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The map label for this gene is fadD21 [H]

Identifier: 17230170

GI number: 17230170

Start: 3248682

End: 3252302

Strand: Direct

Name: fadD21 [H]

Synonym: alr2678

Alternate gene names: 17230170

Gene position: 3248682-3252302 (Clockwise)

Preceding gene: 17230161

Following gene: 17230171

Centisome position: 50.65

GC content: 45.02

Gene sequence:

>3621_bases
ATGATTAACCGCCAACGACAAATATTGTCATTAACTCCACACCATGCAGCGACACTTGTGGATGTCTTACGCGCATGGAC
GCAGCAAAAAGGTGATGCGGTTGGTTTTGCTTTTTGGCAAGATGACAAACAGGTACATCTTACATACACGGAGTTAGACC
ACAAAGCGCGAGCCATTGCAGTGCATTTACAAGCTATGCGCTGGCAGGGAGAACGTGTATTATTAATGTATCCGCCAGGG
TTGGAATTGATTGCAGCTCTTATGGGTTGCTTTTATGCGGGTTTGGTGGCAGTTCCTGTATATCCTCCGCGTCCCAATAA
TAACATAACGAGGTTGTTGTCAATTGGTGAAGATGCCCAAGCTAAGGGAATTTTGACGAAAGTATCCTTAGAAAATTCTT
TAAAACAAGTATCTAAAAATACTGCTTTTGAGGCTTTGCCGAAAGTTGCTACAGATAGCATCATTTTATCTGTCGGTGAA
GCTTGGCAGAATCCTCAACTGACAGCCGATAGTCTGGCTTTACTACAATATACTTCTGGTTCGACCGGCACACCAAAGGG
CGTGATGCTGAGTCATGGTAATTTGCTGCATAACTTAGGGCAAATTTATCAACGTTTTGGACATTCTGCTAATACTCACG
TTGTCAGTTGGTTGCCACCTTATCATGACATGGGTTTGATTGGCGGAATTTTGCAGCCTTTATATGGAGGTTTTCCCGTC
ACTTTGATGTCTCCTGTAGCTTTTCTACAAAAACCCCTGCGTTGGTTACAAGCAATTTCTCAAACTCAAGCTACCACAAG
CGGCGCACCCAATTTCGCCTATGAAATGTGTGTCCGCAATATCCGTCTTGATGAATGTCTTGATTTAGATTTGAGTAGTT
GGGAGTTGGCGTTTACAGGTGCAGAACCAATTCGCCAGGAGACACTAGAAAGATTTGCTACTACTTTTAAAACTTATGGT
TTTCGTCGAGAAGCGTTTTATCCTTGCTATGGTTTAGCTGAGGCGACTTTGTTTGTCACTGGTAAAAATAAGGATGAAAT
AGTATTTAATCATACTTCTCAATCCTTGGTTAGTTGTGGTTCTCCCAGTGATGACCAGACTATAATTATAGTTAATCCTG
AATCTAGAGAACCCTGTGCAGCCGGGGAAGAAGGGGAAATTTGGCTCAAAGGTGCAAGTGTCGCCCAAGGTTATTGGCAA
AATCCCCAAGAAACAAAAGCAACTTTTCAAGGGGCTTTGGCTTCGGGAACTGGCGGGTTTTTACGCACGGGTGACTTGGG
GTATTTAAACTCAGGCGAATTATTTGTCACCGGCAGGATAAAAGATGTGATGATAATTCGGGGACAAAATTACTATCCTC
ACGATATTGAGGCGGCTGTTTCCCAGTGTCATCCGGCTTTGAGTGCCTATTGGGGTGCGGCGTTTAGTGTGGAAGTAGAC
GGGGAAGAACGGTTGGTGGTGGTGCAGGAGGTTGAACGTAGTAGTTGGCGTAGGCTTGATGAGGATGGGATTATTGCGGC
GATTCGTGGTGCTGTTTCCTGTGAGTTTGGTTTGCAGGTGTATGGGATTTGTTTGTTGAAGCCTGGGAGTATTCCTAAGA
CTTCTAGTGGGAAGGTGCAGCGTTTTGCTTGTCGGGAGGGGTTTGTTTGTGGGGGGTTGGATGTGGTGTTTGGGTGGGAA
TTAGCTCACGCAGAGGCGCAGAGGCGCAGAGAGGAGAGGGGAGAAGAGAAAGAAAAGATAGTAGATGGGTTGATTGGGTG
GTTACGGGATTATGCTAACCATCATATTAATTCGCGGTTGATGGATGAACGGCGTTGTATTTCGCCTCATGTGGTTTTGG
ATTTTGGGAATAAGGGTTTGTTGGGGATGCAAGTCCCTTCCTGTTATGGTGGGTTGGGTTTGGGATATACGGACACCATC
AGGATTATACAACAGCTTGGGGCGATTGATCCGACTTTGGCTTTGTTTGTGGGGTTGAATAATGTTTTGGGGGTGCGTCC
TATATTAATGTATGGGACGGATGCTTTAAAGGCGGAACTTTTACCGATTTTGGCGACGGGGCGGGAATTGGCAGCTTTTG
CACTGACGGAAACGGGTGCTGGGGCGAATCCGCAAGCTATACAGTCGCAAGCGATTAGTGATGGTGATGGTTGGTTGTTG
CGGGGGGAAAAGATTTGGAGTGGTTCGGCGGCTTGGGCTGGTGTGATTAATGTGTTTGTCAAACATCAGCAGGGTATTAG
CGGTTTTGTGGTGCGTCGCGGTAGTCCTGGTTTGCGTCAAGGTGCGGAAGCGTTGACGATGGGAATGCGGGGAATGGTAC
AGAATACGGTTTATTTGGAAGATATTCCGGTGACATCCGCGCAAGTTTTGGGTGAAGTCGGGAAGGGGATGAATGTCGCT
CAAGATGCCATGATGTATGGGAGATTAGCGATCGCATCTGCTTGTGTCGGTGGGATGCAACGCTGTGTACAATTAATGTG
GCGTTATAGTCAACGGCGACAAATCGCTACAGGGAAGTTACTCGACCATCCCATAGTTTTACATCGTCTGCAAGAATTGA
CTTGTGCGATTACTGTTGTCCAGAGTTTGGTGATGCGGGTAGGAAAATTACTCGACGCTGGTGAAACTGTGCCGGCGGAA
GTATATGCAGCTTGTAAAATTTCTGCACCGGAATTTTATTGGCAAGCAGCAGATTTATTGGTACAAACTTTAGGGGGACG
AGGATATATAGAAAGTAATATTGCACCGCAAATTCTCAGAGATGCGCGAGTTTTGCGGATATTTGAAGGGCCGACAGAAA
CTTTGTGTGGGTTTTTGGGTGCGCGTGTGTTGAAACAGGGTGAGACATTGCAAAATTTCCTCTGTCAAACTTTGGGTGCG
GTGGAAGTCGGTACGAGGTTAAGGGATGCTGTTGATAAAATTAGAGGACGCTGTTTTGATGGTGCTAATATTACAGTGCA
GCGTTGGGTTTATCATCAAGTCGGTAAACTCGCAACTGAAGCGATATTATGGGCAGTATTAGATGATAAATCTGCAATAA
ATTGGGTAAAACATCGCTTTGATGAACAACTGCAAGAAATCTTGAGTTTTAACACCGATAACTTACTATTTCTCAATGGT
CAAAGTTTAGTTCATCACCTCAACGAATACACAAAAACCATCGGTGACATTGAACAAAATCTGGCTGGGGAAGCGCAAGA
GTTAGATGAGTTACTGCGTCAGTCAGGGGAGAATCCCCAGTTTATTCCCACAACAGCAGATTTACCCGCATCCTCAGAGA
TTCAAACCTGGTTAAAAACTTGGATATCTCAAAAATTACGCCAGCCAATTTCTACTATAGATGTAAATAGAGCCTTCGCC
GAATACGGTATGGATTCCGTCACAGCGATAGAACTAACCCAAGATTTACAAGAATGGTTGAAGATTTCCCAACCTTTAGA
TGCGACTATCGCTTGGAATTTCCCCACCATTAACGCCTTAGCTAACTACTTGGGGGAAGTTACCAAAGAAAATGCTGTAC
CTTCAGATAACAACTTGGATGACTTATCTACTACAGATATAGCACAACTCTTAAGCCAAGAAATTGCGATCGCTCGTCAC
CGTAAACCTCAAATGAAATGA

Upstream 100 bases:

>100_bases
CCACACCCAAATGTAACTGCCAAGAAGCGCAGTTAAAAAGTGCAAATTTTTCACAAACCCTTCTAGCTAATTTCATTCCC
CCAAGGCGAATTGGTGCATA

Downstream 100 bases:

>100_bases
TCACGCCCAGACGCAGAGGCGCAGAGAGTGAGAGTTACAACAGACTCCGCGCCCCTTTGCGTTTACCTCCGCGCCCCTTT
GCGTTTAAAAAATCCTATGA

Product: hypothetical protein

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Acyl-CoA synthetase [H]

Number of amino acids: Translated: 1206; Mature: 1206

Protein sequence:

>1206_residues
MINRQRQILSLTPHHAATLVDVLRAWTQQKGDAVGFAFWQDDKQVHLTYTELDHKARAIAVHLQAMRWQGERVLLMYPPG
LELIAALMGCFYAGLVAVPVYPPRPNNNITRLLSIGEDAQAKGILTKVSLENSLKQVSKNTAFEALPKVATDSIILSVGE
AWQNPQLTADSLALLQYTSGSTGTPKGVMLSHGNLLHNLGQIYQRFGHSANTHVVSWLPPYHDMGLIGGILQPLYGGFPV
TLMSPVAFLQKPLRWLQAISQTQATTSGAPNFAYEMCVRNIRLDECLDLDLSSWELAFTGAEPIRQETLERFATTFKTYG
FRREAFYPCYGLAEATLFVTGKNKDEIVFNHTSQSLVSCGSPSDDQTIIIVNPESREPCAAGEEGEIWLKGASVAQGYWQ
NPQETKATFQGALASGTGGFLRTGDLGYLNSGELFVTGRIKDVMIIRGQNYYPHDIEAAVSQCHPALSAYWGAAFSVEVD
GEERLVVVQEVERSSWRRLDEDGIIAAIRGAVSCEFGLQVYGICLLKPGSIPKTSSGKVQRFACREGFVCGGLDVVFGWE
LAHAEAQRRREERGEEKEKIVDGLIGWLRDYANHHINSRLMDERRCISPHVVLDFGNKGLLGMQVPSCYGGLGLGYTDTI
RIIQQLGAIDPTLALFVGLNNVLGVRPILMYGTDALKAELLPILATGRELAAFALTETGAGANPQAIQSQAISDGDGWLL
RGEKIWSGSAAWAGVINVFVKHQQGISGFVVRRGSPGLRQGAEALTMGMRGMVQNTVYLEDIPVTSAQVLGEVGKGMNVA
QDAMMYGRLAIASACVGGMQRCVQLMWRYSQRRQIATGKLLDHPIVLHRLQELTCAITVVQSLVMRVGKLLDAGETVPAE
VYAACKISAPEFYWQAADLLVQTLGGRGYIESNIAPQILRDARVLRIFEGPTETLCGFLGARVLKQGETLQNFLCQTLGA
VEVGTRLRDAVDKIRGRCFDGANITVQRWVYHQVGKLATEAILWAVLDDKSAINWVKHRFDEQLQEILSFNTDNLLFLNG
QSLVHHLNEYTKTIGDIEQNLAGEAQELDELLRQSGENPQFIPTTADLPASSEIQTWLKTWISQKLRQPISTIDVNRAFA
EYGMDSVTAIELTQDLQEWLKISQPLDATIAWNFPTINALANYLGEVTKENAVPSDNNLDDLSTTDIAQLLSQEIAIARH
RKPQMK

Sequences:

>Translated_1206_residues
MINRQRQILSLTPHHAATLVDVLRAWTQQKGDAVGFAFWQDDKQVHLTYTELDHKARAIAVHLQAMRWQGERVLLMYPPG
LELIAALMGCFYAGLVAVPVYPPRPNNNITRLLSIGEDAQAKGILTKVSLENSLKQVSKNTAFEALPKVATDSIILSVGE
AWQNPQLTADSLALLQYTSGSTGTPKGVMLSHGNLLHNLGQIYQRFGHSANTHVVSWLPPYHDMGLIGGILQPLYGGFPV
TLMSPVAFLQKPLRWLQAISQTQATTSGAPNFAYEMCVRNIRLDECLDLDLSSWELAFTGAEPIRQETLERFATTFKTYG
FRREAFYPCYGLAEATLFVTGKNKDEIVFNHTSQSLVSCGSPSDDQTIIIVNPESREPCAAGEEGEIWLKGASVAQGYWQ
NPQETKATFQGALASGTGGFLRTGDLGYLNSGELFVTGRIKDVMIIRGQNYYPHDIEAAVSQCHPALSAYWGAAFSVEVD
GEERLVVVQEVERSSWRRLDEDGIIAAIRGAVSCEFGLQVYGICLLKPGSIPKTSSGKVQRFACREGFVCGGLDVVFGWE
LAHAEAQRRREERGEEKEKIVDGLIGWLRDYANHHINSRLMDERRCISPHVVLDFGNKGLLGMQVPSCYGGLGLGYTDTI
RIIQQLGAIDPTLALFVGLNNVLGVRPILMYGTDALKAELLPILATGRELAAFALTETGAGANPQAIQSQAISDGDGWLL
RGEKIWSGSAAWAGVINVFVKHQQGISGFVVRRGSPGLRQGAEALTMGMRGMVQNTVYLEDIPVTSAQVLGEVGKGMNVA
QDAMMYGRLAIASACVGGMQRCVQLMWRYSQRRQIATGKLLDHPIVLHRLQELTCAITVVQSLVMRVGKLLDAGETVPAE
VYAACKISAPEFYWQAADLLVQTLGGRGYIESNIAPQILRDARVLRIFEGPTETLCGFLGARVLKQGETLQNFLCQTLGA
VEVGTRLRDAVDKIRGRCFDGANITVQRWVYHQVGKLATEAILWAVLDDKSAINWVKHRFDEQLQEILSFNTDNLLFLNG
QSLVHHLNEYTKTIGDIEQNLAGEAQELDELLRQSGENPQFIPTTADLPASSEIQTWLKTWISQKLRQPISTIDVNRAFA
EYGMDSVTAIELTQDLQEWLKISQPLDATIAWNFPTINALANYLGEVTKENAVPSDNNLDDLSTTDIAQLLSQEIAIARH
RKPQMK
>Mature_1206_residues
MINRQRQILSLTPHHAATLVDVLRAWTQQKGDAVGFAFWQDDKQVHLTYTELDHKARAIAVHLQAMRWQGERVLLMYPPG
LELIAALMGCFYAGLVAVPVYPPRPNNNITRLLSIGEDAQAKGILTKVSLENSLKQVSKNTAFEALPKVATDSIILSVGE
AWQNPQLTADSLALLQYTSGSTGTPKGVMLSHGNLLHNLGQIYQRFGHSANTHVVSWLPPYHDMGLIGGILQPLYGGFPV
TLMSPVAFLQKPLRWLQAISQTQATTSGAPNFAYEMCVRNIRLDECLDLDLSSWELAFTGAEPIRQETLERFATTFKTYG
FRREAFYPCYGLAEATLFVTGKNKDEIVFNHTSQSLVSCGSPSDDQTIIIVNPESREPCAAGEEGEIWLKGASVAQGYWQ
NPQETKATFQGALASGTGGFLRTGDLGYLNSGELFVTGRIKDVMIIRGQNYYPHDIEAAVSQCHPALSAYWGAAFSVEVD
GEERLVVVQEVERSSWRRLDEDGIIAAIRGAVSCEFGLQVYGICLLKPGSIPKTSSGKVQRFACREGFVCGGLDVVFGWE
LAHAEAQRRREERGEEKEKIVDGLIGWLRDYANHHINSRLMDERRCISPHVVLDFGNKGLLGMQVPSCYGGLGLGYTDTI
RIIQQLGAIDPTLALFVGLNNVLGVRPILMYGTDALKAELLPILATGRELAAFALTETGAGANPQAIQSQAISDGDGWLL
RGEKIWSGSAAWAGVINVFVKHQQGISGFVVRRGSPGLRQGAEALTMGMRGMVQNTVYLEDIPVTSAQVLGEVGKGMNVA
QDAMMYGRLAIASACVGGMQRCVQLMWRYSQRRQIATGKLLDHPIVLHRLQELTCAITVVQSLVMRVGKLLDAGETVPAE
VYAACKISAPEFYWQAADLLVQTLGGRGYIESNIAPQILRDARVLRIFEGPTETLCGFLGARVLKQGETLQNFLCQTLGA
VEVGTRLRDAVDKIRGRCFDGANITVQRWVYHQVGKLATEAILWAVLDDKSAINWVKHRFDEQLQEILSFNTDNLLFLNG
QSLVHHLNEYTKTIGDIEQNLAGEAQELDELLRQSGENPQFIPTTADLPASSEIQTWLKTWISQKLRQPISTIDVNRAFA
EYGMDSVTAIELTQDLQEWLKISQPLDATIAWNFPTINALANYLGEVTKENAVPSDNNLDDLSTTDIAQLLSQEIAIARH
RKPQMK

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=422, Percent_Identity=28.6729857819905, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI4557235, Length=333, Percent_Identity=30.9309309309309, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI76496475, Length=333, Percent_Identity=30.9309309309309, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI4501859, Length=337, Percent_Identity=29.673590504451, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI44888818, Length=567, Percent_Identity=28.3950617283951, Blast_Score=147, Evalue=9e-35,
Organism=Homo sapiens, GI4557233, Length=357, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI226958412, Length=327, Percent_Identity=26.9113149847095, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI226958414, Length=327, Percent_Identity=26.9113149847095, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI55749758, Length=598, Percent_Identity=26.0869565217391, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI225735629, Length=591, Percent_Identity=26.5651438240271, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI45827692, Length=591, Percent_Identity=26.5651438240271, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI4557231, Length=324, Percent_Identity=28.3950617283951, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI187960098, Length=324, Percent_Identity=28.3950617283951, Blast_Score=123, Evalue=9e-28,
Organism=Homo sapiens, GI4501857, Length=328, Percent_Identity=27.7439024390244, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI7656849, Length=338, Percent_Identity=23.9644970414201, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI156151445, Length=378, Percent_Identity=25.6613756613757, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI7669494, Length=302, Percent_Identity=22.5165562913907, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI4503943, Length=302, Percent_Identity=22.5165562913907, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI38505218, Length=280, Percent_Identity=24.2857142857143, Blast_Score=74, Evalue=1e-12,
Organism=Escherichia coli, GI1788107, Length=581, Percent_Identity=26.1617900172117, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI145693145, Length=560, Percent_Identity=24.2857142857143, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1786223, Length=351, Percent_Identity=21.0826210826211, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=356, Percent_Identity=21.9101123595506, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=30.8988764044944, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=339, Percent_Identity=30.6784660766962, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=28.3707865168539, Blast_Score=162, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=292, Percent_Identity=30.4794520547945, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17538396, Length=325, Percent_Identity=28, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=32.3275862068966, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=27.1812080536913, Blast_Score=134, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17570075, Length=325, Percent_Identity=27.0769230769231, Blast_Score=133, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=24.9336870026525, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17534899, Length=325, Percent_Identity=26.1538461538462, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193202679, Length=591, Percent_Identity=23.1810490693739, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=328, Percent_Identity=25.9146341463415, Blast_Score=113, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71982178, Length=266, Percent_Identity=28.1954887218045, Blast_Score=109, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=412, Percent_Identity=25, Blast_Score=107, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=335, Percent_Identity=26.2686567164179, Blast_Score=104, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=362, Percent_Identity=23.4806629834254, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=335, Percent_Identity=25.0746268656716, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560308, Length=575, Percent_Identity=23.4782608695652, Blast_Score=96, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559526, Length=569, Percent_Identity=22.4956063268893, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=31.2312312312312, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21356377, Length=366, Percent_Identity=27.8688524590164, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24646207, Length=355, Percent_Identity=29.8591549295775, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24666513, Length=341, Percent_Identity=28.1524926686217, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21355753, Length=326, Percent_Identity=26.0736196319018, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24660351, Length=327, Percent_Identity=28.1345565749235, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI18859661, Length=533, Percent_Identity=25.328330206379, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24654656, Length=469, Percent_Identity=24.7334754797441, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581924, Length=394, Percent_Identity=26.3959390862944, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355181, Length=392, Percent_Identity=26.2755102040816, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648257, Length=525, Percent_Identity=22.8571428571429, Blast_Score=71, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 132824; Mature: 132824

