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The map label for this gene is moaA [C]

Identifier: 20094510

GI number: 20094510

Start: 1040918

End: 1042417

Strand: Direct

Name: moaA [C]

Synonym: MK1074

Alternate gene names: 20094510

Gene position: 1040918-1042417 (Clockwise)

Preceding gene: 20094503

Following gene: 20094511

Centisome position: 61.41

GC content: 62.93

Gene sequence:

>1500_bases
GTGAGCGACACCCTGTACGAGACCGAGAGCCTCTGCCCCGAATGTCTCCGAGTGGTACCGGCGAGGCTCGTTCGGACCGC
CGAAGGTTCCGTGGAGATAGTTAAGAAGTGCCCGGAACACGGTGAGTTCCGCGAAGTCGTATGGTCCGATGTCGAGTTCT
TCGAACGCGCCTTCGAGTACGAGTTCAAGGGTCCCGGCGTGGAGAACCCACAAACGGACAGCGAGAACGGCTGCCCACTC
GACTGCGGTCTCTGCCCGTGCCACGAGAGTACTACCGCTCTCGGGATCATCGACGTCACGAACCGGTGTAACATGAACTG
TCCCGTATGTTTCGCCAACGCAGAGGCTAAGGGTTACGTGTACGAGCCGTCCCTCGAGCAGATCGAGGAGATGCTTGACT
TATTACGCTCGGAGCGCCCCGTGCCGGCTCCCGCGGTGCAGTTCGCGGGCGGCGAGCCGTTAGTCCGTGAGGACATCGTC
GAGATCGTCGCCGCCGCGGACGAGCGCGGCTTCCACGTACAGATCGCGACGAACGGTGTGGAGTTCGCCCGGAATCCGGA
GCTGGCGGAGGATCTCCACGCCGCCGGACTGAACGTCGTGTACCTGCAGTTCGACGGGCTGAACCCCGAGATCTACGAGG
AGATACGGGGCTCCAGGAAGGTCCTCGAGTTGAAGAAGGAGGCGATCAAGGTCCTCGAGCGCGAGGGGATCTCCACGGTC
CTCGTACCCACGCTGGCCCGCGGGGTCAACGACGATCAGATTCGGCCCATGCTGGACTTCGCCCGCGAGTTCGAGGTCAT
CCGCGGGATCAACGTGCAGCCGATCTCGTTCACGGGTCGAACGCCGCGCGAGGAGCGGGAGCGCATGCGCATCACCATAC
CGGACTTCGTCAAGCTCGTCGAGGAGCAGACGGACGGCCGTATCCCCGCCGAGAGCTTCTACCCGGTCCCGATCGCGGCG
AAGATAGCCCGGCTGATTGGACAACTCCACGGGAAGCGGAAGCCGGAGTTCTCCGCGCACCCGATCTGCGGGGTCGCCAC
CTATCTACTCGACGAAGGGGACTGGTACCGCCCCATCACCGACTACGTCGATCCGGACGCGTTCATCGACGCGCTGGAAG
AGGTCGCGGAGAAGGCGGGATCGTTGGATCGAAAGCGGGATCGAGCGAAGGCCGCTTGGATCGTGACCAAGTACCTACGG
CGCGTCTTCAAGGGCCTCACTGGCAAACGCAAGCTGGCCCGACTGGTCCTCGACGTCGTGACTAAGGGAACCTACGACGC
CCTCGCGGACTTCCACTGGAACGCGCTGCTACTGGGCTGTATGCACTTCATGGACCCGTACAACTTCCAGACGGACCGTG
TGCGACGGTGCGTGATCCACTACGCGACACCGGACGGACGGATCGTACCGTTCTGCCCCTATAACTCCATACACCGTGAA
GAGATCGAGCGGAAGTTCGGCGTGCCGCTCGAGGAGTGGAAGGAACGCCGGAACGGGTGA

Upstream 100 bases:

>100_bases
TCAAGTTCGCGATGTACGCCGGTAGGATGAACCAGAGACCCTTTCCGAGTTCCAACCATGCCCCGCTTCCCATTTCAACC
ATCCCCTCGGGGGTCCGGTA

Downstream 100 bases:

>100_bases
CACGGTTGCCACTCCGCGAGGCGGCCGAGAGGGTTGTAGAGGCCGAGACAGTCGTCGTGCTCACCGGGGCCGGCGCCTCG
GCGGACTCCGGTATCCCGAC

Product: Fe-S oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSDTLYETESLCPECLRVVPARLVRTAEGSVEIVKKCPEHGEFREVVWSDVEFFERAFEYEFKGPGVENPQTDSENGCPL
DCGLCPCHESTTALGIIDVTNRCNMNCPVCFANAEAKGYVYEPSLEQIEEMLDLLRSERPVPAPAVQFAGGEPLVREDIV
EIVAAADERGFHVQIATNGVEFARNPELAEDLHAAGLNVVYLQFDGLNPEIYEEIRGSRKVLELKKEAIKVLEREGISTV
LVPTLARGVNDDQIRPMLDFAREFEVIRGINVQPISFTGRTPREERERMRITIPDFVKLVEEQTDGRIPAESFYPVPIAA
KIARLIGQLHGKRKPEFSAHPICGVATYLLDEGDWYRPITDYVDPDAFIDALEEVAEKAGSLDRKRDRAKAAWIVTKYLR
RVFKGLTGKRKLARLVLDVVTKGTYDALADFHWNALLLGCMHFMDPYNFQTDRVRRCVIHYATPDGRIVPFCPYNSIHRE
EIERKFGVPLEEWKERRNG

Sequences:

>Translated_499_residues
MSDTLYETESLCPECLRVVPARLVRTAEGSVEIVKKCPEHGEFREVVWSDVEFFERAFEYEFKGPGVENPQTDSENGCPL
DCGLCPCHESTTALGIIDVTNRCNMNCPVCFANAEAKGYVYEPSLEQIEEMLDLLRSERPVPAPAVQFAGGEPLVREDIV
EIVAAADERGFHVQIATNGVEFARNPELAEDLHAAGLNVVYLQFDGLNPEIYEEIRGSRKVLELKKEAIKVLEREGISTV
LVPTLARGVNDDQIRPMLDFAREFEVIRGINVQPISFTGRTPREERERMRITIPDFVKLVEEQTDGRIPAESFYPVPIAA
KIARLIGQLHGKRKPEFSAHPICGVATYLLDEGDWYRPITDYVDPDAFIDALEEVAEKAGSLDRKRDRAKAAWIVTKYLR
RVFKGLTGKRKLARLVLDVVTKGTYDALADFHWNALLLGCMHFMDPYNFQTDRVRRCVIHYATPDGRIVPFCPYNSIHRE
EIERKFGVPLEEWKERRNG
>Mature_498_residues
SDTLYETESLCPECLRVVPARLVRTAEGSVEIVKKCPEHGEFREVVWSDVEFFERAFEYEFKGPGVENPQTDSENGCPLD
CGLCPCHESTTALGIIDVTNRCNMNCPVCFANAEAKGYVYEPSLEQIEEMLDLLRSERPVPAPAVQFAGGEPLVREDIVE
IVAAADERGFHVQIATNGVEFARNPELAEDLHAAGLNVVYLQFDGLNPEIYEEIRGSRKVLELKKEAIKVLEREGISTVL
VPTLARGVNDDQIRPMLDFAREFEVIRGINVQPISFTGRTPREERERMRITIPDFVKLVEEQTDGRIPAESFYPVPIAAK
IARLIGQLHGKRKPEFSAHPICGVATYLLDEGDWYRPITDYVDPDAFIDALEEVAEKAGSLDRKRDRAKAAWIVTKYLRR
VFKGLTGKRKLARLVLDVVTKGTYDALADFHWNALLLGCMHFMDPYNFQTDRVRRCVIHYATPDGRIVPFCPYNSIHREE
IERKFGVPLEEWKERRNG

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI22027536, Length=171, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI116734668, Length=171, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 56619; Mature: 56488

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00200 RIESKE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTLYETESLCPECLRVVPARLVRTAEGSVEIVKKCPEHGEFREVVWSDVEFFERAFEY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
EFKGPGVENPQTDSENGCPLDCGLCPCHESTTALGIIDVTNRCNMNCPVCFANAEAKGYV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCEE
YEPSLEQIEEMLDLLRSERPVPAPAVQFAGGEPLVREDIVEIVAAADERGFHVQIATNGV
ECCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
EFARNPELAEDLHAAGLNVVYLQFDGLNPEIYEEIRGSRKVLELKKEAIKVLEREGISTV
CCCCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEE
LVPTLARGVNDDQIRPMLDFAREFEVIRGINVQPISFTGRTPREERERMRITIPDFVKLV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHCEEEEHHHHHHHH
EEQTDGRIPAESFYPVPIAAKIARLIGQLHGKRKPEFSAHPICGVATYLLDEGDWYRPIT
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHH
DYVDPDAFIDALEEVAEKAGSLDRKRDRAKAAWIVTKYLRRVFKGLTGKRKLARLVLDVV
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TKGTYDALADFHWNALLLGCMHFMDPYNFQTDRVRRCVIHYATPDGRIVPFCPYNSIHRE
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEHEEEECCCCCEEEECCCCHHHHH
EIERKFGVPLEEWKERRNG
HHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
SDTLYETESLCPECLRVVPARLVRTAEGSVEIVKKCPEHGEFREVVWSDVEFFERAFEY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
EFKGPGVENPQTDSENGCPLDCGLCPCHESTTALGIIDVTNRCNMNCPVCFANAEAKGYV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCEE
YEPSLEQIEEMLDLLRSERPVPAPAVQFAGGEPLVREDIVEIVAAADERGFHVQIATNGV
ECCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
EFARNPELAEDLHAAGLNVVYLQFDGLNPEIYEEIRGSRKVLELKKEAIKVLEREGISTV
CCCCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEE
LVPTLARGVNDDQIRPMLDFAREFEVIRGINVQPISFTGRTPREERERMRITIPDFVKLV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHCEEEEHHHHHHHH
EEQTDGRIPAESFYPVPIAAKIARLIGQLHGKRKPEFSAHPICGVATYLLDEGDWYRPIT
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCHH
DYVDPDAFIDALEEVAEKAGSLDRKRDRAKAAWIVTKYLRRVFKGLTGKRKLARLVLDVV
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TKGTYDALADFHWNALLLGCMHFMDPYNFQTDRVRRCVIHYATPDGRIVPFCPYNSIHRE
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEHEEEECCCCCEEEECCCCHHHHH
EIERKFGVPLEEWKERRNG
HHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]