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The map label for this gene is manX [H]

Identifier: 16763953

GI number: 16763953

Start: 635931

End: 636401

Strand: Reverse

Name: manX [H]

Synonym: STM0576

Alternate gene names: 16763953

Gene position: 636401-635931 (Counterclockwise)

Preceding gene: 16763954

Following gene: 16763952

Centisome position: 13.1

GC content: 55.63

Gene sequence:

>471_bases
ATGATCAAATTAGTGCGCATTGATTACCGCCTGCTGCACGGCCAGGTGGTCTTCGCCTGGACCCGGGCGCTGGATATCGA
CCATATCATCGTCGCTAACGCCAACGCCGCCGGCGACGCGTTTGTCTCTATGTCATTAAGTCTGGCAAAACCCGCTGGCG
TGTCGCTGGACATTATCACGGTGGAACAGGCGGCGGAAAAACTCGCCAGCGGCAAGCTGGATCACAAAAAAGTGATGGTG
GTGCTGGGAAATACCGCCGAAACCCTCGCCTTCGTCGAGAAAGTGCCAGGGATTAGCGTTATCAACTACGGCGGTATCGC
GCAAAAAGAGGGCGCGCAGCAGTTCGGCAAAGCCATATACCTGACCGAGCAGGAGATTGCCGATAGCCAGGCGCTAAAAG
CCAAAGGCATCCGTCTGGAAATGCGCCAGGTTCCGGCTCATTCCGCCGAATTGCTTAACGATAAACTCTGA

Upstream 100 bases:

>100_bases
GACGCGGCCATTACCTACGCCACCAATGCGGCGCGTGAATCCATTGTCTTTATCAACACGCTAATAACACAACCATCCGC
TGACCTACAGGGAGAATCCC

Downstream 100 bases:

>100_bases
ACCCGGAGGTCACTATGTTGCTCACCGCAACGCTGCTCGGCCTGATTGCCGCACTGGGCATTCTTGACGGGCGTTTACTC
GGCGTGTCGATGATTGACCG

Product: PTS system mannose-specific enzyme IIAB

Products: NA

Alternate protein names: EIIAB-Man; Mannose-specific phosphotransferase enzyme IIA component; EIII-Man; PTS system mannose-specific EIIA component; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MIKLVRIDYRLLHGQVVFAWTRALDIDHIIVANANAAGDAFVSMSLSLAKPAGVSLDIITVEQAAEKLASGKLDHKKVMV
VLGNTAETLAFVEKVPGISVINYGGIAQKEGAQQFGKAIYLTEQEIADSQALKAKGIRLEMRQVPAHSAELLNDKL

Sequences:

>Translated_156_residues
MIKLVRIDYRLLHGQVVFAWTRALDIDHIIVANANAAGDAFVSMSLSLAKPAGVSLDIITVEQAAEKLASGKLDHKKVMV
VLGNTAETLAFVEKVPGISVINYGGIAQKEGAQQFGKAIYLTEQEIADSQALKAKGIRLEMRQVPAHSAELLNDKL
>Mature_156_residues
MIKLVRIDYRLLHGQVVFAWTRALDIDHIIVANANAAGDAFVSMSLSLAKPAGVSLDIITVEQAAEKLASGKLDHKKVMV
VLGNTAETLAFVEKVPGISVINYGGIAQKEGAQQFGKAIYLTEQEIADSQALKAKGIRLEMRQVPAHSAELLNDKL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788120, Length=144, Percent_Identity=32.6388888888889, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI87082217, Length=148, Percent_Identity=27.027027027027, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004701
- InterPro:   IPR013789
- InterPro:   IPR004720
- InterPro:   IPR018455 [H]

Pfam domain/function: PF03610 EIIA-man; PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16821; Mature: 16821

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS51101 PTS_EIIB_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVRIDYRLLHGQVVFAWTRALDIDHIIVANANAAGDAFVSMSLSLAKPAGVSLDIIT
CEEEEEEEEEEECCEEEEEEEECCCCCEEEEECCCCCCCEEEEEEEEECCCCCCEEEEEE
VEQAAEKLASGKLDHKKVMVVLGNTAETLAFVEKVPGISVINYGGIAQKEGAQQFGKAIY
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCEEE
LTEQEIADSQALKAKGIRLEMRQVPAHSAELLNDKL
EEHHHHCCCHHHHHCCCEEEEECCCCHHHHHHCCCC
>Mature Secondary Structure
MIKLVRIDYRLLHGQVVFAWTRALDIDHIIVANANAAGDAFVSMSLSLAKPAGVSLDIIT
CEEEEEEEEEEECCEEEEEEEECCCCCEEEEECCCCCCCEEEEEEEEECCCCCCEEEEEE
VEQAAEKLASGKLDHKKVMVVLGNTAETLAFVEKVPGISVINYGGIAQKEGAQQFGKAIY
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCEEE
LTEQEIADSQALKAKGIRLEMRQVPAHSAELLNDKL
EEHHHHCCCHHHHHCCCEEEEECCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]