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The map label for this gene is entD [H]

Identifier: 16763961

GI number: 16763961

Start: 640808

End: 641512

Strand: Reverse

Name: entD [H]

Synonym: STM0584

Alternate gene names: 16763961

Gene position: 641512-640808 (Counterclockwise)

Preceding gene: 16763962

Following gene: 16763960

Centisome position: 13.21

GC content: 55.89

Gene sequence:

>705_bases
ATGCTGACATCTCATTTTCCCCTTCCCTTTGCCGGACACAGGCTGCATATCGTCGACTTTGATGCGAGCAGCTTTCGCGA
ACACGACCTGCTATGGCTACCTCATCACGATCGGCTCCGGTCTGCCGGACGCAAGCGTAAAGCTGAACATCTGGCAGGCC
GCATTGCCGCCGTTCATGCGCTACGCGAGGTGGGCGTCAGGACAGTGCCCGGTATGGGCGACAAGCGACAGCCGCTATGG
CCGGACGGCCTATTTGGCAGCATCAGCCACTGTGCGACAACGGCGCTGGCCGTCATATCCCGACAGCGTATCGGCATTGA
TATAGAAAAAATCATGAGTCAGCACACGGCGACAGAGCTGGCGCCGTCCATTATTGATAGCGATGAGCGCCAAATTCTCC
AGGCGAGCTTGCTCCCTTTTCCGCTTGCCCTGACGCTGGCTTTCTCCGCCAAAGAGAGCGTTTATAAAGCCTTTTCAGAC
CGCGTCACGCTCCCGGGATTCAATAGCGCAAAAGTTACCTCGCTTACCGCCACGCACATCTCGTTACATCTGCTGCCAGC
CTTTGCCGCCACGATGGCTGAACGTACCGTCCGTACAGAATGGTTTCAACGTGACAATAGCGTTATTACTCTTGTTTCTG
CAATAACGCGCGTTCCCCACGACAGGAGCGCTCCCGCTTCTATACTTAGCGCAATACCCCGATAA

Upstream 100 bases:

>100_bases
CACCTATAACGAACCAGGACGTACGTGGTATATGAGCATTAATACCCATTTCTGATGGCAACCTTCCCTCCCTCATTCGG
GGAGGGAATTGGCAAAAACG

Downstream 100 bases:

>100_bases
ATGAGATCCCTATGGCGCTGAATGATTTTCACGTTTCTGAACCTTATACGCTTGGTATTGAGCTGGAGATGCAGGTGATC
AATCCACCTGGCTACGATTT

Product: phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGMGDKRQPLW
PDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSD
RVTLPGFNSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRDNSVITLVSAITRVPHDRSAPASILSAIPR

Sequences:

>Translated_234_residues
MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGMGDKRQPLW
PDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSD
RVTLPGFNSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRDNSVITLVSAITRVPHDRSAPASILSAIPR
>Mature_234_residues
MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGMGDKRQPLW
PDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATELAPSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSD
RVTLPGFNSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRDNSVITLVSAITRVPHDRSAPASILSAIPR

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin [H]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family [H]

Homologues:

Organism=Escherichia coli, GI1786797, Length=183, Percent_Identity=57.9234972677596, Blast_Score=207, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR003542 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: 2.7.8.-

Molecular weight: Translated: 25826; Mature: 25826

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA
CCCCCCCCCCCCCEEEEEECCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHH
SLHLLPAFAATMAERTVRTEWFQRDNSVITLVSAITRVPHDRSAPASILSAIPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA
CCCCCCCCCCCCCEEEEEECCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHH
SLHLLPAFAATMAERTVRTEWFQRDNSVITLVSAITRVPHDRSAPASILSAIPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]