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The map label for this gene is PtsG [H]

Identifier: 20806976

GI number: 20806976

Start: 481633

End: 482982

Strand: Direct

Name: PtsG [H]

Synonym: TTE0468

Alternate gene names: 20806976

Gene position: 481633-482982 (Clockwise)

Preceding gene: 20806974

Following gene: 20806977

Centisome position: 17.91

GC content: 40.96

Gene sequence:

>1350_bases
ATGCTTCCAGTAGCTGTATTGCCTGCAGCAGCATTACTTTTAAGGCTTGGTGCGCCTGATGTTTTCAATATCCCATTTAT
TATGCAGGCAGGTGCAGCAGTATTTGATAATTTGCCTTTAATATTTGCTGTTGGTATCGCTATAGGCTTTGCCGAAGGGG
ATGGAGTAGCAGCTTTAGCAGCAGCTGTAGGGTATTTCGTGCTAACAAAAGGTGCTACTACAATAAACAAAGATATAAAC
ATGGGAGTTTTAGGCGGTATCTTAATGGGTATAATAGCTGGATACCTTTATAATAAGTACCATGACACAAAACTTCCCGA
TTTCCTGGGATTTTTTGGCGGCAAGAGGTTTGTACCTATTGTGACGGCATTTGCAGCGATTGTATTAGCTCTCATAATGG
GATATGTATGGCCGCCTATACAGAATGGCATCTATGCCGTAGGTGAATGGATTATAGGAGCAGGAGCTTTGGGAGTATTC
GTGTATGGAGTATTGAACAGATTGCTCATTCCTTTTGGACTGCACCACGTTATAAACAGCCTTGTGTGGTTTGTGTTTGG
AACTTTTAAGACGCCTGCTGGTAAAATTGTGACAGGAGACTTAAACAGGTTTTTTGCGGGAGACCCGACGGCAGGAATTT
TTATGGCAGGCTTTTACCCAATAATGATGTTCGGACTTCCAGCAGCAGCATTGGCTATGTGGGCAGCAGCTAAGCCAGAG
CAGAGAAAAGTTGTATCTGGTGTGTTTATAAGCGCTGCTTTGACATCTTTCTTGACAGGGATTACAGAACCCATTGAATT
TTCCTTCATGTTTTTAGCGCCGGTGCTTTATGTAATACATGCCCTTTTGACAGGTCTTTCACTCGCTGTAACTTACGTGC
TCGGGATAAAGAATGGATTTGGCTTTTCAGCAGGACTCATTGACTACATTTTAAGCTATGGAATTGCCACAAAGCCTCTA
TTGTTAGTAGTAATAGGAGTAATTTACGGAGTTGTGTACTATGTAATTTTCTACTATGTTATAACTAAGTTCAACCTACC
TACACCTGGAAGATTAGAGGAAGAAGCTCAAGACCAGTACAGAGATATGTCTAAATCAGAAATAAGCGATGTAGCAGCAC
AATACGTGGAGGTATTGGGAGGTTCTGACAATATTGAATCTTTAGAAGCCTGCATTACCAGGTTGCGCCTTACTGTAAAA
GACGATACAATAGTAGATGATGAGAAATTGAAAAAGTTAGGTGCAACTGGTGTAATGAGGATGGGCAAAAATGCTCTTCA
AGTGATTGTGGGTACTAAAGCGGATTTGATTGCTCAAGAGATGAAAAAGCATATGAAGAAAAAATCTTAA

Upstream 100 bases:

>100_bases
AGACCTTGCCGGCTCTTTTGTTTTAATGCCTGAAAATAAATTAAAAGGAGGGTATTATATGAAATGGCTGGGAAGCCTTC
AAAAACTAGGTAAAGCATTA

Downstream 100 bases:

>100_bases
TGACAATTTTGGCGGCCGATGGGGGCCGCCATCAAAGTTTTAGAAAATGGAGAAAGGGATGGTAGTGATGTTTGGACTCT
TTAAAAGGAAAAAATACGTA

Product: phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Products: NA

Alternate protein names: EIICBA-Nag; EII-Nag; N-acetylglucosamine permease IIC component; PTS system N-acetylglucosamine-specific EIIC component; N-acetylglucosamine-specific phosphotransferase enzyme IIB component; PTS system N-acetylglucosamine-specific EIIB component; N-acetylglucosamine-specific phosphotransferase enzyme IIA component; PTS system N-acetylglucosamine-specific EIIA component [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MLPVAVLPAAALLLRLGAPDVFNIPFIMQAGAAVFDNLPLIFAVGIAIGFAEGDGVAALAAAVGYFVLTKGATTINKDIN
MGVLGGILMGIIAGYLYNKYHDTKLPDFLGFFGGKRFVPIVTAFAAIVLALIMGYVWPPIQNGIYAVGEWIIGAGALGVF
VYGVLNRLLIPFGLHHVINSLVWFVFGTFKTPAGKIVTGDLNRFFAGDPTAGIFMAGFYPIMMFGLPAAALAMWAAAKPE
QRKVVSGVFISAALTSFLTGITEPIEFSFMFLAPVLYVIHALLTGLSLAVTYVLGIKNGFGFSAGLIDYILSYGIATKPL
LLVVIGVIYGVVYYVIFYYVITKFNLPTPGRLEEEAQDQYRDMSKSEISDVAAQYVEVLGGSDNIESLEACITRLRLTVK
DDTIVDDEKLKKLGATGVMRMGKNALQVIVGTKADLIAQEMKKHMKKKS

Sequences:

>Translated_449_residues
MLPVAVLPAAALLLRLGAPDVFNIPFIMQAGAAVFDNLPLIFAVGIAIGFAEGDGVAALAAAVGYFVLTKGATTINKDIN
MGVLGGILMGIIAGYLYNKYHDTKLPDFLGFFGGKRFVPIVTAFAAIVLALIMGYVWPPIQNGIYAVGEWIIGAGALGVF
VYGVLNRLLIPFGLHHVINSLVWFVFGTFKTPAGKIVTGDLNRFFAGDPTAGIFMAGFYPIMMFGLPAAALAMWAAAKPE
QRKVVSGVFISAALTSFLTGITEPIEFSFMFLAPVLYVIHALLTGLSLAVTYVLGIKNGFGFSAGLIDYILSYGIATKPL
LLVVIGVIYGVVYYVIFYYVITKFNLPTPGRLEEEAQDQYRDMSKSEISDVAAQYVEVLGGSDNIESLEACITRLRLTVK
DDTIVDDEKLKKLGATGVMRMGKNALQVIVGTKADLIAQEMKKHMKKKS
>Mature_449_residues
MLPVAVLPAAALLLRLGAPDVFNIPFIMQAGAAVFDNLPLIFAVGIAIGFAEGDGVAALAAAVGYFVLTKGATTINKDIN
MGVLGGILMGIIAGYLYNKYHDTKLPDFLGFFGGKRFVPIVTAFAAIVLALIMGYVWPPIQNGIYAVGEWIIGAGALGVF
VYGVLNRLLIPFGLHHVINSLVWFVFGTFKTPAGKIVTGDLNRFFAGDPTAGIFMAGFYPIMMFGLPAAALAMWAAAKPE
QRKVVSGVFISAALTSFLTGITEPIEFSFMFLAPVLYVIHALLTGLSLAVTYVLGIKNGFGFSAGLIDYILSYGIATKPL
LLVVIGVIYGVVYYVIFYYVITKFNLPTPGRLEEEAQDQYRDMSKSEISDVAAQYVEVLGGSDNIESLEACITRLRLTVK
DDTIVDDEKLKKLGATGVMRMGKNALQVIVGTKADLIAQEMKKHMKKKS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=450, Percent_Identity=56, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI1787343, Length=468, Percent_Identity=44.8717948717949, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1787908, Length=507, Percent_Identity=38.2642998027613, Blast_Score=286, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010974 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 48258; Mature: 48258

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HCCHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3284790; 3056518; 8905232; 9278503 [H]