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The map label for this gene is fwdB [H]

Identifier: 21226161

GI number: 21226161

Start: 78236

End: 79480

Strand: Direct

Name: fwdB [H]

Synonym: MM_0059

Alternate gene names: 21226161

Gene position: 78236-79480 (Clockwise)

Preceding gene: 21226160

Following gene: 21226162

Centisome position: 1.91

GC content: 46.02

Gene sequence:

>1245_bases
ATGGAGAAAAACTATTACGTATGCACAGGCTGCGGGATGCTCTGCGATGACATAGAAGTAGATGTTGAAAATAATAAAAT
AAATAAAGTCTATACTGCCTGCAGGATAGGGGTAGCCCACATGAAAGACGGGAAGGAAAGTGCCGCTTTCCTGGTAGACA
ATAAACCCGTAGACGAAACAACTGCTATCAGCGAGGCTGCAACTATCCTGAAGAATGCAAAAAACCCTCTTATTTTCGGG
CTTGGGACTTCCAGCAACGAAGCCCAGAAACTTGCGATCGAGCTTGCAAAAAAAACCAGTGCAACTCTGGATGATGCTTC
TTCATTTAGCCTTGGTGAAGTAATTGAAGCTCTCCTTAACAACAAAACCAAGGTCTGCACTCTTGATGATGTAAGGAACA
AAGCCGATGTTTCTATTTTCTGGGGAACAGACCCTTCGGACTCTCACCCGCGTCAACTTTCTAAATACGCCTATTTCCCC
AGGGGGACTGAAAAGCAGAGAGGCTGGGAAGAAGAGAGGACTGCAATTTGCATAGATGTCCGGAAGTCACATACTGCAAA
GATCTGTGGGAATTATTTCTTCCAGATCCCTCCTGGAGGAGATGCCGAGTTTATTGACGCCCTTATTGCAGCGCTTGCCG
GAAAGCTCCCAAAAACCTCTTACAACTTCCCCCCCAAGAGAATCCTTGAGCTGGCAAATATCCTCAAAGGAGCAAAATTC
GGCGTAGTTTTCGCAGGGCGTGGTCTTGTTTATTCTCTGGATAACCTCGAACCTCTTATCCGGCTCATGAACGCCCTGAA
CGAAAAAGCAAACTTCCATCTCGTACCCATGATAAGACAGTACAATACACGGGGCTTTAATGAAAACCTCTTTAAGGAAA
CCGGGTACGTGAACAGTGTAAAATTTGAAGACGGGACTGTGAAACACGGGCCGGAATATTCTGTCGTTGAATCTCTTAAA
GAAAAAACAGTTGATGCCGCACTTATCATTGGTTCGGACCCGTTCTCAATCCTTCCCAGGTCTATTGCAAAGAACCTGCT
TGAAGTCCCCGTGATCGTGCTCGACCCCTGTGAAACCCTCACATCCAGAAATGCAAAAGTTTACATCAGCACTGCAATCG
ATGGAGTAGAGTCAGGAGGAAGTGCAATACGTATGGACGGGGTGAAGGTTGACTTTAAGCCTGCCGTTGAGACAAAACGC
CCTTCGGATGAAACAGTTCTCAAAAAGATAATGGAGGCTCTCTGA

Upstream 100 bases:

>100_bases
CCTGGGGGAGTGCCGCAGATTCGGGAAGAACAAGATCCTCTGTAATGGCTGTATAGTGACCTGCCCTGTAGAGGCAATCG
AGTTTGTGTGAGGCGAGAGG

Downstream 100 bases:

>100_bases
TGGATTTCGGATCTTTTCTTAAAGCCCCTGAAATAAAGGTAAAGATTGTAACCTACAGGGATATCTTTCAGGACAAAGCC
ATGATTGAAAACCGGTTCGG

Product: tungsten formylmethanofuran dehydrogenase subunit B

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MEKNYYVCTGCGMLCDDIEVDVENNKINKVYTACRIGVAHMKDGKESAAFLVDNKPVDETTAISEAATILKNAKNPLIFG
LGTSSNEAQKLAIELAKKTSATLDDASSFSLGEVIEALLNNKTKVCTLDDVRNKADVSIFWGTDPSDSHPRQLSKYAYFP
RGTEKQRGWEEERTAICIDVRKSHTAKICGNYFFQIPPGGDAEFIDALIAALAGKLPKTSYNFPPKRILELANILKGAKF
GVVFAGRGLVYSLDNLEPLIRLMNALNEKANFHLVPMIRQYNTRGFNENLFKETGYVNSVKFEDGTVKHGPEYSVVESLK
EKTVDAALIIGSDPFSILPRSIAKNLLEVPVIVLDPCETLTSRNAKVYISTAIDGVESGGSAIRMDGVKVDFKPAVETKR
PSDETVLKKIMEAL

Sequences:

>Translated_414_residues
MEKNYYVCTGCGMLCDDIEVDVENNKINKVYTACRIGVAHMKDGKESAAFLVDNKPVDETTAISEAATILKNAKNPLIFG
LGTSSNEAQKLAIELAKKTSATLDDASSFSLGEVIEALLNNKTKVCTLDDVRNKADVSIFWGTDPSDSHPRQLSKYAYFP
RGTEKQRGWEEERTAICIDVRKSHTAKICGNYFFQIPPGGDAEFIDALIAALAGKLPKTSYNFPPKRILELANILKGAKF
GVVFAGRGLVYSLDNLEPLIRLMNALNEKANFHLVPMIRQYNTRGFNENLFKETGYVNSVKFEDGTVKHGPEYSVVESLK
EKTVDAALIIGSDPFSILPRSIAKNLLEVPVIVLDPCETLTSRNAKVYISTAIDGVESGGSAIRMDGVKVDFKPAVETKR
PSDETVLKKIMEAL
>Mature_414_residues
MEKNYYVCTGCGMLCDDIEVDVENNKINKVYTACRIGVAHMKDGKESAAFLVDNKPVDETTAISEAATILKNAKNPLIFG
LGTSSNEAQKLAIELAKKTSATLDDASSFSLGEVIEALLNNKTKVCTLDDVRNKADVSIFWGTDPSDSHPRQLSKYAYFP
RGTEKQRGWEEERTAICIDVRKSHTAKICGNYFFQIPPGGDAEFIDALIAALAGKLPKTSYNFPPKRILELANILKGAKF
GVVFAGRGLVYSLDNLEPLIRLMNALNEKANFHLVPMIRQYNTRGFNENLFKETGYVNSVKFEDGTVKHGPEYSVVESLK
EKTVDAALIIGSDPFSILPRSIAKNLLEVPVIVLDPCETLTSRNAKVYISTAIDGVESGGSAIRMDGVKVDFKPAVETKR
PSDETVLKKIMEAL

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 45474; Mature: 45474

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNYYVCTGCGMLCDDIEVDVENNKINKVYTACRIGVAHMKDGKESAAFLVDNKPVDET
CCCCEEEEECCCCEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
TAISEAATILKNAKNPLIFGLGTSSNEAQKLAIELAKKTSATLDDASSFSLGEVIEALLN
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
NKTKVCTLDDVRNKADVSIFWGTDPSDSHPRQLSKYAYFPRGTEKQRGWEEERTAICIDV
CCCEEEEHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHCCCCHHCCEEEEEE
RKSHTAKICGNYFFQIPPGGDAEFIDALIAALAGKLPKTSYNFPPKRILELANILKGAKF
CCCCHHEEECCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCE
GVVFAGRGLVYSLDNLEPLIRLMNALNEKANFHLVPMIRQYNTRGFNENLFKETGYVNSV
EEEEECCCEEEECCCHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHCCCCEEE
KFEDGTVKHGPEYSVVESLKEKTVDAALIIGSDPFSILPRSIAKNLLEVPVIVLDPCETL
EECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEECCHHHH
TSRNAKVYISTAIDGVESGGSAIRMDGVKVDFKPAVETKRPSDETVLKKIMEAL
HCCCCEEEEEEEECCCCCCCCEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MEKNYYVCTGCGMLCDDIEVDVENNKINKVYTACRIGVAHMKDGKESAAFLVDNKPVDET
CCCCEEEEECCCCEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
TAISEAATILKNAKNPLIFGLGTSSNEAQKLAIELAKKTSATLDDASSFSLGEVIEALLN
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
NKTKVCTLDDVRNKADVSIFWGTDPSDSHPRQLSKYAYFPRGTEKQRGWEEERTAICIDV
CCCEEEEHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHCCCCHHCCEEEEEE
RKSHTAKICGNYFFQIPPGGDAEFIDALIAALAGKLPKTSYNFPPKRILELANILKGAKF
CCCCHHEEECCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCE
GVVFAGRGLVYSLDNLEPLIRLMNALNEKANFHLVPMIRQYNTRGFNENLFKETGYVNSV
EEEEECCCEEEECCCHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHCCCCEEE
KFEDGTVKHGPEYSVVESLKEKTVDAALIIGSDPFSILPRSIAKNLLEVPVIVLDPCETL
EECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEECCHHHH
TSRNAKVYISTAIDGVESGGSAIRMDGVKVDFKPAVETKRPSDETVLKKIMEAL
HCCCCEEEEEEEECCCCCCCCEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]