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The map label for this gene is bga [H]

Identifier: 21243805

GI number: 21243805

Start: 3610365

End: 3612188

Strand: Direct

Name: bga [H]

Synonym: XAC3078

Alternate gene names: 21243805

Gene position: 3610365-3612188 (Clockwise)

Preceding gene: 77748693

Following gene: 21243806

Centisome position: 69.76

GC content: 66.23

Gene sequence:

>1824_bases
GTGCCGGATGGTCGCCCGCATGTATTCGGCTTCGACCGCGGACAGTTCGTGCTGGACCAGCAGCCGTGGCAGTTGCGCAG
TGGCGAGATGCATCCGTTGCGCATCGCCCGTGCGGATTGGCTGCAGCGCATCCGCATGGCCAAGGCGATGGGCTTGAACA
CGATTGCGCTGTACCTGATGTGGAATGCCTACGAGCGCGAGCCGGGGCAGTTCGATTTCGCGACCGACGAGCGGGATTTC
GTCGCCTTCATCAAGCTCTGCCAGCAGGAAGGCATGTGGGTGTATCTGCGACCCGGCCCTTACGTGTGCGCCGAATGGAC
GCTGGGCGGGCTGCCGCCCTACCTGCTGCGCGAACCGGGCATGCGGTTACGCGACGCCAATGATGCACGTTACATGGCAG
CGGTACAGCGCTATATCGCCGCGGTGGCGCCACACCTCGCACCGCTGATGGCCGGTGCCGGCGGGCCGGTGCTGATGCTG
CAGATCGAGAACGAATACAGCATGCACGGCAGCGACGTGGGCTATCTGCAGGCGCTGGCTGCGCTTTGGCGCCAGCACGG
CATCGATGGCCCGTTTTCGCTGGCCGAAGGCATGAAGGACCTGCGCCGACGCAAGGCCTACCTGCCCGGCGCGGCGCTGG
GTCTGGATGGTGCGGATCTGCAGGAGTTACAGCAGGCCAGAACCATCGCAGGTGACGCACCGGTATGGGTGGCCGAAGGC
TACCCGGGCTGGTTGACGCATTGGGGCGATGCCGATGTGGCGCGCCGCGACTACGCACCGATGCTGCAGCACCTGATGGC
AGCCGGCTATTCGTTCAACCTGTATGTGGTGCACGGCGGCAGCAACTTCGGGCTGAGCGCTGGCGCCAATGCCGAAGACG
ACGGTTCGCAATTCCAGCCGGTGCTCACCAGCTACGACTACAGCGCACCGATCGACGAACGCGGCTGCGCCACGCCGGCC
TACACGGCACTGCGCAGCATCATCGCCCAACACAGCAGCGGCCCGCTGCCGGCGATTCCGGCGGCGCCAGCGCGCACCCG
CTTCGACGCGGTCATCGCACACCCGGTCGCATCGCTGTGGGACAACCTGGGAGACCAGCCGGTGCCTACCGACCAGCCTG
CCGACAACCAAACCCTGCTCAGGCAGAACCTGGGCCTGGCGGTCTACCGGCGCCGCATTGCCGCCGGCACGCAACTGGAC
CTGGGCCTGGTGCACGACTACGCAGCAGTCCACCTGGATGGCCGCGAGATCGGCCATGTCTCGCGCATGCGGCATGCGCA
CCTCAACAGTGCAACGCAACTCGCCCTGCCGAACGCCGCCGCGAAGGAACGCCAGCTCGACATGCTGGTCGACAGTTTCG
GCCATATCAATTTCGGCCCGGCACTGGGCGATGCCAAAGGCCTGCTCGGCCCGGTGCGACTGGATGGCAGCGAGCTGCGC
GGCTGGCAGGTGTACGGCTTAGCGCTGGATAGCGACACCGCGCCCACGTTGCGCCCACTGCAAGCGCCAGCCGCGCGCCC
CGGCCTGTTCTTCGCCGCCGATATCGCACTGCAAACGGTCGGCGACGTGTACCTGGACATGCGCCAGTGGCGCAAAGGCT
ATCTGTGGGTCAACGGACGCCTGTTGGGGCGTTACTGGAACGTCGGCCCGCAACAGTGCCTGTTCTGCCCCGGCGCTTGG
CTGCGCAAAGGCAACAATGCAGTGCTGGTGCTGGATCTGCATCAAATGGAAGCCACCGCGATCCACTGCGCCGACAGCCT
GCGCGCTGCCCATGACGCAGCCACCACAGCACGCAGCACGCATGCGGCGTACAGCGCATGCTGA

Upstream 100 bases:

