Click here to switch to the map view.

The map label for this gene is yfmR [H]

Identifier: 17228792

GI number: 17228792

Start: 1537345

End: 1539285

Strand: Direct

Name: yfmR [H]

Synonym: alr1297

Alternate gene names: 17228792

Gene position: 1537345-1539285 (Clockwise)

Preceding gene: 17228791

Following gene: 17228793

Centisome position: 23.97

GC content: 41.94

Gene sequence:

>1941_bases
ATGAGCGTCATCACATTACAATCAGTTAAAAAAGACTTTGGAATCAAAGAAATTTTAAAAGATGCGAGCTTTAGTTTAGA
TGCTACAGATAAAGTTGGCTTAATAGGTACAAACGGTTCCGGCAAATCCACTTTATTAAAAATGATCGCCGGCATAGAAT
CTATTGATAGTGGACAAATTCTCTGTACTTCTGGTTCTAAAATCATCTACTTACCCCAACAGCCAGACTTAGATGAAAAT
CGTACTGTTTTAGAACAGATTTTCGCCGACAGTGGCGAACAAATGACATTAGTACGTGAGTATGAAGAACTTTCTGATAA
ACTAGCTCACTACCCAGAAGATAGCCAAATCATGTCCCGCCTTTCTGTTGTCATGCAGCGCATGGACGCAACTAACGCTT
GGGAGTTAGAAACTAATGCCAAAATTATCCTCAGCAGGCTAGGAATCACTGATTTTGATGCGCCCATTGGGAGTTTATCT
GGCGGCTATCGTAAACGTATAGCTTTAGCTACTGCCTTACTTGCAGAACCAGATGTTTTACTGATGGATGAGCCAACAAA
CCATCTGGATGCTCTATCTGTAGAATGGCTACAAAGCTATCTTAACCGCTTTCGTGGTGCATTATTTCTGATTACACATG
ATCGCTATTTTTTAGATAAAGTCACCAACCGCATCATCGAAATCGACCGAGGCGATGTCTATAACTATGCAGGTAATTAC
TCATACTACCTGGAAAAAAAAGCTCTGGCGGAAGAATCAGCCATTAGTACCCAACGCAAACATCAGGGAGTATTGCGACG
AGAACTAGAATGGCTCAAGCGTGGCCCCAAAGCTAGAAGTACTAAGCAAAAAGCCCGCATTCAACGCGTCCAAGCCATGC
GCGAAACTGAGTTTAAACAAACTCAAGGTAAAGTGGATATCTCCACGGTTAGCCGCCGCATTGGCAAAAAAGTGATTGAT
TTGTATAACATTTCTAAAGCCTATGATGACCGCATCTTAATCAAAGATTTTACCTACGAATTTAGCCCGGAAGACCGCAT
CGGCATTATTGGTGGTAACGGTGCTGGCAAGTCTACCTTAATGAATATCATCACCGGGCGTGTAGAACCCGATGCCGGTA
AAGTAGAAATTGGTTCTACCATCCACATTGGTTATTTTGACCAACATTCTGAAGAATTACTCACAGCTTTAGATGAAAAT
CAGCGCGTGATTGACTACATTAAAGAAGAGGGAGAATTTGTTCAGATAGCCGATGGCACAAAAATTACTGCTTCCCAAAT
GTTAGAACGGTTTCTTTTTCCAGGGAATCAGCAGTATGCACCAATTCATAAACTATCCGGTGGTGAAAAACGCCGATTAT
TCCTGCTGCGTATCCTCATCAGCGCCCCCAATGTCTTAATTTTAGATGAACCGACAAACGATTTAGATGTGCAAACACTA
GCAGTCTTAGAAGACTACTTAGAAGATTTTAGCGGTAGCGTCATCGTCGTTTCCCACGATCGCTACTTTTTAGACCGCAC
TGTTGATACAATATTTGCCTTGGAAGCAGGTGGGAGCCTGCGGCAATATCCAGGTAATTACTCAGTTTATCTAGACTACA
AAAAAGCCGAGGAAGCACAACAAGCAACAGTCAACACTAAAGAAAAGACAAAAAATTCCCCAGAAACAAAAGTTACATCG
CAAACTAAAGATGTAGAAACTAAAAAACGCCGTAGACTGTCCAATTGGGAAAAGCGGGAATTTGCCGAGCTAGAAGGCAA
AATTGCTCAATTAGAGGATGAAAAAACCCAAGCCGAGCAGGAACTGACTCATGTCCCTCCTGGCAATTATACTCAAGTAC
AAAAACTCTACGAACAAATAGAAGCGCTGAAGCAAGCAATTGATGTAGCGACTGAGCGCTGGTTAGAATTAGCTGAGATA
GAGTCTTCCGAGAGTGGGTGA

Upstream 100 bases:

>100_bases
AATCTGAGGTACGCTACACTCAATAAACGTACCTCTTCCTCCTAAAATATTTTGAATTTTGCGCCTGTGTGTCAGCTAAA
AAGTATCTTTTAAAATTGCT

Downstream 100 bases:

>100_bases
GCGCAACATGATAGCTCAAAAGCAGAATCTACCATCAAACCTGGCATTAAAGGATGCCCGACTTGCCAACACAAATCAAT
TCTTTAAAAACTCGGCAACT

Product: ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 645

Protein sequence:

>646_residues
MSVITLQSVKKDFGIKEILKDASFSLDATDKVGLIGTNGSGKSTLLKMIAGIESIDSGQILCTSGSKIIYLPQQPDLDEN
RTVLEQIFADSGEQMTLVREYEELSDKLAHYPEDSQIMSRLSVVMQRMDATNAWELETNAKIILSRLGITDFDAPIGSLS
GGYRKRIALATALLAEPDVLLMDEPTNHLDALSVEWLQSYLNRFRGALFLITHDRYFLDKVTNRIIEIDRGDVYNYAGNY
SYYLEKKALAEESAISTQRKHQGVLRRELEWLKRGPKARSTKQKARIQRVQAMRETEFKQTQGKVDISTVSRRIGKKVID
LYNISKAYDDRILIKDFTYEFSPEDRIGIIGGNGAGKSTLMNIITGRVEPDAGKVEIGSTIHIGYFDQHSEELLTALDEN
QRVIDYIKEEGEFVQIADGTKITASQMLERFLFPGNQQYAPIHKLSGGEKRRLFLLRILISAPNVLILDEPTNDLDVQTL
AVLEDYLEDFSGSVIVVSHDRYFLDRTVDTIFALEAGGSLRQYPGNYSVYLDYKKAEEAQQATVNTKEKTKNSPETKVTS
QTKDVETKKRRRLSNWEKREFAELEGKIAQLEDEKTQAEQELTHVPPGNYTQVQKLYEQIEALKQAIDVATERWLELAEI
ESSESG

Sequences:

>Translated_646_residues
MSVITLQSVKKDFGIKEILKDASFSLDATDKVGLIGTNGSGKSTLLKMIAGIESIDSGQILCTSGSKIIYLPQQPDLDEN
RTVLEQIFADSGEQMTLVREYEELSDKLAHYPEDSQIMSRLSVVMQRMDATNAWELETNAKIILSRLGITDFDAPIGSLS
GGYRKRIALATALLAEPDVLLMDEPTNHLDALSVEWLQSYLNRFRGALFLITHDRYFLDKVTNRIIEIDRGDVYNYAGNY
SYYLEKKALAEESAISTQRKHQGVLRRELEWLKRGPKARSTKQKARIQRVQAMRETEFKQTQGKVDISTVSRRIGKKVID
LYNISKAYDDRILIKDFTYEFSPEDRIGIIGGNGAGKSTLMNIITGRVEPDAGKVEIGSTIHIGYFDQHSEELLTALDEN
QRVIDYIKEEGEFVQIADGTKITASQMLERFLFPGNQQYAPIHKLSGGEKRRLFLLRILISAPNVLILDEPTNDLDVQTL
AVLEDYLEDFSGSVIVVSHDRYFLDRTVDTIFALEAGGSLRQYPGNYSVYLDYKKAEEAQQATVNTKEKTKNSPETKVTS
QTKDVETKKRRRLSNWEKREFAELEGKIAQLEDEKTQAEQELTHVPPGNYTQVQKLYEQIEALKQAIDVATERWLELAEI
ESSESG
>Mature_645_residues
SVITLQSVKKDFGIKEILKDASFSLDATDKVGLIGTNGSGKSTLLKMIAGIESIDSGQILCTSGSKIIYLPQQPDLDENR
TVLEQIFADSGEQMTLVREYEELSDKLAHYPEDSQIMSRLSVVMQRMDATNAWELETNAKIILSRLGITDFDAPIGSLSG
GYRKRIALATALLAEPDVLLMDEPTNHLDALSVEWLQSYLNRFRGALFLITHDRYFLDKVTNRIIEIDRGDVYNYAGNYS
YYLEKKALAEESAISTQRKHQGVLRRELEWLKRGPKARSTKQKARIQRVQAMRETEFKQTQGKVDISTVSRRIGKKVIDL
YNISKAYDDRILIKDFTYEFSPEDRIGIIGGNGAGKSTLMNIITGRVEPDAGKVEIGSTIHIGYFDQHSEELLTALDENQ
RVIDYIKEEGEFVQIADGTKITASQMLERFLFPGNQQYAPIHKLSGGEKRRLFLLRILISAPNVLILDEPTNDLDVQTLA
VLEDYLEDFSGSVIVVSHDRYFLDRTVDTIFALEAGGSLRQYPGNYSVYLDYKKAEEAQQATVNTKEKTKNSPETKVTSQ
TKDVETKKRRRLSNWEKREFAELEGKIAQLEDEKTQAEQELTHVPPGNYTQVQKLYEQIEALKQAIDVATERWLELAEIE
SSESG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=528, Percent_Identity=27.2727272727273, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI10947137, Length=562, Percent_Identity=29.5373665480427, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI27881506, Length=562, Percent_Identity=29.5373665480427, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI69354671, Length=545, Percent_Identity=29.9082568807339, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI10947135, Length=545, Percent_Identity=29.9082568807339, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI27477115, Length=199, Percent_Identity=29.6482412060301, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI2367384, Length=527, Percent_Identity=38.7096774193548, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1787182, Length=646, Percent_Identity=32.1981424148607, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1789751, Length=615, Percent_Identity=29.9186991869919, Blast_Score=275, Evalue=8e-75,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=29.0740740740741, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI87081782, Length=531, Percent_Identity=25.8003766478343, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786975, Length=492, Percent_Identity=24.5934959349593, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788165, Length=202, Percent_Identity=30.1980198019802, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786872, Length=253, Percent_Identity=26.8774703557312, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789593, Length=221, Percent_Identity=26.6968325791855, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789891, Length=225, Percent_Identity=26.2222222222222, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI48994883, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789873, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994997, Length=223, Percent_Identity=25.1121076233184, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786398, Length=240, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787547, Length=231, Percent_Identity=25.5411255411255, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=23.7668161434978, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=548, Percent_Identity=27.7372262773723, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17555318, Length=537, Percent_Identity=29.2364990689013, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=28.8679245283019, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17510237, Length=359, Percent_Identity=25.3481894150418, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=542, Percent_Identity=30.0738007380074, Blast_Score=217, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6321121, Length=548, Percent_Identity=28.6496350364964, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=30.6701030927835, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=28.9405684754522, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=28.6458333333333, Blast_Score=123, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6322980, Length=283, Percent_Identity=28.2685512367491, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641342, Length=505, Percent_Identity=30.2970297029703, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24666836, Length=515, Percent_Identity=30.2912621359223, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24642252, Length=550, Percent_Identity=30.1818181818182, Blast_Score=209, Evalue=6e-54,
Organism=Drosophila melanogaster, GI18859989, Length=550, Percent_Identity=30.1818181818182, Blast_Score=209, Evalue=6e-54,
Organism=Drosophila melanogaster, GI116007184, Length=263, Percent_Identity=27.7566539923954, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221500365, Length=263, Percent_Identity=27.7566539923954, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641565, Length=218, Percent_Identity=26.605504587156, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920532, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24580930, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73089; Mature: 72957

