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The map label for this gene is pfkC [H]

Identifier: 21226575

GI number: 21226575

Start: 597332

End: 598807

Strand: Reverse

Name: pfkC [H]

Synonym: MM_0473

Alternate gene names: 21226575

Gene position: 598807-597332 (Counterclockwise)

Preceding gene: 21226576

Following gene: 21226574

Centisome position: 14.62

GC content: 47.63

Gene sequence:

>1476_bases
GTGGACATGGAAGAATGGGAACAGCGCCATAATGAAGCATTTTACGATGCTAAAGAAGCCCTTCCTTATCTGGACGGGAT
GTTTGTAGCTTACAACAGCAATATTGATGCTATCAGGCACCTGGATGAAGAAGCCCTGACAAAGCTTATCGGGTTTTTCG
ATGAGGCTGAAATTCAGGAAAGGGTTGCGGTATACCCGAGAGAAATTGCCGATCCGTTGGATTTCATCGCCCGCCTGCTC
ATAGCTATGAGGGAAGGGAAAGCCGCAGAAGTGCCCACATATACCGAAGAAATCCATACGTGGCTGAAAGAACACCTTGG
TTTCGACTATGCCAGAATGGGAGGCCAGGCAGGAATTATTTCAAACCTTCTTGCCCGGTTAGACCTGAAAAAGGTTGTGG
CTTATATTCCCTGGCTTTCAGCAGAGCAGGCAGAATATTTTGAAGATAACGGCAACATCCTTCACCCTAAAGTAGAAAAT
GGAGAAGTCGTCCTCAAGACTCCTGCAGAGGCTTTCAATCCCGGGATGGGGTCAAAGGTCAACTGGATATTTGAGTTTTC
CAAAGACCTCAAAGTGTCCTGCGCAGGGAGCACTTTCAAAGTGCCCAGGGACAACCGCCTGATTATCTCTTCCCGCCCCA
AATGGATCCGCCTTGATATGGACAGAGCGATATATGACCAGCTTGAGACCATCTTTCCGGTTGACGGGGCAATGCTTTCC
GGTTATCAGATGATAAAAGAAGAATATGAGGACGGGTCTACCTACAAAGATTATGTTGAGCATTCCGTAGAAGTCATTAA
TAAGCTGAAGTCATTGAACCCTGACCTCCGTATCCATGTGGAGCTCACTTCCATCCAGAACCGGGTTATAAGAAAGGCAA
TCCTTACAGAAATTGTTGCAAGGCATGTCCATTCTCTCGGGCTTGACACTGTAGAAGTTGCAAATGCTCTTAATGTACTC
GGATATGAGGAGCTTTCATATTCCGTGATCCGGAAGGGAGAAAACGGGATTATGTCCCTTTACCAGGGGGCTGTCCAGTT
AATGAAGGACCTTAAACTTGAAAGGGTACATGTTCACTCTCTTGGCTTCTATATATGCATCCTGGCAAAAGGCCACCCTC
TAACCCTGAAAGAACACAGGGATGCCCTGCTCTTCTCCTCTGTCCTCGCAGCTTCCCGGGCCCTTCACGGAAAAATCGAA
GACCTTAATGAAGCCGAAACCGGCCTGGACGTGCCTGTCTCAGCCCAGGGCCTGGAAGATCTGGAGACCTTCAAGCTTTA
CTGTACAGGAAGAAAGCTATGCAGCCCGGATGAATTTGAATACGGGTACATATACGGGTCAGATCATGACGCTATCCTCA
TACCATCCAAAGTGGTGGACAGGCCAAAAGCAACGGTAGGAATAGGAGATACCATTTCCGCAGGGGCTTTTGCAGCCATG
CTTGCAAGGATGAAACAGATAAAATCAGGGAAATAA

Upstream 100 bases:

>100_bases
CAAAACCAGGGATTTATCCTGGTTTATTTATTTCATTATTCCAGAATAATATGTTTCTTGATTCTGGATACTTTATTTTA
TTCCCAGGGGGTTTACTGAC

Downstream 100 bases:

>100_bases
GTTATGTTATAAATTTCCAGAAATTTCTGAGAAGAGACTTTTCTGGAAATTATTTTCCGGATAGGTTTTCCAGGGTAGAT
TCTTATCTTCCACGCTTTAT

Product: ADP-specific phosphofructokinase

Products: NA

Alternate protein names: ADP-dependent phosphofructokinase; ADP-Pfk [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MDMEEWEQRHNEAFYDAKEALPYLDGMFVAYNSNIDAIRHLDEEALTKLIGFFDEAEIQERVAVYPREIADPLDFIARLL
IAMREGKAAEVPTYTEEIHTWLKEHLGFDYARMGGQAGIISNLLARLDLKKVVAYIPWLSAEQAEYFEDNGNILHPKVEN
GEVVLKTPAEAFNPGMGSKVNWIFEFSKDLKVSCAGSTFKVPRDNRLIISSRPKWIRLDMDRAIYDQLETIFPVDGAMLS
GYQMIKEEYEDGSTYKDYVEHSVEVINKLKSLNPDLRIHVELTSIQNRVIRKAILTEIVARHVHSLGLDTVEVANALNVL
GYEELSYSVIRKGENGIMSLYQGAVQLMKDLKLERVHVHSLGFYICILAKGHPLTLKEHRDALLFSSVLAASRALHGKIE
DLNEAETGLDVPVSAQGLEDLETFKLYCTGRKLCSPDEFEYGYIYGSDHDAILIPSKVVDRPKATVGIGDTISAGAFAAM
LARMKQIKSGK

Sequences:

>Translated_491_residues
MDMEEWEQRHNEAFYDAKEALPYLDGMFVAYNSNIDAIRHLDEEALTKLIGFFDEAEIQERVAVYPREIADPLDFIARLL
IAMREGKAAEVPTYTEEIHTWLKEHLGFDYARMGGQAGIISNLLARLDLKKVVAYIPWLSAEQAEYFEDNGNILHPKVEN
GEVVLKTPAEAFNPGMGSKVNWIFEFSKDLKVSCAGSTFKVPRDNRLIISSRPKWIRLDMDRAIYDQLETIFPVDGAMLS
GYQMIKEEYEDGSTYKDYVEHSVEVINKLKSLNPDLRIHVELTSIQNRVIRKAILTEIVARHVHSLGLDTVEVANALNVL
GYEELSYSVIRKGENGIMSLYQGAVQLMKDLKLERVHVHSLGFYICILAKGHPLTLKEHRDALLFSSVLAASRALHGKIE
DLNEAETGLDVPVSAQGLEDLETFKLYCTGRKLCSPDEFEYGYIYGSDHDAILIPSKVVDRPKATVGIGDTISAGAFAAM
LARMKQIKSGK
>Mature_491_residues
MDMEEWEQRHNEAFYDAKEALPYLDGMFVAYNSNIDAIRHLDEEALTKLIGFFDEAEIQERVAVYPREIADPLDFIARLL
IAMREGKAAEVPTYTEEIHTWLKEHLGFDYARMGGQAGIISNLLARLDLKKVVAYIPWLSAEQAEYFEDNGNILHPKVEN
GEVVLKTPAEAFNPGMGSKVNWIFEFSKDLKVSCAGSTFKVPRDNRLIISSRPKWIRLDMDRAIYDQLETIFPVDGAMLS
GYQMIKEEYEDGSTYKDYVEHSVEVINKLKSLNPDLRIHVELTSIQNRVIRKAILTEIVARHVHSLGLDTVEVANALNVL
GYEELSYSVIRKGENGIMSLYQGAVQLMKDLKLERVHVHSLGFYICILAKGHPLTLKEHRDALLFSSVLAASRALHGKIE
DLNEAETGLDVPVSAQGLEDLETFKLYCTGRKLCSPDEFEYGYIYGSDHDAILIPSKVVDRPKATVGIGDTISAGAFAAM
LARMKQIKSGK