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00061 ADH_SHORT ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRQRQILSLTPHHAATLVDVLRAWTQQKGDAVGFAFWQDDKQVHLTYTELDHKARAIA
CCCCCCHHEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEHHCCHHHHHH
VHLQAMRWQGERVLLMYPPGLELIAALMGCFYAGLVAVPVYPPRPNNNITRLLSIGEDAQ
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCC
AKGILTKVSLENSLKQVSKNTAFEALPKVATDSIILSVGEAWQNPQLTADSLALLQYTSG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCHHHEEEEEECCC
STGTPKGVMLSHGNLLHNLGQIYQRFGHSANTHVVSWLPPYHDMGLIGGILQPLYGGFPV
CCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCH
TLMSPVAFLQKPLRWLQAISQTQATTSGAPNFAYEMCVRNIRLDECLDLDLSSWELAFTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCEEEECC
AEPIRQETLERFATTFKTYGFRREAFYPCYGLAEATLFVTGKNKDEIVFNHTSQSLVSCG
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCHHHHHHCC
SPSDDQTIIIVNPESREPCAAGEEGEIWLKGASVAQGYWQNPQETKATFQGALASGTGGF
CCCCCCEEEEECCCCCCCCCCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHHHCCCCCCC
LRTGDLGYLNSGELFVTGRIKDVMIIRGQNYYPHDIEAAVSQCHPALSAYWGAAFSVEVD
EECCCCCEECCCCEEEEECCEEEEEEECCCCCCCHHHHHHHHHCHHHHHHCCCEEEEEEC
GEERLVVVQEVERSSWRRLDEDGIIAAIRGAVSCEFGLQVYGICLLKPGSIPKTSSGKVQ
CCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHEEECCCEEEEEEEECCCCCCCCCCCCHH
RFACREGFVCGGLDVVFGWELAHAEAQRRREERGEEKEKIVDGLIGWLRDYANHHINSRL
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MDERRCISPHVVLDFGNKGLLGMQVPSCYGGLGLGYTDTIRIIQQLGAIDPTLALFVGLN
HHHHHCCCCEEEEECCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
NVLGVRPILMYGTDALKAELLPILATGRELAAFALTETGAGANPQAIQSQAISDGDGWLL
HHHCCCCCEEECCHHHHHHHHHHHHCCCHHHEEEEECCCCCCCHHHHHHHHCCCCCCEEE
RGEKIWSGSAAWAGVINVFVKHQQGISGFVVRRGSPGLRQGAEALTMGMRGMVQNTVYLE
ECCEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
DIPVTSAQVLGEVGKGMNVAQDAMMYGRLAIASACVGGMQRCVQLMWRYSQRRQIATGKL
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LDHPIVLHRLQELTCAITVVQSLVMRVGKLLDAGETVPAEVYAACKISAPEFYWQAADLL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEECCCHHHHHHHHHH
VQTLGGRGYIESNIAPQILRDARVLRIFEGPTETLCGFLGARVLKQGETLQNFLCQTLGA
HHHHCCCCEECCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VEVGTRLRDAVDKIRGRCFDGANITVQRWVYHQVGKLATEAILWAVLDDKSAINWVKHRF
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DEQLQEILSFNTDNLLFLNGQSLVHHLNEYTKTIGDIEQNLAGEAQELDELLRQSGENPQ
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
FIPTTADLPASSEIQTWLKTWISQKLRQPISTIDVNRAFAEYGMDSVTAIELTQDLQEWL
EECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KISQPLDATIAWNFPTINALANYLGEVTKENAVPSDNNLDDLSTTDIAQLLSQEIAIARH
HHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
RKPQMK
CCCCCC
>Mature Secondary Structure
MINRQRQILSLTPHHAATLVDVLRAWTQQKGDAVGFAFWQDDKQVHLTYTELDHKARAIA
CCCCCCHHEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEHHCCHHHHHH
VHLQAMRWQGERVLLMYPPGLELIAALMGCFYAGLVAVPVYPPRPNNNITRLLSIGEDAQ
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCC
AKGILTKVSLENSLKQVSKNTAFEALPKVATDSIILSVGEAWQNPQLTADSLALLQYTSG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCHHHEEEEEECCC
STGTPKGVMLSHGNLLHNLGQIYQRFGHSANTHVVSWLPPYHDMGLIGGILQPLYGGFPV
CCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCH
TLMSPVAFLQKPLRWLQAISQTQATTSGAPNFAYEMCVRNIRLDECLDLDLSSWELAFTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCEEEECC
AEPIRQETLERFATTFKTYGFRREAFYPCYGLAEATLFVTGKNKDEIVFNHTSQSLVSCG
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCHHHHHHCC
SPSDDQTIIIVNPESREPCAAGEEGEIWLKGASVAQGYWQNPQETKATFQGALASGTGGF
CCCCCCEEEEECCCCCCCCCCCCCCCEEEECCHHHHCCCCCCHHHHHHHHHHHCCCCCCC
LRTGDLGYLNSGELFVTGRIKDVMIIRGQNYYPHDIEAAVSQCHPALSAYWGAAFSVEVD
EECCCCCEECCCCEEEEECCEEEEEEECCCCCCCHHHHHHHHHCHHHHHHCCCEEEEEEC
GEERLVVVQEVERSSWRRLDEDGIIAAIRGAVSCEFGLQVYGICLLKPGSIPKTSSGKVQ
CCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHEEECCCEEEEEEEECCCCCCCCCCCCHH
RFACREGFVCGGLDVVFGWELAHAEAQRRREERGEEKEKIVDGLIGWLRDYANHHINSRL
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MDERRCISPHVVLDFGNKGLLGMQVPSCYGGLGLGYTDTIRIIQQLGAIDPTLALFVGLN
HHHHHCCCCEEEEECCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
NVLGVRPILMYGTDALKAELLPILATGRELAAFALTETGAGANPQAIQSQAISDGDGWLL
HHHCCCCCEEECCHHHHHHHHHHHHCCCHHHEEEEECCCCCCCHHHHHHHHCCCCCCEEE
RGEKIWSGSAAWAGVINVFVKHQQGISGFVVRRGSPGLRQGAEALTMGMRGMVQNTVYLE
ECCEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
DIPVTSAQVLGEVGKGMNVAQDAMMYGRLAIASACVGGMQRCVQLMWRYSQRRQIATGKL
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LDHPIVLHRLQELTCAITVVQSLVMRVGKLLDAGETVPAEVYAACKISAPEFYWQAADLL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEECCCHHHHHHHHHH
VQTLGGRGYIESNIAPQILRDARVLRIFEGPTETLCGFLGARVLKQGETLQNFLCQTLGA
HHHHCCCCEECCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VEVGTRLRDAVDKIRGRCFDGANITVQRWVYHQVGKLATEAILWAVLDDKSAINWVKHRF
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DEQLQEILSFNTDNLLFLNGQSLVHHLNEYTKTIGDIEQNLAGEAQELDELLRQSGENPQ
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
FIPTTADLPASSEIQTWLKTWISQKLRQPISTIDVNRAFAEYGMDSVTAIELTQDLQEWL
EECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KISQPLDATIAWNFPTINALANYLGEVTKENAVPSDNNLDDLSTTDIAQLLSQEIAIARH
HHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
RKPQMK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]