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The map label for this gene is ArgE [H]

Identifier: 20806900

GI number: 20806900

Start: 411451

End: 412554

Strand: Direct

Name: ArgE [H]

Synonym: TTE0388

Alternate gene names: 20806900

Gene position: 411451-412554 (Clockwise)

Preceding gene: 20806898

Following gene: 20806902

Centisome position: 15.3

GC content: 38.32

Gene sequence:

>1104_bases
ATGATTGAGGCGAAAGAACTGCTTAAAGCCCTTATTAAAAAAGCCTCTACTGACCCTCAGCGAGGTGCACTTATTCCCAT
TATTTCAGCCCTTCAATCTATAGGATTGGACTGGAAATTGGAAATGATAGAGGAGGATATGTATAATATTCTTCTTCCTT
TAAGTTCTTCTCCTAAGCTAATAGTAGAAGTTCATTACGATGTAGTTCCCTCTGTTATAGAGGGCTATCAAACAAAAGAG
GGAGAAGAAAATGGGCGAATATACGGAAGAGGGACCTCAGATGTGCTCGGAGGAGTGGCTATTTTATTAGAAGTTTTAAA
AAGGCTTGGGAGGGAATTCCCATGGGAGAGAGCTGGTGTTTGGATAGCATTTGTGGCTGATGAAGAAAAAGGCGGTAAAG
GTTCACGTCATTTGGCTAGTTCTTTGCCATCTACTATACAATACGCTTTGGTGATTGAACCTACACAAAGTAAATTAGCT
TTTTCTTCCTGTGGTGCGTTGGAATATGAATTGATAATAAAAGGAGTTCCCAGCCATGGGAGTATTCCTGAAAGGGGGAA
AAATTCTATTACATGGACTTCAAGATTTATTATAAAAATGGAAGAAACCCTTTCAAAGCTCAACAACCTCTACAATCCAG
ATATTCCCATTCAAATTACTCCCCTTTTTATATCAGGAGGAAGTGAAGAATATTCTGTACCGCATGAGACGCGCCTCAAC
TTTGATATACGCATACCTCCTAAAGTGCCTATTTCTGATGTTGAAAAAGAAGTAAATTCTCTTTTAGAAAATGATAAAGA
TGTAGAAGTTCATTGCAAATTGGTTGAAGAATGGGCTCCTTCGTGGGAGACGGATGAGGACACAGATTTTGGCCAACTTT
TGCAAAAACTTTATAAAGAAGTGTACAATGAAGAACCAATATTTAAAGTGATGGAGAGCTGGACTGACGCCCACAATTTC
TGGGCAAAAGGTATAAAACCCGTGATATGGGGGCCAGGAGATTTAGCTTTGGCTCATACTCCTTTTGAATATATAGATAT
TCAAGAACTGGAAAAAGGAAAAGAATTTCTTGAAAAATTTTTCTACCGATTACTTGAGTTTTAA

Upstream 100 bases:

>100_bases
GCAATATTCATTGTTCAAACTTTCAGTGCTTGACCTAAACATATCAATTTGCTACCATATGGGCAGAGTGTGTTATCCCG
TGTAAAAGAGGTGAGAGCTC

Downstream 100 bases:

>100_bases
ATACATTCTAAGCCACTTACCCGCCTGAGGACCTGGTGTAAAGCCATGCTTCTTGTAGAAATCTTGAGCTTTAGAGTTTT
CTATTCCCACCCAAAGCCCT

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MIEAKELLKALIKKASTDPQRGALIPIISALQSIGLDWKLEMIEEDMYNILLPLSSSPKLIVEVHYDVVPSVIEGYQTKE
GEENGRIYGRGTSDVLGGVAILLEVLKRLGREFPWERAGVWIAFVADEEKGGKGSRHLASSLPSTIQYALVIEPTQSKLA
FSSCGALEYELIIKGVPSHGSIPERGKNSITWTSRFIIKMEETLSKLNNLYNPDIPIQITPLFISGGSEEYSVPHETRLN
FDIRIPPKVPISDVEKEVNSLLENDKDVEVHCKLVEEWAPSWETDEDTDFGQLLQKLYKEVYNEEPIFKVMESWTDAHNF
WAKGIKPVIWGPGDLALAHTPFEYIDIQELEKGKEFLEKFFYRLLEF

Sequences:

>Translated_367_residues
MIEAKELLKALIKKASTDPQRGALIPIISALQSIGLDWKLEMIEEDMYNILLPLSSSPKLIVEVHYDVVPSVIEGYQTKE
GEENGRIYGRGTSDVLGGVAILLEVLKRLGREFPWERAGVWIAFVADEEKGGKGSRHLASSLPSTIQYALVIEPTQSKLA
FSSCGALEYELIIKGVPSHGSIPERGKNSITWTSRFIIKMEETLSKLNNLYNPDIPIQITPLFISGGSEEYSVPHETRLN
FDIRIPPKVPISDVEKEVNSLLENDKDVEVHCKLVEEWAPSWETDEDTDFGQLLQKLYKEVYNEEPIFKVMESWTDAHNF
WAKGIKPVIWGPGDLALAHTPFEYIDIQELEKGKEFLEKFFYRLLEF
>Mature_367_residues
MIEAKELLKALIKKASTDPQRGALIPIISALQSIGLDWKLEMIEEDMYNILLPLSSSPKLIVEVHYDVVPSVIEGYQTKE
GEENGRIYGRGTSDVLGGVAILLEVLKRLGREFPWERAGVWIAFVADEEKGGKGSRHLASSLPSTIQYALVIEPTQSKLA
FSSCGALEYELIIKGVPSHGSIPERGKNSITWTSRFIIKMEETLSKLNNLYNPDIPIQITPLFISGGSEEYSVPHETRLN
FDIRIPPKVPISDVEKEVNSLLENDKDVEVHCKLVEEWAPSWETDEDTDFGQLLQKLYKEVYNEEPIFKVMESWTDAHNF
WAKGIKPVIWGPGDLALAHTPFEYIDIQELEKGKEFLEKFFYRLLEF

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=391, Percent_Identity=23.0179028132992, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 41595; Mature: 41595

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAKELLKALIKKASTDPQRGALIPIISALQSIGLDWKLEMIEEDMYNILLPLSSSPKL
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHEEEECCCCCCE
IVEVHYDVVPSVIEGYQTKEGEENGRIYGRGTSDVLGGVAILLEVLKRLGREFPWERAGV
EEEEEHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIAFVADEEKGGKGSRHLASSLPSTIQYALVIEPTQSKLAFSSCGALEYELIIKGVPSHG
EEEEEEECCCCCCCHHHHHHHCCHHEEEEEEECCCHHHHHHHHCCCEEEEEEEEECCCCC
SIPERGKNSITWTSRFIIKMEETLSKLNNLYNPDIPIQITPLFISGGSEEYSVPHETRLN
CCCCCCCCCEEEHHHHEEHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEE
FDIRIPPKVPISDVEKEVNSLLENDKDVEVHCKLVEEWAPSWETDEDTDFGQLLQKLYKE
EEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VYNEEPIFKVMESWTDAHNFWAKGIKPVIWGPGDLALAHTPFEYIDIQELEKGKEFLEKF
HCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
FYRLLEF
HHHHHCC
>Mature Secondary Structure
MIEAKELLKALIKKASTDPQRGALIPIISALQSIGLDWKLEMIEEDMYNILLPLSSSPKL
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHEEEECCCCCCE
IVEVHYDVVPSVIEGYQTKEGEENGRIYGRGTSDVLGGVAILLEVLKRLGREFPWERAGV
EEEEEHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIAFVADEEKGGKGSRHLASSLPSTIQYALVIEPTQSKLAFSSCGALEYELIIKGVPSHG
EEEEEEECCCCCCCHHHHHHHCCHHEEEEEEECCCHHHHHHHHCCCEEEEEEEEECCCCC
SIPERGKNSITWTSRFIIKMEETLSKLNNLYNPDIPIQITPLFISGGSEEYSVPHETRLN
CCCCCCCCCEEEHHHHEEHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEE
FDIRIPPKVPISDVEKEVNSLLENDKDVEVHCKLVEEWAPSWETDEDTDFGQLLQKLYKE
EEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VYNEEPIFKVMESWTDAHNFWAKGIKPVIWGPGDLALAHTPFEYIDIQELEKGKEFLEKF
HCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
FYRLLEF
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]