Click here to switch to the map view.

The map label for this gene is trkA [H]

Identifier: 21226396

GI number: 21226396

Start: 393471

End: 395261

Strand: Reverse

Name: trkA [H]

Synonym: MM_0294

Alternate gene names: 21226396

Gene position: 395261-393471 (Counterclockwise)

Preceding gene: 21226397

Following gene: 21226395

Centisome position: 9.65

GC content: 45.56

Gene sequence:

>1791_bases
ATGTCTCTTGCCGCAAGGGCACTCAGTTACTATTTTCGGCTCCCTTTTATCATTTTTCTGCTGATCGAAGGAATTATTGC
CGGGCCCGAAGTCCTCAATCTGCTTGACCCTTCACTCTATATCGAAGGGCTGAGCGCCATTGTGGCAATCTCAATATCCG
TGATTGTTTTTGATGGAGGGCTCCATATTGACCTTAAGCATATAAGGATGGTTCAGGAAAGTGTCCTCAAACTGACAACA
ATAGGGGTCCTTGTGACCTTTCTGGGGACCACAGCCCTGACCAGTATTCTGATAGATATCCCTCTTGAAATTGCAGCCCT
ATTCGGAGCCCTCGTCACTGCAACAGGACCCACAGTGATAACTCCTATTGTCAGAAATATCCAGATTAGCCACAGGCTTG
GTAAAATTCTTGAACTTGAGGGGGTGCTGAATGATGCTGCAAGTGTAATCCTTGCTGCCATGGTCTTTGAATGGGTTGCA
GCAGAACTTTCCGGGACTGATGCTGTAATCTTTATTTTTTACAGGTTAGGGATAGGAATTGCGCTGGGGTCTTTGAGCGG
GTTTGCCCTCAGATGGTTTTTCACCCGGAAGATAGCGTTCAGCAAGCAGACTGTAAGGCTGGTTTCCCTGACTGCGGTAT
TTGCCTGTTTCGTCCTTTCAGAATGCCTGGGTAATGAGTCCGGAATTCTGGCGGTAGCTATCTTCGGGATCATACTTGGG
ACTTCGGAGTTCCCTTACAAGGAGACTATCAAGGAGTTCAAAGGCGATATTGTTACTGTGATGCTCTCCCTTATTTTTAT
CCTGCTTGCGGCAATGCTTGAATTTGAAGATATCCAGAGAATAGGGGTAAGCGGGATAGTCCTTGTATTGCTTCTCGTAT
TTGTTATCCGCCCTATGGCGGTTTTCATCTCCATGTGGAACTCTCAGGTCCGCACAAACGAGAAACTTTTTCTGTCCTTT
ATCGGGCCCAGGGGTGTTGTCCCGACTTCGGTTGCGACTTATTTTGCAATCAAACTTGATTCTATGGGAATTCTGGGTGG
GCAGAGCCTTGTAGGGCTTGTTTTTCTTACGGTTATTATTACGGTCTTTTTGAGTGGAAGCCTATCAAAAAAAGTGGCAG
AAATGCTGGAGGTAATCCCTATGGAAATTCTTATTATTGGTGGAGGAAAGGTAGGTAGAATCCTTGCCGAACGTTTTGAC
AGAAGAGGAGAAAATGTAATTGTCGTGGATATTTCAGAGAGCAACTGCAAGAAATGTATGGAACTCGGGATCCGGATAAT
CCAGGGTGATGCAGGAGATGTAAATGTCATGAAAAAGGCAGGAATAGAGAATGCCAAATATGTGGTTGCAACAACCAATA
AAGATGATACCAACCTTCTCTTCTGCCAGATTGCTAAAACCTGTTTCGGATTCAGGGGTGATCAGCTGGTAGCCAGGGTA
AATGAGATCGAAAACCTTCAGGCTTTCTGGAATCTGGGAATACGCGCCATTAGCCCTTCAATGACCACTGCAGTGATGCT
TGAAAATATGATCGGAAGGCCTCATCTGTTTTCTATGTGCGAAGTAGGAGGCGAAGGGGAAATGATGGAAGTCAAGGTCA
CAAATCCCAGGGTGGTCGGAAGAGCCATCAAGGATATCCAGTTTCCTGAAAAAAGTCTCCTGGTTATGGTTCAGCGGGGG
AGTGATTCTATTATTGCTCACGGAAGCCTTGTGCTTGAATATGAAGATATAGTAACCATCATTGGGGAAGGAGATGCAGC
CAAGCAGACTGCCAGCATACTTTATAAGTAA

Upstream 100 bases:

>100_bases
CCTGATGTTCCCCTAATCTTTTAGTGAGTAATACATCTTTGCAGGGAGTCTCATGCTTGATCCTATACTCTTACTTGGGC
TTGTAGTTTCTGTGCTCGTT

Downstream 100 bases:

>100_bases
TTTCAATTAATATGTGAGATCTCCTCTGCCGGGAAAACTGTAAAACAAAACAAAATCTGTAAAACAAAACTAAATCTGTA
AATCCGGCATAAAATTGTAA

Product: Na(+)/H(+) antiporter

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MSLAARALSYYFRLPFIIFLLIEGIIAGPEVLNLLDPSLYIEGLSAIVAISISVIVFDGGLHIDLKHIRMVQESVLKLTT
IGVLVTFLGTTALTSILIDIPLEIAALFGALVTATGPTVITPIVRNIQISHRLGKILELEGVLNDAASVILAAMVFEWVA
AELSGTDAVIFIFYRLGIGIALGSLSGFALRWFFTRKIAFSKQTVRLVSLTAVFACFVLSECLGNESGILAVAIFGIILG
TSEFPYKETIKEFKGDIVTVMLSLIFILLAAMLEFEDIQRIGVSGIVLVLLLVFVIRPMAVFISMWNSQVRTNEKLFLSF
IGPRGVVPTSVATYFAIKLDSMGILGGQSLVGLVFLTVIITVFLSGSLSKKVAEMLEVIPMEILIIGGGKVGRILAERFD
RRGENVIVVDISESNCKKCMELGIRIIQGDAGDVNVMKKAGIENAKYVVATTNKDDTNLLFCQIAKTCFGFRGDQLVARV
NEIENLQAFWNLGIRAISPSMTTAVMLENMIGRPHLFSMCEVGGEGEMMEVKVTNPRVVGRAIKDIQFPEKSLLVMVQRG
SDSIIAHGSLVLEYEDIVTIIGEGDAAKQTASILYK

Sequences:

>Translated_596_residues
MSLAARALSYYFRLPFIIFLLIEGIIAGPEVLNLLDPSLYIEGLSAIVAISISVIVFDGGLHIDLKHIRMVQESVLKLTT
IGVLVTFLGTTALTSILIDIPLEIAALFGALVTATGPTVITPIVRNIQISHRLGKILELEGVLNDAASVILAAMVFEWVA
AELSGTDAVIFIFYRLGIGIALGSLSGFALRWFFTRKIAFSKQTVRLVSLTAVFACFVLSECLGNESGILAVAIFGIILG
TSEFPYKETIKEFKGDIVTVMLSLIFILLAAMLEFEDIQRIGVSGIVLVLLLVFVIRPMAVFISMWNSQVRTNEKLFLSF
IGPRGVVPTSVATYFAIKLDSMGILGGQSLVGLVFLTVIITVFLSGSLSKKVAEMLEVIPMEILIIGGGKVGRILAERFD
RRGENVIVVDISESNCKKCMELGIRIIQGDAGDVNVMKKAGIENAKYVVATTNKDDTNLLFCQIAKTCFGFRGDQLVARV
NEIENLQAFWNLGIRAISPSMTTAVMLENMIGRPHLFSMCEVGGEGEMMEVKVTNPRVVGRAIKDIQFPEKSLLVMVQRG
SDSIIAHGSLVLEYEDIVTIIGEGDAAKQTASILYK
>Mature_595_residues
SLAARALSYYFRLPFIIFLLIEGIIAGPEVLNLLDPSLYIEGLSAIVAISISVIVFDGGLHIDLKHIRMVQESVLKLTTI
GVLVTFLGTTALTSILIDIPLEIAALFGALVTATGPTVITPIVRNIQISHRLGKILELEGVLNDAASVILAAMVFEWVAA
ELSGTDAVIFIFYRLGIGIALGSLSGFALRWFFTRKIAFSKQTVRLVSLTAVFACFVLSECLGNESGILAVAIFGIILGT
SEFPYKETIKEFKGDIVTVMLSLIFILLAAMLEFEDIQRIGVSGIVLVLLLVFVIRPMAVFISMWNSQVRTNEKLFLSFI
GPRGVVPTSVATYFAIKLDSMGILGGQSLVGLVFLTVIITVFLSGSLSKKVAEMLEVIPMEILIIGGGKVGRILAERFDR
RGENVIVVDISESNCKKCMELGIRIIQGDAGDVNVMKKAGIENAKYVVATTNKDDTNLLFCQIAKTCFGFRGDQLVARVN
EIENLQAFWNLGIRAISPSMTTAVMLENMIGRPHLFSMCEVGGEGEMMEVKVTNPRVVGRAIKDIQFPEKSLLVMVQRGS
DSIIAHGSLVLEYEDIVTIIGEGDAAKQTASILYK

Specific function: Part of a potassium transport system [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=322, Percent_Identity=25.1552795031056, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789685, Length=215, Percent_Identity=27.906976744186, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 64772; Mature: 64641

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAARALSYYFRLPFIIFLLIEGIIAGPEVLNLLDPSLYIEGLSAIVAISISVIVFDGG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEEEECC
LHIDLKHIRMVQESVLKLTTIGVLVTFLGTTALTSILIDIPLEIAALFGALVTATGPTVI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHH
TPIVRNIQISHRLGKILELEGVLNDAASVILAAMVFEWVAAELSGTDAVIFIFYRLGIGI
HHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALGSLSGFALRWFFTRKIAFSKQTVRLVSLTAVFACFVLSECLGNESGILAVAIFGIILG
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
TSEFPYKETIKEFKGDIVTVMLSLIFILLAAMLEFEDIQRIGVSGIVLVLLLVFVIRPMA
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VFISMWNSQVRTNEKLFLSFIGPRGVVPTSVATYFAIKLDSMGILGGQSLVGLVFLTVII
HHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHEEEEEECCCCCCCCHHHHHHHHHHHHH
TVFLSGSLSKKVAEMLEVIPMEILIIGGGKVGRILAERFDRRGENVIVVDISESNCKKCM
HHHHCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
ELGIRIIQGDAGDVNVMKKAGIENAKYVVATTNKDDTNLLFCQIAKTCFGFRGDQLVARV
HHCCEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHH
NEIENLQAFWNLGIRAISPSMTTAVMLENMIGRPHLFSMCEVGGEGEMMEVKVTNPRVVG
HHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCHHHH
RAIKDIQFPEKSLLVMVQRGSDSIIAHGSLVLEYEDIVTIIGEGDAAKQTASILYK
HHHHHCCCCCCCEEEEEECCCCCEEECCEEEEEEHHEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
SLAARALSYYFRLPFIIFLLIEGIIAGPEVLNLLDPSLYIEGLSAIVAISISVIVFDGG
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEEEECC
LHIDLKHIRMVQESVLKLTTIGVLVTFLGTTALTSILIDIPLEIAALFGALVTATGPTVI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHH
TPIVRNIQISHRLGKILELEGVLNDAASVILAAMVFEWVAAELSGTDAVIFIFYRLGIGI
HHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALGSLSGFALRWFFTRKIAFSKQTVRLVSLTAVFACFVLSECLGNESGILAVAIFGIILG
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
TSEFPYKETIKEFKGDIVTVMLSLIFILLAAMLEFEDIQRIGVSGIVLVLLLVFVIRPMA
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VFISMWNSQVRTNEKLFLSFIGPRGVVPTSVATYFAIKLDSMGILGGQSLVGLVFLTVII
HHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHEEEEEECCCCCCCCHHHHHHHHHHHHH
TVFLSGSLSKKVAEMLEVIPMEILIIGGGKVGRILAERFDRRGENVIVVDISESNCKKCM
HHHHCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
ELGIRIIQGDAGDVNVMKKAGIENAKYVVATTNKDDTNLLFCQIAKTCFGFRGDQLVARV
HHCCEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHH
NEIENLQAFWNLGIRAISPSMTTAVMLENMIGRPHLFSMCEVGGEGEMMEVKVTNPRVVG
HHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCHHHH
RAIKDIQFPEKSLLVMVQRGSDSIIAHGSLVLEYEDIVTIIGEGDAAKQTASILYK
HHHHHCCCCCCCEEEEEECCCCCEEECCEEEEEEHHEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]