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVITLQSVKKDFGIKEILKDASFSLDATDKVGLIGTNGSGKSTLLKMIAGIESIDSGQI
CCEEEHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCE
LCTSGSKIIYLPQQPDLDENRTVLEQIFADSGEQMTLVREYEELSDKLAHYPEDSQIMSR
EEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHH
LSVVMQRMDATNAWELETNAKIILSRLGITDFDAPIGSLSGGYRKRIALATALLAEPDVL
HHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
LMDEPTNHLDALSVEWLQSYLNRFRGALFLITHDRYFLDKVTNRIIEIDRGDVYNYAGNY
EECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEECCCCCEEECCCCE
SYYLEKKALAEESAISTQRKHQGVLRRELEWLKRGPKARSTKQKARIQRVQAMRETEFKQ
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TQGKVDISTVSRRIGKKVIDLYNISKAYDDRILIKDFTYEFSPEDRIGIIGGNGAGKSTL
HCCCEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCCCEEEEECCCCCHHHH
MNIITGRVEPDAGKVEIGSTIHIGYFDQHSEELLTALDENQRVIDYIKEEGEFVQIADGT
HHHHHCCCCCCCCCEEECCEEEEEECCCHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCC
KITASQMLERFLFPGNQQYAPIHKLSGGEKRRLFLLRILISAPNVLILDEPTNDLDVQTL
EEHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
AVLEDYLEDFSGSVIVVSHDRYFLDRTVDTIFALEAGGSLRQYPGNYSVYLDYKKAEEAQ
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEEEECCCCHHCCCCCEEEEEEEHHHHHHH
QATVNTKEKTKNSPETKVTSQTKDVETKKRRRLSNWEKREFAELEGKIAQLEDEKTQAEQ
HHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHCCHHHHHHH
ELTHVPPGNYTQVQKLYEQIEALKQAIDVATERWLELAEIESSESG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVITLQSVKKDFGIKEILKDASFSLDATDKVGLIGTNGSGKSTLLKMIAGIESIDSGQI
CEEEHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCE
LCTSGSKIIYLPQQPDLDENRTVLEQIFADSGEQMTLVREYEELSDKLAHYPEDSQIMSR
EEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHH
LSVVMQRMDATNAWELETNAKIILSRLGITDFDAPIGSLSGGYRKRIALATALLAEPDVL
HHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
LMDEPTNHLDALSVEWLQSYLNRFRGALFLITHDRYFLDKVTNRIIEIDRGDVYNYAGNY
EECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEECCCCCEEECCCCE
SYYLEKKALAEESAISTQRKHQGVLRRELEWLKRGPKARSTKQKARIQRVQAMRETEFKQ
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
TQGKVDISTVSRRIGKKVIDLYNISKAYDDRILIKDFTYEFSPEDRIGIIGGNGAGKSTL
HCCCEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCCCEEEEECCCCCHHHH
MNIITGRVEPDAGKVEIGSTIHIGYFDQHSEELLTALDENQRVIDYIKEEGEFVQIADGT
HHHHHCCCCCCCCCEEECCEEEEEECCCHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCC
KITASQMLERFLFPGNQQYAPIHKLSGGEKRRLFLLRILISAPNVLILDEPTNDLDVQTL
EEHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
AVLEDYLEDFSGSVIVVSHDRYFLDRTVDTIFALEAGGSLRQYPGNYSVYLDYKKAEEAQ
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEEEECCCCHHCCCCCEEEEEEEHHHHHHH
QATVNTKEKTKNSPETKVTSQTKDVETKKRRRLSNWEKREFAELEGKIAQLEDEKTQAEQ
HHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHCCHHHHHHH
ELTHVPPGNYTQVQKLYEQIEALKQAIDVATERWLELAEIESSESG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]