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The map label for this gene is cbiX

Identifier: 20093866

GI number: 20093866

Start: 402254

End: 402685

Strand: Direct

Name: cbiX

Synonym: MK0428

Alternate gene names: 20093866

Gene position: 402254-402685 (Clockwise)

Preceding gene: 20093865

Following gene: 20093867

Centisome position: 23.73

GC content: 56.71

Gene sequence:

>432_bases
ATGGTAGCGGTGGTGTTGGTCGGGCACGGGAGCCGGCTTCCCTACAGTCGGCAAGTCGTCGAAAAAATCGCTGAATACGT
CGAAGAGATGGGCGACTTCGAGACCGTCGAAGTAGGTTTCATGGAGCTATGTGAGCCTACCGTTCAGGAAGCCGTAAAGA
AGGCGGCAGAGTCCGGTGTCGACAAGATAGTCGTCGTACCGGTGTTCCTGGCCCACGGTGTGCATACGAAGAGAGATATC
CCGAAGATGCTAGGGCTGGAACCGGAGTGGGACGATGACGAAGACGACCACGACCATCATCACCACCATCACCGCGACTA
CACGCCCGTAGACGTAGACGCGGAAATAGTGTACGCGGAGCCGCTCGGGGCTGATCCCAGAATCGCCGAGATAGTCATCG
ATAGGATCAAAGAGGCGCTAGGCGAGGAATAA

Upstream 100 bases:

>100_bases
CAACTGGAGCTCTCCGAGGAGCTAAGGGAGTTAGGAGAATATAGAGCCATACAGGCTGTACTCGTGGTCGTTAATACAGT
ACTGGAGGAGGTGTAATACC

Downstream 100 bases:

>100_bases
CCGGGGCCTCCGCTTGATCATCGCCACTCTTACAGGCAGAACCATCGAGGATATGGTGGAACTGGCTATAGAAGCCGTAG
AGCAGGGTGCGGACGCTCTG

Product: sirohydrochlorin cobaltochelatase

Products: NA

Alternate protein names: CbiXS

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MVAVVLVGHGSRLPYSRQVVEKIAEYVEEMGDFETVEVGFMELCEPTVQEAVKKAAESGVDKIVVVPVFLAHGVHTKRDI
PKMLGLEPEWDDDEDDHDHHHHHHRDYTPVDVDAEIVYAEPLGADPRIAEIVIDRIKEALGEE

Sequences:

>Translated_143_residues
MVAVVLVGHGSRLPYSRQVVEKIAEYVEEMGDFETVEVGFMELCEPTVQEAVKKAAESGVDKIVVVPVFLAHGVHTKRDI
PKMLGLEPEWDDDEDDHDHHHHHHRDYTPVDVDAEIVYAEPLGADPRIAEIVIDRIKEALGEE
>Mature_143_residues
MVAVVLVGHGSRLPYSRQVVEKIAEYVEEMGDFETVEVGFMELCEPTVQEAVKKAAESGVDKIVVVPVFLAHGVHTKRDI
PKMLGLEPEWDDDEDDHDHHHHHHRDYTPVDVDAEIVYAEPLGADPRIAEIVIDRIKEALGEE

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIX_METKA (Q8TY77)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613713.1
- ProteinModelPortal:   Q8TY77
- GeneID:   1477731
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0428
- NMPDR:   fig|190192.1.peg.426
- HOGENOM:   HBG686532
- OMA:   FNEPTIP
- ProtClustDB:   PRK00923
- BioCyc:   MKAN190192:MK0428-MONOMER
- BRENDA:   4.99.1.3
- HAMAP:   MF_00785
- InterPro:   IPR002762

Pfam domain/function: PF01903 CbiX

EC number: =4.99.1.3

Molecular weight: Translated: 16083; Mature: 16083

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: ACT_SITE 75-75

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVVLVGHGSRLPYSRQVVEKIAEYVEEMGDFETVEVGFMELCEPTVQEAVKKAAESGV
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCC
DKIVVVPVFLAHGVHTKRDIPKMLGLEPEWDDDEDDHDHHHHHHRDYTPVDVDAEIVYAE
CEEHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
PLGADPRIAEIVIDRIKEALGEE
CCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAVVLVGHGSRLPYSRQVVEKIAEYVEEMGDFETVEVGFMELCEPTVQEAVKKAAESGV
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCC
DKIVVVPVFLAHGVHTKRDIPKMLGLEPEWDDDEDDHDHHHHHHRDYTPVDVDAEIVYAE
CEEHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
PLGADPRIAEIVIDRIKEALGEE
CCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014