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The map label for this gene is rbsK [H]

Identifier: 218930631

GI number: 218930631

Start: 4038570

End: 4039502

Strand: Reverse

Name: rbsK [H]

Synonym: YPO3621

Alternate gene names: 218930631

Gene position: 4039502-4038570 (Counterclockwise)

Preceding gene: 218930632

Following gene: 218930630

Centisome position: 86.8

GC content: 53.8

Gene sequence:

>933_bases
GTGATGAGTGTATTTATTCTCGGCAGCTATGCGAAAGCGCTGGTGATGACCACCGACCGTATTCCTCTGGCTGGGGAAAC
GCTGATTGGCTATGACTTTCGCCAGACGTGGGGCGGTAAAGGCTCGGATATGGCGGTTCAGGCAGTGCGTCTGGGGGCAG
AGGTCGCCTATGCGGGTGTCGTCGGTGATGACACCTTTGGCCATGAATTTGTCGGCTTGATGCAGGAAGAAGGCGTCAAT
ATCGACGCATTAACCATCAGCGGAGAATTACCAACGGGGGCGGGACTTATCGTTAAAGATAAAGAAGCCCGTAACGTGAT
TGTCGTGGATATGGGGGCCAATAAACTGTTTACCCCAGCGTTGGTGGACAGCGCCTTATCCCAGCTCAAACAAAGCAATG
TGGTGCTCACACAGCTTGAAATTCCGCTGGAAACGGCACGTTACGGACTCCAACGGGCAAAAGAATTCGGCAAAATAACC
ATCCTGAACCCGGCTCCGGCAAGGGATCTGCGCGGTCTCGATCTCAGCGCGATTGATTATTTGACCCCTAATGAAACGGA
AGCCCGCGTGGCTCTGGGTCTGCCTCCGGATGACCCACGCAGCAACCGAGAGATTGCCAACCTCTTACTGGAAACCGGTT
GCCAATATGTCGTGATGACGCTGGGTGAATCAGGTTCTGCGGTATTTGGTCGCAACGACACACAAGAAATCCCCCCCTGC
ATCATTGATGTCGTCGACAGTAACGGTGCAGGTGACAGCTTTAACGCGGCACTGGCCGTCGCGCTGGATGAAGGGCTGCC
GATTAGCGAAGCTGTGCTGTTTGCTAACGCCACGGCGGCGTTGTGCTGTATGGATTGGGAAACGGTTCCGTCCTATCGCT
ACCGCGAAGATGTCGATGCTTTTATGCGATCTATAACCGTGAAAGAGGAATAA

Upstream 100 bases:

>100_bases
GGGGGTACTGCTGCTAGACAAATGAATAACAAACAGATTTCGCAAATGAATAACAAACAAACTATGCAATGAATAACAAA
CAGCACAGTTAAAGGAGTAT

Downstream 100 bases:

>100_bases
CAATAATGAGACCCGATAGAATCTTACACCCTGAACTTGCCGCCGCTTTAGCCACCTTAGGCCATACCGACATTATATTG
GTCACGGATGCAGGCTTCCC

Product: putative carbohydrate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MMSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTFGHEFVGLMQEEGVN
IDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPALVDSALSQLKQSNVVLTQLEIPLETARYGLQRAKEFGKIT
ILNPAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPC
IIDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAFMRSITVKEE

Sequences:

>Translated_310_residues
MMSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTFGHEFVGLMQEEGVN
IDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPALVDSALSQLKQSNVVLTQLEIPLETARYGLQRAKEFGKIT
ILNPAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPC
IIDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAFMRSITVKEE
>Mature_310_residues
MMSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTFGHEFVGLMQEEGVN
IDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPALVDSALSQLKQSNVVLTQLEIPLETARYGLQRAKEFGKIT
ILNPAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPC
IIDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAFMRSITVKEE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=33.7837837837838, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=35, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87082343, Length=290, Percent_Identity=26.2068965517241, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081971, Length=280, Percent_Identity=26.7857142857143, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=33.5616438356164, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=328, Percent_Identity=27.7439024390244, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20128807, Length=267, Percent_Identity=33.7078651685393, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=24.7557003257329, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33255; Mature: 33255

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS00059 ADH_ZINC ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGV
CEEEEEECCCCEEEEEEECCCCCCCCEEECCCHHHHCCCCCCCHHHHHHHHCCCEEEEEE
VGDDTFGHEFVGLMQEEGVNIDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPA
ECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCCHH
LVDSALSQLKQSNVVLTQLEIPLETARYGLQRAKEFGKITILNPAPARDLRGLDLSAIDY
HHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEC
LTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPC
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCE
IIDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDA
EEEEECCCCCCCCCCEEEEEEECCCCCHHHHEEEECCCEEEEEECCCCCCCCHHHHHHHH
FMRSITVKEE
HHHHCCCCCC
>Mature Secondary Structure
MMSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGV
CEEEEEECCCCEEEEEEECCCCCCCCEEECCCHHHHCCCCCCCHHHHHHHHCCCEEEEEE
VGDDTFGHEFVGLMQEEGVNIDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPA
ECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCCHH
LVDSALSQLKQSNVVLTQLEIPLETARYGLQRAKEFGKITILNPAPARDLRGLDLSAIDY
HHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEC
LTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPC
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCE
IIDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDA
EEEEECCCCCCCCCCEEEEEEECCCCCHHHHEEEECCCEEEEEECCCCCCCCHHHHHHHH
FMRSITVKEE
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]