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The map label for this gene is ptsG [H]

Identifier: 16766070

GI number: 16766070

Start: 2895879

End: 2897420

Strand: Reverse

Name: ptsG [H]

Synonym: STM2758

Alternate gene names: 16766070

Gene position: 2897420-2895879 (Counterclockwise)

Preceding gene: 16766074

Following gene: 16766069

Centisome position: 59.65

GC content: 57.52

Gene sequence:

>1542_bases
ATGAAAAGATTCAACCTTCTGCAAATGTTACAAAGCATCGGGCGATCGTTAATGATCCCCATTGCCATGCTGCCTGCCGC
CGGTATTTTGCTGGCTTTTGGTGTTAGCTTTCAGGATCCCAATATTGTCGCCAGCCTGCCGTTTCTCGGCACTGACGGGC
TGGTTCACGTGCTGAAGCTGATGGCGGAAGCGGGCAGTGCGATTTTCGCCAACCTGCCGCTGCTGTTTGCGGTCGGCGTG
GCGGTGGGACTTAGTGACGATCAGGGCATTGCCGGGCTGTCGGCGATCGCCGGGTTTTTGATTATGAACGTCACCATCGG
CCAGTTTCTGGGGATCACGCCCGAATCGGTGGCGCAGGTGCGTGACTACACGATGGTGCTGGGCATCCCTTCGCTGCAGA
CCGGCGTGTTTGGCGGCATCATTATCGGGATTATCGCCGCCTGGCTGTATAAACGCTATTACCGCATCCAGCTTCCTTCA
TGGCTGGAGTTCTTCTCCGGCAAGCGATTTGTGCCGATAGTGACCTCCTTCGCCGCGCTGTTTGTCGGGCTGGTGATGGC
GGTGGTCTGGCCGCCGGTTCAGCATCTGATTAATGGCCTGTCGAATACCATGACGGTGCAGGGGCCGGGCGTGTCCGCCT
TCCTGTTCGGTTTTGTCGAGCGGCTGCTGATCCCGTTTGGTCTTAACCATGTCTGGTGGCCGACGTTCTGGCTGCAGTTT
GGCGAGTACGTGAACAAAGCCGGGCAGGTGGTGCATGGCGACCAGCTTATCTTCTTTGCCCAGTTGAAAGATCAGGTGCC
GATTACCGCCGGAACCTTTATGGCCGGGCTGACGCCGATCAAGATGTTCTGTATTCCGGCGATTGCGCTGGCGATCTACC
GCTGCGCCAGCCCGGAAAACATAGCGCGTGTGAAGGGCATTATGCTCTCTGGCGCGATCACTTCCATCGTCTGCGGTATC
ACCGAGCCGATTGAGTTCTCCTTCCTGTTTGTTGCACCCGTGCTGTATGGCATTCACGCCGTCCTGGCGGGGCTGGTGTT
CCTGCTGATGGAGTGGTTCAGCGTGCACATCGGGCTCTCTTTCTCCGGCGGGCTTATCGACTATCTCTTCTTTGGCGTTC
TGCCGCGAGCGCCTCACTGGTACATGGTATTCCCGGTCGGGCTGGTGATGGGCGCGGTGTACTACGTCCTGTTTACCTTT
GCCATCCGTCGCTGGAATTTGCTGACGCCGGGCCGTGAAGTCGAAGAAACCGCTGTGGCGCAGGAAAGCGAACAGAACGA
CCTGGTGAGCGGCATCATTCTGGCCTATGGCGGATTGGGGAATATGACCAGCATCGAAGCCTGCATGTCACGTCTGCGCA
TTGACGTGACGGATAAGACGCTGGTGGACAAAGCGCTGCTGAAACAGCTTGGCGCGGCGGGCGTCGTTGAGGTCGGGAAC
AACATTCAGAGCGTCTTTGGCATGAAATCCGACCGGCTGAAAGAGGCGATCCGCGCGATTAAAGCGCATCCGGTTTCCGG
ACATTGTGAACCCATACACTAA

Upstream 100 bases:

>100_bases
CTGTTTTTTTAATCATTTCGGGTTCGGATACTGAAGGTGTTCGGAGCAGAACCTGCTGTTGTGCGAATCCCTGTCATAAA
GACGCGCTCAGGAGATCGAG

Downstream 100 bases:

>100_bases
ATAATTCGAGTTGTAGCAAGGCGGCAAGCGCGTGAGTTCCCGGGAGCATAGATAACTATGTGACCGGGATGAAGGCGCGC
AGCCAACGTAGCAGCAACTT

Product: phosphotransferase system IIC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKRFNLLQMLQSIGRSLMIPIAMLPAAGILLAFGVSFQDPNIVASLPFLGTDGLVHVLKLMAEAGSAIFANLPLLFAVGV
AVGLSDDQGIAGLSAIAGFLIMNVTIGQFLGITPESVAQVRDYTMVLGIPSLQTGVFGGIIIGIIAAWLYKRYYRIQLPS
WLEFFSGKRFVPIVTSFAALFVGLVMAVVWPPVQHLINGLSNTMTVQGPGVSAFLFGFVERLLIPFGLNHVWWPTFWLQF
GEYVNKAGQVVHGDQLIFFAQLKDQVPITAGTFMAGLTPIKMFCIPAIALAIYRCASPENIARVKGIMLSGAITSIVCGI
TEPIEFSFLFVAPVLYGIHAVLAGLVFLLMEWFSVHIGLSFSGGLIDYLFFGVLPRAPHWYMVFPVGLVMGAVYYVLFTF
AIRRWNLLTPGREVEETAVAQESEQNDLVSGIILAYGGLGNMTSIEACMSRLRIDVTDKTLVDKALLKQLGAAGVVEVGN
NIQSVFGMKSDRLKEAIRAIKAHPVSGHCEPIH

Sequences:

>Translated_513_residues
MKRFNLLQMLQSIGRSLMIPIAMLPAAGILLAFGVSFQDPNIVASLPFLGTDGLVHVLKLMAEAGSAIFANLPLLFAVGV
AVGLSDDQGIAGLSAIAGFLIMNVTIGQFLGITPESVAQVRDYTMVLGIPSLQTGVFGGIIIGIIAAWLYKRYYRIQLPS
WLEFFSGKRFVPIVTSFAALFVGLVMAVVWPPVQHLINGLSNTMTVQGPGVSAFLFGFVERLLIPFGLNHVWWPTFWLQF
GEYVNKAGQVVHGDQLIFFAQLKDQVPITAGTFMAGLTPIKMFCIPAIALAIYRCASPENIARVKGIMLSGAITSIVCGI
TEPIEFSFLFVAPVLYGIHAVLAGLVFLLMEWFSVHIGLSFSGGLIDYLFFGVLPRAPHWYMVFPVGLVMGAVYYVLFTF
AIRRWNLLTPGREVEETAVAQESEQNDLVSGIILAYGGLGNMTSIEACMSRLRIDVTDKTLVDKALLKQLGAAGVVEVGN
NIQSVFGMKSDRLKEAIRAIKAHPVSGHCEPIH
>Mature_513_residues
MKRFNLLQMLQSIGRSLMIPIAMLPAAGILLAFGVSFQDPNIVASLPFLGTDGLVHVLKLMAEAGSAIFANLPLLFAVGV
AVGLSDDQGIAGLSAIAGFLIMNVTIGQFLGITPESVAQVRDYTMVLGIPSLQTGVFGGIIIGIIAAWLYKRYYRIQLPS
WLEFFSGKRFVPIVTSFAALFVGLVMAVVWPPVQHLINGLSNTMTVQGPGVSAFLFGFVERLLIPFGLNHVWWPTFWLQF
GEYVNKAGQVVHGDQLIFFAQLKDQVPITAGTFMAGLTPIKMFCIPAIALAIYRCASPENIARVKGIMLSGAITSIVCGI
TEPIEFSFLFVAPVLYGIHAVLAGLVFLLMEWFSVHIGLSFSGGLIDYLFFGVLPRAPHWYMVFPVGLVMGAVYYVLFTF
AIRRWNLLTPGREVEETAVAQESEQNDLVSGIILAYGGLGNMTSIEACMSRLRIDVTDKTLVDKALLKQLGAAGVVEVGN
NIQSVFGMKSDRLKEAIRAIKAHPVSGHCEPIH

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=509, Percent_Identity=43.4184675834971, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1787908, Length=521, Percent_Identity=38.3877159309021, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1786894, Length=508, Percent_Identity=37.992125984252, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 55689; Mature: 55689

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFNLLQMLQSIGRSLMIPIAMLPAAGILLAFGVSFQDPNIVASLPFLGTDGLVHVLKL
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHH
MAEAGSAIFANLPLLFAVGVAVGLSDDQGIAGLSAIAGFLIMNVTIGQFLGITPESVAQV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RDYTMVLGIPSLQTGVFGGIIIGIIAAWLYKRYYRIQLPSWLEFFSGKRFVPIVTSFAAL
HHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
FVGLVMAVVWPPVQHLINGLSNTMTVQGPGVSAFLFGFVERLLIPFGLNHVWWPTFWLQF
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GEYVNKAGQVVHGDQLIFFAQLKDQVPITAGTFMAGLTPIKMFCIPAIALAIYRCASPEN
HHHHHHCCCEEECCCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHH
IARVKGIMLSGAITSIVCGITEPIEFSFLFVAPVLYGIHAVLAGLVFLLMEWFSVHIGLS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSGGLIDYLFFGVLPRAPHWYMVFPVGLVMGAVYYVLFTFAIRRWNLLTPGREVEETAVA
CCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QESEQNDLVSGIILAYGGLGNMTSIEACMSRLRIDVTDKTLVDKALLKQLGAAGVVEVGN
HCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCHHHHCC
NIQSVFGMKSDRLKEAIRAIKAHPVSGHCEPIH
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]