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The map label for this gene is ddg [H]

Identifier: 218930642

GI number: 218930642

Start: 4051516

End: 4052436

Strand: Reverse

Name: ddg [H]

Synonym: YPO3632

Alternate gene names: 218930642

Gene position: 4052436-4051516 (Counterclockwise)

Preceding gene: 218930649

Following gene: 218930641

Centisome position: 87.08

GC content: 51.68

Gene sequence:

>921_bases
ATGATAAAGCCGCAGAAATTCCATATTTCCCTGCTACACCCACGCTATTGGCTAACCTGGTTTGGCCTTGGCGTACTGTT
TTTGTTAGTTCAACTCCCTTACCCACTACTCAATAAGTTAGGTGTTTGGTTGGGGCGAACCTCCATGCGGTTCCTCAAAC
GGCGGGTTTCCATTGCCCGACGTAATCTTGAACTCTGTTTTCCTGACATGGATAAACAAGTCCTTGAGCAGACTATCATC
GGTAATTTCGAATCATTGGGCATGGGATTGCTGGAAACCGGGATGGCGTGGTTTTGGTCCGATACCCGGATACAGCGCTG
GTTTTCCGTCTCCGGTCTGGAGAACCTGAAACGCGCACAACAAGGTAAACGGGGCGTACTGGTCATTGGCGTCCATTTTA
TGTCATTAGAGCTGGGTGGCCGGGTCATGGGGCAATGTCAGCCAATGATGGCGATGTATCGCCCACACAACAATAAAGTG
ATGGAATTAGTGCAGACCTGGGGCCGTATGCGCTCCAACAAAGCGATGTTGGATCGGAGAGACCTGCGCGGTATGGTGCG
AGCCTTGAAGCAGGGTGAAGCGGTATGGTTTGCACCAGATCAAGATTATGGCCCGCGCGGCAGCGTTTTTGCACCACTGT
TCGCCGTAGAACATGCGGCAACCACCAGCGGCACCTTTATGCTCGCCCGTTTAGCAAAACCCGCACTGCTGCCCTTGGTT
TTATTGCGCAAAAAAGAGGGCCGTGGCTATGACCTGCTGATCCAACCCGCGCTGGAAGACTACCCGATTGACGATGAGAT
AGCCGCTGCCAGCTATATGAATAAAGTGATTGAGAAAGAGATCATGCGCGCGCCGGAACAATATCTTTGGTTACACCGCC
GCTTTAAAACCCGACCCATTGGCGAACCTTCGCTGTATTAA

Upstream 100 bases:

>100_bases
AAACGATGATTGACCACTGGTGTCAGAAGATATGTATCGCTATCGAGTTATGTCCTTATGCGTTACACACTCGCACTTAA
CGCATAACGATAGAGTTCAT

Downstream 100 bases:

>100_bases
TTTCACTTATTTATGTGAAAAATCAGACGGCTGACAAAGTCAAATGAAGGGGAAGCGTGCCGTTGGGGTCGTAGGAATCA
CAGCCCATTTCATTCTGTGG

Product: lipid A biosynthesis palmitoleoyl acyltransferase

Products: KDO2-(palmitoleoyl)-lipid IVA [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MIKPQKFHISLLHPRYWLTWFGLGVLFLLVQLPYPLLNKLGVWLGRTSMRFLKRRVSIARRNLELCFPDMDKQVLEQTII
GNFESLGMGLLETGMAWFWSDTRIQRWFSVSGLENLKRAQQGKRGVLVIGVHFMSLELGGRVMGQCQPMMAMYRPHNNKV
MELVQTWGRMRSNKAMLDRRDLRGMVRALKQGEAVWFAPDQDYGPRGSVFAPLFAVEHAATTSGTFMLARLAKPALLPLV
LLRKKEGRGYDLLIQPALEDYPIDDEIAAASYMNKVIEKEIMRAPEQYLWLHRRFKTRPIGEPSLY

Sequences:

>Translated_306_residues
MIKPQKFHISLLHPRYWLTWFGLGVLFLLVQLPYPLLNKLGVWLGRTSMRFLKRRVSIARRNLELCFPDMDKQVLEQTII
GNFESLGMGLLETGMAWFWSDTRIQRWFSVSGLENLKRAQQGKRGVLVIGVHFMSLELGGRVMGQCQPMMAMYRPHNNKV
MELVQTWGRMRSNKAMLDRRDLRGMVRALKQGEAVWFAPDQDYGPRGSVFAPLFAVEHAATTSGTFMLARLAKPALLPLV
LLRKKEGRGYDLLIQPALEDYPIDDEIAAASYMNKVIEKEIMRAPEQYLWLHRRFKTRPIGEPSLY
>Mature_306_residues
MIKPQKFHISLLHPRYWLTWFGLGVLFLLVQLPYPLLNKLGVWLGRTSMRFLKRRVSIARRNLELCFPDMDKQVLEQTII
GNFESLGMGLLETGMAWFWSDTRIQRWFSVSGLENLKRAQQGKRGVLVIGVHFMSLELGGRVMGQCQPMMAMYRPHNNKV
MELVQTWGRMRSNKAMLDRRDLRGMVRALKQGEAVWFAPDQDYGPRGSVFAPLFAVEHAATTSGTFMLARLAKPALLPLV
LLRKKEGRGYDLLIQPALEDYPIDDEIAAASYMNKVIEKEIMRAPEQYLWLHRRFKTRPIGEPSLY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=306, Percent_Identity=66.9934640522876, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1787292, Length=301, Percent_Identity=59.1362126245847, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788161, Length=307, Percent_Identity=26.7100977198697, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 35382; Mature: 35382

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPQKFHISLLHPRYWLTWFGLGVLFLLVQLPYPLLNKLGVWLGRTSMRFLKRRVSIAR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNLELCFPDMDKQVLEQTIIGNFESLGMGLLETGMAWFWSDTRIQRWFSVSGLENLKRAQ
HCHHEECCCCCHHHHHHHHHCCHHHHCHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHH
QGKRGVLVIGVHFMSLELGGRVMGQCQPMMAMYRPHNNKVMELVQTWGRMRSNKAMLDRR
CCCCCEEEEEEEEEHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHH
DLRGMVRALKQGEAVWFAPDQDYGPRGSVFAPLFAVEHAATTSGTFMLARLAKPALLPLV
HHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHH
LLRKKEGRGYDLLIQPALEDYPIDDEIAAASYMNKVIEKEIMRAPEQYLWLHRRFKTRPI
HHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GEPSLY
CCCCCC
>Mature Secondary Structure
MIKPQKFHISLLHPRYWLTWFGLGVLFLLVQLPYPLLNKLGVWLGRTSMRFLKRRVSIAR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNLELCFPDMDKQVLEQTIIGNFESLGMGLLETGMAWFWSDTRIQRWFSVSGLENLKRAQ
HCHHEECCCCCHHHHHHHHHCCHHHHCHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHH
QGKRGVLVIGVHFMSLELGGRVMGQCQPMMAMYRPHNNKVMELVQTWGRMRSNKAMLDRR
CCCCCEEEEEEEEEHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHH
DLRGMVRALKQGEAVWFAPDQDYGPRGSVFAPLFAVEHAATTSGTFMLARLAKPALLPLV
HHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHH
LLRKKEGRGYDLLIQPALEDYPIDDEIAAASYMNKVIEKEIMRAPEQYLWLHRRFKTRPI
HHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GEPSLY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; palmitoleoyl-ACP [C]

Specific reaction: KDO2-lipid IVA + palmitoleoyl-ACP = KDO2-(palmitoleoyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]