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The map label for this gene is prmA [H]

Identifier: 17547507

GI number: 17547507

Start: 2998586

End: 2999482

Strand: Direct

Name: prmA [H]

Synonym: RSc2788

Alternate gene names: 17547507

Gene position: 2998586-2999482 (Clockwise)

Preceding gene: 17547506

Following gene: 17547508

Centisome position: 80.68

GC content: 70.57

Gene sequence:

>897_bases
ATGACCTACCGCGAATGCGTGCTGGAAGTCGCGCGCGACGATGCCGAGGCGCTGTCCGAGGCGTTGTTCGACCTGGGTGC
GCTGTCGGTGTCGGTGGAAGACGCCGATGCCGACACGCCCGACGAGGAGCCCCTGTTCGGCGAGCCCGGCCACGAGCCGA
CGCGCCTGGCCTGGAACCGGTCCCGCGTGGTCGCCCTGCTGGGCGATGACGCCGACCCGGCGCTGCTGGTGGCCGCCGCG
GCCAATGCCATCGGCCTGTCCGCCGCGCCCGCCTACACCGTGCGCGAGGTCGAGGAGCAGGACTGGGTGCGCCTGACGCA
GTCGCAGTTCGAGCCGATCCATATCGGCGAGCACATCTGGGTGGTCCCTTCGTGGCACGATGCGCCGCAACCCGAGGCGG
TGGTGCTGGAGCTCGACCCCGGCCTCGCCTTCGGCACCGGCAGCCACCCGACCACGCGGCTGTGCATGGAATGGCTGGAG
CAACACGTCCAGCCCGGCGAGCGCACGCTGGACTACGGCTGCGGCTCGGGCATCCTCGCCATCGTCGCCAAGAAGCTCGG
CACGGGCGAAACCGTCGGCGTCGACATCGACCCGAACGCCGTGGAAGCCTCGCGCTACAACGCCGAGCGCAACCGCGTCG
AGGCCGGCTTCAGCCTGCCGGGCGATGCGCCCGAGGGCACGTTCGATCTGGTCGTCGCCAATATCCTGTCGAACCCGCTC
AAGCTGATGGCCTCGATGCTGTGCGCACGCGTGCGCCCGGGCGGAAGGCTCGTGCTGTCGGGCGTGCTGGAGCGCCAGGC
GGAAGACGTTGCCGCGGCGTATGCCGACGCGATCCCGCTGTCGGTGTGGCGCGCGCGTGACGGCTGGGTCTGCCTGCACG
GTGTGAAACCCGCATAA

Upstream 100 bases:

>100_bases
ACTTCGTCGAAGGCGGCACCAGCATCCACTACCTGGAGCACCGCCTGGCGCAGCAGGAAGTGGCCAAGGGCGGCGGCAAG
GCCTGAGCGGAACCGGACCC

Downstream 100 bases:

>100_bases
AAAGTGCGGCCCGGCGCGGCGAAAGGTCGACGCTGGGCCCATGGTCTGCAATACTCGCGCGGTCGGCTTTTTTCTCTCCA
ACCTGCATGGCATCCGCGCC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTYRECVLEVARDDAEALSEALFDLGALSVSVEDADADTPDEEPLFGEPGHEPTRLAWNRSRVVALLGDDADPALLVAAA
ANAIGLSAAPAYTVREVEEQDWVRLTQSQFEPIHIGEHIWVVPSWHDAPQPEAVVLELDPGLAFGTGSHPTTRLCMEWLE
QHVQPGERTLDYGCGSGILAIVAKKLGTGETVGVDIDPNAVEASRYNAERNRVEAGFSLPGDAPEGTFDLVVANILSNPL
KLMASMLCARVRPGGRLVLSGVLERQAEDVAAAYADAIPLSVWRARDGWVCLHGVKPA

Sequences:

>Translated_298_residues
MTYRECVLEVARDDAEALSEALFDLGALSVSVEDADADTPDEEPLFGEPGHEPTRLAWNRSRVVALLGDDADPALLVAAA
ANAIGLSAAPAYTVREVEEQDWVRLTQSQFEPIHIGEHIWVVPSWHDAPQPEAVVLELDPGLAFGTGSHPTTRLCMEWLE
QHVQPGERTLDYGCGSGILAIVAKKLGTGETVGVDIDPNAVEASRYNAERNRVEAGFSLPGDAPEGTFDLVVANILSNPL
KLMASMLCARVRPGGRLVLSGVLERQAEDVAAAYADAIPLSVWRARDGWVCLHGVKPA
>Mature_297_residues
TYRECVLEVARDDAEALSEALFDLGALSVSVEDADADTPDEEPLFGEPGHEPTRLAWNRSRVVALLGDDADPALLVAAAA
NAIGLSAAPAYTVREVEEQDWVRLTQSQFEPIHIGEHIWVVPSWHDAPQPEAVVLELDPGLAFGTGSHPTTRLCMEWLEQ
HVQPGERTLDYGCGSGILAIVAKKLGTGETVGVDIDPNAVEASRYNAERNRVEAGFSLPGDAPEGTFDLVVANILSNPLK
LMASMLCARVRPGGRLVLSGVLERQAEDVAAAYADAIPLSVWRARDGWVCLHGVKPA

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=299, Percent_Identity=43.8127090301003, Blast_Score=198, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32003; Mature: 31872

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRECVLEVARDDAEALSEALFDLGALSVSVEDADADTPDEEPLFGEPGHEPTRLAWNR
CCHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECC
SRVVALLGDDADPALLVAAAANAIGLSAAPAYTVREVEEQDWVRLTQSQFEPIHIGEHIW
CEEEEEECCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEE
VVPSWHDAPQPEAVVLELDPGLAFGTGSHPTTRLCMEWLEQHVQPGERTLDYGCGSGILA
EEECCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCHHHH
IVAKKLGTGETVGVDIDPNAVEASRYNAERNRVEAGFSLPGDAPEGTFDLVVANILSNPL
HHHHHCCCCCEEEEECCCCCHHHHHHCCHHHHEECCCCCCCCCCCCHHHHHHHHHHCCHH
KLMASMLCARVRPGGRLVLSGVLERQAEDVAAAYADAIPLSVWRARDGWVCLHGVKPA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCEEEEECCCCC
>Mature Secondary Structure 
TYRECVLEVARDDAEALSEALFDLGALSVSVEDADADTPDEEPLFGEPGHEPTRLAWNR
CHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECC
SRVVALLGDDADPALLVAAAANAIGLSAAPAYTVREVEEQDWVRLTQSQFEPIHIGEHIW
CEEEEEECCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEE
VVPSWHDAPQPEAVVLELDPGLAFGTGSHPTTRLCMEWLEQHVQPGERTLDYGCGSGILA
EEECCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCHHHH
IVAKKLGTGETVGVDIDPNAVEASRYNAERNRVEAGFSLPGDAPEGTFDLVVANILSNPL
HHHHHCCCCCEEEEECCCCCHHHHHHCCHHHHEECCCCCCCCCCCCHHHHHHHHHHCCHH
KLMASMLCARVRPGGRLVLSGVLERQAEDVAAAYADAIPLSVWRARDGWVCLHGVKPA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA