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The map label for this gene is atoC [C]

Identifier: 18309910

GI number: 18309910

Start: 1126690

End: 1127442

Strand: Direct

Name: atoC [C]

Synonym: CPE0928

Alternate gene names: 18309910

Gene position: 1126690-1127442 (Clockwise)

Preceding gene: 18309909

Following gene: 18309911

Centisome position: 37.17

GC content: 27.62

Gene sequence:

>753_bases
GTGTTTAGCATAATGGTTGCTGATGATGAACAATTAGAAAGAAGAGTTTTAACCTCTATATTAAAAAAGAATGTAAGAGT
TAAAGAAATTATTGAAGCAAAAAATGGAAAAGAAGCTTTAGAATTAAATAGAGAATTTAATCCAGATATAATAATAATGG
ATATAAAGATGCCAGGAATAAATGGCATTAAAGCCTTGGAGCTTATAAAAAATGAAAATCCTAATAAGGAAATAATAATG
CTTACAGCATATGATGATTTTGAGTTTATACACAAAGTTTTAGTGTTAGGAGGATCGGACTACATAATAAAACCAATAAA
ACCAGATAAACTAATGGAAATTGTTGATAATATTATGGATAAGATTGAAAATAAGAATATAGAATTAGGAGTAAAAAGTC
ATAGTGATGAAAAGACTCTAGATAGAAACTTAACAAATGAAGAGAAAATAGTAGATAAGGTTTCTAAGTATATTGATGAC
AATATGGATAAAATGCTGAAGTTAGAAGAATTAGCTTCAATCTGTAATTTAAGCCCAGGGTATTTTAGTAGGGTTTTTAA
AAAGGAAACTGGTAAAACCGTAATAACATATATAAATGAGAAGAAGGTAGAAAGAGCAAAGAAACTTTTAAAAGAAAGTA
AAGACCCTATAATCAATATATCCTTAGACTTAGGTTTTGATGATTGTGGATATTTTATAAGGGTATTCAAAAAGATAACA
GGCTTAACTCCTAAGGCCTTTAGAGAAGAATAA

Upstream 100 bases:

>100_bases
GGTGAAGAATATAGTATAAATATAGATAGTAAAGTTAAAAAAGGTACTAAAGTAGAAATTATAATACCTAGAAAACTTTA
AATAAAGGAAGTGTATTTTT

Downstream 100 bases:

>100_bases
TTAATTATTAAATTAACAAACATAAGATTTTTGTGAGAAATGTTACAGAAGAAAAAAATAATATAAGATAATATATTGTT
ATAAATAAAGCAACTTTTAT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MFSIMVADDEQLERRVLTSILKKNVRVKEIIEAKNGKEALELNREFNPDIIIMDIKMPGINGIKALELIKNENPNKEIIM
LTAYDDFEFIHKVLVLGGSDYIIKPIKPDKLMEIVDNIMDKIENKNIELGVKSHSDEKTLDRNLTNEEKIVDKVSKYIDD
NMDKMLKLEELASICNLSPGYFSRVFKKETGKTVITYINEKKVERAKKLLKESKDPIINISLDLGFDDCGYFIRVFKKIT
GLTPKAFREE

Sequences:

>Translated_250_residues
MFSIMVADDEQLERRVLTSILKKNVRVKEIIEAKNGKEALELNREFNPDIIIMDIKMPGINGIKALELIKNENPNKEIIM
LTAYDDFEFIHKVLVLGGSDYIIKPIKPDKLMEIVDNIMDKIENKNIELGVKSHSDEKTLDRNLTNEEKIVDKVSKYIDD
NMDKMLKLEELASICNLSPGYFSRVFKKETGKTVITYINEKKVERAKKLLKESKDPIINISLDLGFDDCGYFIRVFKKIT
GLTPKAFREE
>Mature_250_residues
MFSIMVADDEQLERRVLTSILKKNVRVKEIIEAKNGKEALELNREFNPDIIIMDIKMPGINGIKALELIKNENPNKEIIM
LTAYDDFEFIHKVLVLGGSDYIIKPIKPDKLMEIVDNIMDKIENKNIELGVKSHSDEKTLDRNLTNEEKIVDKVSKYIDD
NMDKMLKLEELASICNLSPGYFSRVFKKETGKTVITYINEKKVERAKKLLKESKDPIINISLDLGFDDCGYFIRVFKKIT
GLTPKAFREE

Specific function: Probable member of the two-component regulatory system SE_0166/SE_0165 [H]

COG id: COG4753

COG function: function code T; Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=150, Percent_Identity=32.6666666666667, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786251, Length=99, Percent_Identity=35.3535353535354, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=35.9649122807018, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788222, Length=118, Percent_Identity=28.8135593220339, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788030, Length=110, Percent_Identity=30, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081928, Length=92, Percent_Identity=32.6086956521739, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788521, Length=114, Percent_Identity=27.1929824561404, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=30.46875, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00165 HTH_AraC; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28831; Mature: 28831

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSIMVADDEQLERRVLTSILKKNVRVKEIIEAKNGKEALELNREFNPDIIIMDIKMPGI
CEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEECCCC
NGIKALELIKNENPNKEIIMLTAYDDFEFIHKVLVLGGSDYIIKPIKPDKLMEIVDNIMD
CCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
KIENKNIELGVKSHSDEKTLDRNLTNEEKIVDKVSKYIDDNMDKMLKLEELASICNLSPG
HHCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
YFSRVFKKETGKTVITYINEKKVERAKKLLKESKDPIINISLDLGFDDCGYFIRVFKKIT
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
GLTPKAFREE
CCCCHHHCCC
>Mature Secondary Structure
MFSIMVADDEQLERRVLTSILKKNVRVKEIIEAKNGKEALELNREFNPDIIIMDIKMPGI
CEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEECCCC
NGIKALELIKNENPNKEIIMLTAYDDFEFIHKVLVLGGSDYIIKPIKPDKLMEIVDNIMD
CCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
KIENKNIELGVKSHSDEKTLDRNLTNEEKIVDKVSKYIDDNMDKMLKLEELASICNLSPG
HHCCCCEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
YFSRVFKKETGKTVITYINEKKVERAKKLLKESKDPIINISLDLGFDDCGYFIRVFKKIT
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
GLTPKAFREE
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]