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The map label for this gene is BglB2 [H]

Identifier: 20806873

GI number: 20806873

Start: 384674

End: 386023

Strand: Direct

Name: BglB2 [H]

Synonym: TTE0358

Alternate gene names: 20806873

Gene position: 384674-386023 (Clockwise)

Preceding gene: 20806872

Following gene: 20806874

Centisome position: 14.3

GC content: 37.26

Gene sequence:

>1350_bases
GTGATAGAATTGGTAAAATTTCCAAAAGATTTTACTTGGGGAGTAGCTACGTCATCATACCAAATAGAAGGAGCAGTAAA
TGAAGATGGAAGAACTCCTTCTATATGGGATACATTTTCCAAGACAGAAGGGAAAACATATCAAGGCCATACAGGAGATG
TAGCTTGTGATCATTACCACAGATATAAAGAAGACGTACAGATAATGAAAGAAATAGGAGTTAAAGCCTATAGATTTTCC
ATAGCATGGCCAAGAATTTTCCCTGAAGAAGGCAAGTACAACCCGAAAGGAATGGACTTTTACAAGAGGCTGGTAGATGA
ACTGTTGAAAAGAGAGATAATACCGGTAGCGACAATTTATCATTGGGATTTGCCTCAATGGGCGTATGAAAAGAACGGAG
GATGGCTAAATAGAGAGAGTGTGAAATGGTATGTAGAATATGCATCAAAGCTTTTTGAAGAATTAGGGGATGTGATACCT
TTATGGATAACCCATAACGAGCCTTGGTGTTCATCAATATTAAGCTATGGGATAGGGGAGCATGCGCCAGGCCATAAGGA
TTGGAGAGAGGCCTTGATAGCAGCTCATCATATATTGCTTTCTCACGGAGAGGCCGTAAAAGTATTTAGGGACATGAATC
TGAAAGGGGCGCAAATAGGTATAACGTTAAATCTGACACCTGCATATCCGGCGAGTGAAAAAGAAGAAGACAAATTAGCA
GTCCAATATGCAGATGGATTTGCAAATAGGTGGTTTTTAGATCCAATATTTAAAGGCAATTATCCAGAGGATATGATGGA
ATTATATAGTAAAATAATTGGAGAATTTGATTTTATAAGAGAAGGAGATTTAGAGACCATAAGTGTTCCAATAGATTTTC
TTGGAGTCAATTATTATACAAGGAGTATTGTAAAATACAACGAAGATTCCATGTTAAAAGCAGAGAATGTACCGGGGCCA
GGTAAAAAGACAGAGATGGGATGGGAGATAAGCCCAGAGTCCTTGTATGACCTTTTAAAGAGGTTAGACAGAGAATACAC
GAAACTGCCTATGTACATTACGGAAAATGGAGTAGCATTTAAAGATGAAGTAACAGAAGATGGACGAGTGCATGATTATG
AAAGAATAGAATACATAAAAGAACATCTGAAGGCAATAGCGAGGTTCATAGAAGAAGGCGGCAATTTGAAAGGATACTTT
GTATGGTCTTTGTTAGATAATTTTGAATGGGCACATGGATATTCAAAGAGATTTGGAATAGTTTATGTGGATTATGAGAC
ACAAAAAAGAATATTAAAAGATAGTGCATTTTGGTACAAAGGGGTAATAGAAAAAGGTGTAATCGAATGA

Upstream 100 bases:

>100_bases
GTAAGTTATTCAGGTAAGTTAAAAGAGATTAAAATTTTTGACATTACTCAGTTAATAGCAAATATATAAAAATTGTACCA
AAAATCATTAAAGAATAGGA

Downstream 100 bases:

>100_bases
ATACAGCATCTATGAGGCAGGGTATAAATTGTTCTGCCTCTTTATTTCTAAGCAAATACCCTTAAATGGAGTGAGATGAG
ACTATGAATAAATGGTATGC

Product: Beta-glucosidase/6-phospho-beta- glucosidase/beta- galactosidase

Products: NA

Alternate protein names: Amygdalase; Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MIELVKFPKDFTWGVATSSYQIEGAVNEDGRTPSIWDTFSKTEGKTYQGHTGDVACDHYHRYKEDVQIMKEIGVKAYRFS
IAWPRIFPEEGKYNPKGMDFYKRLVDELLKREIIPVATIYHWDLPQWAYEKNGGWLNRESVKWYVEYASKLFEELGDVIP
LWITHNEPWCSSILSYGIGEHAPGHKDWREALIAAHHILLSHGEAVKVFRDMNLKGAQIGITLNLTPAYPASEKEEDKLA
VQYADGFANRWFLDPIFKGNYPEDMMELYSKIIGEFDFIREGDLETISVPIDFLGVNYYTRSIVKYNEDSMLKAENVPGP
GKKTEMGWEISPESLYDLLKRLDREYTKLPMYITENGVAFKDEVTEDGRVHDYERIEYIKEHLKAIARFIEEGGNLKGYF
VWSLLDNFEWAHGYSKRFGIVYVDYETQKRILKDSAFWYKGVIEKGVIE

Sequences:

>Translated_449_residues
MIELVKFPKDFTWGVATSSYQIEGAVNEDGRTPSIWDTFSKTEGKTYQGHTGDVACDHYHRYKEDVQIMKEIGVKAYRFS
IAWPRIFPEEGKYNPKGMDFYKRLVDELLKREIIPVATIYHWDLPQWAYEKNGGWLNRESVKWYVEYASKLFEELGDVIP
LWITHNEPWCSSILSYGIGEHAPGHKDWREALIAAHHILLSHGEAVKVFRDMNLKGAQIGITLNLTPAYPASEKEEDKLA
VQYADGFANRWFLDPIFKGNYPEDMMELYSKIIGEFDFIREGDLETISVPIDFLGVNYYTRSIVKYNEDSMLKAENVPGP
GKKTEMGWEISPESLYDLLKRLDREYTKLPMYITENGVAFKDEVTEDGRVHDYERIEYIKEHLKAIARFIEEGGNLKGYF
VWSLLDNFEWAHGYSKRFGIVYVDYETQKRILKDSAFWYKGVIEKGVIE
>Mature_449_residues
MIELVKFPKDFTWGVATSSYQIEGAVNEDGRTPSIWDTFSKTEGKTYQGHTGDVACDHYHRYKEDVQIMKEIGVKAYRFS
IAWPRIFPEEGKYNPKGMDFYKRLVDELLKREIIPVATIYHWDLPQWAYEKNGGWLNRESVKWYVEYASKLFEELGDVIP
LWITHNEPWCSSILSYGIGEHAPGHKDWREALIAAHHILLSHGEAVKVFRDMNLKGAQIGITLNLTPAYPASEKEEDKLA
VQYADGFANRWFLDPIFKGNYPEDMMELYSKIIGEFDFIREGDLETISVPIDFLGVNYYTRSIVKYNEDSMLKAENVPGP
GKKTEMGWEISPESLYDLLKRLDREYTKLPMYITENGVAFKDEVTEDGRVHDYERIEYIKEHLKAIARFIEEGGNLKGYF
VWSLLDNFEWAHGYSKRFGIVYVDYETQKRILKDSAFWYKGVIEKGVIE

Specific function: Unknown

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=473, Percent_Identity=36.7864693446089, Blast_Score=271, Evalue=7e-73,
Organism=Homo sapiens, GI110681710, Length=475, Percent_Identity=35.5789473684211, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI13273313, Length=473, Percent_Identity=33.1923890063425, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI24497614, Length=463, Percent_Identity=31.317494600432, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI28376633, Length=448, Percent_Identity=32.8125, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI190360571, Length=86, Percent_Identity=41.8604651162791, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI2367174, Length=485, Percent_Identity=32.3711340206186, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI2367270, Length=469, Percent_Identity=33.6886993603412, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789070, Length=475, Percent_Identity=31.3684210526316, Blast_Score=202, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17552856, Length=471, Percent_Identity=33.9702760084926, Blast_Score=254, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17539390, Length=476, Percent_Identity=34.453781512605, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI21356577, Length=461, Percent_Identity=35.7917570498915, Blast_Score=274, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 52307; Mature: 52307

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELVKFPKDFTWGVATSSYQIEGAVNEDGRTPSIWDTFSKTEGKTYQGHTGDVACDHYH
CCEEEECCCCCCCCEECCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCEEHHHHH
RYKEDVQIMKEIGVKAYRFSIAWPRIFPEEGKYNPKGMDFYKRLVDELLKREIIPVATIY
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
HWDLPQWAYEKNGGWLNRESVKWYVEYASKLFEELGDVIPLWITHNEPWCSSILSYGIGE
ECCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCC
HAPGHKDWREALIAAHHILLSHGEAVKVFRDMNLKGAQIGITLNLTPAYPASEKEEDKLA
CCCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCEE
VQYADGFANRWFLDPIFKGNYPEDMMELYSKIIGEFDFIREGDLETISVPIDFLGVNYYT
EEECCCCCCCEEECHHHCCCCCHHHHHHHHHHHCCHHHCCCCCCCEEEECHHHHCCHHHH
RSIVKYNEDSMLKAENVPGPGKKTEMGWEISPESLYDLLKRLDREYTKLPMYITENGVAF
HHHHEECCCCCEEECCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCEEEECCCEEE
KDEVTEDGRVHDYERIEYIKEHLKAIARFIEEGGNLKGYFVWSLLDNFEWAHGYSKRFGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHCCHHHCCCCCCCCE
VYVDYETQKRILKDSAFWYKGVIEKGVIE
EEEECHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIELVKFPKDFTWGVATSSYQIEGAVNEDGRTPSIWDTFSKTEGKTYQGHTGDVACDHYH
CCEEEECCCCCCCCEECCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCEEHHHHH
RYKEDVQIMKEIGVKAYRFSIAWPRIFPEEGKYNPKGMDFYKRLVDELLKREIIPVATIY
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
HWDLPQWAYEKNGGWLNRESVKWYVEYASKLFEELGDVIPLWITHNEPWCSSILSYGIGE
ECCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCC
HAPGHKDWREALIAAHHILLSHGEAVKVFRDMNLKGAQIGITLNLTPAYPASEKEEDKLA
CCCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCEE
VQYADGFANRWFLDPIFKGNYPEDMMELYSKIIGEFDFIREGDLETISVPIDFLGVNYYT
EEECCCCCCCEEECHHHCCCCCHHHHHHHHHHHCCHHHCCCCCCCEEEECHHHHCCHHHH
RSIVKYNEDSMLKAENVPGPGKKTEMGWEISPESLYDLLKRLDREYTKLPMYITENGVAF
HHHHEECCCCCEEECCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCEEEECCCEEE
KDEVTEDGRVHDYERIEYIKEHLKAIARFIEEGGNLKGYFVWSLLDNFEWAHGYSKRFGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHCCHHHCCCCCCCCE
VYVDYETQKRILKDSAFWYKGVIEKGVIE
EEEECHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123813 [H]