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The map label for this gene is 21226610

Identifier: 21226610

GI number: 21226610

Start: 631617

End: 632309

Strand: Reverse

Name: 21226610

Synonym: MM_0508

Alternate gene names: NA

Gene position: 632309-631617 (Counterclockwise)

Preceding gene: 21226611

Following gene: 21226609

Centisome position: 15.44

GC content: 48.05

Gene sequence:

>693_bases
TTGCAATTTTATATTATCATGAAATTCGATCTTCACGTACATTCCGAGCATTCAAAGGATAGCAATTCAAGCCACAGGGA
CATTATTGAGGTTGCCCGCAGACGGGGGCTCGACGGGTTTGCTATCTGTGACCACGACACTGTGGAAGGCGGCCTCGCCT
GCGCGGAAAAAGCCCTTGAACTCGGCCTTGAAATTACAGTACTCCCTGGGGTGGAAGTGAGTTCTTCAAAAGGGCATATT
CTGGTTCTGGGAGTAAAGGAAAATATCGAGCCCCTGCTTAGCCCGGAAGAAACAATCCTGAAGGCAAGGAAACTTGGCGG
CACAGTTATTATCCCCCACCCATTCAAACGCAGTTCCCACGGGATAGGAAGTTTCGAAGGGCTTGATATTGATGCGGTTG
AGGTCTTCAATTCTCGCTGTCTTTTTAACTCGGCCAACAGGAAAGCCCTGGAAGAAGCAAAAAGGCTCGGAATACCCGGA
GTGGCCGGGAGTGATTCCCATATTCCCGAGATGGTGGGGCAGGCATATACTGAAATCGACGCTGAAGAGAATACGGTTGA
AGCAGTACTGAAGGCTATCAGGGAAGGGAAAGTCGCCCCTGCAGGGAAAAACACTCCAACTTCAATTATCCTTGAACAGA
TGTCAGGAAGCGCAAAAAGGAAAATAAAGAGAAAGTTATTCGGAAAATCTTAA

Upstream 100 bases:

>100_bases
ATTATTTTACCACTTTTTTCCTGTTCTATTATAAGCAGGAGATTTTACATACGTCTGGTTTCTTTTTTCTTTTCCCCTTC
AAAATTTATATAAATTCTAC

Downstream 100 bases:

>100_bases
AAAACGACTGGAACTATTAATTTTTTAGATAGTATTAACTGTTCTAATATTGCTTGATTTTCCTTTATTTTTACCCTTAT
CTGTTTTTTCTAGATTTTTC

Product: isoleucyl-tRNA synthetase

Products: AMP; diphosphate; L-isoleucyl-tRNA(Ile)

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MQFYIIMKFDLHVHSEHSKDSNSSHRDIIEVARRRGLDGFAICDHDTVEGGLACAEKALELGLEITVLPGVEVSSSKGHI
LVLGVKENIEPLLSPEETILKARKLGGTVIIPHPFKRSSHGIGSFEGLDIDAVEVFNSRCLFNSANRKALEEAKRLGIPG
VAGSDSHIPEMVGQAYTEIDAEENTVEAVLKAIREGKVAPAGKNTPTSIILEQMSGSAKRKIKRKLFGKS

Sequences:

>Translated_230_residues
MQFYIIMKFDLHVHSEHSKDSNSSHRDIIEVARRRGLDGFAICDHDTVEGGLACAEKALELGLEITVLPGVEVSSSKGHI
LVLGVKENIEPLLSPEETILKARKLGGTVIIPHPFKRSSHGIGSFEGLDIDAVEVFNSRCLFNSANRKALEEAKRLGIPG
VAGSDSHIPEMVGQAYTEIDAEENTVEAVLKAIREGKVAPAGKNTPTSIILEQMSGSAKRKIKRKLFGKS
>Mature_230_residues
MQFYIIMKFDLHVHSEHSKDSNSSHRDIIEVARRRGLDGFAICDHDTVEGGLACAEKALELGLEITVLPGVEVSSSKGHI
LVLGVKENIEPLLSPEETILKARKLGGTVIIPHPFKRSSHGIGSFEGLDIDAVEVFNSRCLFNSANRKALEEAKRLGIPG
VAGSDSHIPEMVGQAYTEIDAEENTVEAVLKAIREGKVAPAGKNTPTSIILEQMSGSAKRKIKRKLFGKS

Specific function: Unknown

COG id: COG0613

COG function: function code R; Predicted metal-dependent phosphoesterases (PHP family)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0417 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: 6.1.1.5

Molecular weight: Translated: 24961; Mature: 24961

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFYIIMKFDLHVHSEHSKDSNSSHRDIIEVARRRGLDGFAICDHDTVEGGLACAEKALE
CEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
LGLEITVLPGVEVSSSKGHILVLGVKENIEPLLSPEETILKARKLGGTVIIPHPFKRSSH
CCCEEEEECCCEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCC
GIGSFEGLDIDAVEVFNSRCLFNSANRKALEEAKRLGIPGVAGSDSHIPEMVGQAYTEID
CCCCCCCCCCHHHHHHCCHHEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
AEENTVEAVLKAIREGKVAPAGKNTPTSIILEQMSGSAKRKIKRKLFGKS
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQFYIIMKFDLHVHSEHSKDSNSSHRDIIEVARRRGLDGFAICDHDTVEGGLACAEKALE
CEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
LGLEITVLPGVEVSSSKGHILVLGVKENIEPLLSPEETILKARKLGGTVIIPHPFKRSSH
CCCEEEEECCCEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCC
GIGSFEGLDIDAVEVFNSRCLFNSANRKALEEAKRLGIPGVAGSDSHIPEMVGQAYTEID
CCCCCCCCCCHHHHHHCCHHEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
AEENTVEAVLKAIREGKVAPAGKNTPTSIILEQMSGSAKRKIKRKLFGKS
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-isoleucine; tRNA(Ile)

Specific reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]