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The map label for this gene is glmS [H]

Identifier: 16763950

GI number: 16763950

Start: 633240

End: 634283

Strand: Reverse

Name: glmS [H]

Synonym: STM0573

Alternate gene names: 16763950

Gene position: 634283-633240 (Counterclockwise)

Preceding gene: 16763951

Following gene: 16763949

Centisome position: 13.06

GC content: 58.14

Gene sequence:

>1044_bases
ATGAACGAGACGCCCCTTCGCCTGCTGGAGATGCTGACGCAGACGCGGGAAGATCTCTGGCGCGCGGCGCAGGCGCTAAC
GGAACGCGGCGTCACCCGCATTATTCTGACAGGCTCCGGCACGTCATACCACGGCGCGCTGACCGCTCGCACGTTTATGC
AGCGCTGGTGCGCATTACCAGTGGATGTCTGCTGGCCGTTTATGCTTGACGACGAGACGCTTGCCCGCAGCGGCAAGGCG
CTGGTTGTCGGCATCTCCCAGGGCGGCGGCAGCCTCTCAACGCTGGCGGCGATGGAGCGCGCCCGCAATGTTGGTCATAT
CACCGCCTCAATGGCTGGCGTGGCGCCTGCGACTATCGACCGGGCGGCGGATTATATCCTTACCGTTCCCTGCGGCGAAG
AAACCGCTGGCGCGAAAACAAAAGGCTATCACTGCACGGTTCTCAATTTGATGCTGCTGGCGCTCGCCGTCGCCGGGCAG
CAACAGCGGCTGGACGGCGAACAGCGCCGGTCACTGCTGCTGCGGATGGAAAAGACCTTTAACCACCTGCCCGCGCTGGT
TACCGCCTCGCAGGCGTGGGCGCAAACCAATGCGCTGGCGCTGCGCGATAGCGCAGATATTCGTCTGACCGGCCCGGCAA
CGCTGTTCGGTACGGTGCAGGAGGGTGCGCTCAAGATGCTGGAGACGTTGCGCTGTCCGGTGTCGGGCTACGAATTCGAG
GAGTTTATTCACGGTATTTACAATGCCTTTAATGCGCAATCCGCACTCATTATGCTCGACCCGCAGCCTGACGCGCGTCA
GGATCGGCTGGCGCAAATACTCGGTGAGTGGACGCCGTCTATTTACCGCATCGGCCCGCAGGTAGAAAATAATGGTCTGA
ATCTGAATTTCCCGTTTGTCAATGATGAGGACTTTGCCGTCTTTGAATATATCATTCCGCTACAAATGCTATGTGCGATA
TTACCCCCGCAAAAAGGCATTAATCCGGCGATACCCAAAGATCCGCAATTCCATCAAAAAATGAAAAGTAAGCAAGAAAT
TTAA

Upstream 100 bases:

>100_bases
ACATTAACTGGATCCTGTTAGGCACCGTCGTGTTTGGGCTTCTTGCCAGCGCGCTGGGCCTGCTTTGACGAGAGGTAACA
CTATGCAAGTAGAAGACTAT

Downstream 100 bases:

>100_bases
TTTTTATTAATGCTCGTTATTATCCGCGCTGTTGCGGAGGACGCGCTACACGCTAAGGAGATAAATATGTCTGTTGCTCA
TGAAAATGCCCGCCGTATTA

Product: inner membrane protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNETPLRLLEMLTQTREDLWRAAQALTERGVTRIILTGSGTSYHGALTARTFMQRWCALPVDVCWPFMLDDETLARSGKA
LVVGISQGGGSLSTLAAMERARNVGHITASMAGVAPATIDRAADYILTVPCGEETAGAKTKGYHCTVLNLMLLALAVAGQ
QQRLDGEQRRSLLLRMEKTFNHLPALVTASQAWAQTNALALRDSADIRLTGPATLFGTVQEGALKMLETLRCPVSGYEFE
EFIHGIYNAFNAQSALIMLDPQPDARQDRLAQILGEWTPSIYRIGPQVENNGLNLNFPFVNDEDFAVFEYIIPLQMLCAI
LPPQKGINPAIPKDPQFHQKMKSKQEI

Sequences:

>Translated_347_residues
MNETPLRLLEMLTQTREDLWRAAQALTERGVTRIILTGSGTSYHGALTARTFMQRWCALPVDVCWPFMLDDETLARSGKA
LVVGISQGGGSLSTLAAMERARNVGHITASMAGVAPATIDRAADYILTVPCGEETAGAKTKGYHCTVLNLMLLALAVAGQ
QQRLDGEQRRSLLLRMEKTFNHLPALVTASQAWAQTNALALRDSADIRLTGPATLFGTVQEGALKMLETLRCPVSGYEFE
EFIHGIYNAFNAQSALIMLDPQPDARQDRLAQILGEWTPSIYRIGPQVENNGLNLNFPFVNDEDFAVFEYIIPLQMLCAI
LPPQKGINPAIPKDPQFHQKMKSKQEI
>Mature_347_residues
MNETPLRLLEMLTQTREDLWRAAQALTERGVTRIILTGSGTSYHGALTARTFMQRWCALPVDVCWPFMLDDETLARSGKA
LVVGISQGGGSLSTLAAMERARNVGHITASMAGVAPATIDRAADYILTVPCGEETAGAKTKGYHCTVLNLMLLALAVAGQ
QQRLDGEQRRSLLLRMEKTFNHLPALVTASQAWAQTNALALRDSADIRLTGPATLFGTVQEGALKMLETLRCPVSGYEFE
EFIHGIYNAFNAQSALIMLDPQPDARQDRLAQILGEWTPSIYRIGPQVENNGLNLNFPFVNDEDFAVFEYIIPLQMLCAI
LPPQKGINPAIPKDPQFHQKMKSKQEI

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=313, Percent_Identity=24.9201277955272, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI205277386, Length=309, Percent_Identity=22.9773462783171, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=227, Percent_Identity=27.7533039647577, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532899, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532897, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 38198; Mature: 38198

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETPLRLLEMLTQTREDLWRAAQALTERGVTRIILTGSGTSYHGALTARTFMQRWCALP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
VDVCWPFMLDDETLARSGKALVVGISQGGGSLSTLAAMERARNVGHITASMAGVAPATID
HHHHCCEEECCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHH
RAADYILTVPCGEETAGAKTKGYHCTVLNLMLLALAVAGQQQRLDGEQRRSLLLRMEKTF
HCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHH
NHLPALVTASQAWAQTNALALRDSADIRLTGPATLFGTVQEGALKMLETLRCPVSGYEFE
HHHHHHHHHHHHHHHCCCEEEECCCCEEEECCHHEEHHHHHHHHHHHHHHCCCCCCCCHH
EFIHGIYNAFNAQSALIMLDPQPDARQDRLAQILGEWTPSIYRIGPQVENNGLNLNFPFV
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCC
NDEDFAVFEYIIPLQMLCAILPPQKGINPAIPKDPQFHQKMKSKQEI
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNETPLRLLEMLTQTREDLWRAAQALTERGVTRIILTGSGTSYHGALTARTFMQRWCALP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
VDVCWPFMLDDETLARSGKALVVGISQGGGSLSTLAAMERARNVGHITASMAGVAPATID
HHHHCCEEECCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHH
RAADYILTVPCGEETAGAKTKGYHCTVLNLMLLALAVAGQQQRLDGEQRRSLLLRMEKTF
HCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHH
NHLPALVTASQAWAQTNALALRDSADIRLTGPATLFGTVQEGALKMLETLRCPVSGYEFE
HHHHHHHHHHHHHHHCCCEEEECCCCEEEECCHHEEHHHHHHHHHHHHHHCCCCCCCCHH
EFIHGIYNAFNAQSALIMLDPQPDARQDRLAQILGEWTPSIYRIGPQVENNGLNLNFPFV
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCC
NDEDFAVFEYIIPLQMLCAILPPQKGINPAIPKDPQFHQKMKSKQEI
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA