Click here to switch to the map view.

The map label for this gene is tsf

Identifier: 21242174

GI number: 21242174

Start: 1636512

End: 1637390

Strand: Reverse

Name: tsf

Synonym: XAC1421

Alternate gene names: 21242174

Gene position: 1637390-1636512 (Counterclockwise)

Preceding gene: 21242175

Following gene: 21242173

Centisome position: 31.64

GC content: 63.82

Gene sequence:

>879_bases
ATGGAAATCACTGCTTCCCTGGTCAAGGAACTGCGCGAGCGCACCGGCGCCGGCATGATGGAGTGCAAGAAGGCACTCGT
CGAAAACGCAGGCGACATCGACGCCGCGGCCGAGTGGCTGCGCAAGTCGGGCCTGGCCAAGGCCGACAAGAAGGCCGACC
GCGTTGCCGCCGAAGGCCGCATCGCCACCGCCCAGGCCGGCGGCAAGGCCGTGCTGGTCGAAGTCAACTCCGAGACCGAC
TTCGTCGCCAAGGACGAGAACTTCCTGGCCTTCACCGAGGTTGTGGCCAATGCCGCACTGAACTCGGACGCTGCCGATGC
CGAAGCGCTCAAGAGCGTCAAGCTCGACAGCGGCGAGACCATCGAAGAGCGTCGCGCTGCGGTGATCGCCAAGGTCGGCG
AAAACCTGCAGGTGCGTCGCCTGGTCCGTATCGACAGCGCCAACAACGTCGCGGCCTATGTGCACGGCGGCCGTATCGGC
GTGCTGGTCGAACTGAAGGGTGGCGACATCGAGCTGGCGCGCGGCATCGCCATGCACATCGCGGCGATGAACCCGCCGCA
CGTCAAGGCGTCCGACGTTCCGGCCGAATTCGTTGCCAAGGAAAAGGAAATCGAACTGGCCAAGATGTCCGAAAAGGACA
AGGCCAAGCCGGCCGAGATCCTGGAAAAGATCATCAGCGGCAAGATCAGCAAGATCGTCAACGAAGTAACGCTGTACGGC
CAGCCGTATGTGCTCAACACCGACCAGACCGTCGAGCAGGCAGTCAAGGCCGCCGGCGCCGAAGTGATCGGCTTCCAGCG
CCTGGCCGTTGGCGAAGGCATCGAGAAGGTGGTGGAAGACTACGCCGCCGAAGTGATGAAGCAGGCCGGCCTGGCCTGA

Upstream 100 bases:

>100_bases
GAGGCTACTGCATACATCTACGGGGGCAGCGGCATGCCGCACCGTCTCCTACTGGCGGAATCACTTCCGCCGCACGCATT
CGTCCATATGAGGTAATTCC

Downstream 100 bases:

>100_bases
TCTTCCCCGCTCGAAGGAAAGCCGCGGCATGCCGCGGCTTTTTTTTGCCTGTCGATCGCGCATCCGCACACCGGCGCGAA
CCTGAAGCGAACGCATCCGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETD
FVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIG
VLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
QPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA

Sequences:

>Translated_292_residues
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETD
FVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIG
VLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
QPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
>Mature_292_residues
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETD
FVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIG
VLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
QPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=300, Percent_Identity=28.6666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI291084500, Length=321, Percent_Identity=27.7258566978193, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI291084502, Length=94, Percent_Identity=42.5531914893617, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI291084498, Length=94, Percent_Identity=42.5531914893617, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786366, Length=284, Percent_Identity=51.056338028169, Blast_Score=256, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=26.8707482993197, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921466, Length=305, Percent_Identity=28.1967213114754, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_XANAC (Q8PMK6)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641756.1
- ProteinModelPortal:   Q8PMK6
- SMR:   Q8PMK6
- GeneID:   1155492
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1421
- NMPDR:   fig|190486.1.peg.1400
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   XAXO190486:XAC1421-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31048; Mature: 31048

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGR
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
IATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGET
EEEECCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
IEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHI
HHHHHHHHHHHHCCCCEEEHEEEECCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHE
AAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
EECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
CCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGR
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
IATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGET
EEEECCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
IEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHI
HHHHHHHHHHHHCCCCEEEHEEEECCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHE
AAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
EECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QPYVLNTDQTVEQAVKAAGAEVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
CCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217