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The map label for this gene is murC [H]

Identifier: 17230209

GI number: 17230209

Start: 3311821

End: 3313164

Strand: Direct

Name: murC [H]

Synonym: alr2717

Alternate gene names: 17230209

Gene position: 3311821-3313164 (Clockwise)

Preceding gene: 17230204

Following gene: 17230210

Centisome position: 51.64

GC content: 43.82

Gene sequence:

>1344_bases
ATGGATGTGGGAAATAAAATCAAAGTTATAGATAGGCTGCGGTTGGGTTTTGCGGTGTTGGTGGCGAAAAGTGTCACGTT
TTTAGTGCGATCGCTCCGTCTCGGTGCTGCTAGTGTATTACCAGGGTCTATTGCCCGTCGGATTGAACCCCGGTTGCTGC
AATTATTGAGTCAGCAGGTGAAAAATGGGGTCATCATCATTGCTGGGACTAATGGTAAAACTACTACAGCGCTGCTGTTA
TGCACTATTTTAGAAAATAAAGGCTACCGTGTCTGCCATAACTCCACGGGTGCAAATCTAGAAAATGGGTTGATGACGGC
GTTGCTAGAAAGCACTAACCTGGTGGGGACGCTAGATGTGGATTATGCAATTCTGGAAGTGGATGAGAATATTGTTCCCA
GAGTCTTAAAACCACTCCAGCCACGAATTATTCTTTGTTTAAACCTGTTCCGCGACCAACTTGATAGGTACGGTGAAGTA
GACACCATCAGCAAGCGGTGGACGAAGGTTATTTCGACTCTTCCAACAGAAACGGTAGTCATTCCCAACGCTGATGACCC
GACTTTATCCCTTCTCGGTCAACAGTTACCCCAAAAGGTCTTGTTCTTCGGTTTAAATGAACCAGAACATTATTTAGAAG
CCATTCCTCACGCCGTTGATTCTATCTATTGTCCTCAATGTGGACATTCTTTAGATTACCAAGGTGTGTATTTATCCCAT
TTGGGAGATTTTACTTGTCCTAGTTGCGGATTTACTAAGAGTCAACCTGCTTTAGCCAGTAGGGAATGGTCACAAATTCT
CGTTGGTTTATACAACAAATACAACACCTTAGCCGCCACCACCGCCGCTATTGAATTAGGTGTAGATGAAACCACAATTA
GAGATACTATTAATAATTTCCAGGCGGCTTTTGGTCGTGCAGAAGATTTAGTGATTGATGGTAAGCGCGTCAGAATTTTA
TTATCAAAAAATCCTGTGGGGACAAATGAAACAATTCGCGTCGTCACTCAAAGCACAGATAAAACCACTTTATTAGTATT
AAACGATCGCACCCCAGATGGCACAGATGTATCTTGGATTTGGGACGTAGATACAGAAAAATTAGTGGAACGGGGAGGAA
CTTTAGTAGTAAGTGGCGATCGCGTCTATGATATGGCACTACGTCTACGTTATAGTGAAAAATCGCCCCATAGTAACCTA
AATTTAATTGTCGAAGCCGATTTACGTCAAGCGATCGCCACAGCCTTAGAACACACCCCAGTCACCGAAACCCTGCATAT
TCTCCCCACCTATTCCGCCATGCTAGAAGTGCGCGAAGTCCTCACAGGTAGGAAAATTCTGTAA

Upstream 100 bases:

>100_bases
ATAGCGCCTAGTGGGATCTGTGGGGAGTGTTGACTGTTGACCTTTGACCGTTGACTATGGACTATTGACTAATTACTAAT
GACTATTAATAAATTAGGGT

Downstream 100 bases:

>100_bases
CCCAGTCAACAGTCAACAGTCAACAGTCAACAATCCCCACAAATATGAATTCTCCACAATTAGAATTAACTATCGGTTGG
CTATATCCTACATTGATGAG

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDVGNKIKVIDRLRLGFAVLVAKSVTFLVRSLRLGAASVLPGSIARRIEPRLLQLLSQQVKNGVIIIAGTNGKTTTALLL
CTILENKGYRVCHNSTGANLENGLMTALLESTNLVGTLDVDYAILEVDENIVPRVLKPLQPRIILCLNLFRDQLDRYGEV
DTISKRWTKVISTLPTETVVIPNADDPTLSLLGQQLPQKVLFFGLNEPEHYLEAIPHAVDSIYCPQCGHSLDYQGVYLSH
LGDFTCPSCGFTKSQPALASREWSQILVGLYNKYNTLAATTAAIELGVDETTIRDTINNFQAAFGRAEDLVIDGKRVRIL
LSKNPVGTNETIRVVTQSTDKTTLLVLNDRTPDGTDVSWIWDVDTEKLVERGGTLVVSGDRVYDMALRLRYSEKSPHSNL
NLIVEADLRQAIATALEHTPVTETLHILPTYSAMLEVREVLTGRKIL

Sequences:

>Translated_447_residues
MDVGNKIKVIDRLRLGFAVLVAKSVTFLVRSLRLGAASVLPGSIARRIEPRLLQLLSQQVKNGVIIIAGTNGKTTTALLL
CTILENKGYRVCHNSTGANLENGLMTALLESTNLVGTLDVDYAILEVDENIVPRVLKPLQPRIILCLNLFRDQLDRYGEV
DTISKRWTKVISTLPTETVVIPNADDPTLSLLGQQLPQKVLFFGLNEPEHYLEAIPHAVDSIYCPQCGHSLDYQGVYLSH
LGDFTCPSCGFTKSQPALASREWSQILVGLYNKYNTLAATTAAIELGVDETTIRDTINNFQAAFGRAEDLVIDGKRVRIL
LSKNPVGTNETIRVVTQSTDKTTLLVLNDRTPDGTDVSWIWDVDTEKLVERGGTLVVSGDRVYDMALRLRYSEKSPHSNL
NLIVEADLRQAIATALEHTPVTETLHILPTYSAMLEVREVLTGRKIL
>Mature_447_residues
MDVGNKIKVIDRLRLGFAVLVAKSVTFLVRSLRLGAASVLPGSIARRIEPRLLQLLSQQVKNGVIIIAGTNGKTTTALLL
CTILENKGYRVCHNSTGANLENGLMTALLESTNLVGTLDVDYAILEVDENIVPRVLKPLQPRIILCLNLFRDQLDRYGEV
DTISKRWTKVISTLPTETVVIPNADDPTLSLLGQQLPQKVLFFGLNEPEHYLEAIPHAVDSIYCPQCGHSLDYQGVYLSH
LGDFTCPSCGFTKSQPALASREWSQILVGLYNKYNTLAATTAAIELGVDETTIRDTINNFQAAFGRAEDLVIDGKRVRIL
LSKNPVGTNETIRVVTQSTDKTTLLVLNDRTPDGTDVSWIWDVDTEKLVERGGTLVVSGDRVYDMALRLRYSEKSPHSNL
NLIVEADLRQAIATALEHTPVTETLHILPTYSAMLEVREVLTGRKIL

Specific function: Cell wall formation [H]

COG id: COG0769

COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49354; Mature: 49354

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS01011 FOLYLPOLYGLU_SYNT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVGNKIKVIDRLRLGFAVLVAKSVTFLVRSLRLGAASVLPGSIARRIEPRLLQLLSQQV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHCCHHHHHHHHHHH
KNGVIIIAGTNGKTTTALLLCTILENKGYRVCHNSTGANLENGLMTALLESTNLVGTLDV
HCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEC
DYAILEVDENIVPRVLKPLQPRIILCLNLFRDQLDRYGEVDTISKRWTKVISTLPTETVV
CEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEE
IPNADDPTLSLLGQQLPQKVLFFGLNEPEHYLEAIPHAVDSIYCPQCGHSLDYQGVYLSH
ECCCCCHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHH
LGDFTCPSCGFTKSQPALASREWSQILVGLYNKYNTLAATTAAIELGVDETTIRDTINNF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHH
QAAFGRAEDLVIDGKRVRILLSKNPVGTNETIRVVTQSTDKTTLLVLNDRTPDGTDVSWI
HHHHCCCCCEEECCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEEEE
WDVDTEKLVERGGTLVVSGDRVYDMALRLRYSEKSPHSNLNLIVEADLRQAIATALEHTP
EECCHHHHHHCCCEEEEECCCEEEEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCC
VTETLHILPTYSAMLEVREVLTGRKIL
CHHHEEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDVGNKIKVIDRLRLGFAVLVAKSVTFLVRSLRLGAASVLPGSIARRIEPRLLQLLSQQV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHCCHHHHHHHHHHH
KNGVIIIAGTNGKTTTALLLCTILENKGYRVCHNSTGANLENGLMTALLESTNLVGTLDV
HCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEC
DYAILEVDENIVPRVLKPLQPRIILCLNLFRDQLDRYGEVDTISKRWTKVISTLPTETVV
CEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEE
IPNADDPTLSLLGQQLPQKVLFFGLNEPEHYLEAIPHAVDSIYCPQCGHSLDYQGVYLSH
ECCCCCHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHH
LGDFTCPSCGFTKSQPALASREWSQILVGLYNKYNTLAATTAAIELGVDETTIRDTINNF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHH
QAAFGRAEDLVIDGKRVRILLSKNPVGTNETIRVVTQSTDKTTLLVLNDRTPDGTDVSWI
HHHHCCCCCEEECCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEEEE
WDVDTEKLVERGGTLVVSGDRVYDMALRLRYSEKSPHSNLNLIVEADLRQAIATALEHTP
EECCHHHHHHCCCEEEEECCCEEEEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCC
VTETLHILPTYSAMLEVREVLTGRKIL
CHHHEEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA