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The map label for this gene is acyII [H]

Identifier: 21242190

GI number: 21242190

Start: 1658259

End: 1659968

Strand: Reverse

Name: acyII [H]

Synonym: XAC1437

Alternate gene names: 21242190

Gene position: 1659968-1658259 (Counterclockwise)

Preceding gene: 21242192

Following gene: 21242189

Centisome position: 32.07

GC content: 67.43

Gene sequence:

>1710_bases
ATGCGTCAATGGCTGGGCAGGCTGCTGCTGGGAATCGGGTTGCTGGTCCTGGCGGCCAGCCTGGGACTGTATCTGTTGAT
GCGCGGCAGCTTGCCGCAGTTGGATGGCGACAGCGCGCTCAGCGGCCTGGCTGCGTCGGTCAGCGTGCAGCGCGACCGGC
TGGGCGTGGTCACCATCGATGCAGCAAACCAGCTCGATGCGATGCGTGCGCTCGGCTACGTGCATGCGCAGGAACGCTAT
TTCGAGATGGATCTGATGCGCCGCGCACCGGCCGGCGAGTTGTCCGAGCTGTTTGGCGCAAAGGCCGTGGACCTGGACAA
GCGCAACCGCGTGCATCGCCTGCGCGCGCGCGTGCAGGCCAGCCTGGATATCGCCACCGGCAGCCAGCGCACCGCATTGC
AAGCGTATACCGATGGCGTCAATGCAGGACTGGCAGCACTGCGCGTGCGGCCCTGGCCCTATCTGCTGCTGCGCCAGACA
CCGCGTGCGTGGACGCTGGACGACTCCATCCTCACCGGCCTCGCGATGTACGCAGACCTGCAGGACAGCGACAACCAGAC
CGAGCTGGCCGCCGCGCGCATCCGTGCCGTGGTGCCCCCTGCGCTGGCGGCACTGCTCGACCATCAGGGCTCCAGTTGGG
ACGCGCCGTTGTTCGGGCCGCCACAAGGCGATGCCAGCGTGCCGGATGCGGCCACGCTGGACCTACGGCGTCTACCGCAT
CCGCCTGCCGCACCACACGCGGAAACGCCGACGCCGGGCAGCAACAACTTCGCGGTAGATGGCAGCCTCACCGCCGACGG
CCGCGCCATCGTTGCCGACGACATGCACCTGGGCCTGCGCGCGCCCAATATCTGGTTCCGCGCACGGCTGCGCTATGCAG
ACAGCAATGCGCCCGAGGGCAAGGTGGATGTCACCGGATTCACCCTGCCGGGTCTGCCGGCGGTGGTCGTGGGCAGCAAC
GGGCATGTGGCTTGGGCATTTACCAACAGTTACATCGACACTGCGGATTTCGCGCGTATTCCCGCACCTACACTGGGTCA
CCCGCAAGCACTGACCAGGCACGTGGAAACCATCCGCGTGGCGGGCGCAGCGCCGGTGCAGTTCGAGGTCAGTGAAGCGG
CGTGGGGACCGGTATTGCACGTCAACGCCGACGGCAGCGCGCTGGCATTGCGCTGGGCGGCGCAGTTGCCCGGTGCGATC
CGGTTGGACTTCGCCCAGATGAGCACAGCGGGCGATCTGCAGGCAGCGTTTGCGGTGGCCGACCGCTCCGGCATTCCGGC
GCAGAACCTGCTGCTTGCCGATCGCAGCGGGCACATCGCCTGGCGCCTGATCGGCGCGCGCCCCGCGCGCAATGCCGGGT
GCGGCCCGAGCGGGATTGCCGAATTGGCGACATCGACGCCCGCACCTGAGGCAGCATCCAGCGCACCTGCAGAGGCGGCT
GCAACGCCTTCGATGTCGGGCACCTGCCTGCCATGGTCGCTGCGCAGCGATGCTGCGCCTGCGTTGATCGATCCGCCGTC
GCACCGGCTCTGGACCGCCAACAACCGTATCGTCGATGCGCAACAACTGGCCACGCTTGGCAACGCAGGTTACGACCTTG
GCGCGCGTGCGCAGCAGATTCGCGAGGATCTTTTCGCAAAGCAGCGCTTCAACGAACGCGATCTGCTCGCCATCCAGCTC
GACGATCGCGCCGTGCTGCTCACGCGCTAG

Upstream 100 bases:

>100_bases
GCAATGATCTAATCGGAATCACTTTCAGTTGCGCTTGCGGCCAGACCCGCCACGGTCATGTCCGCCGGCCACACTTTCAC
CGGGCTCCAAGGAACCGACA

Downstream 100 bases:

>100_bases
TGGCAACTGCTGCGTAGCGTGGTCGAGCACAGCAAGGACCCGGCACTGCAACAGATTGCTCACGCCACGCGCCACTGGGA
TGGGCGCGCCTCGACTGACT

Product: penicillin acylase II

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MRQWLGRLLLGIGLLVLAASLGLYLLMRGSLPQLDGDSALSGLAASVSVQRDRLGVVTIDAANQLDAMRALGYVHAQERY
FEMDLMRRAPAGELSELFGAKAVDLDKRNRVHRLRARVQASLDIATGSQRTALQAYTDGVNAGLAALRVRPWPYLLLRQT
PRAWTLDDSILTGLAMYADLQDSDNQTELAAARIRAVVPPALAALLDHQGSSWDAPLFGPPQGDASVPDAATLDLRRLPH
PPAAPHAETPTPGSNNFAVDGSLTADGRAIVADDMHLGLRAPNIWFRARLRYADSNAPEGKVDVTGFTLPGLPAVVVGSN
GHVAWAFTNSYIDTADFARIPAPTLGHPQALTRHVETIRVAGAAPVQFEVSEAAWGPVLHVNADGSALALRWAAQLPGAI
RLDFAQMSTAGDLQAAFAVADRSGIPAQNLLLADRSGHIAWRLIGARPARNAGCGPSGIAELATSTPAPEAASSAPAEAA
ATPSMSGTCLPWSLRSDAAPALIDPPSHRLWTANNRIVDAQQLATLGNAGYDLGARAQQIREDLFAKQRFNERDLLAIQL
DDRAVLLTR

Sequences:

>Translated_569_residues
MRQWLGRLLLGIGLLVLAASLGLYLLMRGSLPQLDGDSALSGLAASVSVQRDRLGVVTIDAANQLDAMRALGYVHAQERY
FEMDLMRRAPAGELSELFGAKAVDLDKRNRVHRLRARVQASLDIATGSQRTALQAYTDGVNAGLAALRVRPWPYLLLRQT
PRAWTLDDSILTGLAMYADLQDSDNQTELAAARIRAVVPPALAALLDHQGSSWDAPLFGPPQGDASVPDAATLDLRRLPH
PPAAPHAETPTPGSNNFAVDGSLTADGRAIVADDMHLGLRAPNIWFRARLRYADSNAPEGKVDVTGFTLPGLPAVVVGSN
GHVAWAFTNSYIDTADFARIPAPTLGHPQALTRHVETIRVAGAAPVQFEVSEAAWGPVLHVNADGSALALRWAAQLPGAI
RLDFAQMSTAGDLQAAFAVADRSGIPAQNLLLADRSGHIAWRLIGARPARNAGCGPSGIAELATSTPAPEAASSAPAEAA
ATPSMSGTCLPWSLRSDAAPALIDPPSHRLWTANNRIVDAQQLATLGNAGYDLGARAQQIREDLFAKQRFNERDLLAIQL
DDRAVLLTR
>Mature_569_residues
MRQWLGRLLLGIGLLVLAASLGLYLLMRGSLPQLDGDSALSGLAASVSVQRDRLGVVTIDAANQLDAMRALGYVHAQERY
FEMDLMRRAPAGELSELFGAKAVDLDKRNRVHRLRARVQASLDIATGSQRTALQAYTDGVNAGLAALRVRPWPYLLLRQT
PRAWTLDDSILTGLAMYADLQDSDNQTELAAARIRAVVPPALAALLDHQGSSWDAPLFGPPQGDASVPDAATLDLRRLPH
PPAAPHAETPTPGSNNFAVDGSLTADGRAIVADDMHLGLRAPNIWFRARLRYADSNAPEGKVDVTGFTLPGLPAVVVGSN
GHVAWAFTNSYIDTADFARIPAPTLGHPQALTRHVETIRVAGAAPVQFEVSEAAWGPVLHVNADGSALALRWAAQLPGAI
RLDFAQMSTAGDLQAAFAVADRSGIPAQNLLLADRSGHIAWRLIGARPARNAGCGPSGIAELATSTPAPEAASSAPAEAA
ATPSMSGTCLPWSLRSDAAPALIDPPSHRLWTANNRIVDAQQLATLGNAGYDLGARAQQIREDLFAKQRFNERDLLAIQL
DDRAVLLTR

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 60514; Mature: 60514

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQWLGRLLLGIGLLVLAASLGLYLLMRGSLPQLDGDSALSGLAASVSVQRDRLGVVTID
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCEEEEC
AANQLDAMRALGYVHAQERYFEMDLMRRAPAGELSELFGAKAVDLDKRNRVHRLRARVQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEECCHHHHHHHHHHHHHHH
SLDIATGSQRTALQAYTDGVNAGLAALRVRPWPYLLLRQTPRAWTLDDSILTGLAMYADL
EEEEECCCCCHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCEECCHHHHHHHHHHCCC
QDSDNQTELAAARIRAVVPPALAALLDHQGSSWDAPLFGPPQGDASVPDAATLDLRRLPH
CCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCC
PPAAPHAETPTPGSNNFAVDGSLTADGRAIVADDMHLGLRAPNIWFRARLRYADSNAPEG
CCCCCCCCCCCCCCCCEEECCEECCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCCCCC
KVDVTGFTLPGLPAVVVGSNGHVAWAFTNSYIDTADFARIPAPTLGHPQALTRHVETIRV
EEEEEEEECCCCCEEEECCCCEEEEEEECCCCCCCHHCCCCCCCCCCHHHHHHHHHHEEE
AGAAPVQFEVSEAAWGPVLHVNADGSALALRWAAQLPGAIRLDFAQMSTAGDLQAAFAVA
CCCCCEEEEECCCCCCCEEEECCCCCEEEEEEHHHCCCEEEEEHHHHCCCCCHHEEEEEC
DRSGIPAQNLLLADRSGHIAWRLIGARPARNAGCGPSGIAELATSTPAPEAASSAPAEAA
CCCCCCHHHEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHH
ATPSMSGTCLPWSLRSDAAPALIDPPSHRLWTANNRIVDAQQLATLGNAGYDLGARAQQI
CCCCCCCCEEEECCCCCCCCCEECCCCCCEEECCCCEECHHHHHHHCCCCCCCCHHHHHH
REDLFAKQRFNERDLLAIQLDDRAVLLTR
HHHHHHHHCCCCCCEEEEEECCEEEEEEC
>Mature Secondary Structure
MRQWLGRLLLGIGLLVLAASLGLYLLMRGSLPQLDGDSALSGLAASVSVQRDRLGVVTID
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCEEEEC
AANQLDAMRALGYVHAQERYFEMDLMRRAPAGELSELFGAKAVDLDKRNRVHRLRARVQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEECCHHHHHHHHHHHHHHH
SLDIATGSQRTALQAYTDGVNAGLAALRVRPWPYLLLRQTPRAWTLDDSILTGLAMYADL
EEEEECCCCCHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCEECCHHHHHHHHHHCCC
QDSDNQTELAAARIRAVVPPALAALLDHQGSSWDAPLFGPPQGDASVPDAATLDLRRLPH
CCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCC
PPAAPHAETPTPGSNNFAVDGSLTADGRAIVADDMHLGLRAPNIWFRARLRYADSNAPEG
CCCCCCCCCCCCCCCCEEECCEECCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCCCCC
KVDVTGFTLPGLPAVVVGSNGHVAWAFTNSYIDTADFARIPAPTLGHPQALTRHVETIRV
EEEEEEEECCCCCEEEECCCCEEEEEEECCCCCCCHHCCCCCCCCCCHHHHHHHHHHEEE
AGAAPVQFEVSEAAWGPVLHVNADGSALALRWAAQLPGAIRLDFAQMSTAGDLQAAFAVA
CCCCCEEEEECCCCCCCEEEECCCCCEEEEEEHHHCCCEEEEEHHHHCCCCCHHEEEEEC
DRSGIPAQNLLLADRSGHIAWRLIGARPARNAGCGPSGIAELATSTPAPEAASSAPAEAA
CCCCCCHHHEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHH
ATPSMSGTCLPWSLRSDAAPALIDPPSHRLWTANNRIVDAQQLATLGNAGYDLGARAQQI
CCCCCCCCEEEECCCCCCCCCEECCCCCCEEECCCCEECHHHHHHHCCCCCCCCHHHHHH
REDLFAKQRFNERDLLAIQLDDRAVLLTR
HHHHHHHHCCCCCCEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]