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The map label for this gene is dppE [H]

Identifier: 30263534

GI number: 30263534

Start: 3350231

End: 3351937

Strand: Reverse

Name: dppE [H]

Synonym: BA_3644

Alternate gene names: 30263534

Gene position: 3351937-3350231 (Counterclockwise)

Preceding gene: 30263535

Following gene: 30263533

Centisome position: 64.12

GC content: 35.79

Gene sequence:

>1707_bases
ATGAAGAAAAAGATGAAGAAGTTCACGGCAGTTGTAGCGCCTGTTTTAGCGATGAGTGTGGCGTTGACAGCTTGTTCTGG
ATCTGGTGGGGAGAAGAAATCAACTACGACGTCTAGTGGTGGTGGGGAAGAGAAAAAGTCTGAAATTAAATACGCAGCGA
AACAAGTGTTAAATCGTACAGAGAATCAAGAGATTCCGACGATGGATGTTTCAAAATCTACCGATACATTAGGTTCTCAA
ATTTTAGGGAACACGATGGAAGGTTTATATCGATTAGATAAAGATAATAAGCCAATCCCAGCTGCAGCAGAATCTAGTAC
GAAAAGCGAGGATGGCAAAAAATATACATTTAAATTACGTAAAGATGCAAAATGGTCAAATGGTGATCCTGTAACAGCGA
AAGATTTCGTATATGCATGGCAGCGCTTACTTGATAAAAATACAGCGGCAGAATATGCATTTATTGCTTACTATATTAAA
AACGCAGAGGCAATTAATAAAGGTGAAAAACCACTAACAGATTTAGGAGCAAAAGCGGTAGATGATTATACGCTAGAAGT
AGAATTAGAGAAACCAGTACCATATTTCTTGAATTTAATGGCATTCCCATCTTACTATCCTTTAAATGAAAAGTTCGTAA
AAGAAAAAGGAGATAAATTCGGTTTAGAAGCAGATACAACGTTGTATAACGGACCGTTCGTTATGGCTTCATGGAAACAT
GAACAAGGATGGCAGCTAAAGAAAAATGATAAGTACTGGGATAATAAGACTGTAAAATTAGAAGAAATTAACTATAGTGT
AGTAAAAGAAGTTGCGACGAAAGTAAACTTATATGATACAGGATCAATTGATTTCACGTTATTATCAGGAGAATTCGTTG
ATAAATATAAATCGAACAAAGAAGAGTACGGCGAGTATTCGGAAGCAAGTACATTCTTCTTACGTTTAAATCAAAAGCGT
AACGGACAAGATACACCGTTAAAGAGCAAAAAACTTCGTGAAGCGATCGCATTATCAATTGATAAAAAAGGATTAGCAAC
CGTTATTTTAAATAACGGTTCAAAAGCAACAGATCAATTAGTACCAAAAGGGCTTGCGACAGGACCAGACGGTAAAGACT
ACCAAGATACGTTTAAAAATGGTCTAAAATATGATCCGAAAAAAGGTGCAGCAGCTTGGGAAGAAGCGAAAAAAGAACTT
GGAAAAGATCAAGTGACAATTGAATTACTAAGCTATGATGATGGAACTGCGAAAAAAATTGCTGACTACTTTAAAGATCA
AATTGAGAAAAACTTAAAAGGTGTAACGGTTAACACGAAAATTCAACCGTTCAAACAAAAACTAAAATTAGAGTCAGCAC
AAGATTATGAAGTTTCGTTTGCAGGTTGGAGTCCAGATTATTCGGATCCAATGACATTTATTGATATGTTTGAATCGAAG
AGCCCATATAACCAAATGAGTTATTCGAATCCAAAATATGATGAAATGGTAGCGAAAGCAGGTAATGAATTACTGTCTGA
TCCGAAGAAGCGTTGGGAAACGTTAGGAAAAGCAGAGAAATTATTCCTTGAAGAAGATGCAGGATTAGTTCCTTTATATC
AAACAGGAAGAGCGTATGTAATGAAACCGAATGTAAAAGGAATTGTGAAACATAACATTAGTCCAGAATATAGCTTTAAG
TGGGCTTATGTAACGGAAGGTAAATAA

Upstream 100 bases:

>100_bases
AAAATTAGTAGAATATTAATTAACAAGAATTTTCTGATAACTAGTTATTAGAAAATCTCTCAAAATGAGTTTCGTACATA
TAATTGGGGAGGGTACAAAA

Downstream 100 bases:

>100_bases
TAAAAAAGAGCGTGTTTAAAAGTAGATAAGTTATTTTTAACACGCTCTTTTTATATTCAATTAAATAGAGAAGAATAAGA
AATGTGGTACTGACATATAG

Product: oligopeptide ABC transporter, oligopeptide-binding protein, putative

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKKKMKKFTAVVAPVLAMSVALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRTENQEIPTMDVSKSTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAYYIK
NAEAINKGEKPLTDLGAKAVDDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNKEEYGEYSEASTFFLRLNQKR
NGQDTPLKSKKLREAIALSIDKKGLATVILNNGSKATDQLVPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEEAKKEL
GKDQVTIELLSYDDGTAKKIADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYVMKPNVKGIVKHNISPEYSFK
WAYVTEGK

Sequences:

>Translated_568_residues
MKKKMKKFTAVVAPVLAMSVALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRTENQEIPTMDVSKSTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAYYIK
NAEAINKGEKPLTDLGAKAVDDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNKEEYGEYSEASTFFLRLNQKR
NGQDTPLKSKKLREAIALSIDKKGLATVILNNGSKATDQLVPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEEAKKEL
GKDQVTIELLSYDDGTAKKIADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYVMKPNVKGIVKHNISPEYSFK
WAYVTEGK
>Mature_568_residues
MKKKMKKFTAVVAPVLAMSVALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRTENQEIPTMDVSKSTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAYYIK
NAEAINKGEKPLTDLGAKAVDDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNKEEYGEYSEASTFFLRLNQKR
NGQDTPLKSKKLREAIALSIDKKGLATVILNNGSKATDQLVPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEEAKKEL
GKDQVTIELLSYDDGTAKKIADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYVMKPNVKGIVKHNISPEYSFK
WAYVTEGK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=551, Percent_Identity=31.5789473684211, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=29.2730844793713, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87081878, Length=536, Percent_Identity=27.9850746268657, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1787762, Length=455, Percent_Identity=27.9120879120879, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787052, Length=512, Percent_Identity=23.2421875, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789887, Length=336, Percent_Identity=26.7857142857143, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789966, Length=483, Percent_Identity=23.1884057971014, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63855; Mature: 63855

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMKKFTAVVAPVLAMSVALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
ENQEIPTMDVSKSTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAYYIKNAEAINKGEKPLTDLGAKAV
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEEHEECCHHHHCCCCCCHHHHCCHHC
DDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
CCEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEEECCC
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNK
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCEEECCCEEEEEECCHHHHHHHCCH
EEYGEYSEASTFFLRLNQKRNGQDTPLKSKKLREAIALSIDKKGLATVILNNGSKATDQL
HHHCCHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
VPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEEAKKELGKDQVTIELLSYDDGTAKKI
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
ADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
HHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCC
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYV
CCCCCCCCCCCCHHHHHHHHCHHHHCCHHHHHHHHCHHHHHHEECCCCEEEEEECCCEEE
MKPNVKGIVKHNISPEYSFKWAYVTEGK
ECCCCCEEEECCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MKKKMKKFTAVVAPVLAMSVALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
ENQEIPTMDVSKSTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAYYIKNAEAINKGEKPLTDLGAKAV
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEEHEECCHHHHCCCCCCHHHHCCHHC
DDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
CCEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEEECCC
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNK
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCEEECCCEEEEEECCHHHHHHHCCH
EEYGEYSEASTFFLRLNQKRNGQDTPLKSKKLREAIALSIDKKGLATVILNNGSKATDQL
HHHCCHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
VPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEEAKKELGKDQVTIELLSYDDGTAKKI
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
ADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
HHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCC
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYV
CCCCCCCCCCCCHHHHHHHHCHHHHCCHHHHHHHHCHHHHHHEECCCCEEEEEECCCEEE
MKPNVKGIVKHNISPEYSFKWAYVTEGK
ECCCCCEEEECCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]