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The map label for this gene is ppiD [H]

Identifier: 17546434

GI number: 17546434

Start: 1833798

End: 1835744

Strand: Direct

Name: ppiD [H]

Synonym: RSc1715

Alternate gene names: 17546434

Gene position: 1833798-1835744 (Clockwise)

Preceding gene: 17546433

Following gene: 17546437

Centisome position: 49.34

GC content: 65.02

Gene sequence:

>1947_bases
ATGCTTGATTTCGTACGTACGCATCGGCGCTTGATGTTTCTGGTGCTGCTGATTCTGGTGTTTCCGTCGTTCGTGTTCTT
TGGTGTGCAGGGCTACTCGCGTTTCATGGATGGCTCGCACGACGCTGCCAAGGTGGGTGATACCGTCATCACCACCAGCG
AGCTCGATACGCGCGTCCGCGAGCAGACCGAGCGTCTGCGCCAGATGCTGGGCGCGCAGTACGATCCACGCCAGTTCGAG
GGCCCACAGATGCGCCGCGACGTGCTGGACGGCATCATCCAGCAGCGCGTGATGGTCAATGAGGCGTCGCGGGCCAATCT
GTCGGTGGCGGACAGCAAGGTCCGCGAGACCATCGAGCAGATCCCGGCGGTCGCGCAGCTGCGCAAGCCGGATGGGAAGT
TCGATACCGATGCCTACATCAAGCTGCTGGCCGCCCAGGGCATGACGCCGGAGCAGTTCGATGCGCGCCTGCGCTCGGAG
CTCGTGCTGCAGCAGATTCCGCAGTCGATCGTTTCGAGTGCCTTCGTGCCCAAGTCGCTGGTGGATCGCCTGATCGAGGC
GCGCGACCAGCAGCGTGAAGTGCAGGCGCTGCTGTTCAAGCCGGCCGATTACGCGGCCAAGGTGACGGTCGACGACAAGG
CCATCCAGGCTTACTACGACGCGCACCAGCAGGAATTCGCGGTGCTTGAGCAGGTCAAGGCCGAGTACGTGGTGTTTTCG
GGCGAGGAGATGATGAAGCAGATCCCCGTCACGCCCGAGCAGCTCAAGGAGTACTACGACCAGAACGCCGCGCGCTTCAA
GACCGAAGAGCAACGCCGCGCCGCGCACATCCTGATCAAGCTGCCGGACAACGCCAAGCCCGCCGATAAGGACGCAGCCA
AGAAGCGCGCGGAAGAGGTGCTGGCCGAAGTGCGCAAGAGCCCGGGCAGTTTCGCAGAGCTCGCCAAGAAGTATTCGGGG
GATCCGGGCTCGGCCGCGCAGGGCGGTGAGCTGGGCTTCCTCGCCAAGGGCGCGACCGTGCCGCCGTTCGAGAATGCACT
GTTTGCGCTCAAGCAGCCGGGCGATATCAGCGATGTGGTGGAGAGCGATTTCGGCTTCCACATCATCAAGCTGGAAGACG
TGAAGGGCGGTGGCGTGCAGTCGCTGGACGCCGTCAAGCCGGAGCTGGAGCGCGAGGTGCGCACGCAGTTGGCCAACAAG
AAGTACACCGAGCTGGCCGATGCCTTCTCCAACGGGGTGGAGGACCAGTCCGACAGCCTGAAGCCGGTCGCCGACAAGCT
CAAGCTGCAGATCCAGACGGCCGACCATGTCACGCGCGTGCCGAATCCGGCCCTGGGCAACAGCCCGGTCAACAACGAGA
AGGTGCTCAAGGCGCTGTTCGCCGACGACGTGACCAAGAACCATCGCAATACGCAGGCCGTGCAGGTCGGGCCGACCACG
CTGGTGGCGGCGCGTGCGGTGGAGTATCGGCCGGCCACGGTCAAGAAGCTGGCCGATGTGCGCGAGCAGGTGAAGGCCAA
AGTGCTGGCCGAGCAGTCGGCGGCGCTGGCCAAGAAGGCGGGCGAAGAGAAGCTTGCCGCGCTCAAGCAGAGCAACAGCG
CCGAGGGCTTTGGCACGGCGCAGACGCTCTCGCGCCAGCAGGCGCAGGGCACGCCGCCGGCCGCGCTGGTTGCGATCCTG
CGCGCGGATGCGGCCAAGCTGCCGGTCACCATCGGCGTGGATCTGGGGGCGCAGGGCTATGCGCTGTATCGCATCAACAA
GGTGCTGCCGCCGGCCAATGTGGACCCGGCGCGGCGAGCGGCCGATGCACAGCAACTGACGCAGGCAGCCGGACAGGCGG
ATTTCAACGCCTACTATGAAGCGCTGAAGGCGCGCTCGAAGGTGAAGATCAACGGCTCGGTGGTCGACGCCGCCAAGCCT
GCGGCTTCGTCGGACGACGGTTCCTGA

Upstream 100 bases:

>100_bases
GTGTCGCCGTGCCGGCGCATCGCGGCGAGATTCTCCGGCAAGCCCGCCGCACCTGATAGAATCGCCGGATTTTCCATCTT
CTCCTCGTCTCCGGTCCAGC

Downstream 100 bases:

>100_bases
GCGGTTCGGCAGGTACAAGAAAAAAGCCCCCTCGATGAGGGGGCTTTTTGTTATCGGCGCTCAGTCGAGCGGCCGGCCGA
TGCGCGCGAGGCGCGGCAGG

Product: peptidyl-prolyl cis-trans isomerase transmembrane protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MLDFVRTHRRLMFLVLLILVFPSFVFFGVQGYSRFMDGSHDAAKVGDTVITTSELDTRVREQTERLRQMLGAQYDPRQFE
GPQMRRDVLDGIIQQRVMVNEASRANLSVADSKVRETIEQIPAVAQLRKPDGKFDTDAYIKLLAAQGMTPEQFDARLRSE
LVLQQIPQSIVSSAFVPKSLVDRLIEARDQQREVQALLFKPADYAAKVTVDDKAIQAYYDAHQQEFAVLEQVKAEYVVFS
GEEMMKQIPVTPEQLKEYYDQNAARFKTEEQRRAAHILIKLPDNAKPADKDAAKKRAEEVLAEVRKSPGSFAELAKKYSG
DPGSAAQGGELGFLAKGATVPPFENALFALKQPGDISDVVESDFGFHIIKLEDVKGGGVQSLDAVKPELEREVRTQLANK
KYTELADAFSNGVEDQSDSLKPVADKLKLQIQTADHVTRVPNPALGNSPVNNEKVLKALFADDVTKNHRNTQAVQVGPTT
LVAARAVEYRPATVKKLADVREQVKAKVLAEQSAALAKKAGEEKLAALKQSNSAEGFGTAQTLSRQQAQGTPPAALVAIL
RADAAKLPVTIGVDLGAQGYALYRINKVLPPANVDPARRAADAQQLTQAAGQADFNAYYEALKARSKVKINGSVVDAAKP
AASSDDGS

Sequences:

>Translated_648_residues
MLDFVRTHRRLMFLVLLILVFPSFVFFGVQGYSRFMDGSHDAAKVGDTVITTSELDTRVREQTERLRQMLGAQYDPRQFE
GPQMRRDVLDGIIQQRVMVNEASRANLSVADSKVRETIEQIPAVAQLRKPDGKFDTDAYIKLLAAQGMTPEQFDARLRSE
LVLQQIPQSIVSSAFVPKSLVDRLIEARDQQREVQALLFKPADYAAKVTVDDKAIQAYYDAHQQEFAVLEQVKAEYVVFS
GEEMMKQIPVTPEQLKEYYDQNAARFKTEEQRRAAHILIKLPDNAKPADKDAAKKRAEEVLAEVRKSPGSFAELAKKYSG
DPGSAAQGGELGFLAKGATVPPFENALFALKQPGDISDVVESDFGFHIIKLEDVKGGGVQSLDAVKPELEREVRTQLANK
KYTELADAFSNGVEDQSDSLKPVADKLKLQIQTADHVTRVPNPALGNSPVNNEKVLKALFADDVTKNHRNTQAVQVGPTT
LVAARAVEYRPATVKKLADVREQVKAKVLAEQSAALAKKAGEEKLAALKQSNSAEGFGTAQTLSRQQAQGTPPAALVAIL
RADAAKLPVTIGVDLGAQGYALYRINKVLPPANVDPARRAADAQQLTQAAGQADFNAYYEALKARSKVKINGSVVDAAKP
AASSDDGS
>Mature_648_residues
MLDFVRTHRRLMFLVLLILVFPSFVFFGVQGYSRFMDGSHDAAKVGDTVITTSELDTRVREQTERLRQMLGAQYDPRQFE
GPQMRRDVLDGIIQQRVMVNEASRANLSVADSKVRETIEQIPAVAQLRKPDGKFDTDAYIKLLAAQGMTPEQFDARLRSE
LVLQQIPQSIVSSAFVPKSLVDRLIEARDQQREVQALLFKPADYAAKVTVDDKAIQAYYDAHQQEFAVLEQVKAEYVVFS
GEEMMKQIPVTPEQLKEYYDQNAARFKTEEQRRAAHILIKLPDNAKPADKDAAKKRAEEVLAEVRKSPGSFAELAKKYSG
DPGSAAQGGELGFLAKGATVPPFENALFALKQPGDISDVVESDFGFHIIKLEDVKGGGVQSLDAVKPELEREVRTQLANK
KYTELADAFSNGVEDQSDSLKPVADKLKLQIQTADHVTRVPNPALGNSPVNNEKVLKALFADDVTKNHRNTQAVQVGPTT
LVAARAVEYRPATVKKLADVREQVKAKVLAEQSAALAKKAGEEKLAALKQSNSAEGFGTAQTLSRQQAQGTPPAALVAIL
RADAAKLPVTIGVDLGAQGYALYRINKVLPPANVDPARRAADAQQLTQAAGQADFNAYYEALKARSKVKINGSVVDAAKP
AASSDDGS

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=646, Percent_Identity=29.1021671826625, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786238, Length=138, Percent_Identity=36.231884057971, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 70880; Mature: 70880

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFVRTHRRLMFLVLLILVFPSFVFFGVQGYSRFMDGSHDAAKVGDTVITTSELDTRVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEHHHHHHHHH
EQTERLRQMLGAQYDPRQFEGPQMRRDVLDGIIQQRVMVNEASRANLSVADSKVRETIEQ
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IPAVAQLRKPDGKFDTDAYIKLLAAQGMTPEQFDARLRSELVLQQIPQSIVSSAFVPKSL
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDRLIEARDQQREVQALLFKPADYAAKVTVDDKAIQAYYDAHQQEFAVLEQVKAEYVVFS
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GEEMMKQIPVTPEQLKEYYDQNAARFKTEEQRRAAHILIKLPDNAKPADKDAAKKRAEEV
CHHHHHHCCCCHHHHHHHHCCHHHHCCCHHHHCEEEEEEECCCCCCCCCHHHHHHHHHHH
LAEVRKSPGSFAELAKKYSGDPGSAAQGGELGFLAKGATVPPFENALFALKQPGDISDVV
HHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHH
ESDFGFHIIKLEDVKGGGVQSLDAVKPELEREVRTQLANKKYTELADAFSNGVEDQSDSL
HCCCCEEEEEEEECCCCCCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCH
KPVADKLKLQIQTADHVTRVPNPALGNSPVNNEKVLKALFADDVTKNHRNTQAVQVGPTT
HHHHHHHEEEEECHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHH
LVAARAVEYRPATVKKLADVREQVKAKVLAEQSAALAKKAGEEKLAALKQSNSAEGFGTA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
QTLSRQQAQGTPPAALVAILRADAAKLPVTIGVDLGAQGYALYRINKVLPPANVDPARRA
HHHHHHHHCCCCHHHHHHHHHHCHHHCCEEEEECCCCCCEEEEEEHHCCCCCCCCHHHHH
ADAQQLTQAAGQADFNAYYEALKARSKVKINGSVVDAAKPAASSDDGS
HHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MLDFVRTHRRLMFLVLLILVFPSFVFFGVQGYSRFMDGSHDAAKVGDTVITTSELDTRVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEHHHHHHHHH
EQTERLRQMLGAQYDPRQFEGPQMRRDVLDGIIQQRVMVNEASRANLSVADSKVRETIEQ
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IPAVAQLRKPDGKFDTDAYIKLLAAQGMTPEQFDARLRSELVLQQIPQSIVSSAFVPKSL
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDRLIEARDQQREVQALLFKPADYAAKVTVDDKAIQAYYDAHQQEFAVLEQVKAEYVVFS
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GEEMMKQIPVTPEQLKEYYDQNAARFKTEEQRRAAHILIKLPDNAKPADKDAAKKRAEEV
CHHHHHHCCCCHHHHHHHHCCHHHHCCCHHHHCEEEEEEECCCCCCCCCHHHHHHHHHHH
LAEVRKSPGSFAELAKKYSGDPGSAAQGGELGFLAKGATVPPFENALFALKQPGDISDVV
HHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHH
ESDFGFHIIKLEDVKGGGVQSLDAVKPELEREVRTQLANKKYTELADAFSNGVEDQSDSL
HCCCCEEEEEEEECCCCCCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCH
KPVADKLKLQIQTADHVTRVPNPALGNSPVNNEKVLKALFADDVTKNHRNTQAVQVGPTT
HHHHHHHEEEEECHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHH
LVAARAVEYRPATVKKLADVREQVKAKVLAEQSAALAKKAGEEKLAALKQSNSAEGFGTA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
QTLSRQQAQGTPPAALVAILRADAAKLPVTIGVDLGAQGYALYRINKVLPPANVDPARRA
HHHHHHHHCCCCHHHHHHHHHHCHHHCCEEEEECCCCCCEEEEEEHHCCCCCCCCHHHHH
ADAQQLTQAAGQADFNAYYEALKARSKVKINGSVVDAAKPAASSDDGS
HHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]