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The map label for this gene is pncB [H]

Identifier: 21244246

GI number: 21244246

Start: 4163564

End: 4164742

Strand: Reverse

Name: pncB [H]

Synonym: XAC3521

Alternate gene names: 21244246

Gene position: 4164742-4163564 (Counterclockwise)

Preceding gene: 21244247

Following gene: 21244245

Centisome position: 80.47

GC content: 63.61

Gene sequence:

>1179_bases
ATGATCATCCATTCGCTGCTCGACACCGATCTGTACAAATTCACCATGATGCAGGCGGTGCTGCACCAGCACCCGGCAGC
GCAGGTGGATTACCGCTTCAAATGCCGCACTCCCGGCGTGGACCTGGCGCAGTTCATCGATGAGATCTCGCGCGAGATCG
ATGCGCTGTGCCGGTTGCGGTTGCGCGAGGACGAAGTGGATTACCTGCGCAGCCTGCGCTTCATCAAGCCGGACTTCGCC
GACTTCCTGGCGCTGTTCCATCTGGATCGCAAGTATCTGAGCCTGACCGCATCGGCCACCCATCCGGGCGAGATCGAGCT
GACCATCCGCGGGCCGTGGTTGCACACCATCCTGTTCGAGGTGCCGCTGCTGGCGATCATCAACGAGGTCTGGTTCCGCA
ATACCTCCGAGCCGGATTTCGAAGAGGGCCGCAGCCGCCTGCGCGAAAAGGTAGCCAGCCTGCGCAGCATGCCGGCCGGC
TGCAAGATCGCCGATTACGGCACCCGGCGGCGCTACTCGCGGCAATGGCATGGCGAGTTGCTGCCGCTGCTGCGCGATGG
CCTGGGCGAGCAGTTCGTCGGCACCAGCAACGTGTACTTCGCCAAGCAGTACGGGCTGACCCCGCTGGGAACCATGGCGC
ACGAGTATCTGCAGGCGTTCCAGGCGTTGGGGCCGCGGCTGCGCGATTCGCAGGTGGCGGCGCTGGAATCGTGGGCGCGC
GAATACCGTGGCGATCTGGGTATCGCGTTGTCGGACGTGGTCGGGCTGGATGCGTTCCTGCGCGATTTCGATCTGTATTT
CTGCAAGTTGTTCGATGGCATGCGCCACGATTCGGGCGACCCGTTCGAATGGGGCGAGCGCGTCATCGCGCATCTGGAAG
CGCACCGCGTCGATCCCCGGACCAAGGTGCTGGTATTCAGCGACGGCCTCAATATCGACAAGGTGATGCGGCTGTACCAG
CACTTCCACACGCGCTGCCGGCTGGCCTTCGGGGTGGGCACCAGCCTCACCAACGATCTGGGGCCGACGCCGCTGCAGAT
CGTGATCAAGATGGTCCGCTGCAATGGCCAGCCGGTGGCCAAGCTCAGCGACTCGCCCGGCAAGAGCATGTGCGAGGACA
TCGGATATCTGCGCTATCTGCGCGACGTGTTCGGGTTGCCGCCGATGGCAGAGACATGA

Upstream 100 bases:

>100_bases
ATCGCCGGTCCGCGCCTGACGACACAGGTGCGCTGCGCCGTCGCGCGGGGCGTGCGCAGTGCACGCGCTGCCATCGCCGC
TAAGGGCATAATCCGGCGGC

Downstream 100 bases:

>100_bases
TCGATCGGGGCGACACCGCAGAAGAGTGACTGCAGGGTGACCACCCGCTCAGTAAATTCCCTACACACTGTCAGGGAATG
CCGGAAAAAGTGAGACGTAG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFIDEISREIDALCRLRLREDEVDYLRSLRFIKPDFA
DFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFEVPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAG
CKIADYGTRRRYSRQWHGELLPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPRTKVLVFSDGLNIDKVMRLYQ
HFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCEDIGYLRYLRDVFGLPPMAET

Sequences:

>Translated_392_residues
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFIDEISREIDALCRLRLREDEVDYLRSLRFIKPDFA
DFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFEVPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAG
CKIADYGTRRRYSRQWHGELLPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPRTKVLVFSDGLNIDKVMRLYQ
HFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCEDIGYLRYLRDVFGLPPMAET
>Mature_392_residues
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFIDEISREIDALCRLRLREDEVDYLRSLRFIKPDFA
DFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFEVPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAG
CKIADYGTRRRYSRQWHGELLPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPRTKVLVFSDGLNIDKVMRLYQ
HFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCEDIGYLRYLRDVFGLPPMAET

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=44.2748091603053, Blast_Score=336, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6324783, Length=407, Percent_Identity=29.2383292383292, Blast_Score=189, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 44920; Mature: 44920

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFIDEISREIDALCRLR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LREDEVDYLRSLRFIKPDFADFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFE
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCHHHHHHHH
VPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAGCKIADYGTRRRYSRQWHGEL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHH
LPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
HHHHHHCCCCHHCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
TKVLVFSDGLNIDKVMRLYQHFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCC
KLSDSPGKSMCEDIGYLRYLRDVFGLPPMAET
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFIDEISREIDALCRLR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LREDEVDYLRSLRFIKPDFADFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFE
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCHHHHHHHH
VPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAGCKIADYGTRRRYSRQWHGEL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHH
LPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
HHHHHHCCCCHHCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
TKVLVFSDGLNIDKVMRLYQHFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCC
KLSDSPGKSMCEDIGYLRYLRDVFGLPPMAET
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA