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The map label for this gene is coaA [H]

Identifier: 218930763

GI number: 218930763

Start: 4214683

End: 4215633

Strand: Direct

Name: coaA [H]

Synonym: YPO3758

Alternate gene names: 218930763

Gene position: 4214683-4215633 (Clockwise)

Preceding gene: 218930762

Following gene: 218930770

Centisome position: 90.57

GC content: 39.85

Gene sequence:

>951_bases
ATGACAAAAAGAGAACAATCTTTAGCGACGCCTTATCTACAGTTCGATCGTACCCAATGGGCGGCATTACGCGACTCAGT
GCCATTGACACTGACAGAAGAAGAAATCGTTAAACTCAAAGGGATTAACGAAGACCTTTCATTAGATGAAGTGGCACAAA
TTTACCTTCCACTTTCACGCCTACTTAATTTTTATATTAGCTCTAATTTGCGTCGTCAGGCTGTTCTTGAGCAATTCCTT
GGGACTGATGGCCAACGTATTCCTTATGTCATCGGCATTGCTGGCAGCGTAGCTGTCGGTAAAAGTACTACCGCCCGTTT
ATTGCAAGCTTTGCTTAGCCGTTGGCCGGAACATCGTAGCGTAGAACTCATTACAACCGATGGTTTCCTTCATCCTAATA
AGGTGCTCAACGAACGTGGGCTAATGAAGAAAAAAGGATTCCCGGAATCCTATGATATGCATAATCTAGTGAAATTTGTC
TCTGAGGTTAAATCAGGAGCGGATTATGTTACTGCACCCGTTTATTCTCATTTAATATATGATGTTGTCCCTGACGGTAA
TAAGGTAATCAAGCAACCCGACATCCTAATATTAGAAGGCTTAAATGTGCTACAGAGTGGGATGGACTACCCACATGATC
CCCATCACGTATTTGTATCAGACTTTGTAGATTTCTCTATATATGTGGATGCACCTGAGGATTTACTTCAGAGTTGGTAT
ATTAATAGATTTCTTAAATTTCGTCAGGGTGCATTCTCAAATCCAGACTCTTACTTTCATAATTATGCAAAACTACCAGA
GACAGAGGCTATTAAGATCGCCACTCAATTATGGAATGAGATCAATGGATTGAATTTAAAGCAAAATATTTTACCAACTC
GTGAAAGAGCAAGTTTAATAATGACGAAAAGTGCCAATCATGCAGTAGAAAGTGTACGCTTAAGAAAATAA

Upstream 100 bases:

>100_bases
ACACCAAAAACCAAGCTGCCTATAATATGCAGCTTGTTTCTTATCTGGAGTTGGCGTCCAGCGCCTTTCCCAACCTGCGT
TAACAGGCAGAATTTGGCTT

Downstream 100 bases:

>100_bases
TCTATACGGGAGATAGTTATCTCCCATTAATTAATCAGACACCTCGAAGGGATATCTCACCGCCAATATAAGGCTTTATA
TTGCCATCTTGTTCTAATAA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTKREQSLATPYLQFDRTQWAALRDSVPLTLTEEEIVKLKGINEDLSLDEVAQIYLPLSRLLNFYISSNLRRQAVLEQFL
GTDGQRIPYVIGIAGSVAVGKSTTARLLQALLSRWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPESYDMHNLVKFV
SEVKSGADYVTAPVYSHLIYDVVPDGNKVIKQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQSWY
INRFLKFRQGAFSNPDSYFHNYAKLPETEAIKIATQLWNEINGLNLKQNILPTRERASLIMTKSANHAVESVRLRK

Sequences:

>Translated_316_residues
MTKREQSLATPYLQFDRTQWAALRDSVPLTLTEEEIVKLKGINEDLSLDEVAQIYLPLSRLLNFYISSNLRRQAVLEQFL
GTDGQRIPYVIGIAGSVAVGKSTTARLLQALLSRWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPESYDMHNLVKFV
SEVKSGADYVTAPVYSHLIYDVVPDGNKVIKQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQSWY
INRFLKFRQGAFSNPDSYFHNYAKLPETEAIKIATQLWNEINGLNLKQNILPTRERASLIMTKSANHAVESVRLRK
>Mature_315_residues
TKREQSLATPYLQFDRTQWAALRDSVPLTLTEEEIVKLKGINEDLSLDEVAQIYLPLSRLLNFYISSNLRRQAVLEQFLG
TDGQRIPYVIGIAGSVAVGKSTTARLLQALLSRWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPESYDMHNLVKFVS
EVKSGADYVTAPVYSHLIYDVVPDGNKVIKQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQSWYI
NRFLKFRQGAFSNPDSYFHNYAKLPETEAIKIATQLWNEINGLNLKQNILPTRERASLIMTKSANHAVESVRLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=316, Percent_Identity=85.7594936708861, Blast_Score=572, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 36017; Mature: 35885

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKREQSLATPYLQFDRTQWAALRDSVPLTLTEEEIVKLKGINEDLSLDEVAQIYLPLSR
CCCCHHHHCCCHHHHCCHHHHHHHCCCCEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LLNFYISSNLRRQAVLEQFLGTDGQRIPYVIGIAGSVAVGKSTTARLLQALLSRWPEHRS
HHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
VELITTDGFLHPNKVLNERGLMKKKGFPESYDMHNLVKFVSEVKSGADYVTAPVYSHLIY
EEEEEECCCCCCHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHH
DVVPDGNKVIKQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQSWY
HHCCCCCCEECCCCEEEECCHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHH
INRFLKFRQGAFSNPDSYFHNYAKLPETEAIKIATQLWNEINGLNLKQNILPTRERASLI
HHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHEE
MTKSANHAVESVRLRK
EECCCHHHHHHHHCCC
>Mature Secondary Structure 
TKREQSLATPYLQFDRTQWAALRDSVPLTLTEEEIVKLKGINEDLSLDEVAQIYLPLSR
CCCHHHHCCCHHHHCCHHHHHHHCCCCEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LLNFYISSNLRRQAVLEQFLGTDGQRIPYVIGIAGSVAVGKSTTARLLQALLSRWPEHRS
HHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
VELITTDGFLHPNKVLNERGLMKKKGFPESYDMHNLVKFVSEVKSGADYVTAPVYSHLIY
EEEEEECCCCCCHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHH
DVVPDGNKVIKQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQSWY
HHCCCCCCEECCCCEEEECCHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHH
INRFLKFRQGAFSNPDSYFHNYAKLPETEAIKIATQLWNEINGLNLKQNILPTRERASLI
HHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHEE
MTKSANHAVESVRLRK
EECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA