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The map label for this gene is allB [H]

Identifier: 16763903

GI number: 16763903

Start: 583958

End: 585319

Strand: Direct

Name: allB [H]

Synonym: STM0523

Alternate gene names: 16763903

Gene position: 583958-585319 (Clockwise)

Preceding gene: 16763902

Following gene: 16763904

Centisome position: 12.02

GC content: 51.69

Gene sequence:

>1362_bases
ATGTCTTTTGATTTAATTATTAAGAACGGTACTGTCATCTTAGAAAACGAAGCGAGAGTTATCGATATCGCCGTCCAGGG
CGGAAAAATCGCCGCGATTGGCGAGAACCTGGGGGAAGCGAAAAATGTGCTGGATGCGACGGGATTGATCGTTTCGCCGG
GCATGGTTGACGCGCATACCCACATTTCTGAACCGGGCCGTACCCACTGGGAAGGCTATGAAACCGGTACGCGCGCGGCG
GCGAAAGGCGGTATTACCACGATGATTGAGATGCCGCTCAATCAGCTGCCGGCGACGGTCGATCGTGAGACGATTGAACT
CAAGTTTGACGCGGCAAAAGGTAAATTGACCATCGACGCCGCGCAGTTGGGCGGTTTGGTCTCTTATAACCTGGATCGGC
TGCATGAGCTGGACGAAGTGGGCGTTGTCGGCTTCAAGTGCTTTGTCGCCACCTGCGGCGATCGTGGCATCGATAATGAT
TTTCGCGACGTTAATGACTGGCAGTTTTACAAAGGCGCGCAAAAACTGGGAGAGATGGACCAGACGGTACTGGTACATTG
CGAAAATGCTCTGATTTGCGATGAGCTGGGCGAAGAAGCTAAACGCGAAGGTCGCGTAACGGCGCATGATTATGTCGCCT
CACGTCCGGTATTTACTGAAGTGGAAGCCATTCGTCGCGTGCTGTATCTGGCGAAAGCGGCAGGTTGCCGTCTGCACGTT
TGTCATATCAGCAGCCCGGAGGGGGTAGAGGAAGTAACGCGTGCGCGTCAGGAAGGCCAGGATGTCACCTGTGAATCGTG
CCCGCACTATTTTGTCCTCGATACCGATCAGTTCGAAGAGATTGGCACCCTGGCAAAATGTTCTCCGCCAATTCGCGACC
AGGAAAACCAGAAAGGGATGTGGGAAAAACTGTTTAACGGCGAAATCGACTGCCTGGTATCCGACCACTCTCCATGCCCT
CCGGAAATGAAAGCAGGCAATATCATGCAAGCATGGGGCGGAATTGCCGGACTGCAAAACTGCATGGACGTCATGTTTGA
TGAAGCGGTGCAAAAACGCGGTATGTCGTTGCCGATGTTTGGCAAATTAATGGCGACCAACGCCGCCGATATTTTTGGTC
TGAAACATAAAGGACGTATTGCCCCCGGCAAAGATGCTGACCTGGTCTTTATTCAGCCTGACAGCAGCTATGTTCTGAAA
AATGAAGATCTGGAATATCGCCATAAAGTCAGTCCGTATGTTGGCCGTACTATTGGCGCGCGTATTACCAAAACGATTTT
GCGCGGCGATGTTATTTATGACATCGAGCATGGCTTCCCTGTGCCGCCAAAAGGTCAGTTTATCCTTAAACATCAGCAGT
AA

Upstream 100 bases:

>100_bases
AGAGAAAAAACTCGCAGGTTAAATATTGAAAAAGCATTAAGCGTATTTAATGAAGTGTGCGCTATTTAAAAACTATCTGT
ATCCATACAAGGAGTTTGTT

Downstream 100 bases:

>100_bases
TCCGGTGTGATTTAATGCCCGTCGTCACGACGGGCATTCTCTATTTTAAGGTGTGGATATGTTCCCTGTTATTAACCGCG
AAAGTGTGTTGTCCGGCTTT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVLDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHV
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLK
NEDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ

Sequences:

>Translated_453_residues
MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVLDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHV
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLK
NEDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ
>Mature_452_residues
SFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVLDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAAA
KGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDF
RDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHVC
HISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCPP
EMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLKN
EDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=452, Percent_Identity=26.9911504424779, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI4503379, Length=418, Percent_Identity=28.4688995215311, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4503051, Length=413, Percent_Identity=29.5399515738499, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI62422571, Length=415, Percent_Identity=29.1566265060241, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4503377, Length=430, Percent_Identity=28.6046511627907, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19923821, Length=460, Percent_Identity=26.5217391304348, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI190194363, Length=466, Percent_Identity=26.8240343347639, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI18105007, Length=443, Percent_Identity=25.2821670428894, Blast_Score=112, Evalue=8e-25,
Organism=Escherichia coli, GI1786722, Length=453, Percent_Identity=93.3774834437086, Blast_Score=891, Evalue=0.0,
Organism=Escherichia coli, GI87082175, Length=443, Percent_Identity=29.7968397291196, Blast_Score=169, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71989490, Length=471, Percent_Identity=26.3269639065817, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17539558, Length=469, Percent_Identity=26.226012793177, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193204318, Length=381, Percent_Identity=23.8845144356955, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI86575075, Length=454, Percent_Identity=23.7885462555066, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322218, Length=468, Percent_Identity=34.4017094017094, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI18859883, Length=431, Percent_Identity=33.8747099767981, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI221377917, Length=475, Percent_Identity=25.4736842105263, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24642586, Length=388, Percent_Identity=24.7422680412371, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17137462, Length=470, Percent_Identity=25.1063829787234, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644287, Length=318, Percent_Identity=26.1006289308176, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644289, Length=264, Percent_Identity=26.1363636363636, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49887; Mature: 49756

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVLDATGLIVSPGMVDAHT
CCEEEEEECCEEEEECCCEEEEEEECCCEEEECCCCHHHHHHHHHHCCEEECCCCCCCCC
HISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDA
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFYKGAQKLGEMD
HHHCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCC
QTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHV
CEEEEEECCCEEHHHHHHHHHHCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEE
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGM
EECCCCCCHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHHCCCCCCCCCCCCHH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLKNEDLEYRHKVSPYVGRTIGA
HHHHHCCCHHHEEECCCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHCCCHHHHHHHH
RITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ
HHHHHHHCCCEEEEECCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
SFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVLDATGLIVSPGMVDAHT
CEEEEEECCEEEEECCCEEEEEEECCCEEEECCCCHHHHHHHHHHCCEEECCCCCCCCC
HISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDA
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFYKGAQKLGEMD
HHHCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCC
QTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHV
CEEEEEECCCEEHHHHHHHHHHCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEE
CHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGM
EECCCCCCHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHHCCCCCCCCCCCCHH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLKNEDLEYRHKVSPYVGRTIGA
HHHHHCCCHHHEEECCCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHCCCHHHHHHHH
RITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ
HHHHHHHCCCEEEEECCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA