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The map label for this gene is ubiH [H]

Identifier: 16766358

GI number: 16766358

Start: 3218465

End: 3219643

Strand: Reverse

Name: ubiH [H]

Synonym: STM3057

Alternate gene names: 16766358

Gene position: 3219643-3218465 (Counterclockwise)

Preceding gene: 16766359

Following gene: 16766357

Centisome position: 66.28

GC content: 60.98

Gene sequence:

>1179_bases
ATGAGCGTCATTATCGTTGGCGGCGGCATGGCAGGCGCGACGCTGGCGCTGGCCATCTCTCAGTTCAGTCATGGGACGTT
GCCGGTACACCTGATTGAAGCGAAAGCGCCTGAAGCCGACGGTCATCCCGGCTTTGACGCCAGAGCGATTGCGCTGGCGG
CGGGCACTTGTCAGCAACTGGCGCGAATTGGCGTCTGGCAGGCGATTTCCGATTGCGCAACGGCAATCAACACCGTACAC
GTCAGCGATCGCGGCCATGCCGGATTTGTGACTCTCGACGCGCAGGACTACAGTCTGGCAGCGTTGGGGCACGTTGCGGA
GCTGCATGATATCGGGCTGCGTCTGTTTGCGCTCTTGCGTAAAGCGCCAGGCGTTACGCTGCACTGCCCGGAGCGCGTAG
CCAGCGTGTCGCGTACCCAACAGCAGGTTAACGTCACTCTGGAAAACGGCAATGTGATAGCTGGCAGCGTGCTGGTGGCG
GCTAACGGTACCCACTCCGCGCTCGCGTCACGCTGCGGCGTTGACTGGCATCAGGAGCCTTACGAACAGTTAGCGGTGAT
AGCGAATGTCGCAACCGCTATCCCGCACCAGGGACGCGCCTTTGAACGTTTTACCCCCAATGGCCCGCTGGCGATGTTGC
CGATGTCGCATGGCCGATGTTCGCTGGTTTGGTGTCACCCGCTCGACCAGCGCGATGAGGTGCTGAGCTGGTCCGACGCG
CAGTTCTGCCATGCATTGCAGGCCGCGTTCGGCTGGCGGCTGGGGCGAATTACTCAGGCCGGTAAGCGCAGCGCGTATCC
GCTTGCCCTGACTACGGCGGCGAAAGTGTTTTCTCACCGGACTGTCGTGGTCGGCAATGCGGCGCAGACGTTGCATCCTA
TCGCCGGACAAGGGTTTAATCTCGGTCTGCGCGATGTCATGAGCCTGGCGGAAACGCTGGTCGCGGCACAGGACGCGGGC
GAGGATATTGGCGCCTGGCACGTGTTATCGCGCTATCAGCAGCGTCGTCAGGTTGACCGGGATACGACGATTGGCGTAAC
GAACGGTCTGGTCCATCTGTTTGCAAATCGTTGGGCGCCGCTGGTTATTGGGCGCAATATCGGTTTAATGGCGATGGAAT
TATTACCACCTGCGCGCGATGCGCTGGCACAGCGGACCTTAGGTTGGGTTGCGCGTTAA

Upstream 100 bases:

>100_bases
ATGACATTGTCATTACCGAAACCGGTAATGAAAACCTGACCGCTGGCGTTGTGAAGAAGGCGGATGACATTGAGGCATTA
ATGGCGGCGGCGCGGCAGCA

Downstream 100 bases:

>100_bases
GCCGATCTGTAGGCCGGATAAGGCGTTCACGCCGCCATCCGGCATCGTGTTCGTAAAAATACCGGATGGCGGCTTCGCCT
TATCCGGCCTACGGTTTTGA

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPGFDARAIALAAGTCQQLARIGVWQAISDCATAINTVH
VSDRGHAGFVTLDAQDYSLAALGHVAELHDIGLRLFALLRKAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVA
ANGTHSALASRCGVDWHQEPYEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHGRCSLVWCHPLDQRDEVLSWSDA
QFCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKVFSHRTVVVGNAAQTLHPIAGQGFNLGLRDVMSLAETLVAAQDAG
EDIGAWHVLSRYQQRRQVDRDTTIGVTNGLVHLFANRWAPLVIGRNIGLMAMELLPPARDALAQRTLGWVAR

Sequences:

>Translated_392_residues
MSVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPGFDARAIALAAGTCQQLARIGVWQAISDCATAINTVH
VSDRGHAGFVTLDAQDYSLAALGHVAELHDIGLRLFALLRKAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVA
ANGTHSALASRCGVDWHQEPYEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHGRCSLVWCHPLDQRDEVLSWSDA
QFCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKVFSHRTVVVGNAAQTLHPIAGQGFNLGLRDVMSLAETLVAAQDAG
EDIGAWHVLSRYQQRRQVDRDTTIGVTNGLVHLFANRWAPLVIGRNIGLMAMELLPPARDALAQRTLGWVAR
>Mature_391_residues
SVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPGFDARAIALAAGTCQQLARIGVWQAISDCATAINTVHV
SDRGHAGFVTLDAQDYSLAALGHVAELHDIGLRLFALLRKAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVAA
NGTHSALASRCGVDWHQEPYEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHGRCSLVWCHPLDQRDEVLSWSDAQ
FCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKVFSHRTVVVGNAAQTLHPIAGQGFNLGLRDVMSLAETLVAAQDAGE
DIGAWHVLSRYQQRRQVDRDTTIGVTNGLVHLFANRWAPLVIGRNIGLMAMELLPPARDALAQRTLGWVAR

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=387, Percent_Identity=26.6149870801034, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI32967307, Length=376, Percent_Identity=27.3936170212766, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1789274, Length=392, Percent_Identity=79.8469387755102, Blast_Score=651, Evalue=0.0,
Organism=Escherichia coli, GI1789273, Length=393, Percent_Identity=30.2798982188295, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786883, Length=375, Percent_Identity=32.2666666666667, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25146631, Length=426, Percent_Identity=26.5258215962441, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6321694, Length=450, Percent_Identity=24.6666666666667, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19920760, Length=421, Percent_Identity=24.4655581947743, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 41840; Mature: 41709

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPGFDARAIALAAGTCQQL
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHH
ARIGVWQAISDCATAINTVHVSDRGHAGFVTLDAQDYSLAALGHVAELHDIGLRLFALLR
HHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVAANGTHSALASRCGVDWHQEP
HCCCCEEECHHHHHHHHHCCEEEEEEEECCCEEEEEEEEEECCCHHHHHHHCCCCCCCCH
YEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHGRCSLVWCHPLDQRDEVLSWSDA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHCCCCCH
QFCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKVFSHRTVVVGNAAQTLHPIAGQGFN
HHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCC
LGLRDVMSLAETLVAAQDAGEDIGAWHVLSRYQQRRQVDRDTTIGVTNGLVHLFANRWAP
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCE
LVIGRNIGLMAMELLPPARDALAQRTLGWVAR
EEEECCCCEEHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPGFDARAIALAAGTCQQL
EEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHH
ARIGVWQAISDCATAINTVHVSDRGHAGFVTLDAQDYSLAALGHVAELHDIGLRLFALLR
HHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVAANGTHSALASRCGVDWHQEP
HCCCCEEECHHHHHHHHHCCEEEEEEEECCCEEEEEEEEEECCCHHHHHHHCCCCCCCCH
YEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHGRCSLVWCHPLDQRDEVLSWSDA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHCCCCCH
QFCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKVFSHRTVVVGNAAQTLHPIAGQGFN
HHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCC
LGLRDVMSLAETLVAAQDAGEDIGAWHVLSRYQQRRQVDRDTTIGVTNGLVHLFANRWAP
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCE
LVIGRNIGLMAMELLPPARDALAQRTLGWVAR
EEEECCCCEEHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]