>100_bases
TGGAGAGACGATGAAACGCAGGAGCCTATGCACGTTTGGGCTGCTCGCGCCGTTCGGCCTGGCGGCCGCGCCGGCGCTGC
TGTCGTCGCTGCGTGCGCCA

Downstream 100 bases:

>100_bases
GTCCCTCGGTGGTGCCGCCATCGTCCACAGCTGCAGGCGCCCCGCCGCGCACGCTGGGTTTCTGGAGCGCGCTGTCGGCC
AATCTGCTCAACATGATCGG

Product: beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MPDGRPHVFGFDRGQFVLDQQPWQLRSGEMHPLRIARADWLQRIRMAKAMGLNTIALYLMWNAYEREPGQFDFATDERDF
VAFIKLCQQEGMWVYLRPGPYVCAEWTLGGLPPYLLREPGMRLRDANDARYMAAVQRYIAAVAPHLAPLMAGAGGPVLML
QIENEYSMHGSDVGYLQALAALWRQHGIDGPFSLAEGMKDLRRRKAYLPGAALGLDGADLQELQQARTIAGDAPVWVAEG
YPGWLTHWGDADVARRDYAPMLQHLMAAGYSFNLYVVHGGSNFGLSAGANAEDDGSQFQPVLTSYDYSAPIDERGCATPA
YTALRSIIAQHSSGPLPAIPAAPARTRFDAVIAHPVASLWDNLGDQPVPTDQPADNQTLLRQNLGLAVYRRRIAAGTQLD
LGLVHDYAAVHLDGREIGHVSRMRHAHLNSATQLALPNAAAKERQLDMLVDSFGHINFGPALGDAKGLLGPVRLDGSELR
GWQVYGLALDSDTAPTLRPLQAPAARPGLFFAADIALQTVGDVYLDMRQWRKGYLWVNGRLLGRYWNVGPQQCLFCPGAW
LRKGNNAVLVLDLHQMEATAIHCADSLRAAHDAATTARSTHAAYSAC

Sequences:

>Translated_607_residues
MPDGRPHVFGFDRGQFVLDQQPWQLRSGEMHPLRIARADWLQRIRMAKAMGLNTIALYLMWNAYEREPGQFDFATDERDF
VAFIKLCQQEGMWVYLRPGPYVCAEWTLGGLPPYLLREPGMRLRDANDARYMAAVQRYIAAVAPHLAPLMAGAGGPVLML
QIENEYSMHGSDVGYLQALAALWRQHGIDGPFSLAEGMKDLRRRKAYLPGAALGLDGADLQELQQARTIAGDAPVWVAEG
YPGWLTHWGDADVARRDYAPMLQHLMAAGYSFNLYVVHGGSNFGLSAGANAEDDGSQFQPVLTSYDYSAPIDERGCATPA
YTALRSIIAQHSSGPLPAIPAAPARTRFDAVIAHPVASLWDNLGDQPVPTDQPADNQTLLRQNLGLAVYRRRIAAGTQLD
LGLVHDYAAVHLDGREIGHVSRMRHAHLNSATQLALPNAAAKERQLDMLVDSFGHINFGPALGDAKGLLGPVRLDGSELR
GWQVYGLALDSDTAPTLRPLQAPAARPGLFFAADIALQTVGDVYLDMRQWRKGYLWVNGRLLGRYWNVGPQQCLFCPGAW
LRKGNNAVLVLDLHQMEATAIHCADSLRAAHDAATTARSTHAAYSAC
>Mature_606_residues
PDGRPHVFGFDRGQFVLDQQPWQLRSGEMHPLRIARADWLQRIRMAKAMGLNTIALYLMWNAYEREPGQFDFATDERDFV
AFIKLCQQEGMWVYLRPGPYVCAEWTLGGLPPYLLREPGMRLRDANDARYMAAVQRYIAAVAPHLAPLMAGAGGPVLMLQ
IENEYSMHGSDVGYLQALAALWRQHGIDGPFSLAEGMKDLRRRKAYLPGAALGLDGADLQELQQARTIAGDAPVWVAEGY
PGWLTHWGDADVARRDYAPMLQHLMAAGYSFNLYVVHGGSNFGLSAGANAEDDGSQFQPVLTSYDYSAPIDERGCATPAY
TALRSIIAQHSSGPLPAIPAAPARTRFDAVIAHPVASLWDNLGDQPVPTDQPADNQTLLRQNLGLAVYRRRIAAGTQLDL
GLVHDYAAVHLDGREIGHVSRMRHAHLNSATQLALPNAAAKERQLDMLVDSFGHINFGPALGDAKGLLGPVRLDGSELRG
WQVYGLALDSDTAPTLRPLQAPAARPGLFFAADIALQTVGDVYLDMRQWRKGYLWVNGRLLGRYWNVGPQQCLFCPGAWL
RKGNNAVLVLDLHQMEATAIHCADSLRAAHDAATTARSTHAAYSAC

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI164519026, Length=598, Percent_Identity=31.1036789297659, Blast_Score=298, Evalue=7e-81,
Organism=Homo sapiens, GI31543093, Length=591, Percent_Identity=31.1336717428088, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI40255043, Length=646, Percent_Identity=31.733746130031, Blast_Score=270, Evalue=3e-72,
Organism=Homo sapiens, GI119372308, Length=603, Percent_Identity=31.6749585406302, Blast_Score=259, Evalue=7e-69,
Organism=Homo sapiens, GI119372312, Length=603, Percent_Identity=31.6749585406302, Blast_Score=258, Evalue=8e-69,
Organism=Homo sapiens, GI208022658, Length=385, Percent_Identity=29.0909090909091, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI72000600, Length=605, Percent_Identity=31.7355371900826, Blast_Score=271, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17568491, Length=608, Percent_Identity=25.8223684210526, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24646169, Length=619, Percent_Identity=30.8562197092084, Blast_Score=265, Evalue=7e-71,
Organism=Drosophila melanogaster, GI24582088, Length=620, Percent_Identity=30.3225806451613, Blast_Score=253, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 66630; Mature: 66498

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGRPHVFGFDRGQFVLDQQPWQLRSGEMHPLRIARADWLQRIRMAKAMGLNTIALYLM
CCCCCCCEEECCCCCEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHEEEEEE
WNAYEREPGQFDFATDERDFVAFIKLCQQEGMWVYLRPGPYVCAEWTLGGLPPYLLREPG
EHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCHHHHCCCC
MRLRDANDARYMAAVQRYIAAVAPHLAPLMAGAGGPVLMLQIENEYSMHGSDVGYLQALA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
ALWRQHGIDGPFSLAEGMKDLRRRKAYLPGAALGLDGADLQELQQARTIAGDAPVWVAEG
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCCCEEEECC
YPGWLTHWGDADVARRDYAPMLQHLMAAGYSFNLYVVHGGSNFGLSAGANAEDDGSQFQP
CCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCH
VLTSYDYSAPIDERGCATPAYTALRSIIAQHSSGPLPAIPAAPARTRFDAVIAHPVASLW
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DNLGDQPVPTDQPADNQTLLRQNLGLAVYRRRIAAGTQLDLGLVHDYAAVHLDGREIGHV
HHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCEEEEEECCHHHHHH
SRMRHAHLNSATQLALPNAAAKERQLDMLVDSFGHINFGPALGDAKGLLGPVRLDGSELR
HHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
GWQVYGLALDSDTAPTLRPLQAPAARPGLFFAADIALQTVGDVYLDMRQWRKGYLWVNGR
CEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCE
LLGRYWNVGPQQCLFCPGAWLRKGNNAVLVLDLHQMEATAIHCADSLRAAHDAATTARST
EEEEECCCCHHHEEECCCHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAYSAC
HHHHHCC
>Mature Secondary Structure 
PDGRPHVFGFDRGQFVLDQQPWQLRSGEMHPLRIARADWLQRIRMAKAMGLNTIALYLM
CCCCCCEEECCCCCEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHEEEEEE
WNAYEREPGQFDFATDERDFVAFIKLCQQEGMWVYLRPGPYVCAEWTLGGLPPYLLREPG
EHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCHHHHCCCC
MRLRDANDARYMAAVQRYIAAVAPHLAPLMAGAGGPVLMLQIENEYSMHGSDVGYLQALA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
ALWRQHGIDGPFSLAEGMKDLRRRKAYLPGAALGLDGADLQELQQARTIAGDAPVWVAEG
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCCCEEEECC
YPGWLTHWGDADVARRDYAPMLQHLMAAGYSFNLYVVHGGSNFGLSAGANAEDDGSQFQP
CCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCH
VLTSYDYSAPIDERGCATPAYTALRSIIAQHSSGPLPAIPAAPARTRFDAVIAHPVASLW
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DNLGDQPVPTDQPADNQTLLRQNLGLAVYRRRIAAGTQLDLGLVHDYAAVHLDGREIGHV
HHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCEEEEEECCHHHHHH
SRMRHAHLNSATQLALPNAAAKERQLDMLVDSFGHINFGPALGDAKGLLGPVRLDGSELR
HHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
GWQVYGLALDSDTAPTLRPLQAPAARPGLFFAADIALQTVGDVYLDMRQWRKGYLWVNGR
CEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCE
LLGRYWNVGPQQCLFCPGAWLRKGNNAVLVLDLHQMEATAIHCADSLRAAHDAATTARST
EEEEECCCCHHHEEECCCHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAYSAC
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]