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The map label for this gene is clpB2 [H]

Identifier: 218930609

GI number: 218930609

Start: 4006884

End: 4009487

Strand: Direct

Name: clpB2 [H]

Synonym: YPO3599

Alternate gene names: 218930609

Gene position: 4006884-4009487 (Clockwise)

Preceding gene: 218930608

Following gene: 218930610

Centisome position: 86.1

GC content: 53.15

Gene sequence:

>2604_bases
ATGATTCAAATTGACTTGCCCACACTCGTAAACCGCCTTAATCCCATTGCCCGCCATTCTCTGGAAGCGGCGGCGGCGCA
TTGCGTCAGTCAGCAGGAAGCTGAAATTACGGTCTCCCAAGTGCTACTGCAAATGATCTCCACACCATTATGTGATGTCA
GGTTAATCCTGAGCCATGCGGGTGTTGAGGAGGATGAACTACGGGAGTCGCTCGATCAACGTGTTTCAGGCTATCAAGCT
ATTACCCAGGCCTACCCGAGTTTTTCCCCATTACTGGTGGAATGGTTACAAGACAGTTGGTTGCTGGCATCGACAGAGAT
GGAACACAGCCAACTCCGTAGCGGCGTGATGTTATTGACGTTGTTGCTCAGCCCGTCGCGCTATCTGGTCCCCACGGCCA
ACCGGCTACTGTCTCCGATTAACCGTGAGTTACTGCGTCAGAATTTTGCTAACTGGACGGCAGACTCAGCAGAAACACCG
CGAGCAGAAAAAGGGGCTGAAGCTGGCAACGGCGCAGAAATCAATGGTGACAGCTTGCTGGCCCGCTATGCCAGCAATAT
GACCGAACAGGCCCGTAACGGGGAATTAGACCCTGTGCTGTGTCGGGATACCGAAATCGATCTGATGATCGATATTCTGT
GCCGCCGCCGCAAAAATAACCCGATAGTGGTGGGTGAAGCGGGGGTAGGGAAAAGTGCGCTGATCGAAGGTTTAGCCCTG
CGTATCGTGGATAATCAGGTGCCAGAAAAACTGCGTAACAGCGAGTTGATGACGCTGGATTTAGGCGCGCTTCAGGCTGG
CGCGGCAGTGAAAGGCGAATTTGAGAAGCGTTTCAAGGGCATCATGGCGGAAATTGCGCAGTCCACGACGCCAATTATCC
TGTTTATTGATGAAGCACACACGCTGATCGGGGCCGGTAACCAACAGGGCGGGTTAGACATTTCCAATCTGCTCAAACCC
GCTTTAGCGCGTGGTGAACTGAAAACGATTGCGGCAACCACCTGGAGCGAATACAAAAAATACTTTGAAAAAGATGCTGC
GCTGTCGCGCCGTTTCCAGTTGGTCAAAGTTTCTGAACCCAGCGCGCAAGAGGCCACGATTATCATGCGTGGCCTACGTA
CAGTTTATGAACAGGCGCATGGCGTCCTGATCGATGATGAAGCATTGCAAGCTGCGGCGGTGCTCAGTGACCGCTATATT
TCAGGGCGGCAGTTGCCAGATAAAGCCATCGACGTGTTAGATACCGCAGCCGCACGTGTTGCCATCAATCTCACCTCTGC
ACCGCGTCAGGTTTCGGCACTGAAAAACGAACTCTACCATCAGGGGATGGAAATCGAGATGCTGGAGCGGGAGCAACGCC
TCAGCTTAAGCCGCCCGGATGAGCGGTTATCCGTTTTACAACAGCAGCGAATTGAGATCGAACAGCAACTCATTGCCCTG
AATACCGGTTGGGAAAAGCAACAACATTTGGTCCAGCAGATTATCGCACTGAGAGCGGTCCTGTTGGCACAAGAAGAGAG
CGCCACAGATGAGCAAGTGGTCAATCTGACAGCGTTGAGCGATGAGTTGGAACGGTTGCAACAGCACCAGACGCTGGTCT
CGCCCCATGTGGATAAGAGCCAGATTGCGGCGGTGATCGCGGAATGGACCGGTGTACCGCTAAACCGCCTTTCTCAGAGT
GAATTGGCGGTGGTTACTGAATTGCCCTCTTATCTGGGGCAGCAGATCAAAGGACAAGAGACGGCTATCCATTGCTTGCA
CCAACACTTGCTGACCGCAAGGGCGGATTTACGTCGCCCAGGTCGCCCAATGGGGGCTTTCCTGTTGGTTGGGCCTAGCG
GCGTGGGTAAAACGGAAACCGTGCTACAGATTGCCGACCTGCTCTATGGTGGCCGCCAATATCTCACCACCATCAATATG
TCCGAATTCCAAGAGAAGCATACCGTCTCGCGCCTGATTGGTTCACCTCCGGGCTACGTCGGGTATGGTGAAGGCGGCGT
ACTGACCGAAGCCATTCGCCAAAAACCTTACTCGGTAGTGCTACTGGATGAAGTGGAAAAAGCCCACCCCGATGTGCTGA
ATCTGTTTTATCAGGCCTTCGATAAGGGCGAGTTGGCGGACGGTGAAGGCCGCATCATCGATTGCAAAAATATCGTATTT
TTCCTGACCTCCAATCTGGGATACCAGACCATTGTTGATCATGCAGACGAGCCTGCATTGCTCAATGAACGGCTCTACCC
CGAGCTATCGGCATTCTTTAAACCTGCGCTACTGGCCCGCATGGAAGTGGTTCCTTATCTGCCGCTGGGCATGGAAACGC
TGCAAATTATCATTCACGGCAAACTGAACCGTCTGGATACGCTGCTGCGCCAACGCTTTAGTGCTGATGTGGTCATTGAA
CCTGAAGTGATCGACGAAATCCTGCTACGCGCGACCCGTGCCGAAAATGGTGCGCGTATGCTCGAGTCGATTATCGACGG
TGCGCTATTACCACCGGTTTCTCTGTTGTTATTACAGAAAGTGGCCGCTGGCACCGCTATCAGCCACATTCGGATCGCGG
TAGAGGGGAATGTGTTTACTGCACAGGTTGAGGGAGCGATATGA

Upstream 100 bases:

>100_bases
CTGCTGGTGGTGATTTATCTGTTTTATGCCATCCACCTGCACACCCAAAGTCAGGATATTTTGCAACAGCTAAACAATTT
ATTGAGCTAGGAAAGCACAA

Downstream 100 bases:

>100_bases
GACAACGGTTAAAGAGTGTCCTCGCACTGCTGGACAATGACTCAACCGAACAACTGATCCATCGCTTTCTGACGATTAAC
CACCACCGCCAACGATTTAG

Product: Clp ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 867; Mature: 867

Protein sequence:

>867_residues
MIQIDLPTLVNRLNPIARHSLEAAAAHCVSQQEAEITVSQVLLQMISTPLCDVRLILSHAGVEEDELRESLDQRVSGYQA
ITQAYPSFSPLLVEWLQDSWLLASTEMEHSQLRSGVMLLTLLLSPSRYLVPTANRLLSPINRELLRQNFANWTADSAETP
RAEKGAEAGNGAEINGDSLLARYASNMTEQARNGELDPVLCRDTEIDLMIDILCRRRKNNPIVVGEAGVGKSALIEGLAL
RIVDNQVPEKLRNSELMTLDLGALQAGAAVKGEFEKRFKGIMAEIAQSTTPIILFIDEAHTLIGAGNQQGGLDISNLLKP
ALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPSAQEATIIMRGLRTVYEQAHGVLIDDEALQAAAVLSDRYI
SGRQLPDKAIDVLDTAAARVAINLTSAPRQVSALKNELYHQGMEIEMLEREQRLSLSRPDERLSVLQQQRIEIEQQLIAL
NTGWEKQQHLVQQIIALRAVLLAQEESATDEQVVNLTALSDELERLQQHQTLVSPHVDKSQIAAVIAEWTGVPLNRLSQS
ELAVVTELPSYLGQQIKGQETAIHCLHQHLLTARADLRRPGRPMGAFLLVGPSGVGKTETVLQIADLLYGGRQYLTTINM
SEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGELADGEGRIIDCKNIVF
FLTSNLGYQTIVDHADEPALLNERLYPELSAFFKPALLARMEVVPYLPLGMETLQIIIHGKLNRLDTLLRQRFSADVVIE
PEVIDEILLRATRAENGARMLESIIDGALLPPVSLLLLQKVAAGTAISHIRIAVEGNVFTAQVEGAI

Sequences:

>Translated_867_residues
MIQIDLPTLVNRLNPIARHSLEAAAAHCVSQQEAEITVSQVLLQMISTPLCDVRLILSHAGVEEDELRESLDQRVSGYQA
ITQAYPSFSPLLVEWLQDSWLLASTEMEHSQLRSGVMLLTLLLSPSRYLVPTANRLLSPINRELLRQNFANWTADSAETP
RAEKGAEAGNGAEINGDSLLARYASNMTEQARNGELDPVLCRDTEIDLMIDILCRRRKNNPIVVGEAGVGKSALIEGLAL
RIVDNQVPEKLRNSELMTLDLGALQAGAAVKGEFEKRFKGIMAEIAQSTTPIILFIDEAHTLIGAGNQQGGLDISNLLKP
ALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPSAQEATIIMRGLRTVYEQAHGVLIDDEALQAAAVLSDRYI
SGRQLPDKAIDVLDTAAARVAINLTSAPRQVSALKNELYHQGMEIEMLEREQRLSLSRPDERLSVLQQQRIEIEQQLIAL
NTGWEKQQHLVQQIIALRAVLLAQEESATDEQVVNLTALSDELERLQQHQTLVSPHVDKSQIAAVIAEWTGVPLNRLSQS
ELAVVTELPSYLGQQIKGQETAIHCLHQHLLTARADLRRPGRPMGAFLLVGPSGVGKTETVLQIADLLYGGRQYLTTINM
SEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGELADGEGRIIDCKNIVF
FLTSNLGYQTIVDHADEPALLNERLYPELSAFFKPALLARMEVVPYLPLGMETLQIIIHGKLNRLDTLLRQRFSADVVIE
PEVIDEILLRATRAENGARMLESIIDGALLPPVSLLLLQKVAAGTAISHIRIAVEGNVFTAQVEGAI
>Mature_867_residues
MIQIDLPTLVNRLNPIARHSLEAAAAHCVSQQEAEITVSQVLLQMISTPLCDVRLILSHAGVEEDELRESLDQRVSGYQA
ITQAYPSFSPLLVEWLQDSWLLASTEMEHSQLRSGVMLLTLLLSPSRYLVPTANRLLSPINRELLRQNFANWTADSAETP
RAEKGAEAGNGAEINGDSLLARYASNMTEQARNGELDPVLCRDTEIDLMIDILCRRRKNNPIVVGEAGVGKSALIEGLAL
RIVDNQVPEKLRNSELMTLDLGALQAGAAVKGEFEKRFKGIMAEIAQSTTPIILFIDEAHTLIGAGNQQGGLDISNLLKP
ALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPSAQEATIIMRGLRTVYEQAHGVLIDDEALQAAAVLSDRYI
SGRQLPDKAIDVLDTAAARVAINLTSAPRQVSALKNELYHQGMEIEMLEREQRLSLSRPDERLSVLQQQRIEIEQQLIAL
NTGWEKQQHLVQQIIALRAVLLAQEESATDEQVVNLTALSDELERLQQHQTLVSPHVDKSQIAAVIAEWTGVPLNRLSQS
ELAVVTELPSYLGQQIKGQETAIHCLHQHLLTARADLRRPGRPMGAFLLVGPSGVGKTETVLQIADLLYGGRQYLTTINM
SEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGELADGEGRIIDCKNIVF
FLTSNLGYQTIVDHADEPALLNERLYPELSAFFKPALLARMEVVPYLPLGMETLQIIIHGKLNRLDTLLRQRFSADVVIE
PEVIDEILLRATRAENGARMLESIIDGALLPPVSLLLLQKVAAGTAISHIRIAVEGNVFTAQVEGAI

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=320, Percent_Identity=33.4375, Blast_Score=159, Evalue=8e-39,
Organism=Escherichia coli, GI1788943, Length=662, Percent_Identity=42.2960725075529, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1787109, Length=274, Percent_Identity=44.5255474452555, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323002, Length=698, Percent_Identity=36.676217765043, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6320464, Length=686, Percent_Identity=37.0262390670554, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95659; Mature: 95659

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIDLPTLVNRLNPIARHSLEAAAAHCVSQQEAEITVSQVLLQMISTPLCDVRLILSHA
CEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GVEEDELRESLDQRVSGYQAITQAYPSFSPLLVEWLQDSWLLASTEMEHSQLRSGVMLLT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHH
LLLSPSRYLVPTANRLLSPINRELLRQNFANWTADSAETPRAEKGAEAGNGAEINGDSLL
HHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ARYASNMTEQARNGELDPVLCRDTEIDLMIDILCRRRKNNPIVVGEAGVGKSALIEGLAL
HHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
RIVDNQVPEKLRNSELMTLDLGALQAGAAVKGEFEKRFKGIMAEIAQSTTPIILFIDEAH
HHHHHHHHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TLIGAGNQQGGLDISNLLKPALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEP
CEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
SAQEATIIMRGLRTVYEQAHGVLIDDEALQAAAVLSDRYISGRQLPDKAIDVLDTAAARV
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHE
AINLTSAPRQVSALKNELYHQGMEIEMLEREQRLSLSRPDERLSVLQQQRIEIEQQLIAL
EEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NTGWEKQQHLVQQIIALRAVLLAQEESATDEQVVNLTALSDELERLQQHQTLVSPHVDKS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QIAAVIAEWTGVPLNRLSQSELAVVTELPSYLGQQIKGQETAIHCLHQHLLTARADLRRP
HHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
GRPMGAFLLVGPSGVGKTETVLQIADLLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYV
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHHHHHHCCCCCCC
GYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGELADGEGRIIDCKNIVF
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEECCCEEE
FLTSNLGYQTIVDHADEPALLNERLYPELSAFFKPALLARMEVVPYLPLGMETLQIIIHG
EEECCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
KLNRLDTLLRQRFSADVVIEPEVIDEILLRATRAENGARMLESIIDGALLPPVSLLLLQK
CHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHH
VAAGTAISHIRIAVEGNVFTAQVEGAI
HHHCCCEEEEEEEEECCEEEEEECCCC
>Mature Secondary Structure
MIQIDLPTLVNRLNPIARHSLEAAAAHCVSQQEAEITVSQVLLQMISTPLCDVRLILSHA
CEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GVEEDELRESLDQRVSGYQAITQAYPSFSPLLVEWLQDSWLLASTEMEHSQLRSGVMLLT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHH
LLLSPSRYLVPTANRLLSPINRELLRQNFANWTADSAETPRAEKGAEAGNGAEINGDSLL
HHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ARYASNMTEQARNGELDPVLCRDTEIDLMIDILCRRRKNNPIVVGEAGVGKSALIEGLAL
HHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
RIVDNQVPEKLRNSELMTLDLGALQAGAAVKGEFEKRFKGIMAEIAQSTTPIILFIDEAH
HHHHHHHHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TLIGAGNQQGGLDISNLLKPALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEP
CEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
SAQEATIIMRGLRTVYEQAHGVLIDDEALQAAAVLSDRYISGRQLPDKAIDVLDTAAARV
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHE
AINLTSAPRQVSALKNELYHQGMEIEMLEREQRLSLSRPDERLSVLQQQRIEIEQQLIAL
EEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NTGWEKQQHLVQQIIALRAVLLAQEESATDEQVVNLTALSDELERLQQHQTLVSPHVDKS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QIAAVIAEWTGVPLNRLSQSELAVVTELPSYLGQQIKGQETAIHCLHQHLLTARADLRRP
HHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
GRPMGAFLLVGPSGVGKTETVLQIADLLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYV
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHHHHHHCCCCCCC
GYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGELADGEGRIIDCKNIVF
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEECCCEEE
FLTSNLGYQTIVDHADEPALLNERLYPELSAFFKPALLARMEVVPYLPLGMETLQIIIHG
EEECCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
KLNRLDTLLRQRFSADVVIEPEVIDEILLRATRAENGARMLESIIDGALLPPVSLLLLQK
CHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHH
VAAGTAISHIRIAVEGNVFTAQVEGAI
HHHCCCEEEEEEEEECCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]