGGCAGAATCAAGCACGAAGAGTGAGGATGG
TAAAAAATATACATTTAAATTACGTAAAGATGCAAAATGGTCAAATGGTGATTCTGTAACAGCGAAAGATTTCGTATTTG
CATGGCAACGTTTGTTAGATCCAAAAACAGCTGCTGAGTATGCATTCATTGCATTCCCAATTAAAAATGCAGAAGCGGTT
AATAAAGGGGAAAAACCTGTAACAGAACTAGGAGTTAAAGCAGTAGATGACCTTACTTTAGAAGTTGAATTAGAACAAGC
AGTACCATACTTCTTAAACTTAGTAGCATTCCCATCATACTATCCATTAAATGAGAAATTCGTAAAAGAAAAAGGGGATA
AATACGGTTTAGAATCTGATACAACTGTATATAACGGACCGTTCGTTCTTACTGATTGGAAGCATGAGCAAGGCTGGAAA
CTGAAGAAGAATGATCAATATTGGGATAAAAAGACTGTAAAATTAGATGAAATTAACTATAGTGTTGTAAAAGAGCCAGC
AACTAATGTGAATTTATATGATAGTGGTCAAATTGATTTCTCCTTATTAACAGGTGAATTTGTTGACAAATATAGAAATA
ATAAAGAGGAATATGGGGTGTATAACGAACCAAGTACGTTCTTTATACGTTTAAACCAAAAACGTGGTGGACAAGATACA
CCATTAAAGAGTAAAAAATTACGTGAAGCAATTGCGCTATCAATTGATAAAAAGAATTTAACAAATGTAATTTTAAATGA
TGGGTCAAAACCTGCAGATTATTTAGTGCCGAAAGGATTAGCAGCTGGACCTGATGGAAAAGACTTCCAAGAAACGTTTA
AAAACGGTGTTAAACCAGATGCGAAAAAAGCAGCTGCTGCATGGGAAGAAGCGAAAAAAGAACTTGGAAAAGATCAAGTT
ACAATTGAGTTTTTAAACTATGATACTGGTAATGCGAAAAAAGTTGGGGAATATGTAAAAGATCAAATTGAGAAAAACTT
AAAAGGTGTAACAGTAAATATTAAACTGCAACCGTTTAAACAAAAACTTAAATTAGAATCAGATCAAGATTATGATATTT
CATATGGTGGATGGAGCCCAGATTATGCGGATCCAATGACATATTTAGATATGTTTGAAAGTAAGCACTCTCATAACCAA
ATGAGTTTCTCTGATCAGAAATATGATGAAATAATCAAAAAAGCTGGTGGAGAATTAATGACTGATGCGAAGAAACGCTG
GGAGGAGCTAGGAAAAGCAGAGGAATTACTTCTTGAAGAAGATGTTGCCCTTGTACCTTTATATCAAAGTGCTAGATCTT
ATGTTATGAAACCGCATGTAAAAGGTGTTGTTAAGCATAATATTAGCCCAGAATACAGCTATAAGTGGGCATATGTTACT
GAAAAATAA

Upstream 100 bases:

>100_bases
AATCTTCTGATAAATATATAAAGAAAAACAGAATTATCAGAAAATTCTTAAATGAGAGCGTTAAGAATTAGGGAGGGTAC
AGAAAGTGAAAAAGAAAAAA

Downstream 100 bases:

>100_bases
TAGAGTTGAAAAAGTACTTCAAAGCAGTCTACATGCCTTGAAGTACTTTTTTTATTGTACGATTGAACGCGAAAATGAAA
GAGTGGAGAAGAAATGAAAT

Product: oligopeptide ABC transporter, oligopeptide-binding protein, putative

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVFNKTENQEIPTMDTSKSTDTLGSQILGNT
MEGLYRLDKENKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDSVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAV
NKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKHEQGWK
LKKNDQYWDKKTVKLDEINYSVVKEPATNVNLYDSGQIDFSLLTGEFVDKYRNNKEEYGVYNEPSTFFIRLNQKRGGQDT
PLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQETFKNGVKPDAKKAAAAWEEAKKELGKDQV
TIEFLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLESDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQ
MSFSDQKYDEIIKKAGGELMTDAKKRWEELGKAEELLLEEDVALVPLYQSARSYVMKPHVKGVVKHNISPEYSYKWAYVT
EK

Sequences:

>Translated_562_residues
MKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVFNKTENQEIPTMDTSKSTDTLGSQILGNT
MEGLYRLDKENKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDSVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAV
NKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKHEQGWK
LKKNDQYWDKKTVKLDEINYSVVKEPATNVNLYDSGQIDFSLLTGEFVDKYRNNKEEYGVYNEPSTFFIRLNQKRGGQDT
PLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQETFKNGVKPDAKKAAAAWEEAKKELGKDQV
TIEFLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLESDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQ
MSFSDQKYDEIIKKAGGELMTDAKKRWEELGKAEELLLEEDVALVPLYQSARSYVMKPHVKGVVKHNISPEYSYKWAYVT
EK
>Mature_562_residues
MKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVFNKTENQEIPTMDTSKSTDTLGSQILGNT
MEGLYRLDKENKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDSVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAV
NKGEKPVTELGVKAVDDLTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKHEQGWK
LKKNDQYWDKKTVKLDEINYSVVKEPATNVNLYDSGQIDFSLLTGEFVDKYRNNKEEYGVYNEPSTFFIRLNQKRGGQDT
PLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGLAAGPDGKDFQETFKNGVKPDAKKAAAAWEEAKKELGKDQV
TIEFLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLESDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQ
MSFSDQKYDEIIKKAGGELMTDAKKRWEELGKAEELLLEEDVALVPLYQSARSYVMKPHVKGVVKHNISPEYSYKWAYVT
EK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=553, Percent_Identity=30.5605786618445, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1789397, Length=520, Percent_Identity=29.0384615384615, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI87081878, Length=542, Percent_Identity=28.4132841328413, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787762, Length=458, Percent_Identity=25.9825327510917, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1787052, Length=485, Percent_Identity=23.9175257731959, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789887, Length=516, Percent_Identity=22.6744186046512, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789966, Length=475, Percent_Identity=22.7368421052632, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63202; Mature: 63202

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVFNKTENQEI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
PTMDTSKSTDTLGSQILGNTMEGLYRLDKENKPIPAAAESSTKSEDGKKYTFKLRKDAKW
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
SNGDSVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAVNKGEKPVTELGVKAVDDLTL
CCCCCCCHHHHHHHHHHHCCCCHHHCEEEEEEECCCCHHHCCCCCCHHHHCCHHHCCEEE
EVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKHEQGWK
EEEHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCCCC
LKKNDQYWDKKTVKLDEINYSVVKEPATNVNLYDSGQIDFSLLTGEFVDKYRNNKEEYGV
CCCCCCCCCCCCEEEECCCHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHCCHHHCCC
YNEPSTFFIRLNQKRGGQDTPLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGL
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHCCCCC
AAGPDGKDFQETFKNGVKPDAKKAAAAWEEAKKELGKDQVTIEFLNYDTGNAKKVGEYVK
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHH
DQIEKNLKGVTVNIKLQPFKQKLKLESDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQ
HHHHCCCCEEEEEEEECCHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCC
MSFSDQKYDEIIKKAGGELMTDAKKRWEELGKAEELLLEEDVALVPLYQSARSYVMKPHV
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEHHHHHHHHCCCHH
KGVVKHNISPEYSYKWAYVTEK
HHHHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVFNKTENQEI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
PTMDTSKSTDTLGSQILGNTMEGLYRLDKENKPIPAAAESSTKSEDGKKYTFKLRKDAKW
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
SNGDSVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAVNKGEKPVTELGVKAVDDLTL
CCCCCCCHHHHHHHHHHHCCCCHHHCEEEEEEECCCCHHHCCCCCCHHHHCCHHHCCEEE
EVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKHEQGWK
EEEHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCCCC
LKKNDQYWDKKTVKLDEINYSVVKEPATNVNLYDSGQIDFSLLTGEFVDKYRNNKEEYGV
CCCCCCCCCCCCEEEECCCHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHCCHHHCCC
YNEPSTFFIRLNQKRGGQDTPLKSKKLREAIALSIDKKNLTNVILNDGSKPADYLVPKGL
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHCCCCC
AAGPDGKDFQETFKNGVKPDAKKAAAAWEEAKKELGKDQVTIEFLNYDTGNAKKVGEYVK
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHH
DQIEKNLKGVTVNIKLQPFKQKLKLESDQDYDISYGGWSPDYADPMTYLDMFESKHSHNQ
HHHHCCCCEEEEEEEECCHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCC
MSFSDQKYDEIIKKAGGELMTDAKKRWEELGKAEELLLEEDVALVPLYQSARSYVMKPHV
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEEEEHHHHHHHHCCCHH
KGVVKHNISPEYSYKWAYVTEK
HHHHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]