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The map label for this gene is glmU [H]

Identifier: 57237662

GI number: 57237662

Start: 846755

End: 848044

Strand: Direct

Name: glmU [H]

Synonym: CJE0908

Alternate gene names: 57237662

Gene position: 846755-848044 (Clockwise)

Preceding gene: 57237660

Following gene: 57237663

Centisome position: 47.63

GC content: 32.64

Gene sequence:

>1290_bases
ATGAAAACTTCTATTTTGATTTTAGCGGCAGGATTAGGCACTAGAATGAAATCACAAAAGCCAAAGGTTTTGCAAGAGCT
TTGTCAAAAAAGTATGATTTTACACATTTTAAAAAAGGCTTTTGCTTTAAGTGATGATGTAAGTGTAGTTTTATCGCATC
AAAAAGAACGCGTTGAAAAAGAAATTTTAGAATATTTTCCAAAAACACAAATTTTAGAGCAAGACTTGCAAAATTATCCA
GGAACTGCGGGAGCTTTAAGGGGGTTTGAGCCTAAAAATGAAAGAGTGTTGATTCTTTGTGGCGATATGCCTTTGGTTGA
GCAAACAAGTTTGGAAGCTTTGTTGAGTAATAATGCAAAATTAAATCTAGCAGTTTTTAAAGCAAGAGATCCTAAAAGTT
ATGGCAGAGTGGTGATAAAAAACGATAGCGTTGAAAAAATTGTTGAATTTAAAGATGCAAATACACAAGAAAAAGAGATA
AATACTTGCAATGCTGGGGTTTATGTGATTGACTCTAGGCTTTTAAAAGAGCTTTTACCTTTGATTGATAACAATAATGC
GGCAAAAGAGTATTATTTAACCGACATTGTAAAACTAGCAAAAGAAAAAGATGTGATGATTAAAGCGGTTTTTGTAGATG
AAGATGAATTTATGGGGATTAATGATAAATTTGAACTCAGTATAGCTGAAAATTTCATGCAAGAAAAAATTAAAAAATAC
TGGATGCAACAGGGTGTGATTTTTCATTTACCGCAAAGCACTTTTATAGGTGCAGATGTTGAATTTGTAGGTGAATGTGA
AGTATATGAAAATGTAAGGATAGAGGGCAAAAGTAAGATTATAAACTCTATCATTAAAAGTTCAAGCGTGATAGAAAATT
CCATCGTAGAAAATAGCGATGTAGGGCCTTTGGCACATTTGCGTCCAAATTGTGAGTTAAAAAACACTCATATAGGAAAT
TTTGTAGAATGCAAAAATGCAAAGTTAAATACCGTAAAAGCAGGGCATTTGAGCTATTTAGGAGATTGTGAGATAGATAG
TGGAACCAATATAGGCTGTGGGACTATCACTTGTAATTATGATGGGGTAAAAAAGTATAAAACCATCATAGGAAAAAATG
TTTTTGTAGGTTCGGATACGCAATTTATCGCACCTGTAAAAATCGAAGATGAAGTGATCATAGCAGCAGGAAGCACAGTA
AGTGTCAATGTAGAAAAGGGTGCTTTGTTTATCAATAGAGCAGGGCATAAAATGATAAAAGATTATTATTATAAGAAATT
TCAAAAATGA

Upstream 100 bases:

>100_bases
TTTTATCTTTTGATGACTAAAAACTAGTTTAAGGGTATTAGGATTTTAACTTTAAACTGCTAAAATAGTCTTTTAGACTT
CTTAATAACAAAGGTAAAAA

Downstream 100 bases:

>100_bases
AAACCATACTTTTAGCCATTAGCGGTAGTATAGCTTTTTATAAATCTTATGAGCTTATTTCTTTGTTTAAAAAAGAAGGC
TTTAGGGTAAAAGTTTTGCT

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKTSILILAAGLGTRMKSQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEKEILEYFPKTQILEQDLQNYP
GTAGALRGFEPKNERVLILCGDMPLVEQTSLEALLSNNAKLNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEI
NTCNAGVYVIDSRLLKELLPLIDNNNAAKEYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQEKIKKY
WMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENSIVENSDVGPLAHLRPNCELKNTHIGN
FVECKNAKLNTVKAGHLSYLGDCEIDSGTNIGCGTITCNYDGVKKYKTIIGKNVFVGSDTQFIAPVKIEDEVIIAAGSTV
SVNVEKGALFINRAGHKMIKDYYYKKFQK

