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The map label for this gene is pip [H]

Identifier: 17228765

GI number: 17228765

Start: 1508709

End: 1509659

Strand: Direct

Name: pip [H]

Synonym: alr1270

Alternate gene names: 17228765

Gene position: 1508709-1509659 (Clockwise)

Preceding gene: 17228761

Following gene: 17228766

Centisome position: 23.52

GC content: 41.43

Gene sequence:

>951_bases
ATGCGCGAACTTTACCCACCCATCGAACCTTATAAAGAAGGTAAGTTACAAGTTTCCCAATTACACACCATTCATTTTGA
AGAATCAGGAAACCCCCAAGGTAAACCCATAGTTTTACTGCATGGTGGCCCTGGTGGTGGTTGTCCGCCAGTTTATCGGC
AATATTTTCATCCTGAAAAATGGCGGTTGGTAATGTTTGACCAACGTGGCTGCGGTAAAAGTCAACCCCATGCAGAATTA
AGAGAAAATACAACTTGGGATTTGGTTAATGATATTGAGAAACTACGAGAGCATTTAGGAATAGAAAAGTGGGTGGTTTT
TGGTGGGAGTTGGGGCAGTACTTTATCATTAGCTTATAGTCAAACTCACCCTGAGCGTTGTTTAGGCTTAATTTTACGCG
GGATATTTTTACTCAGACAAAAAGAGTTGCGTTGGTTTTATCAAGAAGGTGCTAGTTATATTTTTCCTGATGCTTGGGAG
GAATATTTGCAACCGATTCCTGTAAATGAAAGAGACGATTTACTCACAGCTTATTACCAACGTTTAACTAGTCCAGATTC
ACAAGTTAGACGAGAAGCGGCTCGTGCTTGGTCAATTTGGGAAGCTAGTACTAGTAGATTATTTCCTGATACCCAGCTAA
AGCAAACTTTTGGAGCAGATAATTTTGCTGATGCTTTTGCGCGAATTGAATGTCATTACTTTATGAATAAAGGATTTTTC
AATTCTGAGGATCAATTACTATTAAATGTTCATCGTATCCGCCAGATTCCATCGGTGATTGTCCAGGGACGTTATGATGT
GGTTTGTCCAATGACATCAGCTTGGGAATTACACCGGGCTTGGCCGGAAGCAGAGTTTATTGTAGTTCCTGATGCTGGTC
ATTCGATGAGTGAAGTGGGGATTCGTAGTGCTTTGATTGAGGCGACGGATAGGTTTGCTGATGGAGGCTAG

Upstream 100 bases:

>100_bases
CTAGTCTGCTGTGGGGAGATGATTATCTAACCAGTTGTGCGATCGCCTATACTCAGCGCTGTCTATTATATGATTACTGA
ACTACTCCTCAAGTATTAAA

Downstream 100 bases:

>100_bases
AGATTATCCTTTTTAACGCGGAGTAACGCTAAGGTTAGCGCAGAGGTACGCTGAGGATTTTTCTTGTATATTCTGAGGTA
TTAAACTGACACAAATGAAA

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRELYPPIEPYKEGKLQVSQLHTIHFEESGNPQGKPIVLLHGGPGGGCPPVYRQYFHPEKWRLVMFDQRGCGKSQPHAEL
RENTTWDLVNDIEKLREHLGIEKWVVFGGSWGSTLSLAYSQTHPERCLGLILRGIFLLRQKELRWFYQEGASYIFPDAWE
EYLQPIPVNERDDLLTAYYQRLTSPDSQVRREAARAWSIWEASTSRLFPDTQLKQTFGADNFADAFARIECHYFMNKGFF
NSEDQLLLNVHRIRQIPSVIVQGRYDVVCPMTSAWELHRAWPEAEFIVVPDAGHSMSEVGIRSALIEATDRFADGG

Sequences:

>Translated_316_residues
MRELYPPIEPYKEGKLQVSQLHTIHFEESGNPQGKPIVLLHGGPGGGCPPVYRQYFHPEKWRLVMFDQRGCGKSQPHAEL
RENTTWDLVNDIEKLREHLGIEKWVVFGGSWGSTLSLAYSQTHPERCLGLILRGIFLLRQKELRWFYQEGASYIFPDAWE
EYLQPIPVNERDDLLTAYYQRLTSPDSQVRREAARAWSIWEASTSRLFPDTQLKQTFGADNFADAFARIECHYFMNKGFF
NSEDQLLLNVHRIRQIPSVIVQGRYDVVCPMTSAWELHRAWPEAEFIVVPDAGHSMSEVGIRSALIEATDRFADGG
>Mature_316_residues
MRELYPPIEPYKEGKLQVSQLHTIHFEESGNPQGKPIVLLHGGPGGGCPPVYRQYFHPEKWRLVMFDQRGCGKSQPHAEL
RENTTWDLVNDIEKLREHLGIEKWVVFGGSWGSTLSLAYSQTHPERCLGLILRGIFLLRQKELRWFYQEGASYIFPDAWE
EYLQPIPVNERDDLLTAYYQRLTSPDSQVRREAARAWSIWEASTSRLFPDTQLKQTFGADNFADAFARIECHYFMNKGFF
NSEDQLLLNVHRIRQIPSVIVQGRYDVVCPMTSAWELHRAWPEAEFIVVPDAGHSMSEVGIRSALIEATDRFADGG

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36414; Mature: 36414

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELYPPIEPYKEGKLQVSQLHTIHFEESGNPQGKPIVLLHGGPGGGCPPVYRQYFHPEK
CCCCCCCCCCCCCCCEEEEHEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCC
WRLVMFDQRGCGKSQPHAELRENTTWDLVNDIEKLREHLGIEKWVVFGGSWGSTLSLAYS
EEEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEC
QTHPERCLGLILRGIFLLRQKELRWFYQEGASYIFPDAWEEYLQPIPVNERDDLLTAYYQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHH
RLTSPDSQVRREAARAWSIWEASTSRLFPDTQLKQTFGADNFADAFARIECHYFMNKGFF
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHEEEECCCCC
NSEDQLLLNVHRIRQIPSVIVQGRYDVVCPMTSAWELHRAWPEAEFIVVPDAGHSMSEVG
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCCEEEECCCCCCHHHHH
IRSALIEATDRFADGG
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRELYPPIEPYKEGKLQVSQLHTIHFEESGNPQGKPIVLLHGGPGGGCPPVYRQYFHPEK
CCCCCCCCCCCCCCCEEEEHEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCC
WRLVMFDQRGCGKSQPHAELRENTTWDLVNDIEKLREHLGIEKWVVFGGSWGSTLSLAYS
EEEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEC
QTHPERCLGLILRGIFLLRQKELRWFYQEGASYIFPDAWEEYLQPIPVNERDDLLTAYYQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHH
RLTSPDSQVRREAARAWSIWEASTSRLFPDTQLKQTFGADNFADAFARIECHYFMNKGFF
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHEEEECCCCC
NSEDQLLLNVHRIRQIPSVIVQGRYDVVCPMTSAWELHRAWPEAEFIVVPDAGHSMSEVG
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCCEEEECCCCCCHHHHH
IRSALIEATDRFADGG
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA