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The map label for this gene is fkpB [C]

Identifier: 18977773

GI number: 18977773

Start: 1315411

End: 1316187

Strand: Direct

Name: fkpB [C]

Synonym: PF1401

Alternate gene names: 18977773

Gene position: 1315411-1316187 (Clockwise)

Preceding gene: 18977772

Following gene: 18977774

Centisome position: 68.93

GC content: 38.35

Gene sequence:

>777_bases
ATGAAAGTAGAGAAAGGAGATGTCATAAGACTTCATTACACTGGAAAGGTTAAAGAAACTGGAGAAATCTTCGACACAAC
TTATGAGGATGTTGCAAAAGAAGCTAGAATATACAATCCAAACGGAATCTATGGGCCAGTCCCTATAGCGGTTGGAGCGG
GACACGTATTGCCCGGACTAGACAAGAGACTTATAGGGCTTGAAGTTAAGAAAAAATACGTCATTGAAGTTCCACCCGAA
GAAGGCTTTGGATTGAGAGATCCAGGAAAAATTAAGATTATCCCACTTGGAAAGTTCAGAAAATCTGGAATAATCCCGTA
CCCTGGGCTAGAAATTGAAGTTGAAACAGAAAATGGGAGAAAAATGAGAGGTAGGGTTCTTACAGTTAGCGGAGGAAGAG
TTAGAGTAGACTTCAATCATCCATTAGCAGGAAAGACTCTCGTATATGAAGTTGAAGTTGTTGAGAAAATTGAAGATCCA
ATAGAAAAGATTAAGGCACTAATAGAACTAAGACTGCCAATGATTGACAAAGATAAGGTTATTATTGAGATTAGTGAAAA
AGATGTAAAGCTAAACTTCAAAGACGTTGATATTGATCCAAAGACACTAATTTTGGGCGAAATTCTTCTCGAAAGTGACT
TGAAATTTATAGGATATGAGAAAGTTGAATTTGAGCCAACCATTGAAGAGTTATTAAAGCCCAAGTCTGCCGAGGAGCAA
GAGTCTCCTAACGAAGAACAGCAAGAGGAGAGTGAGTCTAAAGCGGAAGAATCTTAA

Upstream 100 bases:

>100_bases
ACTAAGAGCCGAAGCCATACTACTAGAAAATTTAGTAGGTCTTCAGTTTTCATAATTAAGCTTAAAAATAAACTTTCAAT
ACGGAGTTAGGGGAAGAAAA

Downstream 100 bases:

>100_bases
GGGATAAAATTAGTTAAATACATGGGAGGACCATGAAGAAGATAAAGATACTTGAACAAGACCTCAAGTTGAGACTTCCA
GAAAGAAGCATAGGAAAGGC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKVEKGDVIRLHYTGKVKETGEIFDTTYEDVAKEARIYNPNGIYGPVPIAVGAGHVLPGLDKRLIGLEVKKKYVIEVPPE
EGFGLRDPGKIKIIPLGKFRKSGIIPYPGLEIEVETENGRKMRGRVLTVSGGRVRVDFNHPLAGKTLVYEVEVVEKIEDP
IEKIKALIELRLPMIDKDKVIIEISEKDVKLNFKDVDIDPKTLILGEILLESDLKFIGYEKVEFEPTIEELLKPKSAEEQ
ESPNEEQQEESESKAEES

Sequences:

>Translated_258_residues
MKVEKGDVIRLHYTGKVKETGEIFDTTYEDVAKEARIYNPNGIYGPVPIAVGAGHVLPGLDKRLIGLEVKKKYVIEVPPE
EGFGLRDPGKIKIIPLGKFRKSGIIPYPGLEIEVETENGRKMRGRVLTVSGGRVRVDFNHPLAGKTLVYEVEVVEKIEDP
IEKIKALIELRLPMIDKDKVIIEISEKDVKLNFKDVDIDPKTLILGEILLESDLKFIGYEKVEFEPTIEELLKPKSAEEQ
ESPNEEQQEESESKAEES
>Mature_258_residues
MKVEKGDVIRLHYTGKVKETGEIFDTTYEDVAKEARIYNPNGIYGPVPIAVGAGHVLPGLDKRLIGLEVKKKYVIEVPPE
EGFGLRDPGKIKIIPLGKFRKSGIIPYPGLEIEVETENGRKMRGRVLTVSGGRVRVDFNHPLAGKTLVYEVEVVEKIEDP
IEKIKALIELRLPMIDKDKVIIEISEKDVKLNFKDVDIDPKTLILGEILLESDLKFIGYEKVEFEPTIEELLKPKSAEEQ
ESPNEEQQEESESKAEES

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=154, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29061; Mature: 29061

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVEKGDVIRLHYTGKVKETGEIFDTTYEDVAKEARIYNPNGIYGPVPIAVGAGHVLPGL
CCCCCCCEEEEEECCCCCCCCHHHCCCHHHHHHHCEEECCCCCCCCCEEEECCCCCCCCC
DKRLIGLEVKKKYVIEVPPEEGFGLRDPGKIKIIPLGKFRKSGIIPYPGLEIEVETENGR
CCEEEEEEECCEEEEECCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCEEEEECCCCC
KMRGRVLTVSGGRVRVDFNHPLAGKTLVYEVEVVEKIEDPIEKIKALIELRLPMIDKDKV
EEECEEEEEECCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
IIEISEKDVKLNFKDVDIDPKTLILGEILLESDLKFIGYEKVEFEPTIEELLKPKSAEEQ
EEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCEECEEEEECCCCHHHHCCCCCCCHH
ESPNEEQQEESESKAEES
CCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVEKGDVIRLHYTGKVKETGEIFDTTYEDVAKEARIYNPNGIYGPVPIAVGAGHVLPGL
CCCCCCCEEEEEECCCCCCCCHHHCCCHHHHHHHCEEECCCCCCCCCEEEECCCCCCCCC
DKRLIGLEVKKKYVIEVPPEEGFGLRDPGKIKIIPLGKFRKSGIIPYPGLEIEVETENGR
CCEEEEEEECCEEEEECCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCEEEEECCCCC
KMRGRVLTVSGGRVRVDFNHPLAGKTLVYEVEVVEKIEDPIEKIKALIELRLPMIDKDKV
EEECEEEEEECCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
IIEISEKDVKLNFKDVDIDPKTLILGEILLESDLKFIGYEKVEFEPTIEELLKPKSAEEQ
EEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCEECEEEEECCCCHHHHCCCCCCCHH
ESPNEEQQEESESKAEES
CCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]