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The map label for this gene is treC [H]

Identifier: 218930703

GI number: 218930703

Start: 4129459

End: 4131126

Strand: Reverse

Name: treC [H]

Synonym: YPO3696

Alternate gene names: 218930703

Gene position: 4131126-4129459 (Counterclockwise)

Preceding gene: 218930704

Following gene: 218930702

Centisome position: 88.77

GC content: 50.24

Gene sequence:

>1668_bases
ATGAATAATCCAATCCCTTGGTGGCAACATGGTGTCATCTATCAGATTTACCCGAAGAGCTTTCAGGACAGTACCGGTAA
TGGCTATGGTGACCTGGCAGGCGTTGCGCAGCGGCTGGATTATCTGCAAAAGCTGGGCGTTGATGCCATTTGGCTGACAC
CGGTGTATGTCTCGCCACAAGTGGATAACGGTTATGACGTGGCGGATTACTGCGCCATTGACCCCGCTTATGGCACATTG
GATGACTTTAAACGTTTGGTCGCGGGTGCTCATCAGCGAGGCATACGCATCATCATGGATATGGTGTTCAATCACACCTC
CACAGAACATGCCTGGTTTAAAGCTTCGCAGGATCGTAATAGCCCTTATCGGCAATTTTATATTTGGCGTGACGGTGACG
GTGGAGACGGCAGTTTACCGAATAACTGGCGCTCGAAATTCGGTGGTCACGCATGGCAGTGGCACGCGGCCAGCGGCCAG
TATTATCTGCATTTGTTTGCCCCAGAGCAGGCTGATCTGAATTGGGAACACCAACCGGTACGCGATGAGCTCAAAAAGGT
GTGTGAATTTTGGGCCGATCTGGGGGTTGATGGTCTGCGTTTGGATGTCATCAATCTGGTGTCCAAACAGCAGGATTTCC
CTAATGATCTGGACGGCGATGGCCGCCGTTTTTATACCGATGGCCCACGCATTCATGAGTTTTTGCAGGAACTGAGCCGC
GATGTGTTCCAGCCACGCCGCCTGATGACGGTAGGCGAGATGTCATCCACCCGTCTCGAGCATTGTCAGCGATATGCGGC
ATTAGGCGGTGATGAGTTATCCATGACCTTTAATTTCCATCACCTGAAAGTGGATTATCTTAACGGTGAAAAGTGGTCAT
TGATGCCGCCGAATCGGGTGGAGTTGAAACACATTTTTAATCAGTGGCAGCAAGGGATGCACAACCGAGCATGGAACGCA
CTATTTTGGTGTAATCACGATCAACCACGCATTGTCTCGCGTTTTGGTCATGAAGGCGCACTACGTTTGCCAGCGGCAAA
GATGCTGGCGATGGTACTGCACGGTATGCAGGGCACGCCTTATATTTATCAGGGGGAAGAAATTGGCATGACGAACCCCA
ATTTCACTGATATCACTCAATACCGTGATGTTGAAAGCCTGAATATGTTTGCCGAACTGAGTGTGGCAGGCCGCGAACCC
GATGAGTTATTGGCGATTCTGGCAGCTAAATCCCGTGATAATAGCCGTACCCCCATGCAATGGGATAGCAGCGATAATGC
GGGTTTCAGCCAAGGCACTCCCTGGATTGCCCCTTGCAGCAATTATCATGAGATTAACGTTAATGCCGCATTGGCCGACG
CTGACTCGGTGTTTTATGCCTATCAATACCTGATAGCCCTGCGTAAACAATACGATATTTTCACTTTCGGTGATTATCAG
GATCTTTGCCCACAGCACCCTGATTTATGGTGCTATTTGCGCAGTTGGCAAGGGAAGCAACTGTTGGTAGTCGCTAACCT
GAGTGAAGAGCCCCAGCGATGGCAACCCGAGGGCCTCACGCTGGACGGTAATTGGCAATTATTGATGAGCAGCTACGACC
AAAGCGCCTTCCAACCGCAAGATATGATATTACGCGGATATGAGGGGATTTATTGGGTATGTGAGTAA

Upstream 100 bases:

>100_bases
GTCTGAAGGGTGTCGATCTGGATGATGTCGATATAAGTTGTGTTCTCCCGCCAGCGGTGATCGTCTGGCGGGGTCATTTT
TCAATGAATAAGAGTCCGCT

Downstream 100 bases:

>100_bases
TTTATTGGGCGCATGGATCATTGAATCGGTGTGTAGGTCATTTCATTGAGTAAGCGCGTTATTTTTCGAAGGGCCGGTGA
TAGGTGACTCCATCAGTGCA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTL
DDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRNSPYRQFYIWRDGDGGDGSLPNNWRSKFGGHAWQWHAASGQ
YYLHLFAPEQADLNWEHQPVRDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSR
DVFQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVELKHIFNQWQQGMHNRAWNA
LFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREP
DELLAILAAKSRDNSRTPMQWDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQ
DLCPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDMILRGYEGIYWVCE

Sequences:

>Translated_555_residues
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTL
DDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRNSPYRQFYIWRDGDGGDGSLPNNWRSKFGGHAWQWHAASGQ
YYLHLFAPEQADLNWEHQPVRDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSR
DVFQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVELKHIFNQWQQGMHNRAWNA
LFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREP
DELLAILAAKSRDNSRTPMQWDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQ
DLCPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDMILRGYEGIYWVCE
>Mature_555_residues
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTL
DDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRNSPYRQFYIWRDGDGGDGSLPNNWRSKFGGHAWQWHAASGQ
YYLHLFAPEQADLNWEHQPVRDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSR
DVFQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVELKHIFNQWQQGMHNRAWNA
LFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREP
DELLAILAAKSRDNSRTPMQWDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQ
DLCPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDMILRGYEGIYWVCE

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=486, Percent_Identity=30.2469135802469, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI61744479, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744481, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744483, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI65506891, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744475, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744477, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790687, Length=547, Percent_Identity=73.8574040219378, Blast_Score=833, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=360, Percent_Identity=26.3888888888889, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=38.4615384615385, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565753, Length=378, Percent_Identity=25.1322751322751, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=481, Percent_Identity=25.3638253638254, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322245, Length=538, Percent_Identity=36.9888475836431, Blast_Score=342, Evalue=6e-95,
Organism=Saccharomyces cerevisiae, GI6321726, Length=582, Percent_Identity=34.7079037800687, Blast_Score=334, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6322241, Length=584, Percent_Identity=35.445205479452, Blast_Score=327, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6322021, Length=584, Percent_Identity=35.445205479452, Blast_Score=327, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6324416, Length=584, Percent_Identity=35.445205479452, Blast_Score=327, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6321731, Length=586, Percent_Identity=34.1296928327645, Blast_Score=309, Evalue=9e-85,
Organism=Saccharomyces cerevisiae, GI6319776, Length=586, Percent_Identity=33.9590443686007, Blast_Score=307, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24583747, Length=542, Percent_Identity=34.6863468634686, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24583749, Length=542, Percent_Identity=34.6863468634686, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI221330053, Length=497, Percent_Identity=36.2173038229376, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24583745, Length=545, Percent_Identity=33.394495412844, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI45549022, Length=528, Percent_Identity=33.3333333333333, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24586599, Length=529, Percent_Identity=32.5141776937618, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24586597, Length=496, Percent_Identity=34.2741935483871, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24586593, Length=497, Percent_Identity=32.5955734406439, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24586589, Length=533, Percent_Identity=33.9587242026266, Blast_Score=248, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24586591, Length=495, Percent_Identity=32.3232323232323, Blast_Score=245, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24586587, Length=512, Percent_Identity=30.46875, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI281360393, Length=440, Percent_Identity=30, Blast_Score=182, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 64077; Mature: 64077

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVADYCAIDPAYGTLDDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRN
CCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCC
SPYRQFYIWRDGDGGDGSLPNNWRSKFGGHAWQWHAASGQYYLHLFAPEQADLNWEHQPV
CCCEEEEEEECCCCCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCH
RDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHH
DVFQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRV
HHHCCHHEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEECCCEEECCCCCHH
ELKHIFNQWQQGMHNRAWNALFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTP
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCC
YIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDELLAILAAKSRDNSRTPMQ
EEEECCEECCCCCCCCCHHHHCCHHHHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCCE
WDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQ
ECCCCCCCCCCCCCCEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCHH
DLCPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQ
HHCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCH
DMILRGYEGIYWVCE
HHHHCCCCCEEEEEC
>Mature Secondary Structure
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVADYCAIDPAYGTLDDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRN
CCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCC
SPYRQFYIWRDGDGGDGSLPNNWRSKFGGHAWQWHAASGQYYLHLFAPEQADLNWEHQPV
CCCEEEEEEECCCCCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCH
RDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHH
DVFQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRV
HHHCCHHEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEECCCEEECCCCCHH
ELKHIFNQWQQGMHNRAWNALFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTP
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCC
YIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDELLAILAAKSRDNSRTPMQ
EEEECCEECCCCCCCCCHHHHCCHHHHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCCE
WDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQ
ECCCCCCCCCCCCCCEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCHH
DLCPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQ
HHCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCH
DMILRGYEGIYWVCE
HHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]