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The map label for this gene is ddlA [H]

Identifier: 21241014

GI number: 21241014

Start: 288478

End: 288705

Strand: Reverse

Name: ddlA [H]

Synonym: XAC0240

Alternate gene names: 21241014

Gene position: 288705-288478 (Counterclockwise)

Preceding gene: 21241019

Following gene: 21241010

Centisome position: 5.58

GC content: 62.28

Gene sequence:

>228_bases
ATGCGCACGATTCGGGTCGGCCTCATCTTCGGAGGCAAATCGGCCGAGCACGAGGTCTCGTTGCAATCGGCGCGCGATAT
CCTGGATGCGCTGGACCCGCGACGCTTCGAGCCGGTGCTGATCGGTATCGATTGCTCGCGCTGGACCAGGACGCGCGTCA
TGCCACTGCGAATTTCGGGGGGATGGCCGATCGCTTTGCACGGGTTGTGTATGTCGATCGCATCGTGA

Upstream 100 bases:

>100_bases
CGGGCATGCCGGCGTTGTTCGCCAGCACTGTCTGCGGCAAGACGTCCTTCAGCGCATACGCCACAGGCATCCTGTCCACT
TCCAATGGCAGGAGCAGGCA

Downstream 100 bases:

>100_bases
TGGCGCGCATGCACGTCGGCGCGATCTGCTACGCAGCTGCATGACGAACTCATCCGTCAGCCACATGCAGTAAGACAGCG
GCGGCTGGTGTGCGAGGTCA

Product: D-alanine-D-alanine ligase

Products: NA

Alternate protein names: D-Ala-D-Ala ligase A; D-alanylalanine synthetase A [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MRTIRVGLIFGGKSAEHEVSLQSARDILDALDPRRFEPVLIGIDCSRWTRTRVMPLRISGGWPIALHGLCMSIAS

Sequences:

>Translated_75_residues
MRTIRVGLIFGGKSAEHEVSLQSARDILDALDPRRFEPVLIGIDCSRWTRTRVMPLRISGGWPIALHGLCMSIAS
>Mature_75_residues
MRTIRVGLIFGGKSAEHEVSLQSARDILDALDPRRFEPVLIGIDCSRWTRTRVMPLRISGGWPIALHGLCMSIAS

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786579, Length=44, Percent_Identity=68.1818181818182, Blast_Score=70, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 8332; Mature: 8332

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIRVGLIFGGKSAEHEVSLQSARDILDALDPRRFEPVLIGIDCSRWTRTRVMPLRISG
CCEEEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEECC
GWPIALHGLCMSIAS
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTIRVGLIFGGKSAEHEVSLQSARDILDALDPRRFEPVLIGIDCSRWTRTRVMPLRISG
CCEEEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEECC
GWPIALHGLCMSIAS
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]