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The map label for this gene is NtpC [H]

Identifier: 20094451

GI number: 20094451

Start: 978178

End: 979302

Strand: Direct

Name: NtpC [H]

Synonym: MK1015

Alternate gene names: 20094451

Gene position: 978178-979302 (Clockwise)

Preceding gene: 20094450

Following gene: 20094452

Centisome position: 57.71

GC content: 62.49

Gene sequence:

>1125_bases
TTGCTAGGACTGGCCGGCCTGCAAGATTACACCCTTCTCGCCGTCGGGATCATCGCGCTGGTCACGGTGCTCTCGATAAT
CTTGTCCATACCGATCACCGACGTCGTTTGGCGGTACGCCCCCTACGCTTACCCGCTCCCCAGGGCCAAGGCCGTCGAGG
CGGAGACGCTATCCGACGAGGATTACGAGGAACTCAAGGACGCCCCGGTGCGGGACCTGGTCACCAGGCTCGAGGAGCTC
GGAGTCGAGCCTGAAGCAGCCCGGGCGGTACTCGACGGGAACACGGCTCCACTCGAGATAGAGCTCAAGCGCCGTGCCGT
CGAGTCCGTGATGGAGAGAATCGTCGAGACCAGCCCGGAGGACGTTTCCGAGCTGGCGCGGGCCCTGATAGCCAAGTACG
AGCTAGAAGACATCAAGGCGGTACTGCGTGCGCGCCATGCGGGTGAGGAACCAAAACACCTCGTGGACGCGCCCGTACTG
CTCGGAGCGGAAACCTGGCGAGAGCTAAAGGAAGCGCGCTCAGTCCCGGAGGTCGTAGACTACCTACGCGGAACTCCGTA
CGATCGCGGATTAGAGGAGGCCCTGCGTGAGTACGAGGAGACGGGCTCTCTACTACCGCTGGAGTTGGCCCTTGATAGGG
CTTATTACGAGCACCTGTGGGATCTGGTGGTAAGCGAGAAGGTTGACGAGGAACTGGCCAGGCTGGTCGGCCTTGAGATC
GACCTATACAACGTGGAGGTCGCGCTTCGAGGTGCGATCCTGAACCTGGACCCGGAACGTGTGCTCGAGGCTATGGCGGA
AGGCGGCTGGGAGCTGGCCGAGTGGAGGAAGCGGGAGCTGGCGGAAGCCGAAGATCCCCTAGAGGTCGTCGAGAGACTCT
CAGGGACTTCCCTCGGGCCGTACTTGGAGGAAGCCGCCGAGGAGTACTCGGAAGGGCGTGGAGTTCAGGTCTTCGACGAA
GCCCTCCGTAAAGCCCGCTACGAGCTGGCCCGAGAGATCGCGGGGTCCGATCTCATCGGAGCACCGGCCGTGGTGCACGC
GGTGTACGAGAAGCAGCGTGAGGTCGATAACGTGATCTCCCTAGTCAACGCCAAGGTGGCGGACGTCGAGACCATGTTAG
TGTAG

Upstream 100 bases:

>100_bases
CGGCTCCGAGGCGTACGACAACACCGTCGATGCCCGGCTCCGTCGCCGGCGCTCCGAGATAGTTAGACGGGTCTCGGAGA
CGCTCTTCGGGGGATAACCT

Downstream 100 bases:

>100_bases
GGGGAGCCACCCGTGTACGTAGTAGCCGCCGTGGTGAACGGGTCCGTCGCCTCGGGGTTCAGGCTCGTCGGCGTGCGAAC
GATCGACGCGGACCGTGAGG

Product: vacuolar-type H+-ATPase subunit C

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit C [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MLGLAGLQDYTLLAVGIIALVTVLSIILSIPITDVVWRYAPYAYPLPRAKAVEAETLSDEDYEELKDAPVRDLVTRLEEL
GVEPEAARAVLDGNTAPLEIELKRRAVESVMERIVETSPEDVSELARALIAKYELEDIKAVLRARHAGEEPKHLVDAPVL
LGAETWRELKEARSVPEVVDYLRGTPYDRGLEEALREYEETGSLLPLELALDRAYYEHLWDLVVSEKVDEELARLVGLEI
DLYNVEVALRGAILNLDPERVLEAMAEGGWELAEWRKRELAEAEDPLEVVERLSGTSLGPYLEEAAEEYSEGRGVQVFDE
ALRKARYELAREIAGSDLIGAPAVVHAVYEKQREVDNVISLVNAKVADVETMLV

Sequences:

>Translated_374_residues
MLGLAGLQDYTLLAVGIIALVTVLSIILSIPITDVVWRYAPYAYPLPRAKAVEAETLSDEDYEELKDAPVRDLVTRLEEL
GVEPEAARAVLDGNTAPLEIELKRRAVESVMERIVETSPEDVSELARALIAKYELEDIKAVLRARHAGEEPKHLVDAPVL
LGAETWRELKEARSVPEVVDYLRGTPYDRGLEEALREYEETGSLLPLELALDRAYYEHLWDLVVSEKVDEELARLVGLEI
DLYNVEVALRGAILNLDPERVLEAMAEGGWELAEWRKRELAEAEDPLEVVERLSGTSLGPYLEEAAEEYSEGRGVQVFDE
ALRKARYELAREIAGSDLIGAPAVVHAVYEKQREVDNVISLVNAKVADVETMLV
>Mature_374_residues
MLGLAGLQDYTLLAVGIIALVTVLSIILSIPITDVVWRYAPYAYPLPRAKAVEAETLSDEDYEELKDAPVRDLVTRLEEL
GVEPEAARAVLDGNTAPLEIELKRRAVESVMERIVETSPEDVSELARALIAKYELEDIKAVLRARHAGEEPKHLVDAPVL
LGAETWRELKEARSVPEVVDYLRGTPYDRGLEEALREYEETGSLLPLELALDRAYYEHLWDLVVSEKVDEELARLVGLEI
DLYNVEVALRGAILNLDPERVLEAMAEGGWELAEWRKRELAEAEDPLEVVERLSGTSLGPYLEEAAEEYSEGRGVQVFDE
ALRKARYELAREIAGSDLIGAPAVVHAVYEKQREVDNVISLVNAKVADVETMLV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1527

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase V0D/AC39 subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014272
- InterPro:   IPR002843 [H]

Pfam domain/function: PF01992 vATP-synt_AC39 [H]

EC number: 3.6.3.14

Molecular weight: Translated: 41735; Mature: 41735

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLAGLQDYTLLAVGIIALVTVLSIILSIPITDVVWRYAPYAYPLPRAKAVEAETLSDE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHCCHHHCCCC
DYEELKDAPVRDLVTRLEELGVEPEAARAVLDGNTAPLEIELKRRAVESVMERIVETSPE
CHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCH
DVSELARALIAKYELEDIKAVLRARHAGEEPKHLVDAPVLLGAETWRELKEARSVPEVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCHHHHHHHHHHCCHHHHHH
YLRGTPYDRGLEEALREYEETGSLLPLELALDRAYYEHLWDLVVSEKVDEELARLVGLEI
HHCCCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
DLYNVEVALRGAILNLDPERVLEAMAEGGWELAEWRKRELAEAEDPLEVVERLSGTSLGP
EEEEHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCH
YLEEAAEEYSEGRGVQVFDEALRKARYELAREIAGSDLIGAPAVVHAVYEKQREVDNVIS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVNAKVADVETMLV
HHHHHHHHHHHHCC
>Mature Secondary Structure
MLGLAGLQDYTLLAVGIIALVTVLSIILSIPITDVVWRYAPYAYPLPRAKAVEAETLSDE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHCCHHHCCCC
DYEELKDAPVRDLVTRLEELGVEPEAARAVLDGNTAPLEIELKRRAVESVMERIVETSPE
CHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCH
DVSELARALIAKYELEDIKAVLRARHAGEEPKHLVDAPVLLGAETWRELKEARSVPEVVD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCHHHHHHHHHHCCHHHHHH
YLRGTPYDRGLEEALREYEETGSLLPLELALDRAYYEHLWDLVVSEKVDEELARLVGLEI
HHCCCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
DLYNVEVALRGAILNLDPERVLEAMAEGGWELAEWRKRELAEAEDPLEVVERLSGTSLGP
EEEEHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCH
YLEEAAEEYSEGRGVQVFDEALRKARYELAREIAGSDLIGAPAVVHAVYEKQREVDNVIS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVNAKVADVETMLV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]