Sequences:

>Translated_429_residues
MKTSILILAAGLGTRMKSQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEKEILEYFPKTQILEQDLQNYP
GTAGALRGFEPKNERVLILCGDMPLVEQTSLEALLSNNAKLNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEI
NTCNAGVYVIDSRLLKELLPLIDNNNAAKEYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQEKIKKY
WMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENSIVENSDVGPLAHLRPNCELKNTHIGN
FVECKNAKLNTVKAGHLSYLGDCEIDSGTNIGCGTITCNYDGVKKYKTIIGKNVFVGSDTQFIAPVKIEDEVIIAAGSTV
SVNVEKGALFINRAGHKMIKDYYYKKFQK
>Mature_429_residues
MKTSILILAAGLGTRMKSQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEKEILEYFPKTQILEQDLQNYP
GTAGALRGFEPKNERVLILCGDMPLVEQTSLEALLSNNAKLNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEI
NTCNAGVYVIDSRLLKELLPLIDNNNAAKEYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQEKIKKY
WMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENSIVENSDVGPLAHLRPNCELKNTHIGN
FVECKNAKLNTVKAGHLSYLGDCEIDSGTNIGCGTITCNYDGVKKYKTIIGKNVFVGSDTQFIAPVKIEDEVIIAAGSTV
SVNVEKGALFINRAGHKMIKDYYYKKFQK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=442, Percent_Identity=37.7828054298643, Blast_Score=261, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 48037; Mature: 48037

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSILILAAGLGTRMKSQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEK
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EILEYFPKTQILEQDLQNYPGTAGALRGFEPKNERVLILCGDMPLVEQTSLEALLSNNAK
HHHHHCCCHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCE
LNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEINTCNAGVYVIDSRLLKELLP
EEEEEEECCCCHHHCEEEEECCCHHHHHHHCCCCCCHHHCCCCCCCEEEECHHHHHHHHH
LIDNNNAAKEYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQEKIKKY
HHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHCCCCCCCEEHHHHHHHHHHHHHHH
WMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENSIVENSD
HHHCCEEEECCCCCEECCCCEEEECEEEECCEEECCHHHHHHHHHHHHHHHHHHHCCCCC
VGPLAHLRPNCELKNTHIGNFVECKNAKLNTVKAGHLSYLGDCEIDSGTNIGCGTITCNY
CCCHHHCCCCCCCCCCCCCCEEEECCCEECEEECCCCCEEECCCCCCCCCCCCEEEEECC
DGVKKYKTIIGKNVFVGSDTQFIAPVKIEDEVIIAAGSTVSVNVEKGALFINRAGHKMIK
CCHHHHHHHHCCCEEECCCCCEEEEEEECCCEEEEECCEEEEEEECCEEEEECCCHHHHH
DYYYKKFQK
HHHHHHHCC
>Mature Secondary Structure
MKTSILILAAGLGTRMKSQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEK
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EILEYFPKTQILEQDLQNYPGTAGALRGFEPKNERVLILCGDMPLVEQTSLEALLSNNAK
HHHHHCCCHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCE
LNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEINTCNAGVYVIDSRLLKELLP
EEEEEEECCCCHHHCEEEEECCCHHHHHHHCCCCCCHHHCCCCCCCEEEECHHHHHHHHH
LIDNNNAAKEYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQEKIKKY
HHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHCCCCCCCEEHHHHHHHHHHHHHHH
WMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENSIVENSD
HHHCCEEEECCCCCEECCCCEEEECEEEECCEEECCHHHHHHHHHHHHHHHHHHHCCCCC
VGPLAHLRPNCELKNTHIGNFVECKNAKLNTVKAGHLSYLGDCEIDSGTNIGCGTITCNY
CCCHHHCCCCCCCCCCCCCCEEEECCCEECEEECCCCCEEECCCCCCCCCCCCEEEEECC
DGVKKYKTIIGKNVFVGSDTQFIAPVKIEDEVIIAAGSTVSVNVEKGALFINRAGHKMIK
CCHHHHHHHHCCCEEECCCCCEEEEEEECCCEEEEECCEEEEEEECCEEEEECCCHHHHH
DYYYKKFQK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA