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The map label for this gene is hptG

Identifier: 17545709

GI number: 17545709

Start: 1041349

End: 1043271

Strand: Direct

Name: hptG

Synonym: RSc0990

Alternate gene names: 17545709

Gene position: 1041349-1043271 (Clockwise)

Preceding gene: 17545708

Following gene: 17545710

Centisome position: 28.02

GC content: 66.72

Gene sequence:

>1923_bases
ATGGGTGCACCGCACGAGAAGATGGCGTTCCAGGCAGAGGTCAAGCAGCTTCTGCATCTGATGATCCATTCCCTGTACAG
CAACAAGGAAATCTTTCTGCGCGAGCTGGTCTCCAACGCGTCCGACGCCGTGGACAAGCTGCGCTTCGAGGGCATCGCCG
ACCCATCGCTGCTCGAAGGCGGCGGCGAGCTGGGCATCCGCATCGGTTTCGATGCCCAGGCCCGCACCGTCACCATCGCC
GACAACGGCATCGGCATGAGCCGCGACGAGGCCATCCGCAACCTCGGCACCATCGCCCGCTCGGGCACGCGCGAGTTCTT
CAGCCAGCTCTCCGGCGATCAGCAGAAAGACGCGGCGCTGATCGGCCAGTTCGGGGTCGGCTTCTATTCGGCCTTCATCG
TCGCCGACCGCGTGACGGTGGAATCGCGCCGTGCGGGCGTGCCCGCCGCCGAAGGCGTGCGCTGGGAAAGCGCGGGCGAC
GGCGAGTTCACCGTCGATGCCATCGAGCGCGCCGAGCGCGGCACCACCATCACGCTGCACCTGCGCGAGGGCGAGGACGA
TTTCCTCTCCGCCTGGCGCCTGAAGTCCATCGTGCAGAAGTACTCGGACCACATCTCCCTGCCGATCGCGATGCGCAAGG
AGAGCTGGGACGAAGAGAAGAAAGAGATGGTCGCGCAGGACGAATGGGAGACCATCAACCAGGCCAGCGCCCTGTGGGCC
CGCCCGCGCGCCGACGTGACCGACGAGCAGTACATCGCCTTCTACCAGCACATCGCACACGAGCAGGGCCAGCCGCTGGC
GTGGACGCACAACCGCGTCGAAGGCCGCAGCGAATACACGCAGCTGCTGTACCTCCCGACCAACGCGCCGTTCGACCTGT
GGGACCGCGAGCGCCGCAGCGGCCTGAAGCTGTACGTCAAGCGCGTCTTCATCATGGACGACGCCGAACAGCTGCTGCCG
GCCTACCTGCGCTTCGTCAAGGGCGTGATCGACTCGGCCGACCTGCCGCTGAACGTCTCGCGCGAGATCCTGCAGGAGAG
CCGCGACGTGAAGGCCATCCGAGAGGGCTCGACCAAGCGCGTGCTGGGCATGCTCGAATCGATGGCCGACTCGGATGACG
CCGCCGAAAAGGACAAGTACGCCACCTTCTGGCAGCACTTCGGCCAGGTGCTCAAGGAAGGCCTCGGCGAAGACTTCGCC
AACAAGGACCGTATCGCCAAGCTGCTGCGCTTTGCTTCCACGCACAACGCAGGGGACGAGCAGACCGTCTCGCTGGCCGA
CTACATCGGCCGCATGAAGGACGGCCAGGACAAGATCTACTACGTGAGCGCCGAGAACTGGACGGCCGCCAAGTCCGGCC
CGCACCTGGAGGTGTTCCGCAAGAAGGGCGTGGAAGTGTTGCTGCTGACCGACCGCGTGGACGAATGGATGCTGTCGTTC
CTGCACGACTTCGAAGAGAAGGCGCTGGTGTCGGTCGCGCGCGGCGGGCTGGACCTCGGCGCGCTGGAAGACGAAGCCGA
GCGCGCCGAGCACGCCAAGGTGGAAGGCGAGTTCAAGCCGCTGGTGGACCGCGCCAAGGCGGTGCTGGCCGACAAGGCCA
AGGACGTGCGCATCACGCATCGCCTGACCGATTCGCCGTCGTGCCTGGTGGCCGACGAGGGCGACATCAGCGGCACGCTG
GCGCGCCTGCTCAAGCAGGCCGGCCAGAAGGCGCCCGACACCAAGCCCGTGCTGGAACTGAACCCGGCACACCCGCTGGT
GCGCAAGCTGGCGTTGCTCGAATCCGTCACCGGCGGCGAGGCCGACCGCGCTGCGTTCGAGGATCGCCTGCACGTGCTGT
TCGACCAGGCGCTGCTGGCCGAGGGCGGCTCGCTGGCCGATCCGGCCGACTACGTGCAGCGCGTCAACCGCCTGCTGGCC
TGA

Upstream 100 bases:

>100_bases
AAAACGGCTCCGCCGCCCCATCTCCAGTTCACGCGGACCGCCCGCTGGGTGCGGTCCGCTTCGCTTTCTCCATCACATCC
TTCGAACCAAGAGACACACC

Downstream 100 bases:

>100_bases
CGCCGCCATGGCCGAAGCCTTGCCCGACCTGCAGCGCGGACTGGCGCCGATCCTCGATGCCGAGGTTCGCGTGCTGGTGC
TCGGCAGCTTTCCGGGCGAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MGAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIADPSLLEGGGELGIRIGFDAQARTVTIA
DNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAALIGQFGVGFYSAFIVADRVTVESRRAGVPAAEGVRWESAGD
GEFTVDAIERAERGTTITLHLREGEDDFLSAWRLKSIVQKYSDHISLPIAMRKESWDEEKKEMVAQDEWETINQASALWA
RPRADVTDEQYIAFYQHIAHEQGQPLAWTHNRVEGRSEYTQLLYLPTNAPFDLWDRERRSGLKLYVKRVFIMDDAEQLLP
AYLRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKRVLGMLESMADSDDAAEKDKYATFWQHFGQVLKEGLGEDFA
NKDRIAKLLRFASTHNAGDEQTVSLADYIGRMKDGQDKIYYVSAENWTAAKSGPHLEVFRKKGVEVLLLTDRVDEWMLSF
LHDFEEKALVSVARGGLDLGALEDEAERAEHAKVEGEFKPLVDRAKAVLADKAKDVRITHRLTDSPSCLVADEGDISGTL
ARLLKQAGQKAPDTKPVLELNPAHPLVRKLALLESVTGGEADRAAFEDRLHVLFDQALLAEGGSLADPADYVQRVNRLLA

Sequences:

>Translated_640_residues
MGAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIADPSLLEGGGELGIRIGFDAQARTVTIA
DNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAALIGQFGVGFYSAFIVADRVTVESRRAGVPAAEGVRWESAGD
GEFTVDAIERAERGTTITLHLREGEDDFLSAWRLKSIVQKYSDHISLPIAMRKESWDEEKKEMVAQDEWETINQASALWA
RPRADVTDEQYIAFYQHIAHEQGQPLAWTHNRVEGRSEYTQLLYLPTNAPFDLWDRERRSGLKLYVKRVFIMDDAEQLLP
AYLRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKRVLGMLESMADSDDAAEKDKYATFWQHFGQVLKEGLGEDFA
NKDRIAKLLRFASTHNAGDEQTVSLADYIGRMKDGQDKIYYVSAENWTAAKSGPHLEVFRKKGVEVLLLTDRVDEWMLSF
LHDFEEKALVSVARGGLDLGALEDEAERAEHAKVEGEFKPLVDRAKAVLADKAKDVRITHRLTDSPSCLVADEGDISGTL
ARLLKQAGQKAPDTKPVLELNPAHPLVRKLALLESVTGGEADRAAFEDRLHVLFDQALLAEGGSLADPADYVQRVNRLLA
>Mature_639_residues
GAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIADPSLLEGGGELGIRIGFDAQARTVTIAD
NGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAALIGQFGVGFYSAFIVADRVTVESRRAGVPAAEGVRWESAGDG
EFTVDAIERAERGTTITLHLREGEDDFLSAWRLKSIVQKYSDHISLPIAMRKESWDEEKKEMVAQDEWETINQASALWAR
PRADVTDEQYIAFYQHIAHEQGQPLAWTHNRVEGRSEYTQLLYLPTNAPFDLWDRERRSGLKLYVKRVFIMDDAEQLLPA
YLRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKRVLGMLESMADSDDAAEKDKYATFWQHFGQVLKEGLGEDFAN
KDRIAKLLRFASTHNAGDEQTVSLADYIGRMKDGQDKIYYVSAENWTAAKSGPHLEVFRKKGVEVLLLTDRVDEWMLSFL
HDFEEKALVSVARGGLDLGALEDEAERAEHAKVEGEFKPLVDRAKAVLADKAKDVRITHRLTDSPSCLVADEGDISGTLA
RLLKQAGQKAPDTKPVLELNPAHPLVRKLALLESVTGGEADRAAFEDRLHVLFDQALLAEGGSLADPADYVQRVNRLLA

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=694, Percent_Identity=39.3371757925072, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI20149594, Length=691, Percent_Identity=38.0607814761216, Blast_Score=435, Evalue=1e-122,
Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=35.1477449455677, Blast_Score=355, Evalue=1e-97,
Organism=Homo sapiens, GI154146191, Length=419, Percent_Identity=36.0381861575179, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI153792590, Length=419, Percent_Identity=36.0381861575179, Blast_Score=259, Evalue=7e-69,
Organism=Escherichia coli, GI1786679, Length=637, Percent_Identity=58.0847723704867, Blast_Score=756, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=680, Percent_Identity=38.2352941176471, Blast_Score=452, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542208, Length=685, Percent_Identity=38.8321167883212, Blast_Score=425, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI115535205, Length=660, Percent_Identity=32.5757575757576, Blast_Score=320, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=440, Percent_Identity=34.7727272727273, Blast_Score=261, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=683, Percent_Identity=37.4816983894583, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6325016, Length=687, Percent_Identity=36.8267831149927, Blast_Score=439, Evalue=1e-124,
Organism=Drosophila melanogaster, GI17647529, Length=696, Percent_Identity=37.3563218390805, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=687, Percent_Identity=36.2445414847162, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24586016, Length=670, Percent_Identity=33.2835820895522, Blast_Score=339, Evalue=4e-93,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_RALSO (Q8Y0Q3)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519111.1
- ProteinModelPortal:   Q8Y0Q3
- GeneID:   1219799
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0990
- NMPDR:   fig|267608.1.peg.990
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   RSOL267608:RSC0990-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71408; Mature: 71277

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIADPSLLEG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
GGELGIRIGFDAQARTVTIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAAL
CCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IGQFGVGFYSAFIVADRVTVESRRAGVPAAEGVRWESAGDGEFTVDAIERAERGTTITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEECCCCCCCEEHHHHHHHCCCCEEEEE
LREGEDDFLSAWRLKSIVQKYSDHISLPIAMRKESWDEEKKEMVAQDEWETINQASALWA
EECCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RPRADVTDEQYIAFYQHIAHEQGQPLAWTHNRVEGRSEYTQLLYLPTNAPFDLWDRERRS
CCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHC
GLKLYVKRVFIMDDAEQLLPAYLRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKR
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VLGMLESMADSDDAAEKDKYATFWQHFGQVLKEGLGEDFANKDRIAKLLRFASTHNAGDE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
QTVSLADYIGRMKDGQDKIYYVSAENWTAAKSGPHLEVFRKKGVEVLLLTDRVDEWMLSF
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHH
LHDFEEKALVSVARGGLDLGALEDEAERAEHAKVEGEFKPLVDRAKAVLADKAKDVRITH
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEE
RLTDSPSCLVADEGDISGTLARLLKQAGQKAPDTKPVLELNPAHPLVRKLALLESVTGGE
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCC
ADRAAFEDRLHVLFDQALLAEGGSLADPADYVQRVNRLLA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GAPHEKMAFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAVDKLRFEGIADPSLLEG
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
GGELGIRIGFDAQARTVTIADNGIGMSRDEAIRNLGTIARSGTREFFSQLSGDQQKDAAL
CCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IGQFGVGFYSAFIVADRVTVESRRAGVPAAEGVRWESAGDGEFTVDAIERAERGTTITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEECCCCCCCEEHHHHHHHCCCCEEEEE
LREGEDDFLSAWRLKSIVQKYSDHISLPIAMRKESWDEEKKEMVAQDEWETINQASALWA
EECCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RPRADVTDEQYIAFYQHIAHEQGQPLAWTHNRVEGRSEYTQLLYLPTNAPFDLWDRERRS
CCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHC
GLKLYVKRVFIMDDAEQLLPAYLRFVKGVIDSADLPLNVSREILQESRDVKAIREGSTKR
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VLGMLESMADSDDAAEKDKYATFWQHFGQVLKEGLGEDFANKDRIAKLLRFASTHNAGDE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
QTVSLADYIGRMKDGQDKIYYVSAENWTAAKSGPHLEVFRKKGVEVLLLTDRVDEWMLSF
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHH
LHDFEEKALVSVARGGLDLGALEDEAERAEHAKVEGEFKPLVDRAKAVLADKAKDVRITH
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEE
RLTDSPSCLVADEGDISGTLARLLKQAGQKAPDTKPVLELNPAHPLVRKLALLESVTGGE
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCC
ADRAAFEDRLHVLFDQALLAEGGSLADPADYVQRVNRLLA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852