Click here to switch to the map view.

The map label for this gene is uppS [H]

Identifier: 21226116

GI number: 21226116

Start: 16177

End: 16548

Strand: Direct

Name: uppS [H]

Synonym: MM_0014

Alternate gene names: 21226116

Gene position: 16177-16548 (Clockwise)

Preceding gene: 21226115

Following gene: 21226118

Centisome position: 0.39

GC content: 37.37

Gene sequence:

>372_bases
GTGGTGGGGAATACTAATTCGGATATATTTCCAGAAGAATTGCTTGAATATACAAAGAGAACCAAAGTTGGAAAAGGTAA
AATAAAGATAAATTTTTTGATAAATTATGGCTGGTACTGGGATTTAACATATGCATATGATAACTCCCCTGACGGTAAAA
AAATGATAGAGAATATTGCATCAGCAGAAATTCCAAGAGTAGACCTGCTTATTCGCTGGGGAGGAAGATGTAGACTCAGT
GGAATGCTACCGGTTCAAACAGTATATTCGGACATATATGTGGTAGACGAAATGTGGCCGGACTTTAAGCCAGAACACTT
ATTCAAAGCACTGGAATTTTATCAAAACCAGGATATTACACTGGGTGGGTAA

Upstream 100 bases:

>100_bases
TCAGGATAATACAAAAAGGCCTCAAATTCAGAGAAAAGCGTTTACAGATGCCTGTATAAAATCAGTTCAGGAAATTGCAA
AACGTGATGCTGAAATACTT

Downstream 100 bases:

>100_bases
AAAGAGATATTCCTGTTTAATTGGTCAGTATTATCTAATCTTTGCAGATTTATCTGATCTTTGCAGATTTATCTGATCTT
TGCGGATTTAGCTGATCTTT

Product: undecaprenyl pyrophosphate synthetase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MVGNTNSDIFPEELLEYTKRTKVGKGKIKINFLINYGWYWDLTYAYDNSPDGKKMIENIASAEIPRVDLLIRWGGRCRLS
GMLPVQTVYSDIYVVDEMWPDFKPEHLFKALEFYQNQDITLGG

Sequences:

>Translated_123_residues
MVGNTNSDIFPEELLEYTKRTKVGKGKIKINFLINYGWYWDLTYAYDNSPDGKKMIENIASAEIPRVDLLIRWGGRCRLS
GMLPVQTVYSDIYVVDEMWPDFKPEHLFKALEFYQNQDITLGG
>Mature_123_residues
MVGNTNSDIFPEELLEYTKRTKVGKGKIKINFLINYGWYWDLTYAYDNSPDGKKMIENIASAEIPRVDLLIRWGGRCRLS
GMLPVQTVYSDIYVVDEMWPDFKPEHLFKALEFYQNQDITLGG

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786371, Length=139, Percent_Identity=26.6187050359712, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 14306; Mature: 14306

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGNTNSDIFPEELLEYTKRTKVGKGKIKINFLINYGWYWDLTYAYDNSPDGKKMIENIA
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCEEEEEEEEECCCCCHHHHHHHHH
SAEIPRVDLLIRWGGRCRLSGMLPVQTVYSDIYVVDEMWPDFKPEHLFKALEFYQNQDIT
HCCCCEEEEEEEECCEEEECCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCCCCEE
LGG
ECC
>Mature Secondary Structure
MVGNTNSDIFPEELLEYTKRTKVGKGKIKINFLINYGWYWDLTYAYDNSPDGKKMIENIA
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCEEEEEEEEECCCCCHHHHHHHHH
SAEIPRVDLLIRWGGRCRLSGMLPVQTVYSDIYVVDEMWPDFKPEHLFKALEFYQNQDIT
HCCCCEEEEEEEECCEEEECCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCCCCEE
LGG
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]