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The map label for this gene is tldD [H]

Identifier: 218930683

GI number: 218930683

Start: 4096985

End: 4098430

Strand: Direct

Name: tldD [H]

Synonym: YPO3672

Alternate gene names: 218930683

Gene position: 4096985-4098430 (Clockwise)

Preceding gene: 218930682

Following gene: 218930693

Centisome position: 88.04

GC content: 53.6

Gene sequence:

>1446_bases
ATGAGCCTCTCATTTGTCAGTGAGCAGTTACTCACTGCTAACAAGTTGAACCATCAGGACTTGTTCTCAGTGTTGGGGCA
GCTAACTGAACGCCGCCTCGATTATGCTGACCTGTATTTCCAGTCCAGCTATCACGAGGCCTGGGTGTTGGAAGACAGCA
TCATCAAAGACGGCTCCTACAATATTGATCAGGGTGTGGGCGTACGTGCGGTAAGTGGTGAAAAAACCGGTTTTGCCTAC
GCTGATCAAATCACGTTGAATGCGTTGCAGCAAAGTGCCCATGCGGCCCGCAGTATTGTTCGTGACACTGGCAACGGCAA
AGTCCATACCTTGGGTGAGATTGCCTATCAAGCCTTGTACCCGTTGCTTGATCCACTACAAAGCCTATCGCGGGAAGATA
AAATTGCCTTGTTACATCGGGTCGATAAAGTCGCTCGCGCCGCCGATAAACGGGTGCAGGAAGTTAGCGCCAGTCTGACC
GGCGTGTATGAACAGATTCTGGTGGCTGCGACTGACGGCACCTTGGCTGCCGATGTGCGTCCGTTGGTCCGTCTTTCGGT
CAGTGTACTGGTGGAAGATAACGGCAAACGTGAACGCGGTGCTTGCGGTGGCGGTGGCCGTTTCGGTTATGACTATTTCC
TTGAAACCGTTGATGGCGAAGTGCGGGCAGATAATTTTGCTAATGAAGCGGTCAGAATGGCGCTGGTTAATCTTTCGGCT
ATTGCCGCTCCAGCGGGTGCGATGCCGGTAGTGTTAGGCGCAGGTTGGCCGGGCGTGCTGTTACATGAAGCGGTTGGTCA
CGGGTTGGAAGGTGATTTCAACCGTCGAGGCAGTTCGGTATTCAGTGGGCAAATGGGCAAATTGGTGGCTTCAGAACTCT
GTACGGTGGTGGACGATGGCACCATGCAAGGCCGCCGTGGCTCACTGGCTATCGACGATGAAGGGGTGCCGGGTCAATAT
AACGTGTTGATAGAAAATGGCATTCTGAAAGGGTATATGCAGGATAAACTGAACGCGCGTCTGATGGGGGTAGCCCCAAC
CGGTAATGGCCGTCGTGAATCCTATGCGCACCTGCCGATGCCACGCATGACCAACACCTATATGCTGGCAGGACAATCGA
CACCGGAAGATATTATCGCCAGCGTGGAGTACGGCCTGTATGCGCCAAATTTTGGTGGCGGTCAGGTGGATATCACCTCT
GGCAAGTTTGTCTTCTCAACGTCGGAAGCGTACTTAATCGAAAAAGGCAAAATCACTCACGCGGTGAAAGGGGCCACCCT
GATTGGCTCTGGCATTGAAGCGATGCAGCAGATTTCCATGGTCGGCAACGATCTGGCGCTGGATAAAGGCGTTGGTGTTT
GTGGCAAAGAGGGCCAAAGCCTGCCGGTGGGTGTCGGCCAACCCACGTTGAAGTTGGATAATTTAACCGTGGGCGGCACG
GCGTAG

Upstream 100 bases:

>100_bases
AAATGCCGGTCATGCAGCACAATCGCTTTCAGGCGACGCTGGAGCCGACATTGAATAAACCATTATTGAATAAACCACCA
TCTAATTAAGAGTAAAAACT

Downstream 100 bases:

>100_bases
AGGCGCTCGAAAATACAATATGGGTATTAGGCTTTGTTGGCACTGCATTTGATACTAAATTTAGTGCCAACAAAGCATCG
GTATATTAGTTAACCCTATT

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLSFVSEQLLTANKLNHQDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALYPLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLT
GVYEQILVAATDGTLAADVRPLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDGTMQGRRGSLAIDDEGVPGQY
NVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITS
GKFVFSTSEAYLIEKGKITHAVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
A

Sequences:

>Translated_481_residues
MSLSFVSEQLLTANKLNHQDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALYPLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLT
GVYEQILVAATDGTLAADVRPLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDGTMQGRRGSLAIDDEGVPGQY
NVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITS
GKFVFSTSEAYLIEKGKITHAVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
A
>Mature_480_residues
SLSFVSEQLLTANKLNHQDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAYA
DQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALYPLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLTG
VYEQILVAATDGTLAADVRPLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSAI
AAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDGTMQGRRGSLAIDDEGVPGQYN
VLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITSG
KFVFSTSEAYLIEKGKITHAVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=84.4074844074844, Blast_Score=808, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=408, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51190; Mature: 51058

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSFVSEQLLTANKLNHQDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSY
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEEHHHCCCCCC
NIDQGVGVRAVSGEKTGFAYADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALY
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
PLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLTGVYEQILVAATDGTLAADVR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
PLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
HHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDG
HHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCC
TMQGRRGSLAIDDEGVPGQYNVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CCCCCCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITSGKFVFSTSEAYLIEKGKITH
CCCCCEEEEECCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCEEE
AVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
HCCCCCEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
SLSFVSEQLLTANKLNHQDLFSVLGQLTERRLDYADLYFQSSYHEAWVLEDSIIKDGSY
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEEHHHCCCCCC
NIDQGVGVRAVSGEKTGFAYADQITLNALQQSAHAARSIVRDTGNGKVHTLGEIAYQALY
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
PLLDPLQSLSREDKIALLHRVDKVARAADKRVQEVSASLTGVYEQILVAATDGTLAADVR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
PLVRLSVSVLVEDNGKRERGACGGGGRFGYDYFLETVDGEVRADNFANEAVRMALVNLSA
HHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
IAAPAGAMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGSSVFSGQMGKLVASELCTVVDDG
HHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCC
TMQGRRGSLAIDDEGVPGQYNVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CCCCCCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGQSTPEDIIASVEYGLYAPNFGGGQVDITSGKFVFSTSEAYLIEKGKITH
CCCCCEEEEECCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCEEE
AVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDNLTVGGT
HCCCCCEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]