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The map label for this gene is oxyR [H]

Identifier: 21242280

GI number: 21242280

Start: 1766099

End: 1766998

Strand: Reverse

Name: oxyR [H]

Synonym: XAC1529

Alternate gene names: 21242280

Gene position: 1766998-1766099 (Counterclockwise)

Preceding gene: 21242281

Following gene: 21242279

Centisome position: 34.14

GC content: 66.44

Gene sequence:

>900_bases
ATGCCGCGCCCCAGAACCACCCTTCGCCAGCTGAGCTATTTCGTCGCGCTGGCAGATACCGGCAGCTTTACCCGCGCCGC
CGAGCAGATGGGCGTCTCGCAGCCATCGTTGTCGCAGCAGATCCGCGCATTGGAAGCGATCATCGGCGCGCCGCTGTTCG
AGCGCGGCACGCAGGCGATCCTGACCCCGCTGGGGCGCGATCTGCTCGACCGCGCACGCAGCATCCTGCTCGATGTCAAC
GATCTGGAAGAGGTCCGCGCCACCGCCGCCGATACCTTGATCGGCACCATCCGCCTCGGCGTCTCGCCCACGCTGGGCGC
CTATCTGATGCCCAGCCTGGTGGCACGTTTGCATCGCGAGCATCCGGCCCTGCGCGTGCATGTGCGCGAAGGCCTGCCAA
CCGCACTCGCCGCCGACCTGAGCAACGGCACGCACGATCTTGTCCTCGCGCAACTGCCGGTGGCCGGCCGCGGCCTGCAC
AGCGAGCGGCTGTTTCGCGAATTGCTGCATGTGACCATGGCTGCCGATCATCCGCTGCGCACCAAGGTCTGCATCACCCC
GGCCGATCTGCGCGGCGCCAACTTGCTGACCTTGATGCCGGAATACCGATTGGCAGAACAGGTTGCCGCGATCGCCATGG
ATGTGGGCGCCAATGTCTTGCGCGATTACGAAGGCACCAGCCTGGACGCGATCCGCCAGATGGCCGGCATGGGCATGGGT
CTTGCCTTGCTCCCGGACCTGTACGTGCGCCAGGAAATCCGCGAAGGCGACGAGGTGGTGGTTCGGCCGGTCAAAGGCGG
GCGCTACTATAGGGAGATCGGTCTGCTCTGGCGCCAGGGTGCCGGTCGCGCACCGGCCTTCGGTTTGATCGCCAATCTGC
TGCGCGCGGTGGCTGCATAG

Upstream 100 bases:

>100_bases
TCGCCGGACGAGTTGCCGCTGCACTCGCTAGCCCCACTTCGCCTGTCTGGTCTCACCGGCCACGCCGGCCGTGCGCTCCC
ACGCAATCCGATGTGACCCC

Downstream 100 bases:

>100_bases
GAAAATCCTATGTGCCGAATAAGCGCCATGGCCTTGTTTGCGGGCCGGCAACTCGTCAATGCTTCACTGAACTCATCAAC
GGATATCGAATGGCGGCCAA

Product: hydrogen peroxide-inducible genes activator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPRPRTTLRQLSYFVALADTGSFTRAAEQMGVSQPSLSQQIRALEAIIGAPLFERGTQAILTPLGRDLLDRARSILLDVN
DLEEVRATAADTLIGTIRLGVSPTLGAYLMPSLVARLHREHPALRVHVREGLPTALAADLSNGTHDLVLAQLPVAGRGLH
SERLFRELLHVTMAADHPLRTKVCITPADLRGANLLTLMPEYRLAEQVAAIAMDVGANVLRDYEGTSLDAIRQMAGMGMG
LALLPDLYVRQEIREGDEVVVRPVKGGRYYREIGLLWRQGAGRAPAFGLIANLLRAVAA

Sequences:

>Translated_299_residues
MPRPRTTLRQLSYFVALADTGSFTRAAEQMGVSQPSLSQQIRALEAIIGAPLFERGTQAILTPLGRDLLDRARSILLDVN
DLEEVRATAADTLIGTIRLGVSPTLGAYLMPSLVARLHREHPALRVHVREGLPTALAADLSNGTHDLVLAQLPVAGRGLH
SERLFRELLHVTMAADHPLRTKVCITPADLRGANLLTLMPEYRLAEQVAAIAMDVGANVLRDYEGTSLDAIRQMAGMGMG
LALLPDLYVRQEIREGDEVVVRPVKGGRYYREIGLLWRQGAGRAPAFGLIANLLRAVAA
>Mature_298_residues
PRPRTTLRQLSYFVALADTGSFTRAAEQMGVSQPSLSQQIRALEAIIGAPLFERGTQAILTPLGRDLLDRARSILLDVND
LEEVRATAADTLIGTIRLGVSPTLGAYLMPSLVARLHREHPALRVHVREGLPTALAADLSNGTHDLVLAQLPVAGRGLHS
ERLFRELLHVTMAADHPLRTKVCITPADLRGANLLTLMPEYRLAEQVAAIAMDVGANVLRDYEGTSLDAIRQMAGMGMGL
ALLPDLYVRQEIREGDEVVVRPVKGGRYYREIGLLWRQGAGRAPAFGLIANLLRAVAA

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=35.3951890034364, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788887, Length=276, Percent_Identity=30.7971014492754, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI157672245, Length=227, Percent_Identity=30.8370044052863, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367136, Length=267, Percent_Identity=29.2134831460674, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789639, Length=263, Percent_Identity=29.6577946768061, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=28.6689419795222, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=296, Percent_Identity=28.3783783783784, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=23.6947791164659, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787601, Length=152, Percent_Identity=30.9210526315789, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790262, Length=292, Percent_Identity=27.7397260273973, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788748, Length=261, Percent_Identity=26.0536398467433, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=301, Percent_Identity=24.9169435215947, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=174, Percent_Identity=28.735632183908, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786401, Length=269, Percent_Identity=23.4200743494424, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693193, Length=258, Percent_Identity=24.4186046511628, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32497; Mature: 32366

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPRTTLRQLSYFVALADTGSFTRAAEQMGVSQPSLSQQIRALEAIIGAPLFERGTQAI
CCCCHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCHHHH
LTPLGRDLLDRARSILLDVNDLEEVRATAADTLIGTIRLGVSPTLGAYLMPSLVARLHRE
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
HPALRVHVREGLPTALAADLSNGTHDLVLAQLPVAGRGLHSERLFRELLHVTMAADHPLR
CCCEEEEECCCCCHHHHHHCCCCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCC
TKVCITPADLRGANLLTLMPEYRLAEQVAAIAMDVGANVLRDYEGTSLDAIRQMAGMGMG
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
LALLPDLYVRQEIREGDEVVVRPVKGGRYYREIGLLWRQGAGRAPAFGLIANLLRAVAA
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRPRTTLRQLSYFVALADTGSFTRAAEQMGVSQPSLSQQIRALEAIIGAPLFERGTQAI
CCCHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCHHHH
LTPLGRDLLDRARSILLDVNDLEEVRATAADTLIGTIRLGVSPTLGAYLMPSLVARLHRE
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
HPALRVHVREGLPTALAADLSNGTHDLVLAQLPVAGRGLHSERLFRELLHVTMAADHPLR
CCCEEEEECCCCCHHHHHHCCCCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCC
TKVCITPADLRGANLLTLMPEYRLAEQVAAIAMDVGANVLRDYEGTSLDAIRQMAGMGMG
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
LALLPDLYVRQEIREGDEVVVRPVKGGRYYREIGLLWRQGAGRAPAFGLIANLLRAVAA
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]