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The map label for this gene is pipB2 [H]

Identifier: 16766091

GI number: 16766091

Start: 2926802

End: 2927854

Strand: Reverse

Name: pipB2 [H]

Synonym: STM2780

Alternate gene names: 16766091

Gene position: 2927854-2926802 (Counterclockwise)

Preceding gene: 16766094

Following gene: 228960703

Centisome position: 60.28

GC content: 44.44

Gene sequence:

>1053_bases
ATGGAGCGTTCACTCGATAGTCTGGCTGGTATGGCTAAATCTGCTTTTGGCGCGGGGACTTCTGCTGCTATGCGGCAAGC
TACCTCGCCCAAAACCATTCTGGAATATATCATTAACTTTTTTACCTGTGGTGGGATACGTCGGAGAAATGAAACACAAT
ATCAGGAATTGATAGAGACTATGGCTGAGACATTGAAAAGTACAATGCCTGACAGAGGTGCTCCGTTGCCAGAAAACATC
ATCCTGGATGATATGGATGGGTGTCGTGTCGAATTTAATCTTCCTGGTGAGAATAACGAAGCTGGACAAGTTATTGTACG
AGTCAGTAAAGGCGACCATTCTGAGACAAGAGAAATTCCGCTTGCCTCTTTTGAAAAAATATGCCGAGCTTTACTATTCA
GATGCGAATTTTCTCTCCCTCAGGATTCTGTAATATTAACTGCCCAGGGAGGCATGAATCTTAAAGGCGCTGTCCTTACC
GGAGCAAATCTGACGTCAGAAAATTTATGTGACGCAGACTTAAGCGGCGCAAATTTAGAGGGGGCAGTGCTGTTTATGGC
GGATTGTGAAGGTGCAAATTTTAAGGGCGCAAATCTATCGGGAACATCACTAGGCGACAGTAATTTCAAGAACGCCTGTC
TGGAAGATAGCATTATGTGTGGCGCTACCCTCGATCACGCTAATCTTACTGGCGCCAATTTACAACACGCGAGTCTGTTA
GGCTGTAGCATGATAGAATGTAATTGCTCCGGTGCAAATATGGATCACACTAATCTTTCAGGCGCAACCCTTATACGTGC
TGATATGAGCGGTGCGACATTACAGGGTGCTACTATAATGGCTGCAATTATGGAAGGCGCTGTCTTAACCCGGGCAAACC
TGCGAAAGGCGAGTTTCATTTCTACGAACCTGGACGGGGCTGATTTGGCTGAGGCTAATTTAAACAATACCTGTTTTAAA
GATTGTACACTAACCGATTTGCGTACTGAAGACGCCACAATGTCTACAAGCACACAAACACTCTTTAACGAATTTTATAG
TGAAAATATTTAG

Upstream 100 bases:

>100_bases
ATGTAACCAGACGTAAAGGGGGTATTCACCTTATCTCTAAATGCAAATCTATATGATAAATTTTATCATGCACTGTGTTG
CTGTCTCTGGGAGAAAATAT

Downstream 100 bases:

>100_bases
CCCTTTTTGACGTAAATCTGAAATAAAAGCAATGTAAGAATAACAATCTGCTACTGAATAGTAGCTGAGAGTAAATTATT
TACAGTATCTTTTATTATTA

Product: secreted effector protein

Products: NA

Alternate protein names: Type III effector pipB2 [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MERSLDSLAGMAKSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIETMAETLKSTMPDRGAPLPENI
ILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
GANLTSENLCDADLSGANLEGAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLL
GCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASFISTNLDGADLAEANLNNTCFK
DCTLTDLRTEDATMSTSTQTLFNEFYSENI

Sequences:

>Translated_350_residues
MERSLDSLAGMAKSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIETMAETLKSTMPDRGAPLPENI
ILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
GANLTSENLCDADLSGANLEGAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLL
GCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASFISTNLDGADLAEANLNNTCFK
DCTLTDLRTEDATMSTSTQTLFNEFYSENI
>Mature_350_residues
MERSLDSLAGMAKSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIETMAETLKSTMPDRGAPLPENI
ILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
GANLTSENLCDADLSGANLEGAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLL
GCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASFISTNLDGADLAEANLNNTCFK
DCTLTDLRTEDATMSTSTQTLFNEFYSENI

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the

COG id: COG1357

COG function: function code S; Uncharacterized low-complexity proteins

Gene ontology:

Cell location: Secreted. Host membrane (By similarity). Note=Secreted via the type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 pentapeptide repeat domains [H]

Homologues:

Organism=Homo sapiens, GI39753959, Length=159, Percent_Identity=35.2201257861635, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221377802, Length=157, Percent_Identity=36.3057324840764, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646 [H]

Pfam domain/function: PF00805 Pentapeptide [H]

EC number: NA

Molecular weight: Translated: 37274; Mature: 37274

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSLDSLAGMAKSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIET
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
MAETLKSTMPDRGAPLPENIILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIP
HHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHCCC
LASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTSENLCDADLSGANLE
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
GAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLL
EEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEECCEECCCCCCCCCCCHHHHH
GCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASFI
CCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEECHHHHHHHHHHCHHHHHHCCCHHHEE
STNLDGADLAEANLNNTCFKDCTLTDLRTEDATMSTSTQTLFNEFYSENI
ECCCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MERSLDSLAGMAKSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIET
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
MAETLKSTMPDRGAPLPENIILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIP
HHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHCCC
LASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTSENLCDADLSGANLE
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
GAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLL
EEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEECCEECCCCCCCCCCCHHHHH
GCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASFI
CCEEEEECCCCCCCCCCCCCCEEEEEECCCCCEECHHHHHHHHHHCHHHHHHCCCHHHEE
STNLDGADLAEANLNNTCFKDCTLTDLRTEDATMSTSTQTLFNEFYSENI
ECCCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA