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The map label for this gene is kdpE [H]

Identifier: 21241531

GI number: 21241531

Start: 903904

End: 904620

Strand: Direct

Name: kdpE [H]

Synonym: XAC0760

Alternate gene names: 21241531

Gene position: 903904-904620 (Clockwise)

Preceding gene: 21241530

Following gene: 21241537

Centisome position: 17.46

GC content: 66.25

Gene sequence:

>717_bases
ATGCCGACTGACCTCACTGCCATCCCGCCCGCCCGCGTGCTGATCGTCGACGACGAGCCGCAGATCCGCCGTTTCCTCGA
CATCAGCCTGCGTGCGCAGGGCTATCGTGTGCTGCAGGCCGGCACCGGCGAAGAAGGCCTGGCCTTGCTGGCCGGGCAGG
GCGCCGAACTGGTGGTGCTGGACATCGGCCTGCCCGATCGCGATGGGCATGAAGTGCTGCGCGAGATCCGCCAGTGGTCC
AACGTGCCGGTGATCATGCTCACCGTACGCGCCGGCGAAACCGAAAAGGTCGCCGCGCTCGATGCCGGCGCCAACGACTA
CGTCACCAAACCCTTCGGCGTGCAGGAATTGATGGCCCGCATCCGCTCGCTGCTGCGCCAGGCCGGCGCCGGCAGCACGG
TGGAAGAAAGCGTGTTCGACGACGGCCGCCTGCATATCCATCTGGGCCTGCGCGAGGTCACCCTCGATGGCGAAGCGGTG
CCCTTGAGCCGCAAGGAATACGCCTTGCTCGCGCTGTTGCTCAAGCACGCCGGCCGTGTGGTCACCCAGCCGCAACTGCT
GCGTGAGGTGTGGGGCCCCACCCACGAGGAAGACACCCATTATCTGCGCATCCTGGTCGGCAAATTGCGCCAGAAACTGC
ACGACGATGCCGCCGACCCGCACTACATCGTCACCGAGCCCGGCGTGGGTCTGCGGTTTATCGGGGTAATGCGTTGA

Upstream 100 bases:

>100_bases
CACGGCGGCAGCGTGGCGGCATTGGCGGGCGCGCATGGTCACGGCACCACCATCCGCATTACGCTGCCGTTGCTCGTTCC
CGCCGCGCCACCTCGCCCCG

Downstream 100 bases:

>100_bases
GCTCGATCGCCTGCAGGTTGGGTCACCTTCATTCGGTAGGAGTGCACCCGCCTGGCAAGTGGTTGAGAACGGATTGGCGA
GCAACTTGGGAACACCAGAC

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MPTDLTAIPPARVLIVDDEPQIRRFLDISLRAQGYRVLQAGTGEEGLALLAGQGAELVVLDIGLPDRDGHEVLREIRQWS
NVPVIMLTVRAGETEKVAALDAGANDYVTKPFGVQELMARIRSLLRQAGAGSTVEESVFDDGRLHIHLGLREVTLDGEAV
PLSRKEYALLALLLKHAGRVVTQPQLLREVWGPTHEEDTHYLRILVGKLRQKLHDDAADPHYIVTEPGVGLRFIGVMR

Sequences:

>Translated_238_residues
MPTDLTAIPPARVLIVDDEPQIRRFLDISLRAQGYRVLQAGTGEEGLALLAGQGAELVVLDIGLPDRDGHEVLREIRQWS
NVPVIMLTVRAGETEKVAALDAGANDYVTKPFGVQELMARIRSLLRQAGAGSTVEESVFDDGRLHIHLGLREVTLDGEAV
PLSRKEYALLALLLKHAGRVVTQPQLLREVWGPTHEEDTHYLRILVGKLRQKLHDDAADPHYIVTEPGVGLRFIGVMR
>Mature_237_residues
PTDLTAIPPARVLIVDDEPQIRRFLDISLRAQGYRVLQAGTGEEGLALLAGQGAELVVLDIGLPDRDGHEVLREIRQWSN
VPVIMLTVRAGETEKVAALDAGANDYVTKPFGVQELMARIRSLLRQAGAGSTVEESVFDDGRLHIHLGLREVTLDGEAVP
LSRKEYALLALLLKHAGRVVTQPQLLREVWGPTHEEDTHYLRILVGKLRQKLHDDAADPHYIVTEPGVGLRFIGVMR

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=49.0990990990991, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=34.1880341880342, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=35, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=32.5688073394495, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=37.9310344827586, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=31.7391304347826, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=28.9473684210526, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=29.8245614035088, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=211, Percent_Identity=33.6492890995261, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=32.7272727272727, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=30.6666666666667, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=32.4561403508772, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=41.2280701754386, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=26.2931034482759, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=33.6065573770492, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=33.0645161290323, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=34, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26276; Mature: 26144

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDLTAIPPARVLIVDDEPQIRRFLDISLRAQGYRVLQAGTGEEGLALLAGQGAELVVL
CCCCCCCCCCEEEEEECCCHHHHHHHHHEEECCCEEEEECCCCCCCEEEEECCCCEEEEE
DIGLPDRDGHEVLREIRQWSNVPVIMLTVRAGETEKVAALDAGANDYVTKPFGVQELMAR
ECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHH
IRSLLRQAGAGSTVEESVFDDGRLHIHLGLREVTLDGEAVPLSRKEYALLALLLKHAGRV
HHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
VTQPQLLREVWGPTHEEDTHYLRILVGKLRQKLHDDAADPHYIVTEPGVGLRFIGVMR
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECC
>Mature Secondary Structure 
PTDLTAIPPARVLIVDDEPQIRRFLDISLRAQGYRVLQAGTGEEGLALLAGQGAELVVL
CCCCCCCCCEEEEEECCCHHHHHHHHHEEECCCEEEEECCCCCCCEEEEECCCCEEEEE
DIGLPDRDGHEVLREIRQWSNVPVIMLTVRAGETEKVAALDAGANDYVTKPFGVQELMAR
ECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHH
IRSLLRQAGAGSTVEESVFDDGRLHIHLGLREVTLDGEAVPLSRKEYALLALLLKHAGRV
HHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
VTQPQLLREVWGPTHEEDTHYLRILVGKLRQKLHDDAADPHYIVTEPGVGLRFIGVMR
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]