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The map label for this gene is wecF

Identifier: 218930860

GI number: 218930860

Start: 4329911

End: 4330996

Strand: Reverse

Name: wecF

Synonym: YPO3857

Alternate gene names: 218930860

Gene position: 4330996-4329911 (Counterclockwise)

Preceding gene: 218930861

Following gene: 218930859

Centisome position: 93.07

GC content: 50.18

Gene sequence:

>1086_bases
ATGATAACCCTGACTCATGTACTGGGATCTGATATCCCGCACCATAATCTGACCGTGTTGCGTTTCTTTAATGACGTGCT
GGCGAAATGCCTGCCTGTAGAACAGGTACGGCACTTTATGGTCGCGGCAAAAGAAACGGCCCCCTTTTCGTCATTCCCGC
AGTTGGATATCAACACGTACAGTGATAAAAAAGCGTTGGCTGAGGCGGTTATTGCCCGTGCACAGGCGGATCGCAGTGCG
CGTTTCTTTTGGCACGGTCAGTTTAATGTCACTCTCTGGTTGGCGTTGCTAAGCGGTAAAATTAAGCCAGGGCAGGTGTA
TTGGCATGTCTGGGGTGCGGATTTATACGAAGATGCCAAAAGCTTAAAATTTCGTCTGTTTTACCTGCTGCGCCGCATAG
CACAAGGGCGGGTTGGGCACGTGTTTGCCACTCGGGGTGATTTAATTCATTACCAGCAGCGGCATCCTCGCGTGCCCGCC
TCATTACTCTACTTCCCGACCCGTATGGATCCGGCCCTGACCGCTATCAATATTGATAAACCCTTAGCTGGGCCGATGAC
AATCTTGGTGGGGAACTCCGGTGATACCACTAACCGCCATATAGAGGCGCTGAAGGCGATTCATCAGCAATTTGGCCCTG
ACGTCCGGGTGATTATTCCGATGGGCTATCCGGCGAATAACGAAGCGTATATTGAACAGGTTAGGCAGGCGGGGCTCGCA
CTGTTCTCGCAAGACAATCTACGTATCTTAACCGAACAGATCCCCTTTGATGATTATCTGAATATTCTGCGTGAATGTGA
TTTGGGCTATTTCATTTTTAACCGTCAACAAGGTATTGGTACCCTGTGTTTATTGACCCAGTTTGGCGTGCCCTTTGTGC
TAAGCCGTAAAAATCCGTTCTGGCAAGATTTGGCTGAGCAGCATATTCCCGTGTTCTTCTACGGTGACACTCTGGACGAG
CCGATGATCCGTGAGGCACAACGTCAACTGGCAGGGTTAGATAAACAAGCGATCGCTTTCTTCAATCCAAATTATATTGA
GGGCTGGAAGCAAGCGTTGGCTCTGGCTGCGGGGGAACACCCATGA

Upstream 100 bases:

>100_bases
TATATGGCAACGTATATCGTCTATTTTGCGCTCTGTAGCTGCGCATTCCTTGTGTATCGTAGACACTCAGCACCGTAAAC
ACTCTTTACAGTAGAAAAAA

Downstream 100 bases:

>100_bases
CGCTGGGGCAATTTGGCGGTCTATTTTGTATTTATTTGATAGCAGTCATTTTTATTCTGACACTAACCTATCAGGAATTT
CGGCGGGTTAAGTTTAACTT

Product: 4-alpha-L-fucosyltransferase

Products: NA

Alternate protein names: TDP-Fuc4NAc:lipid II Fuc4NAc transferase; Fuc4NAc transferase

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSA
RFFWHGQFNVTLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPA
SLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
LFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDE
PMIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP

Sequences:

>Translated_361_residues
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSA
RFFWHGQFNVTLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPA
SLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
LFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDE
PMIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP
>Mature_361_residues
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSA
RFFWHGQFNVTLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPA
SLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
LFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDE
PMIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 56 family

Homologues:

Organism=Escherichia coli, GI48994971, Length=359, Percent_Identity=63.7883008356546, Blast_Score=487, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WECF_YERPA (Q1CBP2)

Other databases:

- EMBL:   CP000308
- RefSeq:   YP_650075.1
- ProteinModelPortal:   Q1CBP2
- STRING:   Q1CBP2
- GeneID:   4122181
- GenomeReviews:   CP000308_GR
- KEGG:   ypa:YPA_0161
- eggNOG:   NOG04337
- HOGENOM:   HBG296660
- OMA:   IVPMGYP
- ProtClustDB:   PRK02797
- BioCyc:   YPES360102:YPA_0161-MONOMER
- HAMAP:   MF_01002
- InterPro:   IPR009993

Pfam domain/function: PF07429 Fuc4NAc_transf

EC number: NA

Molecular weight: Translated: 41072; Mature: 41072

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTY
CEEEEEHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SDKKALAEAVIARAQADRSARFFWHGQFNVTLWLALLSGKIKPGQVYWHVWGADLYEDAK
CHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHEEHHHCCCCCCEEEEEEECCHHHHHHH
SLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPASLLYFPTRMDPALTAINIDK
HHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHCCCCCHHHEEECCCCCCCEEEEECCC
PLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHE
LFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPF
EECCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCEEEECCCCH
WQDLAEQHIPVFFYGDTLDEPMIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEH
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCC
P
C
>Mature Secondary Structure
MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTY
CEEEEEHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SDKKALAEAVIARAQADRSARFFWHGQFNVTLWLALLSGKIKPGQVYWHVWGADLYEDAK
CHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHEEHHHCCCCCCEEEEEEECCHHHHHHH
SLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPASLLYFPTRMDPALTAINIDK
HHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHCCCCCHHHEEECCCCCCCEEEEECCC
PLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHE
LFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPF
EECCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCEEEECCCCH
WQDLAEQHIPVFFYGDTLDEPMIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEH
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA