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The map label for this gene is appC [H]

Identifier: 18311253

GI number: 18311253

Start: 2609058

End: 2609972

Strand: Reverse

Name: appC [H]

Synonym: CPE2271

Alternate gene names: 18311253

Gene position: 2609972-2609058 (Counterclockwise)

Preceding gene: 18311254

Following gene: 18311252

Centisome position: 86.1

GC content: 32.02

Gene sequence:

>915_bases
ATGCAAACAGAATTAAATAAAGAAGTTAAAGTTAAAAAAGAGAAAATAGAAAGCCCTTGGACTGTAGCTTTTAAAAGATT
GAAAAAAAATAAGTTAGCTTTAGGTGGCTTATTTATATTGTTGGTATTAGTTTTAATTTCAATATTAGGACCAATGTTAT
ATCCACATGATCATTTAACCATAGATTTAGTAAGAACTAATCAACCACCATCAGCGCAGCATTGGCTAGGAACTGATGAA
TCTGGAAGAGATGTTTTAGCTAGACTTATGTACGGGGGAAGATATTCACTTTCAATAGGTATAGTTGCGGTAGGAATTTC
TATAATTATAGGAACAACTTTGGGGATATTAGCAGGATATTATGGAGGATTTATAGATAGTTTAATTATGAGAATTGTTG
ACGTATTTATGTGTTTCCCATTCTTATCATTATTAATAATGGTATCTGCTATAATGTCAGATTTAAAAATACCACCAGAG
TATAGAATTTTTGTAGTTATGTTTATTATAGGGGCACTGAGTTGGACTGGTACATGTCGTATGGTTAGAGGTATGGTCTT
ATCTTTAAGAGAACAAGAATTTATGCAAGCGGCAGAAGCTTTAGGTCTATCAGATGCTAGAAAAATGTTTTTACACTTAT
TACCTAATACATTAGCAGTTATTATAGTTTCAGCTACATTAGGAATTGGTGGAGCTATATTAACAGAATCATCTTTAAGT
TTCTTAGGACTTGGAGTTACACCTCCTACACCAACTTGGGGTAATATGATACAAACAGCTCAAGATTACTATACATTAAC
AAATAGATGGTGGTTATGGATACCTCCAGGAGTATGTATATTCTTAACTGTTATATCTATAAATATTTTTGGAGATGGAT
TAAGAGATGCTCTAGATCCTAAGCTAAAGGTCTAA

Upstream 100 bases:

>100_bases
TTACTTTGGCTATATTAGTTTTAATAGGAAACTTACTTGCTGATATTATATATGCATTAGTAGATCCAAGAATAAGGCTT
AAGTAGGAGGTGCTTTTTAT

Downstream 100 bases:

>100_bases
GGGGGCGAGTGTAATGGGAAAAACATTAGTAGAATTTAAAAATCTTGAAACTCACTTTCATACAGGTGAGGGAATTGTCA
AAGCAGTAAATAACGTTAGT

Product: oligopeptide ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MQTELNKEVKVKKEKIESPWTVAFKRLKKNKLALGGLFILLVLVLISILGPMLYPHDHLTIDLVRTNQPPSAQHWLGTDE
SGRDVLARLMYGGRYSLSIGIVAVGISIIIGTTLGILAGYYGGFIDSLIMRIVDVFMCFPFLSLLIMVSAIMSDLKIPPE
YRIFVVMFIIGALSWTGTCRMVRGMVLSLREQEFMQAAEALGLSDARKMFLHLLPNTLAVIIVSATLGIGGAILTESSLS
FLGLGVTPPTPTWGNMIQTAQDYYTLTNRWWLWIPPGVCIFLTVISINIFGDGLRDALDPKLKV

Sequences:

>Translated_304_residues
MQTELNKEVKVKKEKIESPWTVAFKRLKKNKLALGGLFILLVLVLISILGPMLYPHDHLTIDLVRTNQPPSAQHWLGTDE
SGRDVLARLMYGGRYSLSIGIVAVGISIIIGTTLGILAGYYGGFIDSLIMRIVDVFMCFPFLSLLIMVSAIMSDLKIPPE
YRIFVVMFIIGALSWTGTCRMVRGMVLSLREQEFMQAAEALGLSDARKMFLHLLPNTLAVIIVSATLGIGGAILTESSLS
FLGLGVTPPTPTWGNMIQTAQDYYTLTNRWWLWIPPGVCIFLTVISINIFGDGLRDALDPKLKV
>Mature_304_residues
MQTELNKEVKVKKEKIESPWTVAFKRLKKNKLALGGLFILLVLVLISILGPMLYPHDHLTIDLVRTNQPPSAQHWLGTDE
SGRDVLARLMYGGRYSLSIGIVAVGISIIIGTTLGILAGYYGGFIDSLIMRIVDVFMCFPFLSLLIMVSAIMSDLKIPPE
YRIFVVMFIIGALSWTGTCRMVRGMVLSLREQEFMQAAEALGLSDARKMFLHLLPNTLAVIIVSATLGIGGAILTESSLS
FLGLGVTPPTPTWGNMIQTAQDYYTLTNRWWLWIPPGVCIFLTVISINIFGDGLRDALDPKLKV

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=303, Percent_Identity=38.9438943894389, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1787760, Length=275, Percent_Identity=38.1818181818182, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1787498, Length=308, Percent_Identity=36.3636363636364, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789964, Length=292, Percent_Identity=38.3561643835616, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1789889, Length=249, Percent_Identity=38.9558232931727, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1788505, Length=241, Percent_Identity=34.0248962655602, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1787549, Length=285, Percent_Identity=28.4210526315789, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33618; Mature: 33618

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTELNKEVKVKKEKIESPWTVAFKRLKKNKLALGGLFILLVLVLISILGPMLYPHDHLT
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IDLVRTNQPPSAQHWLGTDESGRDVLARLMYGGRYSLSIGIVAVGISIIIGTTLGILAGY
EEEEECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
YGGFIDSLIMRIVDVFMCFPFLSLLIMVSAIMSDLKIPPEYRIFVVMFIIGALSWTGTCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHH
MVRGMVLSLREQEFMQAAEALGLSDARKMFLHLLPNTLAVIIVSATLGIGGAILTESSLS
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHH
FLGLGVTPPTPTWGNMIQTAQDYYTLTNRWWLWIPPGVCIFLTVISINIFGDGLRDALDP
HEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCHHHHHCCC
KLKV
CCCC
>Mature Secondary Structure
MQTELNKEVKVKKEKIESPWTVAFKRLKKNKLALGGLFILLVLVLISILGPMLYPHDHLT
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IDLVRTNQPPSAQHWLGTDESGRDVLARLMYGGRYSLSIGIVAVGISIIIGTTLGILAGY
EEEEECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
YGGFIDSLIMRIVDVFMCFPFLSLLIMVSAIMSDLKIPPEYRIFVVMFIIGALSWTGTCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHH
MVRGMVLSLREQEFMQAAEALGLSDARKMFLHLLPNTLAVIIVSATLGIGGAILTESSLS
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHH
FLGLGVTPPTPTWGNMIQTAQDYYTLTNRWWLWIPPGVCIFLTVISINIFGDGLRDALDP
HEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCHHHHHCCC
KLKV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9680333 [H]