Specific function: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor [H]

COG id: COG4809

COG function: function code G; Archaeal ADP-dependent phosphofructokinase/glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ADPK (ADP-dependent kinase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007666
- InterPro:   IPR015990
- InterPro:   IPR011790 [H]

Pfam domain/function: PF04587 ADP_PFK_GK [H]

EC number: =2.7.1.146 [H]

Molecular weight: Translated: 55293; Mature: 55293

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMEEWEQRHNEAFYDAKEALPYLDGMFVAYNSNIDAIRHLDEEALTKLIGFFDEAEIQE
CCHHHHHHHHHHHHHHHHHHCHHHCCEEEEECCCHHHHHHCCHHHHHHHHHHCCHHHHHH
RVAVYPREIADPLDFIARLLIAMREGKAAEVPTYTEEIHTWLKEHLGFDYARMGGQAGII
HHHHCCHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHH
SNLLARLDLKKVVAYIPWLSAEQAEYFEDNGNILHPKVENGEVVLKTPAEAFNPGMGSKV
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCEEEECCHHHHCCCCCCCE
NWIFEFSKDLKVSCAGSTFKVPRDNRLIISSRPKWIRLDMDRAIYDQLETIFPVDGAMLS
EEEEEECCCCEEEECCCEEECCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCCHHHH
GYQMIKEEYEDGSTYKDYVEHSVEVINKLKSLNPDLRIHVELTSIQNRVIRKAILTEIVA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
RHVHSLGLDTVEVANALNVLGYEELSYSVIRKGENGIMSLYQGAVQLMKDLKLERVHVHS
HHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHEEHHH
LGFYICILAKGHPLTLKEHRDALLFSSVLAASRALHGKIEDLNEAETGLDVPVSAQGLED
CCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCCHH
LETFKLYCTGRKLCSPDEFEYGYIYGSDHDAILIPSKVVDRPKATVGIGDTISAGAFAAM
HHHEEEEECCCCCCCCCCCCEEEEEECCCCEEEECHHHHCCCCCEECCCCCCHHHHHHHH
LARMKQIKSGK
HHHHHHHCCCC
>Mature Secondary Structure
MDMEEWEQRHNEAFYDAKEALPYLDGMFVAYNSNIDAIRHLDEEALTKLIGFFDEAEIQE
CCHHHHHHHHHHHHHHHHHHCHHHCCEEEEECCCHHHHHHCCHHHHHHHHHHCCHHHHHH
RVAVYPREIADPLDFIARLLIAMREGKAAEVPTYTEEIHTWLKEHLGFDYARMGGQAGII
HHHHCCHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHH
SNLLARLDLKKVVAYIPWLSAEQAEYFEDNGNILHPKVENGEVVLKTPAEAFNPGMGSKV
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCEEEECCHHHHCCCCCCCE
NWIFEFSKDLKVSCAGSTFKVPRDNRLIISSRPKWIRLDMDRAIYDQLETIFPVDGAMLS
EEEEEECCCCEEEECCCEEECCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCCHHHH
GYQMIKEEYEDGSTYKDYVEHSVEVINKLKSLNPDLRIHVELTSIQNRVIRKAILTEIVA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
RHVHSLGLDTVEVANALNVLGYEELSYSVIRKGENGIMSLYQGAVQLMKDLKLERVHVHS
HHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHEEHHH
LGFYICILAKGHPLTLKEHRDALLFSSVLAASRALHGKIEDLNEAETGLDVPVSAQGLED
CCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCCCCCCHH
LETFKLYCTGRKLCSPDEFEYGYIYGSDHDAILIPSKVVDRPKATVGIGDTISAGAFAAM
HHHEEEEECCCCCCCCCCCCEEEEEECCCCEEEECHHHHCCCCCEECCCCCCHHHHHHHH
LARMKQIKSGK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]