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The map label for this gene is accA

Identifier: 21242158

GI number: 21242158

Start: 1616822

End: 1617781

Strand: Reverse

Name: accA

Synonym: XAC1405

Alternate gene names: 21242158

Gene position: 1617781-1616822 (Counterclockwise)

Preceding gene: 21242159

Following gene: 21242157

Centisome position: 31.26

GC content: 64.79

Gene sequence:

>960_bases
ATGAATCCTAACTACCTCGACTTCGAGCAACCCATCGCCGATCTGGAAGCAAAGATCCAGGAACTGCGCAAGGCCAGTAC
CGGGCCTGCGGTCAACGTGGAGACCGAAGTGCGTGCGCTGCGCGACAAGCTGCGCGTGCGCACCGCGCAGATCTTCCGCG
ATCTGTCGGCCTGGCAGGTCTCGCAGCTGGCGCGTCATCCGCAGCGCCCGTACACGCTGGACTACATCAACACCATCTGC
GACGAATTCCATGAACTGGCCGGCGACCGCGCCTACGCCGACGACAAGGCCATCGTCGGTGGCCTGGGCCGTATCGACGG
CCGCCCGGTGGTGATCATCGGGCACCAGAAGGGCCGCGATACCAAGACCAAGGTGGCACGCAACTTCGGCATGCCGCGCC
CGGAGGGCTACCGCAAGGCCTTGCGCCTGATGAAGCTGGCCGAACGCTTCCGCCTGCCGCTGCTGACCTTCATCGACACG
CCCGGCGCGTATCCGGGCATCGGTGCCGAGGAGCGCGGCCAGTCCGAGGCGATCGCGCGCAACCTGCTGGAAATGGCCGA
GCTGAAAATCCCGGTGATCTGCACCGTGATCGGCGAAGGCGGCTCCGGCGGCGCGTTGGCGATCGGCGTGGGCGACCGCA
CCCTGATGCTGGAATACGGCACCTATTCGGTGATTTCGCCGGAAGGCTGCGCCTCGATCCTGTGGAAGGACGCGGCCAAG
GCCAAGGACGCCGCCGAACAGCTCGGTCTGACCGCCAAGCGCCTGAAAGGCCTGGGCCTGGTCGACAAGGTGATCCGTGA
ACCCACCGGCGGTGCGCATCGCAATCCCGAACAGATGGGCAAGCGTCTGAAAGCGGTACTGCTCAACGAGCTGGACGCGC
TGGAAAAGATTCCAGTGGATACGTTGCTGCAGCAGCGCTACGAGCGACTGCGCAGCTATGGTGCCTACGAAGGGCATTGA

Upstream 100 bases:

>100_bases
TTCCCGATTCTCCATTCCCGATTCCGCTCCCAACGCCCCCGTACGGGCCGAAGGCAGCGCTTCAGCTACACTCCCCGCCT
TACGTTGACGACGCCATTGC

Downstream 100 bases:

>100_bases
TTCGCACGAAGGCCGGCCGCGCCAAGTGCGCGGCCATGGAAAGGACGCCACACCTGCATGTCTCCGCTCCTGCTGATCTC
ACTGCTGCTGCAAGCCGCCT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYINTIC
DEFHELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDT
PGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVDTLLQQRYERLRSYGAYEGH

Sequences:

>Translated_319_residues
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYINTIC
DEFHELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDT
PGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVDTLLQQRYERLRSYGAYEGH
>Mature_319_residues
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYINTIC
DEFHELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDT
PGAYPGIGAEERGQSEAIARNLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVDTLLQQRYERLRSYGAYEGH

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=67.5078864353312, Blast_Score=437, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_XANAC (Q8PMM1)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641740.1
- ProteinModelPortal:   Q8PMM1
- SMR:   Q8PMM1
- GeneID:   1155476
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1405
- NMPDR:   fig|190486.1.peg.1384
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   XAXO190486:XAC1405-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35271; Mature: 35271

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLARHPQRPYTLDYINTICDEFHELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCC
TKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCHHHHHHH
NLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
HHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEEEEECCEEEECCHHHHHHHHHHHHH
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVD
HHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
TLLQQRYERLRSYGAYEGH
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVETEVRALRDKLRVRTAQIFRDLSAWQV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLARHPQRPYTLDYINTICDEFHELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCC
TKTKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCHHHHHHH
NLLEMAELKIPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAK
HHHHHHHCCCCEEEEEEECCCCCCEEEEECCCEEEEEEECCEEEECCHHHHHHHHHHHHH
AKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKIPVD
HHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
TLLQQRYERLRSYGAYEGH
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217