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The map label for this gene is yleA [C]

Identifier: 20094234

GI number: 20094234

Start: 757749

End: 759056

Strand: Direct

Name: yleA [C]

Synonym: MK0797

Alternate gene names: 20094234

Gene position: 757749-759056 (Clockwise)

Preceding gene: 20094233

Following gene: 20094235

Centisome position: 44.71

GC content: 62.39

Gene sequence:

>1308_bases
ATGAAGGTCCTGGTCATCTCCCCAGAGTATTACACCTACGGAGCCATAGTAGTCGCGGGAGTTTGCGAGGAACACGGTCA
TAGCACTATCCTCCGACGTTCACCCGATCCGGAGGCCCTCAAGCGGGCGGACGTGCTGATACTATCCCTCCACACCACCC
TACACCTCCTCGATGAGGATATCCTCGAGATAGCTCGCCAGGCCCACGAGTTCGGTAAACCTGTGATCGTCGGCGGACCA
GTTTCTCAAGTTCCGGAGCTCGTTTTAGAGAGGTTTCCCAACGCGATCGTGGCTAAAGGTGAGGCGGAGACGGGGCTTCC
TCCGCTCCTCCAGACCTTGGAGGACGAAGGAGACTTCGAAGACGTCGAGGGAATCGCGCTCCTGAGGGACGGTGAAATCG
TCGACACCGGCTGGCCTCCACCCGCCGATCTAGATGGACCCAGCCCACTCAAGGTTCCGCGCGACCTCGGTCGGCAAGAC
GTCCGCGGAGCGAACGTGTACATAGAGACGCATCGCGGCTGCCCGGGTGCGTGTACCTTCTGCCAGGTTCCGGAGTTCTT
CGGACGCCGTGTCCGCTGGAAGCCCGTAGAGGCGGTTCTCGAGGAAGTCAGGGAGCTTACGCGAGGTGGTGCCCGTCGCT
TCGCGATCTCCGGGGGGACCGTCACGACCTACGGCGACGACGAGGAAGATTTCGTCGAGCTCCTCAAACGCCTCGCGGAC
CTCCTCGGTCGCGAGAACGTTTCCGCTCCCGACGTTCGTGCCGATCTCCTGAACGAGCGCCTCCTCGAGGCTATCCGCGA
TTACACGATCGGTTGGATCTTCCTCGGGATCGAGAGCGGTAGTGATAGGATCCTCCGTGCCATGCGCAAGGGCATCACCG
TCGACGACGTCTGCGAAGCCGTCGAACTGGCCCGGACAGTCGGCGTCCGTGTCGCCGGCTCGTTCATCGTCGGTTATCCG
GGCGAGACCGAGGACGATCTTGAAGCTACCGAGGAGTTACTCACCGAGCTGAACCTCGACGACGTGTTCATCAACCTCGC
CGAGCCCATCCCCGGTACCGAGCTCGGCCGCCTCGTTACCGAGCTTCCCGAGGAGGAGATTCCCGTCCTCCGGCCGGGCG
AGCAGCTCGAGACCGAGGCTGGCGACCGCGCCCTCCAGCTTCAGCTCACAGCCTTCACGACCCTTAGTCGCCCAGTTCCT
CTCACGGACGACGTGTTTCACGAGGCCCTCCACAACATTCGCGAGGACGAGCGCAAGGTTCTCCGGATAACCCGGTTCCT
ACGCGGTGCCCAGGGGTGTACCGGATGA

Upstream 100 bases:

>100_bases
ACGTCATCGGCCGCGTTGTGGAAGGACTCGGCCGCCTCCGCGAGATGGACCAGTCCGACATGGGTCGTACCGTCTACGTT
CGGGAGGTGAGGGGCGAGCG

Downstream 100 bases:

>100_bases
GGATCGCGATACTCGGCGGTACCGGCGCCATGGGCCGTCTTATCGCCCGCGAGCTCCGTGACGACGGTCATGAGGTAGTT
ATCACTGGTTCTAACCCTCA

Product: Fe-S oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKVLVISPEYYTYGAIVVAGVCEEHGHSTILRRSPDPEALKRADVLILSLHTTLHLLDEDILEIARQAHEFGKPVIVGGP
VSQVPELVLERFPNAIVAKGEAETGLPPLLQTLEDEGDFEDVEGIALLRDGEIVDTGWPPPADLDGPSPLKVPRDLGRQD
VRGANVYIETHRGCPGACTFCQVPEFFGRRVRWKPVEAVLEEVRELTRGGARRFAISGGTVTTYGDDEEDFVELLKRLAD
LLGRENVSAPDVRADLLNERLLEAIRDYTIGWIFLGIESGSDRILRAMRKGITVDDVCEAVELARTVGVRVAGSFIVGYP
GETEDDLEATEELLTELNLDDVFINLAEPIPGTELGRLVTELPEEEIPVLRPGEQLETEAGDRALQLQLTAFTTLSRPVP
LTDDVFHEALHNIREDERKVLRITRFLRGAQGCTG

Sequences:

>Translated_435_residues
MKVLVISPEYYTYGAIVVAGVCEEHGHSTILRRSPDPEALKRADVLILSLHTTLHLLDEDILEIARQAHEFGKPVIVGGP
VSQVPELVLERFPNAIVAKGEAETGLPPLLQTLEDEGDFEDVEGIALLRDGEIVDTGWPPPADLDGPSPLKVPRDLGRQD
VRGANVYIETHRGCPGACTFCQVPEFFGRRVRWKPVEAVLEEVRELTRGGARRFAISGGTVTTYGDDEEDFVELLKRLAD
LLGRENVSAPDVRADLLNERLLEAIRDYTIGWIFLGIESGSDRILRAMRKGITVDDVCEAVELARTVGVRVAGSFIVGYP
GETEDDLEATEELLTELNLDDVFINLAEPIPGTELGRLVTELPEEEIPVLRPGEQLETEAGDRALQLQLTAFTTLSRPVP
LTDDVFHEALHNIREDERKVLRITRFLRGAQGCTG
>Mature_435_residues
MKVLVISPEYYTYGAIVVAGVCEEHGHSTILRRSPDPEALKRADVLILSLHTTLHLLDEDILEIARQAHEFGKPVIVGGP
VSQVPELVLERFPNAIVAKGEAETGLPPLLQTLEDEGDFEDVEGIALLRDGEIVDTGWPPPADLDGPSPLKVPRDLGRQD
VRGANVYIETHRGCPGACTFCQVPEFFGRRVRWKPVEAVLEEVRELTRGGARRFAISGGTVTTYGDDEEDFVELLKRLAD
LLGRENVSAPDVRADLLNERLLEAIRDYTIGWIFLGIESGSDRILRAMRKGITVDDVCEAVELARTVGVRVAGSFIVGYP
GETEDDLEATEELLTELNLDDVFINLAEPIPGTELGRLVTELPEEEIPVLRPGEQLETEAGDRALQLQLTAFTTLSRPVP
LTDDVFHEALHNIREDERKVLRITRFLRGAQGCTG

Specific function: Unknown

COG id: COG1032

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylthiotransferase family [H]

Homologues:

Organism=Homo sapiens, GI28872782, Length=234, Percent_Identity=29.0598290598291, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI28872784, Length=234, Percent_Identity=29.0598290598291, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI93277076, Length=201, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786882, Length=236, Percent_Identity=27.9661016949153, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787057, Length=239, Percent_Identity=25.5230125523013, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17553146, Length=227, Percent_Identity=27.7533039647577, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356207, Length=268, Percent_Identity=24.6268656716418, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922432, Length=201, Percent_Identity=28.3582089552239, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR007197 [H]

Pfam domain/function: PF02310 B12-binding; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 48000; Mature: 48000

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVISPEYYTYGAIVVAGVCEEHGHSTILRRSPDPEALKRADVLILSLHTTLHLLDED
CEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHCEEEEEHHHHHHHHHHH
ILEIARQAHEFGKPVIVGGPVSQVPELVLERFPNAIVAKGEAETGLPPLLQTLEDEGDFE
HHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHCCCCCCC
DVEGIALLRDGEIVDTGWPPPADLDGPSPLKVPRDLGRQDVRGANVYIETHRGCPGACTF
CCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCHHCCHHHCCCCEEEEEECCCCCCCCHH
CQVPEFFGRRVRWKPVEAVLEEVRELTRGGARRFAISGGTVTTYGDDEEDFVELLKRLAD
HCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHH
LLGRENVSAPDVRADLLNERLLEAIRDYTIGWIFLGIESGSDRILRAMRKGITVDDVCEA
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCHHHHHHH
VELARTVGVRVAGSFIVGYPGETEDDLEATEELLTELNLDDVFINLAEPIPGTELGRLVT
HHHHHHHHHHEECCEEEECCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHH
ELPEEEIPVLRPGEQLETEAGDRALQLQLTAFTTLSRPVPLTDDVFHEALHNIREDERKV
HCCHHCCCCCCCCHHHHHCCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LRITRFLRGAQGCTG
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVLVISPEYYTYGAIVVAGVCEEHGHSTILRRSPDPEALKRADVLILSLHTTLHLLDED
CEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHCEEEEEHHHHHHHHHHH
ILEIARQAHEFGKPVIVGGPVSQVPELVLERFPNAIVAKGEAETGLPPLLQTLEDEGDFE
HHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHCCCCCCC
DVEGIALLRDGEIVDTGWPPPADLDGPSPLKVPRDLGRQDVRGANVYIETHRGCPGACTF
CCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCHHCCHHHCCCCEEEEEECCCCCCCCHH
CQVPEFFGRRVRWKPVEAVLEEVRELTRGGARRFAISGGTVTTYGDDEEDFVELLKRLAD
HCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHH
LLGRENVSAPDVRADLLNERLLEAIRDYTIGWIFLGIESGSDRILRAMRKGITVDDVCEA
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCHHHHHHH
VELARTVGVRVAGSFIVGYPGETEDDLEATEELLTELNLDDVFINLAEPIPGTELGRLVT
HHHHHHHHHHEECCEEEECCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHH
ELPEEEIPVLRPGEQLETEAGDRALQLQLTAFTTLSRPVPLTDDVFHEALHNIREDERKV
HCCHHCCCCCCCCHHHHHCCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LRITRFLRGAQGCTG
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]