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The map label for this gene is clpX [H]

Identifier: 16763830

GI number: 16763830

Start: 504085

End: 505356

Strand: Direct

Name: clpX [H]

Synonym: STM0449

Alternate gene names: 16763830

Gene position: 504085-505356 (Clockwise)

Preceding gene: 16763829

Following gene: 16763831

Centisome position: 10.38

GC content: 52.83

Gene sequence:

>1272_bases
ATGACAGATAAACGCAAAGATGGCTCGGGCAAATTGTTGTACTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGCGTCGATTTATGTAACGACATTATTCGCGAAGAAATTAAAG
AAGTTGCTCCGCACCGTGAACGTAGTGCGCTGCCGACGCCGCATGAAATTCGTACCCACCTGGACGATTACGTTATCGGC
CAGGAGCAGGCGAAAAAAGTGCTGGCGGTGGCGGTCTATAACCACTACAAGCGTCTGCGTAACGGCGATACCAGCAATGG
CGTCGAGTTAGGTAAAAGCAACATTCTGCTGATTGGACCGACCGGTTCCGGTAAAACGCTGCTGGCGGAAACGCTGGCGC
GCTTGCTGGATGTGCCGTTCACTATGGCGGATGCGACCACGCTAACCGAAGCGGGTTACGTTGGTGAAGACGTCGAGAAT
ATCATTCAGAAACTGTTGCAGAAATGCGACTACGACGTGCAAAAAGCGCAGCGTGGGATTGTCTACATTGATGAAATCGA
TAAGATTTCGCGTAAATCAGACAATCCGTCCATTACCCGCGATGTTTCCGGCGAAGGCGTACAGCAGGCGTTGCTGAAAC
TGATCGAAGGCACCGTCGCCGCGGTTCCACCGCAGGGCGGTCGCAAACATCCGCAGCAGGAGTTCTTACAGGTAGATACC
TCTAAGATTCTGTTTATCTGCGGCGGCGCGTTTGCCGGTCTGGATAAAGTGATCGCTAACCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCGAAGTCCGACAAAGCCAGCGAAGGCGAGCTGTTGTCGCAGGTTGAACCGGAAG
ATTTGATCAAATTTGGTCTGATTCCTGAGTTTATCGGTCGTCTGCCAGTGGTAGCGACGCTGAATGAACTCAGCGAAGAA
GCGCTGATTCAAATCCTGAAAGAGCCGAAAAATGCGCTGACCAAGCAGTATCAGGCGCTGTTTAACCTGGAAGGCGTCGA
TCTGGAATTCCGTGACGAAGCGCTGGACGCTATCGCCAGGAAAGCAATGGCGCGTAAAACCGGCGCCCGTGGCCTGCGTT
CTATCGTCGAAGCGGCGCTGCTGGATACCATGTACGATTTGCCATCTATGGAAGACGTCGAAAAAGTGGTGATCGACGAG
TCCGTTATTGCCGGTCAGAGTAAGCCGTTGCTGATTTACGGCAAACCGGAAGCGCAGGCTTCTGGCGAATAA

Upstream 100 bases:

>100_bases
ACTAATGAAGGGCGGCACAACGCTGATTAGCGGCTTGCGCCTGAGAATGGCATTTGCGTCGTCGTGTGCGGCACAAAGAA
CAAAGAAGAGGTTTTGACTC

Downstream 100 bases:

>100_bases
TTAAACATTCATACAATCAGTTAGCCAAAAAAGGGGGGATTTTATCTCCCCTTTCGTTTTTCCTGTAAACACGCCGTTGA
ATGTGTGGGAAACATCCCCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIAGQSKPLLIYGKPEAQASGE

Sequences:

>Translated_423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIAGQSKPLLIYGKPEAQASGE
>Mature_422_residues
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQ
EQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENI
IQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTS
KILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEA
LIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDES
VIAGQSKPLLIYGKPEAQASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=342, Percent_Identity=50.8771929824561, Blast_Score=308, Evalue=5e-84,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=98.3490566037736, Blast_Score=843, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=45, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=46.9453376205788, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=46.9453376205788, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=417, Percent_Identity=38.6091127098321, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=40.234375, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=39.906103286385, Blast_Score=276, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=48.125, Blast_Score=292, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=48.125, Blast_Score=292, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46176; Mature: 46045

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
RSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGP
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHCC
IPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC
>Mature Secondary Structure 
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
CCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
RSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGP
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHCC
IPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA