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The map label for this gene is pkn1 [H]

Identifier: 17230203

GI number: 17230203

Start: 3306935

End: 3308215

Strand: Direct

Name: pkn1 [H]

Synonym: alr2711

Alternate gene names: 17230203

Gene position: 3306935-3308215 (Clockwise)

Preceding gene: 17230202

Following gene: 17230204

Centisome position: 51.56

GC content: 43.56

Gene sequence:

>1281_bases
GTGTGGGAGAGGATTGTGATATCAAAATTGAAAGCATCTAGTGTGAAAGAGTTGATTGCTTTTGCTTTGGAGGAGTGTCG
CACTAAAACCCTAAGTTTATTTGTAGGTATGGATGCAGCTACATTCTGTTGTCAACCTCATGCTGATTTTAGTCCTGTGG
GTTGGCATTTGGGACATATTGCCTATATAGAATCTCTTTGGGTATTAGAACATAGTGCTGATTTACCATGCTTATTTCCC
CAATATCGTCAGTTATTCGCAGCTGATGGTTTACCGAAAAAACAACGAGGCCAATTACCAGAAATAGCAGAAATCGTTTA
TTACTTGGATACAGTGAGAGCAAAGGTTTTGGAATATCTAGAAGTAGCTGATATCCAACAGCAAGAACGACTTTGGCGCT
TTTTAATTCAGCACGAAAGCCAACACTGCGAAATCATAACTATGGTGTTGGAATTACTTAACTGTCAACTGCCAACTGTC
AACTGTCAACTATCAACCGTCAACCATCAACAGTTAAATTCTGTGGGGGAGATGGTGGAAATTCCCGCAGGGGAGTTTGA
GTTGGGTAACGATTCCATTGATGCTTTAGATAATGAGCGTCCAGCACATAGAGTTTATTTAGATACTTACTGGATTGACC
GTTACCCTGTGACGTGTGGTGAATATGGGGTATTTATAGAGGCTGGAGGGTATCAAAACCCTGAATGGTGGTCAGTAGCA
GGTTGGAAATGGTTACAAACAGAGCAAGTAATACAACCACTTTACTGGAATCGCCTAAGCTCTACCACGGAGAATCACCC
AGTATATGGTGTTAGTTGGTACGAAGCCGAAGCTTATGCGCGGTTCGTCGGTAAGCGTTTACCCACAGAAGTTGAATGGG
AAAAAGCCGCAAGTTGGAATGTCAAAGCTGACTGTCGCCACACCTACCCTTGGGGGGAAGATATGCCAACACCCCAGAAT
TGTAATTGTGATGGACTACGACGAGGTTTAGGCGAGAAAACCACACCAGTCAATGCTTACCCGGCTGGGCAAAGTGCCTA
TGGTATATATGACACTTTAGGAAATGTTTGGGAGTGGACAGCTTCTTGGTTCGATGGTTACAAAGGTTTTCAAAGTTACC
CATACAAAGGTTACGCGCAAGTTTATTTTGACCAAAAACATCGCGTGTTAAAAGGTGGTAGTTGGGCAACACGTCCTTGG
GTACTGCGTCCTAGTTTCCGCAATTGGTATCATCCCCAGGTTCGTCAGATTTTTGCTGGGTTTCGTTGTGCGAGGGATTA
G

Upstream 100 bases:

>100_bases
TGGCTCAAAGATGATTTAACTTTTCCTAATTCTGTCATTATTGCATCTGAACCATTATTTGCAGGTAATTGGACTGCTTG
TCCAGAAAATAGCATTATCA

Downstream 100 bases:

>100_bases
GGACGAATCAATTCAAAATTCGTTGTGGAAAGTTGAGCTATTGTGTTGGTGTTTATGTAGCCTCTTCTAACGGAGAGGCT
ACATGGTTTTGGGAGTTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MWERIVISKLKASSVKELIAFALEECRTKTLSLFVGMDAATFCCQPHADFSPVGWHLGHIAYIESLWVLEHSADLPCLFP
QYRQLFAADGLPKKQRGQLPEIAEIVYYLDTVRAKVLEYLEVADIQQQERLWRFLIQHESQHCEIITMVLELLNCQLPTV
NCQLSTVNHQQLNSVGEMVEIPAGEFELGNDSIDALDNERPAHRVYLDTYWIDRYPVTCGEYGVFIEAGGYQNPEWWSVA
GWKWLQTEQVIQPLYWNRLSSTTENHPVYGVSWYEAEAYARFVGKRLPTEVEWEKAASWNVKADCRHTYPWGEDMPTPQN
CNCDGLRRGLGEKTTPVNAYPAGQSAYGIYDTLGNVWEWTASWFDGYKGFQSYPYKGYAQVYFDQKHRVLKGGSWATRPW
VLRPSFRNWYHPQVRQIFAGFRCARD

Sequences:

>Translated_426_residues
MWERIVISKLKASSVKELIAFALEECRTKTLSLFVGMDAATFCCQPHADFSPVGWHLGHIAYIESLWVLEHSADLPCLFP
QYRQLFAADGLPKKQRGQLPEIAEIVYYLDTVRAKVLEYLEVADIQQQERLWRFLIQHESQHCEIITMVLELLNCQLPTV
NCQLSTVNHQQLNSVGEMVEIPAGEFELGNDSIDALDNERPAHRVYLDTYWIDRYPVTCGEYGVFIEAGGYQNPEWWSVA
GWKWLQTEQVIQPLYWNRLSSTTENHPVYGVSWYEAEAYARFVGKRLPTEVEWEKAASWNVKADCRHTYPWGEDMPTPQN
CNCDGLRRGLGEKTTPVNAYPAGQSAYGIYDTLGNVWEWTASWFDGYKGFQSYPYKGYAQVYFDQKHRVLKGGSWATRPW
VLRPSFRNWYHPQVRQIFAGFRCARD
>Mature_426_residues
MWERIVISKLKASSVKELIAFALEECRTKTLSLFVGMDAATFCCQPHADFSPVGWHLGHIAYIESLWVLEHSADLPCLFP
QYRQLFAADGLPKKQRGQLPEIAEIVYYLDTVRAKVLEYLEVADIQQQERLWRFLIQHESQHCEIITMVLELLNCQLPTV
NCQLSTVNHQQLNSVGEMVEIPAGEFELGNDSIDALDNERPAHRVYLDTYWIDRYPVTCGEYGVFIEAGGYQNPEWWSVA
GWKWLQTEQVIQPLYWNRLSSTTENHPVYGVSWYEAEAYARFVGKRLPTEVEWEKAASWNVKADCRHTYPWGEDMPTPQN
CNCDGLRRGLGEKTTPVNAYPAGQSAYGIYDTLGNVWEWTASWFDGYKGFQSYPYKGYAQVYFDQKHRVLKGGSWATRPW
VLRPSFRNWYHPQVRQIFAGFRCARD

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=272, Percent_Identity=33.0882352941176, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI257470975, Length=274, Percent_Identity=32.4817518248175, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI194248088, Length=287, Percent_Identity=31.7073170731707, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38202250, Length=299, Percent_Identity=29.7658862876254, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI257470977, Length=295, Percent_Identity=27.7966101694915, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI226437577, Length=173, Percent_Identity=39.8843930635838, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194248090, Length=203, Percent_Identity=30.5418719211823, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130397, Length=298, Percent_Identity=27.1812080536913, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 49355; Mature: 49355

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWERIVISKLKASSVKELIAFALEECRTKTLSLFVGMDAATFCCQPHADFSPVGWHLGHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHEEECCCCCCCCCCHHHHHH
AYIESLWVLEHSADLPCLFPQYRQLFAADGLPKKQRGQLPEIAEIVYYLDTVRAKVLEYL
HHHHHHHHEECCCCCCEECHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EVADIQQQERLWRFLIQHESQHCEIITMVLELLNCQLPTVNCQLSTVNHQQLNSVGEMVE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHEEE
IPAGEFELGNDSIDALDNERPAHRVYLDTYWIDRYPVTCGEYGVFIEAGGYQNPEWWSVA
CCCCCEECCCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCEEEC
GWKWLQTEQVIQPLYWNRLSSTTENHPVYGVSWYEAEAYARFVGKRLPTEVEWEKAASWN
CCEECCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHCCCCC
VKADCRHTYPWGEDMPTPQNCNCDGLRRGLGEKTTPVNAYPAGQSAYGIYDTLGNVWEWT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ASWFDGYKGFQSYPYKGYAQVYFDQKHRVLKGGSWATRPWVLRPSFRNWYHPQVRQIFAG
HHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCCEEECCCHHCCCCHHHHHHHHH
FRCARD
HHHCCC
>Mature Secondary Structure
MWERIVISKLKASSVKELIAFALEECRTKTLSLFVGMDAATFCCQPHADFSPVGWHLGHI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHEEECCCCCCCCCCHHHHHH
AYIESLWVLEHSADLPCLFPQYRQLFAADGLPKKQRGQLPEIAEIVYYLDTVRAKVLEYL
HHHHHHHHEECCCCCCEECHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EVADIQQQERLWRFLIQHESQHCEIITMVLELLNCQLPTVNCQLSTVNHQQLNSVGEMVE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHEEE
IPAGEFELGNDSIDALDNERPAHRVYLDTYWIDRYPVTCGEYGVFIEAGGYQNPEWWSVA
CCCCCEECCCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCEEEC
GWKWLQTEQVIQPLYWNRLSSTTENHPVYGVSWYEAEAYARFVGKRLPTEVEWEKAASWN
CCEECCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHCCCCC
VKADCRHTYPWGEDMPTPQNCNCDGLRRGLGEKTTPVNAYPAGQSAYGIYDTLGNVWEWT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ASWFDGYKGFQSYPYKGYAQVYFDQKHRVLKGGSWATRPWVLRPSFRNWYHPQVRQIFAG
HHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCCEEECCCHHCCCCHHHHHHHHH
FRCARD
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]